Clinical trials: Lens Implantation, Intraocular
Aphakia, Cataract
One-Piece Hydrophobic Acrylic Intraocular Lens in Subjects Undergoing Cataract Extraction
The objective of this study is to evaluate the safety and effectiveness of the enVista® One-Piece Hydrophobic Acrylic intraocular lens (IOL), following primary implantation for the visual correction of aphakia in adults 18 years…
- Trial name
- NCT01230060
- Testing
- enVista
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract, Presbyopia Correction
Night Driving After Trifocal Versus Monofocal IOL Implantation
This prospective observational cohort study will compare night-driving visual difficulty and visual disturbances after bilateral implantation of an Alcon trifocal intraocular lens or an Alcon monofocal intraocular lens in adults…
- Trial name
- TriIOL (NCT07755189)
- Testing
- AcrySof IQ PanOptix TFNT00 Trifocal Intraocular Lens, Alcon Monofocal Intraocular Lens
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Jin Yang
IOL, Cataract
Post-Market Clinical Follow-Up Study on the Rotational Stability of an Intraocular Lens After Cataract Surgery
The goal of this post-market, prospective study at multiple clinics is to evaluate the rotational stability of the RayOne Model RAO800S non-toric monofocal intraocular lens with orientation marks in adult patients undergoing…
- Trial name
- NCT07099079
- Volunteers
- 92 people
- Sponsor
- Rayner Intraocular Lenses Limited
Cataract
Clinical Safety and Efficacy of Hydrophilic Acrylic Intraocular Lenses
Clinical safety and efficacy of CT ASPHINA 409 IOLs after implantation
- Trial name
- UVEA409 (NCT03145103)
- Testing
- CT ASPHINA 409
- Where
- Sweden
- Volunteers
- 282 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract, Lens Opacities
PMCF Retrospective Study Outcomes of a Monofocal Toric Intraocular Lens
This is a monocentric retrospective, open-label clinical study in patients after unilateral or bilateral implantation of hydrophobic acrylic monofocal toric intraocular lens PODEYE TORIC and executed only with standard of care…
- Conditions
- Cataract, Lens Opacities, Astigmatism
- Trial name
- NCT05055076
- Testing
- PODEYE TORIC
- Where
- France
- Volunteers
- 105 people
- Sponsor
- Beaver-Visitec International, Inc.
Capsular Contracture, Implant, Pediatric Cataract
Capsular Outcomes of Pediatric Cataract Surgery With Primary Intraocular Lens Implantation
Lens capsular often changes after pediatric cataract surgery，causing complications such as anterior capsulerhexis shrinkage, visual axis opacification (VAO), zonular dehiscence and so on.
- Trial name
- capsular (NCT04803097)
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Yune Zhao
Cataract, Astigmatism
A Trial of Toric Versus Non-toric Intraocular Lenses in Phacoemulsification Cataract Surgery
This is a randomised controlled trial that formally compares intra-ocular lenses, which can be used in cataract surgery, one of which is the standard 'monofocal' lens, and the other is the newer toric lens which can correct…
- Trial name
- NCT01712503
- Testing
- Phacoemulsfication cataract surgery and intra-ocular lens implant
- Where
- United Kingdom
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Western Sussex Hospitals NHS Trust
Cataract, Presbyopia Correction
Visual Quality and Performance of Eyes With Asqelio™ EDoF Toric Lenses
This study evaluates the optical quality and clinical performance of the Asqelio™ EDOF Toric intraocular lens (IOL) in patients undergoing cataract surgery or refractive lensectomy.
- Trial name
- NCT06707545
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- AST Products, Inc.
Cataract
Evaluation of the Rotational Stability
To evaluate rotational stability of the investigational device implanted after cataract surgery.
- Trial name
- NCT03247751
- Testing
- intraocular lens
- Volunteers
- 95 people
- Sponsor
- Nidek Co. LTD.
Aphakia, Presbyopia
Real-World Study of Vivity Intraocular Lenses (IOLs)
The primary objective of this clinical study is to assess the clinical performance of the AcrySof IQ Vivity Extended Vision IOL in a Chinese population.
- Trial name
- NCT04800016
- Testing
- AcrySof IQ Vivity Extended Vision IOL, Cataract surgery
- Where
- China
- Sponsor
- Alcon Research
Cataracts, Cataract Surgery
Endothelial Cell Loss and Induced Astigmatism After Wound-directed and Wound-assisted IOL Injection
The purpose of this study is to determine if there is any difference in astigmatism (eye surface curvature) or corneal endothelial cell density (the inner cell lining of the eye surface) after two different methods for inserting…
- Trial name
- NCT01250964
- Testing
- Lens insertion during cataract surgery
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of North Carolina, Chapel Hill
Cataract
A Clinical Study Comparing Postoperative Outcomes Between the TECNIS Intraocular Lens.
