Clinical trials: Lenses
Cataract
Evaluation of the Eyhance and Zoe Lenses
The goal of this observational study is to assess distance and near visual acuity of patients who have undergone cataract surgery with two intraocular lenses (IOLs).
- Trial name
- NCT06665659
- Volunteers
- 50 people
- Sponsor
- University Hospital Plymouth NHS Trust
Cataract, Astigmatism
Astigmatism Correction With Intrastromal Arcuate Incisions in Eyes Undergoing Cataract Surgery With Femtosecond Laser Using the Cassini Ambient With Iris Registration (ARCUATAS)
This is an observational, prospective follow-up post-marketing study of CE marked medical devices aimed at treating astigmatism in patients with cataracts.
- Trial name
- ARCUATAS (NCT05053620)
- Testing
- Calculation of the arcuate intrasomal incisions
- Where
- Spain
- Volunteers
- 22 people
- Sponsor
- OFTALVIST (Oftalmología Vistahermosa S.L)
Cataract, Lens Opacities
A Comparison of FineVision Intraocular Lenses vs Symfony Intraocular Lenses
This is a prospective randomised open-label study with the aim to compare the visual performance of the trifocal FineVision® IOL versus the extended range of vision Symfony® IOL after phaco-emulsification cataract surgery.
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- NCT03974451
- Testing
- IOL implantation experimental, IOL implantation active comparator
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataract
Quality Assurance Via Telephone Interviews After Cataract Surgery
To analyse quality assurance after cataract surgery by assessing discomfort and other symptoms via telephone interviews either in the evening of the day of the surgery or 1 day after surgery versus no additional call after…
- Trial name
- NCT05215002
- Testing
- Telephone Call, No telephone call
- Where
- Austria
- Volunteers
- 200 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Cataract
Reading Performance in Patients With Acrysof IQ Vivity Versus Acrysof IQ
Comparison of the visual function and reading performance between the Acrysof IQ Vivity IOL, an EDOF IOL, and the monofocal Acrysof IQ.
- Trial name
- NCT05194657
- Testing
- enhanced depth of focus IOL, monofocal IOL
- Where
- Austria
- Volunteers
- 68 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Zonule of Zinn Abnormality, Zonular Cataract
Repeatability and Reproducibility of Lens Zonule Length Measurement Using ArcScan Insight 100
The purpose of this study is to evaluate the intra-examiner repeatability and inter-examiner reproducibility in lens zonule length measurements using very high-frequency (VHF) digital ultrasound (ArcScan Insight 100).
- Trial name
- NCT05657951
- Testing
- ArcScan Insight 100 very high-frequency digital ultrasound
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Cataract
Visual Outcomes of Subjects Bilaterally Implanted With ReSTOR Aspheric +4 vs. Tecnis or Acri.LISA
This is a study to compare visual outcomes of subjects bilaterally implanted w/ReSTOR to subjects bilaterally implanted with the Tecnis Multifocal Intraocular Lens (IOL) or Acri.LISA IOL
- Trial name
- NCT00721253
- Testing
- ReSTOR, Tecnis, Acri.LISA
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Cataract
Feasibility of an Artificial Intelligence Phone Call After Cataract Surgery
To analyze the evidence for clinical safety, usability, acceptability, satisfaction, appropriateness, and cost-effectiveness of Dora for recognizing patients who require additional in-person evaluation post cataract surgery.
- Trial name
- NCT05766722
- Testing
- DORA AI
- Volunteers
- 250 people
- Sponsor
- Uptown Eye Specialists
Myopia
Evaluation of Daily Disposable Lenses With Multi-Purpose Solution (MPS)
The purpose of this study is to evaluate daily disposable lenses inserted out of the blister package versus daily disposable lenses inserted after a pre-soak in Multi-purpose solution FID 107027.
- Trial name
- NCT00733291
- Testing
- Nelfilcon A contact lens, Etafilcon A contact lens, FID 107027 solution
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Alcon Research
Cataracts
Comparing Optical Coherence Tomography (OCT) and Visual Acuity Outcomes in Subjects Undergoing Cataract Surgery, Who Receive Xibrom Ophthalmic Solution and Standard Presurgical Care vs. Xibrom Ophthalmic Solution Plus Prednisolone Acetate 1% and Standard Presurgical Care
To compare the efficacy of twice-daily topical bromfenac (Xibrom) ophthalmic solution alone versus twice-daily topical Xibrom with prednisolone acetate 1% three-times daily on visual acuity and OCT measurements.
- Trial name
- NCT00698724
- Testing
- Xibrom, and Optive, Xibrom and Pred Forte
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bp Consulting, Inc
Cataract Senile
Study on Visual Performance of a Monofocal Intraocular Lens
Retrospective/Prospective Study on Visual Performance of a Monofocal Intraocular Lens (IOL). The objective is to compare best corrected distance visual acuity (CDVA) between 1-3-month and 12- month follow-up.
