Clinical trials: Lenses, Intraocular
Cataract
Efficacy of Dextenza Insert in Upper vs Lower Punctum Following Cataract Surgery With PCIOL.
To assess the safety and effectiveness of treatment with an intracanalicular dexamethasone (0.4mg) insert in the operating room following cataract surgery/intraocular lens implant (IOL) with or without iStent/Hydrus/Goniotomy…
- Trial name
- DEXTENZA (NCT05372315)
- Testing
- Dextenza 0.4Mg Ophthalmic Insert
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Iworks Laser and Vision Center
Myopia, High, With Cataract and Anterior Capsule Polished
The Influences Of Anterior Capsule Polishing On Anterior Capsular Changes and Intraocular Lenses Stability of Super High Myopic Eyes
A prospective study included 20 patients with super high myopia who underwent bilateral uneventful cataract. 360°anterior capsule polishing was performed with double-ended capsule polisher randomly in one eye, and the opposite…
- Trial name
- NCT03142269
- Testing
- 360°anterior capsule polishing
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- yin ying zhao
Cataract, Refractive Lens Exchange
Visual Performance of Patients Implanted With a Multifocal IOL
The goal of this clinical trial is to learn about the visual performance of a new multifocal intra-ocular lens in patients presenting for cataract or refractive lens exchange surgery.
- Trial name
- VISUAL (NCT06111222)
- Testing
- AT ELANA
- Where
- 3 sites in Germany, Spain
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec AG
Cataract
AMO's Tecnis™ Multifocal Intraocular Lenses (Tecnis MF), Alcon's ReStor Multifocal IOL
The purpose of this study is to compare the visual outcomes with bilateral implantation of Tecnis MF and ReSTOR IOLs Six months post cataract surgery.
- Trial name
- NCT01278420
- Testing
- Tecnis MF, ReSTOR
- Where
- 6 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
Intraocular Lens
Visual Outcomes and Contrast Sensitivity in Patients Implanted With Tecnis Eyhance Intraocular Lens
To compare visual outcomes for various distances, reading speed, contrast sensitivity, glare occurence, defocus curve and subjective satisfaction in patients implanted with the extended depth of focus lens (Tecnis Eyhance) in one…
- Trial name
- NCT04800887
- Testing
- TECNIS Eyhance intraocular lens, Monofocal intraocular lens Tecnis ZCB00
- Where
- Czechia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Toric Intraocular Lens Stability, Visual Quality
Toric Intraocular Lens (IOL) Implantation for Management of Cataracts
This study included cataract patients who underwent toric intraocular lens (IOL) implantation, which aimed to evaluate the stability and clinical visual quality of toric IOLs.
- Trial name
- NCT05797298
- Where
- 2 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Eye & ENT Hospital of Fudan University
Presbyopia, Pseudophakia
Visual Outcomes After Extended Depth of Focus Intraocular Lens Implantation With and Without Digital Assistance
The primary objective of this study is to compare the postoperative visual acuity curves of patients that underwent one of the following surgical procedures: Insertion of an extended depth of focus intraocular lens with digital…
- Conditions
- Presbyopia, Pseudophakia, Cataract, Refractive Errors
- Trial name
- NCT06460389
- Testing
- Visual Acuity Assessment
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Posterior Chamber Phakic Intraocular Lens, Vault
Study on the Diagnostic Efficacy of ICL Selection and Prediction Depth Model Based on Eye Images
To evaluate the diagnostic efficacy of deep learning network model in implantable collamer lens selection and prediction in a multicenter cross-sectional study
- Conditions
- Posterior Chamber Phakic Intraocular Lens, Vault, Deep Neural Network, Myopia
- Trial name
- NCT06669728
- Testing
- AI diagnostic algorithm
- Where
- China
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Nanchang University
Tilt and Decentration
Objective Assessment of Intraocular Lens Tilt and Decentration
Prospective, multi-center, non-interventional, open label, randomized clinical study.
- Trial name
- NCT07324200
- Testing
- OCT Imaging Test
- Where
- 2 sites in United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
To Collect Information About Visual Outcomes and Participant Satisfaction
Prospective Evaluation of Visual Outcomes With Tecnis One-Piece Multifocal Intraocular Lenses Compared With Patients Previously Implanted With Crystalens Aspheric Optic (AO)
The study is being conducted to collect information about visual outcomes and participant satisfaction with the Tecnis One-Piece Multifocal (MF) Intraocular Lenses (IOLs) compared with participants previously implanted with…
- Trial name
- NCT01191229
- Testing
- Tecnis one-piece MF IOL, Crystalens AO
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
Cataract, Presbyopia
Clinical Investigation of a Small Aperture Extended Depth of Focus Intraocular Lens in Patients With Complex Corneas
The objective of this study is to evaluate the clinical outcomes of the IC-8 IOL implanted in patients with complex corneas after crystalline lens removal.
