Clinical trials: Lens Implantation, Intraocular
Cataract
A Comparison of Aspheric Toric Intraocular Lens (IOL) Implantation Versus Aspheric Non-Toric Lens Implantation
The purpose of this study was to evaluate and compare uncorrected distance visual acuity measurement in pseudophakic subjects with bilateral implantation of an AcrySof IQ Toric Intraocular Lens (IOL) versus bilateral implantation…
- Trial name
- NCT01225926
- Testing
- Toric T3 - T9, IQ SN60WF
- Volunteers
- 24 people
- Sponsor
- Alcon Research
Myopia, Astigmatism
Randomized, Prospective Comparison of the Outcome of Toric Implantable Contact Lens (TICL) and Q-LASIK for the Correction of Myopia With Astigmatism
The objective is to conduct a contralateral prospective clinical study to compare the safety, efficacy, and quality of vision of the STAAR Surgical Co.
- Trial name
- NCT01088568
- Testing
- the implantation of toric implantable collamer lens, customized laser-assisted in situ keratomileusis
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Cataract, Postoperative Complications
Validation of an Artificial Intelligence System for Postoperative Management of Cataract Patients
Cataract surgery is the current standard of management for cataract patients, which is typically succeeded by a postoperative follow-up schedule.
- Conditions
- Cataract, Postoperative Complications, Artificial Intelligence
- Trial name
- NCT04138771
- Testing
- An artificial intelligence system for postoperative management of cataract patients
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Sun Yat-sen University
Aphakia, Cataract
A Clinical Study to Evaluate The Safety and Effectiveness of The RxSight Light Adjustable Lens (LAL) In Subjects Desiring an Extended Depth of Focus
The primary objective of this study is to evaluate, for the visual correction of aphakia and presbyopia, the safety and effectiveness of the RxSight Light Adjustable Lens (LAL) to provide an extended depth of focus (improve…
- Conditions
- Aphakia, Cataract, Presbyopia
- Trial name
- NCT04177771
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD) - Pre-COVID Population, SofPort LI61AO IOL, Tecnis ZCB00 or ZTC150 IOL
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- RxSight, Inc.
Refractive Errors
Comparison of Higher Order Aberrations and Contrast Sensitivity Between Acrysof SN60AT, SN60WF and Restore Intraocular Lenses
This project involves evaluation of post operative contrast sensitivity and wavefront aberration results among patients implanted with standard monofocal lenses (Acrysof SN60AT/SN60WF) and the new presbyopic correcting multifocal…
- Trial name
- NCT00345085
- Testing
- Wavefront and Contrast Sensitivity
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Cataract
Clinical Investigation of the TECNIS 1-Piece Intraocular Lens
This study is a 6-month, prospective, comparative, multicenter, bilateral, parallel group, randomized (2:1), subject/evaluator masked clinical investigation of the investigational mDCB00 IOL as compared to the DCB00 IOL.
- Trial name
- NCT05090787
- Testing
- Investigational mDCB00, Control DCB00
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Cataract
Safety and Efficacy of the Bi-Aspheric Monofocal IOL
This is an observational, single-center, non-control, open-label post-marketing study. Patients implanted with an aspicio™ Monofocal Intraocular Lens will be scheduled for a follow-up visit at least 3 months after the surgery to…
- Trial name
- NCT06380478
- Testing
- aspicio Monofocal IOL
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- ICARES Medicus, Inc.
Corneal Endothelial Cell Loss, Secondary Intraocular Lens
Anterior Chamber Versus Scleral Fixated Intraocular Lens: Long-term Vision and Safety Outcomes
This is a prospective comparative non-randomized cohort study to understand the long-term vision outcomes, safety, and stability of anterior chamber intraocular lenses (AC IOLs) vs. scleral-fixated intraocular lenses (SF IOLs).
- Trial name
- NCT04072978
- Testing
- Intraocular lens implantation
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Presbyopia, Refractive Errors
Prospective Multicenter Clinical Study on the Visual and Refractive Outcomes and Safety Outcomes Following Implantation of an AddOn Intraocular Lens in Previously Pseudophakic Eyes
The purpose of this prospective multicenter clinical study is to evaluate the visual and refractive outcomes and safety outcomes following bilateral implantation of trifocal and/or trifocal toric 1stQ AddOn (Medicontur)…
- Conditions
- Presbyopia, Refractive Errors, Residual Astigmatism
- Trial name
- NCT05596682
- Testing
- supplementary intraocular lenses
- Where
- 4 sites in Belgium, France and 2 more
- Volunteers
- 75 people
- Sponsor
- Medicontur Medical Engineering Ltd
Aphakia
Clinical Study of a UV-Absorbing Acrylic Posterior Chamber Intraocular Lens
The purpose of this study is to assess the safety and efficacy of the HMY Model YA-60BB Intraocular Lens (IOL) when implanted in the posterior chamber of the human eye for the optical correction of aphakia following cataract…
- Trial name
- HMY (NCT00625313)
- Testing
- HMY Model YA-60BB IOL
- Where
- United States
- Volunteers
- 617 people, healthy volunteers welcome
- Sponsor
- Hoya Surgical Optics, Inc.
