Clinical trials: Lenses
Myopia
Performance Comparison Between Comfilcon A and Senofilcon C Lenses
The aim of this study is to determine the clinical performance of comfilcon A in comparison to senofilcon C.
- Trial name
- NCT02920957
- Testing
- comfilcon A, senofilcon C
- Where
- 5 sites in United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Aphakia
Clinical Evaluation of the FluidVision Accommodating Intraocular Lens (AIOL)
The purpose of this study is to evaluate the safety and effectiveness of an investigational IOL.
- Trial name
- NCT02049567
- Testing
- FluidVision AIOL, Cataract Surgery
- Where
- 8 sites in Germany, South Africa
- Volunteers
- 170 people
- Sponsor
- PowerVision
Refractive Error
Formula Identification (FID) 114657 in Contact Lens Wearers
The purpose of this study is to evaluate the thickness of the pre-lens tear lipid layer after 2 hours of lens wear with use of FID 114657 compared to saline control.
- Trial name
- NCT02293538
- Testing
- FID 114657 eye drops (10 ml), Saline control eye drops (15 ml), Habitual contact lenses
- Volunteers
- 234 people
- Sponsor
- Alcon Research
Myopia
A Clinical Comparison of Two Daily Disposable Contact Lenses.
The objective of this study is to evaluate the clinical performance of two daily disposable contact lenses.
- Trial name
- NCT00775021
- Testing
- etafilcon A, nelfilcon A
- Where
- United Kingdom
- Volunteers
- 123 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Astigmatism
The Clinical Study of Silicone Hydrogel Daily Disposable Stenfilcon A Toric Lens
The aim of this study is to evaluate the clinical performance of stenfilcon A toric lenses compared with etafilcon A toric lenses for astigmatism.
- Trial name
- NCT02801006
- Testing
- stenfilcon A, etafilcon A
- Where
- 2 sites in Japan
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia, Cornea
Euclid Phoenix Lens Design Trial
The "first fit" success rate of the current Euclid orthokeratology "MAX" lens design will be compared to that of the new Euclid orthokeratology MAX "Phoenix" lens design in 30 children.
- Trial name
- NCT06389916
- Testing
- Euclid orthokeratology MAX (current design), Euclid orthokeratology MAX Phoenix (new design)
- Where
- 5 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Euclid Systems Corporation
Cataract, Aphakia
Clareon Toric vs Eyhance Toric
The primary purpose of this study is to compare the Clareon/Clareon Toric Intraocular Lenses (IOLs) to the Eyhance/Eyhance Toric IOLs in binocular Best Corrected Distance Visual Acuity (BCDVA) at 3 months postoperative.
- Trial name
- NCT05481125
- Testing
- Clareon IOL, Clareon Toric IOL, Eyhance IOL
- Where
- 8 sites in United States
- Volunteers
- 203 people
- Sponsor
- Alcon Research
Visual Acuity
Comparison of a Silicone Hydrogel Daily Disposable Multifocal Contact Lens to a Marketed Product
This is a single-masked, 2×3 crossover, randomized-controlled, dispensing clinical trial to evaluate overall quality of vision.
- Trial name
- NCT05258149
- Testing
- JJVC Investigational Multifocal Contact Lenses, Dailies Total 1® Multifocal Contact Lenses
- Where
- 12 sites in United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract
Clinical Investigation of OMEGA Gemini Capsule, Model Gemini IV With an Approved Monofocal or Toric IOL
This study is a prospective, randomized, controlled, paired eye, subject-masked design.
- Trial name
- NCT04058314
- Testing
- Gemini IV, Control Eye
- Where
- Costa Rica
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Omega Ophthalmics
Myopia
LSH Silicone Hydrogel Soft Hydrophilic Contact Lens for Daily Wear
This study is to evaluate the performance of the LSH (mangofilcon A) silicone hydrogel soft contact lenses when used as a daily wear contact lens for the correction of myopia.
- Trial name
- NCT01735045
- Testing
- Lagado LSH (mangofilcon A) Soft (hydrophilic) Contact Lens, Benz 3GX (hioxifilcon B) Soft (hydrophilic) Contact Lens
- Where
- 5 sites in United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Szabocsik and Associates, Inc.
Cataract, Presbyopia
Non-comparative Study to Assess the Visual Performances and Safety of a Progressive Multifocal Intraocular Lens
This is an interventional, non-controlled, multicenter international trial with a prospective design on one cohort of patients.
