Clinical trials: Lenses, Intraocular
Cataract
Comparative Study of Two Multifocal Intraocular Lens With Different Add Power
This study will compare cataract patients with implantation of diffractive multifocal IOL with an additional power of +2.75 diopters (Group 1) and with +3.25 diopters (Group 2).
- Trial name
- NCT02424162
- Testing
- +2.75 diopters multifocal intraocular lens, +3.25 diopters multifocal intraocular lens
- Where
- South Korea
- Volunteers
- 43 people
- Sponsor
- Yonsei University
Cataract
Evaluation Of Bilateral Tecnis Multifocal Versus ReSTOR 3D Intraocular Lenses
The purpose of this study is to compare the visual outcomes with bilateral implantation of Tecnis MF and ReSTOR intraocular lenses (IOLs) 6 months post cataract surgery.
- Trial name
- NCT01061918
- Testing
- Tecnis MF, ReSTOR
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Innovative Medical
Lenses, Intraocular, Visual Fields
Visual Field Changes in TECNIS ZCB00 Monofocal vs. TECNIS Symfony Extended Depth of Focus Intraocular Lens Implantation
Glaucoma is a leading cause of blindness worldwide. Damage to the optic nerve results in vision loss gradually. This vision loss can be detected by using visual field testing, and is a way of monitoring glaucoma progression.
- Conditions
- Lenses, Intraocular, Visual Fields, Cataract
- Trial name
- NCT03505827
- Testing
- 24-2 SITA Standard Humphrey Visual Field Test
- Where
- 2 sites in Canada
- Sponsor
- Western University, Canada
Glaucoma, Ocular Hypertension
Evaluation of the Safety, Efficacy, Dose Response of the Bimatoprost Drug Ring System (BIM-DRS) in Pseudophakic Patients Diagnosed With Open Angle Glaucoma or Ocular Hypertension
The goal of this clinical trial is to learn if two different doses of the SpyGlass Bimatoprost-Drug Ring System (BIM-DRS) work to treat adult pseudophakic patients with either glaucoma or ocular hypertension.
- Trial name
- NCT07641296
- Testing
- BIM-DRS Low Dose, BIM-DRS High Dose, SpyGlass IOL with silicone pads (no drug)
- Volunteers
- 24 people
- Sponsor
- SpyGlass Pharma, Inc.
Cataracts
Contralateral ReSTOR / Monofocal or Phakic Eye
Bilateral evaluation of unilateral implantation of ReSTOR and contralateral monofocal or phakic eye.
- Trial name
- NCT00731640
- Testing
- ReSTOR
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Alcon Research
Cataract
Evaluating Patient Satisfaction After Cataract Surgery With Multifocal Intraocular Lens
Multifocal lens allow most patients to be spectacle-free after cataract surgery. Most studies published up-to-date have focused on visual acuity, but not on patient-reported outcomes.
- Trial name
- NCT03787576
- Testing
- Cataract surgery
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Clínica Rementería
Cataract, Keratoconic Subjects
Visual Outcomes and Quality of Life After Vivity EDOF IOL Implantation in Early-Stage Keratoconus
The goal of this clinical trial is to learn if the Vivity Extended Depth of Focus intraocular lens works to improve vision in adults with cataracts and early-stage keratoconus.
- Trial name
- VIVITY-KCONUS (NCT07338708)
- Testing
- Extended Depth of Focus Intraocular Lens Implantation
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Presbyopia
Visual Outcomes After Presbyopic Lens Exchange
Evaluation of mean preoperative and postoperative Corrected distance visual acuity (CDVA) after Refractive Lens Exchange in presbyopic patients
- Trial name
- RELAX (NCT03790592)
- Testing
- trifocal IOL
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract, Glaucoma
IOP Changes Associated With SICS and Phako
Prospective randomized trial in patients requiring cataract surgery in which IOP, angle anatomy and other demographic and clinical data are compared. Subjects randomized to both MSICS and phakoemulsification
- Trial name
- NCT02642211
- Testing
- cataract surgery
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Robin, Alan L., M.D.