This is a prospective, multi-center, masked, three-arm, randomized clinical study of the TECNIS Eyhance Toric II IOL (test #1) and TECNIS Synergy Toric II (test #2) compared to the TECNIS Toric 1-Piece IOL (control).
- Trial name
- NCT05396599
- Testing
- Model DIU, Model DFW, Model ZCT
- Where
- 5 sites in United States
- Volunteers
- 35 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Cataract Senile
Evaluation of a Trifocal Lens
Evaluation of the clinical safety and effectiveness of hydrophilic acrylic intraocular lens
- Trial name
- NCT04545671
- Testing
- trifocal lens
- Where
- Germany
- Volunteers
- 389 people
- Sponsor
- Carl Zeiss Meditec AG
Pterygium, Cataract
Effect of Pterygium Excision on Intraocular Lens Power Calculation for Subsequent Cataract Operation
Pterygium is known to induce with-the-rule astigmatism. Excision of pterygium will steepen the cornea and reduce corneal astigmatism.
- Conditions
- Pterygium, Cataract, Astigmatism
- Trial name
- NCT00563667
- Testing
- pterygium excision
- Where
- 3 sites in China
- Volunteers
- 40 people
- Sponsor
- Hospital Authority, Hong Kong
Intraocular Lens
Comparison of Two Different Methods for Calculating Intraocular Lens Tilt and Decentration
Agreement and Reproducibility of Intraocular Lens Tilt and Decentration Measurements: A Comparison between CASIA2 and CILT
- Trial name
- NCT07025707
- Where
- Austria
- Volunteers
- 15 people
- Sponsor
- St John of God Hospital, Vienna
Irregular Astigmatism, Astigmatism
Improving Visual Quality in Patients With Irregular Corneas Using Asymmetrical Toric Intraocular Lenses
Cataract surgery in patients with irregular corneas presents unique challenges, primarily due to the high variability in keratometry and corneal tomography measurements, which complicates accurate intraocular lens (IOL)…
- Conditions
- Irregular Astigmatism, Astigmatism, Cataract and IOL Surgery
- Trial name
- VITAL (NCT07294716)
- Testing
- AMILens Individual
- Where
- Austria
- Volunteers
- 15 people
- Sponsor
- Johannes Kepler University of Linz
Cataract, Corneal Astigmatism
Post-market Study to Obtain Surgeon Feedback on Clinical Outcome in Eyes Implanted With TECNIS Toric II IOL
This is a multicenter, prospective, single-arm, open-label, clinical study of the commercially available TECNIS Toric II, Model ZCU IOL.
- Trial name
- NCT04210232
- Testing
- TECNIS® TORIC II Intraocular Lens (IOL)
- Where
- 12 sites in United States
- Volunteers
- 54 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Cataract Surgery, Intraocular Lens Position
The Effect of Capsulotomy Size on Effective Lens Position in Robotic Laser Cataract Surgery
The goal of this clinical trial is to learn whether the size of the opening made during laser-assisted cataract surgery affects where the artificial lens sits in the eye and the glasses prescription after surgery.
- Conditions
- Cataract Surgery, Intraocular Lens Position, Refractive Outcomes After Cataract Surgery, Cataract
- Trial name
- PRECISE (NCT07856849)
- Testing
- Femtosecond Laser Capsulotomy - Small Size (4.6 mm), Femtosecond Laser Capsulotomy - Large Size (5.6 mm)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Twin Cities Eye Consultants
Refractive Error, Corneal Implantation
Piggyback Sulcoflex Toric IOL for Correcting Refractive Error Following Corneal Transplantation
A prospective study to evaluate the safety and efficacy of a piggyback sulcoflex toric intraocular lens in pseudophakic patients for correcting refractive errors following corneal transplantation
- Conditions
- Refractive Error, Corneal Implantation, Intraocular Lens Implantation
- Trial name
- NCT01718184
- Testing
- toric intraocular lens implantation, Sulcoflex intraocular lens implantation
- Where
- Israel
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Posterior Chamber Phakic Intraocular Lens, Vault
Study on the Diagnostic Efficacy of ICL Selection and Prediction Depth Model Based on Eye Images
To evaluate the diagnostic efficacy of deep learning network model in implantable collamer lens selection and prediction in a multicenter cross-sectional study
- Conditions
- Posterior Chamber Phakic Intraocular Lens, Vault, Deep Neural Network, Myopia
- Trial name
- NCT06669728
- Testing
- AI diagnostic algorithm
- Where
- China
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Nanchang University