- Trial name
- PSM15 (NCT02838004)
- Testing
- IOL MINI WELL READY
- Where
- Germany
- Volunteers
- 77 people
- Sponsor
- SIFI SpA
Contact Lens Discomfort
Safety, Tolerability and Pharmacodynamics of AZR-MD-001 in Contact Lens Discomfort (CLD)
A two stage, multi-center, vehicle-controlled study to determine common symptoms in patients with Contact Lens Discomfort (CLD) in Stage 1 and to evaluate the safety, tolerability, and pharmacodynamics of AZR-MD-001 in Stage 2.
- Trial name
- NCT05548491
- Testing
- AZR-MD-001 ointment/semi-solid drug
- Where
- 2 sites in Australia
- Volunteers
- 67 people
- Sponsor
- Azura Ophthalmics
Lymphoma
Revlimid® Capsules Drug Use-results Surveillance (Relapsed or Refractory ATLL)
To understand the safety and efficacy of Revlimid® Capsules 2.5 mg and 5 mg (hereinafter referred to as Revlimid) under actual conditions of use in patients with relapsed or refractory adult T-cell leukemia lymphoma (hereinafter…
- Trial name
- NCT03098589
- Testing
- Revlimid
- Where
- Japan
- Volunteers
- 1,149 people
- Sponsor
- Celgene
Visual Acuity
Contact Lens Insertion and Removal in a Senior Subject Demographic
This will be a pilot, one-visit, open-label, non-dispensing study. Subjects will be given instructions and then attempt to insert and remove a contact lens in each eye.
- Trial name
- NCT03597178
- Testing
- senofilcon A
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Error
Lens Wearing Experience and Biocompatibility of a Marketed Multi-Purpose Disinfecting Solution in Silicone Hydrogel and Soft Contact Lens Wearers
The purpose of this study was to describe mean differences in corneal staining (type and area) for OPTI-FREE PureMoist Multi-Purpose Disinfecting Solution (MPDS) at Day 30 compared to Baseline (Day 0).
- Trial name
- NCT01484938
- Testing
- OPTI-FREE PureMoist
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- Alcon Research
Cataract, Inflammation
Mapracorat Ophthalmic Suspension, 3% for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery
The objective of this clinical study is to compare the safety and efficacy of mapracorat ophthalmic suspension, 3% with its vehicle for the treatment of postoperative inflammation and pain following cataract surgery.
- Conditions
- Cataract, Inflammation, Surgery
- Trial name
- NCT01591655
- Testing
- Mapracorat, Vehicle
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- Bausch & Lomb Incorporated
Cataracts
VIGADEXA Gel Compared to VIGADEXA Solution Following Cataract Surgery
The purpose of this study is to compare VIGADEXA (moxifloxacin 0.5%/dexamethasone phosphate 0.075%) ophthalmic gel to VIGADEXA (moxifloxacin 0.5%/dexamethasone phosphate 0.1%) ophthalmic solution in the prevention of…
- Trial name
- NCT01515826
- Testing
- Moxifloxacin 0.5%/Dexamethasone Phosphate 0.075% Ophthalmic Gel (VIGADEXA Gel), Moxifloxacin 0.5%/Dexamethasone Phosphate 0.1% Ophthalmic Solution (VIGADEXA Solution)
- Sponsor
- Alcon Research
Refractive Ametropia, Myopia
Comparison of Two Daily Disposable Lenses
The purpose of this study was to compare the clinical performance of the new DAILIES® AquaComfort PLUS® FreshTech (DACP FreshTech) contact lenses to an already marketed daily disposable contact lens, DAILIES® AquaComfort PLUS®…
- Trial name
- NCT04013789
- Testing
- DACP FreshTech contact lenses, DACP contact lenses
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Alcon Research
Visual Acuity
Evaluation of Toric Soft Contact Lenses Containing a Chromophore to Block High-Energy Visible Light
This will be a 4-visit, randomized, controlled, single-masked, bilateral wear, dispensing, 2-treament, 2-sequence, 3-period crossover study to evalulate overall vision and comfort..
- Trial name
- NCT05344560
- Testing
- soft contact lens in senofilcon A (C3) with HEVL-blocking chromophore, ACUVUE OASYS 1-Day for Astigmatism
- Where
- 10 sites in United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Clinical Evaluation of Daily Disposable Contact Lenses
The objective of the study is to compare the overall subjective preference of filcon II 3 daily disposable silicone hyrogel contact lenses compared to etafilcon A and nelfilcon A daily disposable conventional hydrogel contact…
- Trial name
- NCT02097030
- Testing
- filcon II 3, etafilcon A, nelfilcon A
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- CooperVision, Inc.
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