Visual Acuity
Comparative Study of Photopic and Mesopic Distance, Intermediate and Near Visual Acuity, and Spectacle Independence
The purpose of this study is to evaluate visual acuity in different lighting conditions (daylight and night time) and distances (distance, near and intermediate), and the independence of glasses, in patients who have had…
- Trial name
- NCT01191502
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
Dry Eye Disease, Cataract Surgery
Pre-Surgical Ocular Surface Treatment With Intracanalicular Dexamethasone Insert And Effect On Intraocular Lens Measurement Accuracy
This prospective study will use a self controlled design for 35 eyes. Patients scheduled to undergo routine cataract surgery in at least one of their eyes will have their pre-surgical measurements performed, IOL calculated and…
- Conditions
- Dry Eye Disease, Cataract Surgery, Ocular Surface Disease
- Trial name
- NCT04530864
- Testing
- Dextenza 0.4Mg Ophthalmic Insert
- Volunteers
- 35 people
- Sponsor
- Prism Vision Group
Cataracts
AcrySof® IQ ReSTOR® +2.5 D Multifocal Intraocular Lens (IOL) Model SN6AD2 [SV25T0] in Japan
The purpose of this study is to evaluate safety and effectiveness of AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0] in Japanese cataract patients.
- Trial name
- NCT01605877
- Testing
- AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0]
- Where
- 2 sites in Japan
- Volunteers
- 70 people
- Sponsor
- Alcon Research
GLAUCOMA 1, OPEN ANGLE, D (Disorder), Cataract
Comparison of Visual Outcomes and Patient Satisfaction in Mild to Moderate Glaucoma Patients Undergoing Cataract Surgery With EDOF Versus Monofocal IOLs
Cataract is the leading cause of reversible vision loss, while glaucoma remains the primary cause of irreversible blindness, often impairing contrast sensitivity (CS), glare tolerance, and dark adaptation.
- Trial name
- NCT07436871
- Testing
- Cataract surgery (Monofocal intraocular lens implantation), cataract surgery (Extended depht of focus intraocular lens implantation)
- Volunteers
- 74 people
- Sponsor
- OMIQ Research
Cataracts, Cataract Surgery
Endothelial Cell Loss and Induced Astigmatism After Wound-directed and Wound-assisted IOL Injection
The purpose of this study is to determine if there is any difference in astigmatism (eye surface curvature) or corneal endothelial cell density (the inner cell lining of the eye surface) after two different methods for inserting…
- Trial name
- NCT01250964
- Testing
- Lens insertion during cataract surgery
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of North Carolina, Chapel Hill
Cataract
Clinical Evaluation of a New Aspheric Intraocular Lens.
This study evaluates the visual performance and occurrence of posterior capsular opacification after implantation of a new aspherical intraocular lens compared with a control spherical lens of otherwise identical design.
- Trial name
- NCT00786565
- Testing
- Advanced Akreos Adapt in one operated eye., Akreos Adapt in fellow operated eye.
- Volunteers
- 75 people
- Sponsor
- Bausch & Lomb Incorporated
Lens Subluxation
Sutureless Technique for Repositioning and Scleral Fixation of the Capsular Bag - Intraocular Lens Complex With Permanent Use of Iris Retractors
Sutureless technique for repositioning and scleral fixation of the capsular bag-intraocular lens complex with permanent use of iris retractors
- Trial name
- NCT07257172
- Testing
- Sutureless technique for repositioning and scleral fixation of the capsular bag - intraocular lens complex with permanent use of iris retractors
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Military Institute od Medicine National Research Institute
Cataract
Evaluation of the BunnyLens TR Intraocular Lens
With age, a human crystalline lens opacifies (cataract) disabling the eye in generating a clear, well contrasted image. The only therapeutic solution to this problem is surgical replacement of the crystalline lens with an…
- Trial name
- NCT01659801
- Testing
- BunnyLens TR
- Volunteers
- 25 people
- Sponsor
- Hanita Lenses
Tilt and Decentration
Comparison of Methods for Assessing Intraocular Lens Position
Prospective, multi-center, non-interventional, open label, clinical study.
- Trial name
- NCT07218419
- Testing
- IOL Decentration Assessment
- Where
- 2 sites in United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Refractive Error Correction
Clinical Outcomes of the Use of a Femtosecond Laser on an Implanted Intraocular Lens
This is a prospective non-randomized patient controlled single center study which is designed to evaluate the clinical outcomes of the treatment of an implanted intraocular lens using a low-energy femtosecond laser for refractive…
- Trial name
- NCT07473557
- Testing
- Device
- Where
- Panama
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Perfect Lens, LLC
Cataract Congenital
Multifocal vs Monofocal IOL in Congenital Cataract Surgery
The aim of this study is to evaluate long-term outcome after congenital cataract surgery comparing results achieved with multifocal and monofocal IOLs.
- Trial name
- NCT04872829
- Testing
- cataract surgery
- Volunteers
- 43 people
- Sponsor
- Bambino Gesù Hospital and Research Institute