Clinical trials: Lenses
Dry Eye Disease (DED), Cataract
Rebamipide Versus Diquafosol and Cyclosporine for Perioperative Dry Eye in Cataract Surgery
The goal of this clinical trial is to compare the efficacy of 2% rebamipide monotherapy versus a combination therapy of 3% diquafosol and 0.05% cyclosporine for the management of dry eye disease in patients undergoing cataract…
- Trial name
- NCT07397936
- Testing
- Rebamipide 2% ophthalmic solution, Diquafosol 3% ophthalmic solution, Cyclosporine 0.05% ophthalmic solution
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Samsung Medical Center
Presbyopia
Extended Depth of Focus Contact Lenses for Presbyopia
VTI has an FDA cleared soft contact lens product. Its optical design creates an enhanced depth of focus (EDOF), which provides clear distance, intermediate, and near vision.
- Trial name
- NCT05495971
- Testing
- NaturalVue Multifocal
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Visioneering Technologies, Inc
Astigmatism
Clinical Performance of a Daily Disposable Toric Silicone Hydrogel Contact Lens
The purpose of this study is to obtain on-eye clinical performance data to evaluate the stability of axis orientation of DDT2 toric contact lenses in the intended population.
- Trial name
- NCT04464044
- Testing
- verofilcon A toric contact lenses
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Alcon Research
Astigmatism
A Bilateral Dispensing Clinical Trial of an Sapphire Lens Against Senofilcon A Toric for Astigmatism Lens
This study was conducted to evaluate the clinical performance of an investigational silicone-hydrogel lens against Senofilcon A toric lens. The study results were not used for design validation of the investigational product.
- Trial name
- NCT02555098
- Testing
- Sapphire contact lenses, senofilcon A contact lenses
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- CooperVision, Inc.
Cataract
Visual Function After Implantation of Bilateral AcrySof® Toric Natural Intraocular Lens
The purpose of this study is to evaluate the effect that placement and power of the AcrySof Toric has on post-operative visual acuity and spectacle independence for distance vision.
- Trial name
- NCT00760487
- Testing
- AcrySof Toric IOL
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Alcon Research
Cataract Surgery, Patient Satisfaction
Evaluation of Duration of Anesthesia and Patient Satisfaction After Retrobulbar Block Applied in Cataract Surgery
It is aimed to determine patient satisfaction (pain assessment during and after the operation) and the initial and total anesthesia durations of eye lid and globe anesthesia after administration of local anesthetic solution only…
- Conditions
- Cataract Surgery, Patient Satisfaction, Akinesia, Anesthesia, Local
- Trial name
- NCT04178200
- Testing
- Lidocaine 2% Injectable Solution 0.75 ml, Bupivacaine Hcl 0.5% Inj 0.75 ml, Lidocaine 2% Injectable Solution 1.5 ml
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Develi Devlet Hastanesi
Visual Acuity
Clinical Evaluation of Daily Disposable Etafilcon A Cosmetic Contact Lenses
This will be a randomized, double-masked, bilateral, cross-over, 2 treatment by 2 period dispensing study. There will be 4 visits. There will be a 2 to 5 day washout period between treatments.
- Trial name
- NCT04529109
- Testing
- etafilcon A investigational cosmetic lens 1, etafilcon A investigational cosmetic lens 2
- Where
- 4 sites in United States, Hong Kong
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Contact Lens, Questionnaire
Chinese Translation and Validation of the 8-item Contact Lens Dry Eye Questionnaire (CLDEQ-8)
This is a cross-cultural adaptation, evaluation and validation study of the 8-item Contact Lens Dry Eye Questionnaire (CLDEQ-8) among soft contact lens wearers in China.
- Conditions
- Contact Lens, Questionnaire, Contact Lens Discomfort
- Trial name
- CLDEQ-8 (NCT05416528)
- Where
- China
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Diabetic Retinopathy
The Effect of Intravitral Injection of Triamcinolone Combined With Cataract Surgery (Phacoemulsification) on Diabetic Macular Edema and Diabetic Retinopathy
In this study, regressed proliferative diabetic retinopathy, very severe, severe and moderate non-prolifrative diabetic retinopathy patients who were going to have a cataract surgery, underwent a complete eye examination, OCT…
- Trial name
- NCT00849537
- Testing
- Triamcinolone
- Where
- 3 sites in Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
Presbyopia, Refractive Error
Dispensing Study to Assess the Visual Performance of Optimised Prototype Contact Lenses
The aim of this study is to assess the visual performance of multiple optimised prototype soft contact lens designs compared to commercially available contact lenses.