- Trial name
- NCT04740788
- Testing
- Monofocal IOL
- Where
- Austria
- Volunteers
- 44 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract, Vitreous Hemorrhage
Surgical Procedure Efficiency Evaluation stuDy
The purpose of this real-world evidence study is to compare surgical procedure times for UNITY® VCS and CONSTELLATION® Vision System.
- Conditions
- Cataract, Vitreous Hemorrhage, Retinal Detachment, Macular Pucker
- Trial name
- NCT07228091
- Testing
- UNITY VCS, CONSTELLATION
- Where
- United Kingdom
- Volunteers
- 180 people
- Sponsor
- Alcon Research
Visual Acuity
Evaluation of Daily Disposable Silicone Hydrogel Multifocal Toric Contact Lenses
The study is a bilateral, single-masked, single-arm, 4-visit dispensing study. There will be one study treatment, with the subject being dispensed lenses for 6 to 8 days, then lens power will be optimized (if necessary) and…
- Trial name
- NCT04974697
- Testing
- JJVC Investigational Multifocal Toric Contact Lens
- Where
- 8 sites in United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract, Glaucoma
The Effects of a Large Language Model on Clinical Questioning Skills
The researchers have used the ophthalmology textbook, clinical guideline consensus, the Internet conversation data and knowledge base of Zhongshan Ophthalmology Center in the early stage, combined with artificial feedback…
- Conditions
- Cataract, Glaucoma, Diabetic Retinopathy, Keratitis
- Trial name
- NCT06229379
- Testing
- "Digital twin patient", Interaction with real patients
- Where
- China
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Myopia
Study Intended to Evaluate the Safety and Effectiveness of a Johnson & Johnson Vision Care Inc, (JJVCI) Contact Lens for Use on an Extended-wear Basis for up to 7 Days (6 Nights).
Study in the US intended to evaluate the safety and effectiveness of a Johnson \& Johnson Vision Care Inc, (JJVCI) contact lens for use on an extended-wear basis for up to 7 days (6 nights).
- Trial name
- NCT00241280
- Testing
- etafilcon A, galyfilcon A
- Where
- 25 sites in United States
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Myopia Control With the Multi-segment Lens
The purpose of this study is to determine if the Multiple-Segment (MS) spectacle lens can slow myopia progression in Hong Kong schoolchildren. MS lens is also called Defocus Incorporated Multiple Segments (DIMS) spectacle lens
- Trial name
- NCT02206217
- Testing
- Multiple-Segment spectacle lens
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Glaucoma, Angle-Closure
Implantation of Capsular Tension Ring in Primary Angle Closure Patients With Zonular Laxity or Dialysis
Primary angle closure glaucoma (PACG) is the main type of glaucoma in China, which includes acute and chronic PACG. According to the International Society of Geographical and Epidemiological Ophthalmology (ISGEO), this spectrum…
- Trial name
- NCT05542290
- Testing
- Capsular tension ring implantation, No capsular tension ring implantation
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Beijing Tongren Hospital
Cataract
Occyo Tele-ophthalmology Study
The prospective, (observer) blinded clinical trial at the University Hospital for Ophthalmology includes patients routinely scheduled for cataract surgery at the Medical University of Innsbruck.
- Trial name
- OTS (NCT06681350)
- Testing
- Ocular surface imaging
- Where
- Austria
- Volunteers
- 365 people
- Sponsor
- Medical University Innsbruck
Cataract, Corneal Astigmatism
Clinical Trial of a Hydrophilic EMV Toric Lens RAO210T in the Correction of Aphakia and Corneal Astigmatism
The objectives of the clinical investigation are to determine the safety and performance of the RayOne EMV Toric (Model RAO210T) following unilateral implantation and approximately 6 months (120 to 180 days) of post-operative…
- Trial name
- NCT05985304
- Testing
- RayOne EMV Toric IOL, RayOne Monofocal IOL, Cataract Surgery
- Where
- 9 sites in United States
- Volunteers
- 274 people
- Sponsor
- Rayner Intraocular Lenses Limited
Cataract
Three Intraocular Lenses Designed to Improve Distance, Intermediate and Near Vision Following Lens Extraction
The objective of this study is to compare the contrast sensitivity, high and low contrast visual acuity (VA), glare meter outcomes, and subject satisfaction with three different FDA-approved intraocular lenses (IOLs) designed to…
- Trial name
- NCT01225952
- Testing
- Crystalens AO, ReSTOR 3.0, AMO Tecnis Multifocal
- Where
- Philippines
- Volunteers
- 93 people
- Sponsor
- Bausch & Lomb Incorporated
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