- Conditions
- Cataract, Presbyopia, Irregular Astigmatism
- Trial name
- NCT05574270
- Testing
- IC-8 Intraocular Lens (IOL)
- Where
- 2 sites in Philippines, Singapore
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AcuFocus, Inc.
To Study the Influence of an Multifocal Intraocular Lens With Different Addition on Intermediate Visual Acuity
Visual Performance of New Apodized Diffractive Multifocal IOL With Addition of Plus Three
The purpose of the study is to determine whether implantation of a multifocal IOL with a modified addition at lens plane(Restor +3) results in better intermediate visual acuity with similar performance at distance and near…
- Trial name
- NCT01027533
- Testing
- Implantation of a multifocal Intraocular lens
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Visual Acuity
Post-Market Study of Alcon Intraocular Lenses
The purpose of the study is to evaluate clinical and functional performance in real-world conditions in participants who have been implanted with Acrysof IQ Vivity (Extended Vision) IOLs compared with Alcon Aspheric Monofocal…
- Trial name
- NCT05414565
- Testing
- Vivity IOL, Aspheric monofocal IOL
- Where
- Australia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Cataract, Lens Opacity
Comparison of Clinical Outcomes POD L GF vs POD F GF (PHY1707)
Prospective, randomised, controlled, single-surgeon, single-center clinical study to compare the clinical outcomes of two trifocal IOLs differing in the dominance of additional power.
- Conditions
- Cataract, Lens Opacity, Presbyopia
- Trial name
- NCT03688399
- Testing
- IOL implantation experimental, IOL implantation comparator
- Where
- Hungary
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Presbyopia, Pseudophakia
Identification of Minimum Focal Points in Vision Curve Formation
The primary objective of this study is to identify how many focal points and at which distances are necessary for reliable visual curve formation and area of the curve (AoC) calculation using mathematical models and comparing the…
- Conditions
- Presbyopia, Pseudophakia, Cataract, Refractive Errors
- Trial name
- NCT06260852
- Testing
- Diagnostic Test: Visual Acuity Assessment
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Myopia, Astigmatism
Randomized, Prospective Comparison of the Outcome of Toric Implantable Contact Lens (TICL) and Q-LASIK for the Correction of Myopia With Astigmatism
The objective is to conduct a contralateral prospective clinical study to compare the safety, efficacy, and quality of vision of the STAAR Surgical Co.
- Trial name
- NCT01088568
- Testing
- the implantation of toric implantable collamer lens, customized laser-assisted in situ keratomileusis
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Refractive Errors
Comparison of Higher Order Aberrations and Contrast Sensitivity Between Acrysof SN60AT, SN60WF and Restore Intraocular Lenses
This project involves evaluation of post operative contrast sensitivity and wavefront aberration results among patients implanted with standard monofocal lenses (Acrysof SN60AT/SN60WF) and the new presbyopic correcting multifocal…
- Trial name
- NCT00345085
- Testing
- Wavefront and Contrast Sensitivity
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Corneal Endothelial Cell Loss, Secondary Intraocular Lens
Anterior Chamber Versus Scleral Fixated Intraocular Lens: Long-term Vision and Safety Outcomes
This is a prospective comparative non-randomized cohort study to understand the long-term vision outcomes, safety, and stability of anterior chamber intraocular lenses (AC IOLs) vs. scleral-fixated intraocular lenses (SF IOLs).
- Trial name
- NCT04072978
- Testing
- Intraocular lens implantation
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Aphakia
Clinical Study of a UV-Absorbing Acrylic Posterior Chamber Intraocular Lens
The purpose of this study is to assess the safety and efficacy of the HMY Model YA-60BB Intraocular Lens (IOL) when implanted in the posterior chamber of the human eye for the optical correction of aphakia following cataract…
- Trial name
- HMY (NCT00625313)
- Testing
- HMY Model YA-60BB IOL
- Where
- United States
- Volunteers
- 617 people, healthy volunteers welcome
- Sponsor
- Hoya Surgical Optics, Inc.
Macular Holes, Epiretinal Membrane
Intraoperative OCT Guidance of Intraocular Surgery II
The overall five-year goals of the project are to develop novel technology to provide actionable new information through provision of live volumetric imaging during surgery, improving surgical practice and outcomes.
- Conditions
- Macular Holes, Epiretinal Membrane, Diabetic Retinopathy, Retinal Detachment
- Trial name
- MIOCT (NCT03713268)
- Testing
- Microscope integrated optical coherence tomography
- Where
- United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Duke University