- Trial name
- NCT02484586
- Testing
- Etafilcon A, Nelfilcon A, Nesofilcon A
- Where
- Australia
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Brien Holden Vision
Cataract
Dynamic Light Scattering for Studying Lens Aging and Cataract Formation
This study will use dynamic light scattering (DLS) technology to study normal lens aging and early cataract formation. Cataract is a clouding of the lens that interferes with the passage of light to the retina, impairing visual…
- Trial name
- NCT00081991
- Where
- United States
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Cataract Surgery, Glaucoma Surgery
PREFERENTIAL Study
To determine patient preference for the dexamethasone insert or topical prednisolone therapy through at Day 45 as measured by - Modified COMTOL survey.
- Trial name
- NCT04563559
- Testing
- Dextenza 0.4Mg Ophthalmic Insert, Prednisolone Acetate 1% Ophthalmic Suspension [PRED FORTE]
- Sponsor
- Duke University
Refractive Error, Cataract
Improving Vision and Quality of Life in the Nursing Home
The primary purpose of this study is to evaluate whether interventions to improve vision in nursing home residents have an impact on residents' health-related quality of life.
- Trial name
- NCT00347620
- Testing
- spectacles, Cataract Surgery
- Where
- 17 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Fuchs' Endothelial Dystrophy, Cataract
The Effects of Ripasudil in Patients With FED Undergoing Femtosecond Laser Assisted Cataract Surgery
The purpose of this research is to investigate the effects of ripasudil administered as an ophthalmic solution in patients with FED after femtosecond laser assisted cataract surgery.
- Trial name
- NCT06048380
- Testing
- Ripasudil
- Where
- Singapore
- Volunteers
- 120 people
- Sponsor
- Singapore Eye Research Institute
Visual Acuity
Evaluation of Prototype Lenses With Experimental UV/HEV Blocker
This is a bilateral, 2-week dispensing, randomized, controlled, subject-masked, 2×2 crossover study to evaluate the clinical performance of prototype contact lenses with experimental UV/HEV-blocker.
- Trial name
- NCT04885296
- Testing
- TRP-200, JJVC Marketed Contact Lens
- Where
- 12 sites in United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract; Eye Disease
The Utility of a Novel Eye Shield With Reusable Adhesive Anchors for Post-operative Care After Ophthalmic Surgery
The purpose of this research study is to evaluate the efficacy, patient preference, and utility of a novel eye shield that utilizes a different adhesive mechanism in comparison to the current standard of care.
- Trial name
- NCT05957796
- Testing
- Novel "Snaps" Eye Shield, Standard Alcon Eye Shield
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Augusta University
Cataract
Study of Efficacy and Safety of Vigadexa in Treating Inflammation and Infection Post-cataract Surgery
To demonstrate that the combination formulation of Moxifloxacin/Dexamethasone Eye Drop is effective and safe for the prevention of postoperative inflammation as a consequence of cataract extraction surgery.
- Trial name
- NCT00870103
- Testing
- Vigadexa (moxifloxacin 0.5% and dexamethasone 0.1%) eye drops
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Alcon Research
Myopia
Study of Safety and Effectiveness of the Boston Orthokeratology Shaping Lens in the Arise Orthokeratology Lens
The objective of this orthokeratology study is to evaluate the safety and effectiveness of the Arise Orthokeratology Lens with non-spherical posterior peripheral curves
- Trial name
- NCT05984290
- Testing
- orthokeratology lens
- Where
- 6 sites in United States
- Volunteers
- 90 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract
A Clinical Study of Tobradex AF
The purpose of this study is to determine the amount of study medication that moves from the front of the eye into the fluid at the front of the inside of the eye.
- Trial name
- NCT00473070
- Testing
- Tobradex AF
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- Alcon Research
Salt Hypertension From Excess Dietary Salt, Lens Opacities
Salt Sensitivity Hypertension and Lens Opacities
Salt-sensitive hypertension (SSH) accounts for about the half of all Hypertension (HT) cases .In SSH, Na+/K+-ATPase activity is impaired.
- Trial name
- NCT03385070
- Testing
- Lens examination
- Where
- Turkey (Türkiye)
- Volunteers
- 429 people, healthy volunteers welcome
- Sponsor
- Kecioren Education and Training Hospital
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