Cataract, Phakic Intraocular Lens Explantation
Molecular Background of Endothelial Cell Loss in Patients With Phakic Intraocular Lenses: a Tear and Aqueous Humour Analysis Study
Rationale: The number of highly myopic patients is increasing. Especially in East and Southeast Asia, up to 90% of adolescents are currently myopic.
- Trial name
- MoBack (NCT04174924)
- Testing
- Phakic intraocular lens (pIOL) explantation
- Where
- Netherlands
- Volunteers
- 126 people
- Sponsor
- Maastricht University Medical Center
Cataract
Clinical Investigation of AcrySof® IQ PanOptix™ IOL Model TFNT00
The purpose of this clinical study is to compare the visual outcomes of the AcrySof IQ PanOptix Multifocal Intraocular Lens (IOL) Model TFNT00 against that of a monofocal lens, the AcrySof Monofocal IOL Model SN60AT, in order to…
- Trial name
- NCT03280108
- Testing
- AcrySof IQ PanOptix Multifocal IOL, AcrySof Monofocal IOL
- Where
- 12 sites in United States
- Volunteers
- 250 people
- Sponsor
- Alcon Research
Cataract, Intraocular Lenses
The Effect of Eye Exercises on Visual Function and Quality of Life After Multifocal Intraocular Lens Implantation
The goal of this clinical trial is to examine the effects of eye exercises on visual function and quality of life in cataract patients undergoing multifocal intraocular lens implantation.
- Trial name
- NCT05958459
- Testing
- Eye Exercise, no intervention
- Volunteers
- 60 people
- Sponsor
- Idrıs Dogan
Cataract
Postoperative Discomfort and Ocular Redness Following Phacoemulsification Surgery
Primary objective of the study is the assessment of the patients' discomfort and ocular redness following cataract extraction surgery by means of phacoemulsification and intraocular lens implantation.
- Trial name
- NCT02558218
- Testing
- Systane Ultra, tobradex quid (Standard)
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- Democritus University of Thrace
Cataract
Clinical Evaluation Study for Assessing the Visual Performance of Hanita Lenses Trifocal IOL
Hanita Lenses Trifocal IOL, SeeLens AFR (Intensity IOL).Prospective, single-arm single-center, open-label study.
- Trial name
- NCT04843748
- Testing
- cataract surgery and intraocular lens implantation - both eyes
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Hanita Lenses
Cataract
Observational, Prospective Clinical Investigation on Mini 4 Ready Intraocular Lens
Cataract surgery presents an extremely high success rate in improving vision and quality of life and it is currently the most commonly performed ophthalmic surgery, especially considering its growing utility in the aging…
- Trial name
- NCT06093880
- Testing
- monofocal intraocular lens
- Where
- Italy
- Volunteers
- 125 people
- Sponsor
- SIFI SpA
to Compare the Effect of Two Types of IOLs, on the Incidence of Cystoid Macular Edema
The Effect of a Blue Light Filtering IOL
To compare the effect on blood retinal barrier disruption 3 and 12 months after implantation of either a blue light filtering intraocular lens(blue-filtering IOL) or an ultraviolet light filtering intraocular lens(UV-filtering…
- Conditions
- to Compare the Effect of Two Types of IOLs, on the Incidence of Cystoid Macular Edema, After Cataract Surgery
- Trial name
- NCT00571831
- Testing
- intraocular lens implantation
- Where
- Japan
- Volunteers
- 50 people
- Sponsor
- Showa University
Pseudophakic Bullous Keratopathy, Anterior Chamber Intraocular Lens
Descemet Membrane Endothelial Keratoplasty Combined With Intraocular Lens Exchange: Sequential Versus Combined Surgery
Surgical treatment of corneal endothelial decompensation in the presence of an anterior chamber intraocular lens (AC IOL) is technically challenging.
- Trial name
- NCT04344522
- Testing
- Descemet membrane endothelial keratoplasty DMEK, IOL exchange, iridoplasty
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Alexandria University
The Comparison of IOL Formulas in Eyes With PCE≥15um Undergoing Cataract Surgery
Comparison of IOL Formulas in Eyes With PCE≥15µm
The goal of this observational study is to evaluate the long-term refractive outcomes of advanced intraocular lens (IOL) power calculation formulas in cataract patients with posterior corneal elevation (PCE ≥ 15 μm).
- Trial name
- NCT07346456
- Testing
- Intraocular lens calculation formulas
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Cataract
Clinical Safety and Efficacy of CT ASPHINA 509 Lenses
Clinical safety and efficacy of CT ASPHINA 509 IOLs after implantation
- Trial name
- UVEA509 (NCT03145116)
- Testing
- CT ASPHINA 509
- Where
- Germany
- Volunteers
- 95 people
- Sponsor
- Carl Zeiss Meditec AG