Clinical trials: Lenses
Cataract
EYEFILL® C. -US Viscoelastic Clinical Investigation
The purpose of this multicenter, prospective, randomized clinical study is to determine the safety and effectiveness of the EYEFILL® C.-US Viscoelastic in patients undergoing cataract extraction and intraocular lens (IOL)…
- Trial name
- NCT02024711
- Testing
- EYEFILL® C.-US Viscoelastic, Healon® Viscoelastic (CONTROL)
- Where
- 8 sites in United States
- Volunteers
- 262 people
- Sponsor
- Bausch Health Americas, Inc.
Cataracts
A Clinical Outcome Study of Two Multifocal Intraocular Lenses (IOL) in Cataract Patients
The purpose of this study is to compare AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL in both eyes (bilateral implantation) to AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL in the dominant eye with AcrySof® IQ ReSTOR® +3.0 D Multifocal…
- Trial name
- NCT01684007
- Testing
- AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0], AcrySof® IQ ReSTOR® +3.0 D Multifocal IOL Model SN6AD1
- Volunteers
- 112 people
- Sponsor
- Alcon Research
Refractive Error - Myopia Simple
Evaluation of the Safety and Efficacy of PEGAVISION Silicone Hydrogel Daily Disposable Soft Contact Lenses (G3)
The goal of this clinical trial is to learn if PEGAVISION Silicone Hydrogel Daily Disposable Soft Contact Lenses (G3) are safe and effective for vision correction in adults.
- Trial name
- NCT06995781
- Testing
- Experimental Intervention, Active Comparator Intervention
- Volunteers
- 69 people
- Sponsor
- Pegavision Corporation
Myopia
Two Daily Disposable Contact Lenses in Symptomatic Patients
The purpose of this study is to evaluate the performance of DAILIES TOTAL1® and ACUVUE OASYS® 1-DAY and with respect to visual acuity in a symptomatic study population of monthly or bi-weekly replacement lens wearers.
- Trial name
- NCT03628599
- Testing
- Delefilcon A contact lenses, Senofilcon A contact lenses
- Where
- 4 sites in United States
- Volunteers
- 39 people
- Sponsor
- Alcon Research
Cataract Extraction, Fasting
Preoperative Fasting for Ambulatory Cataract Surgery: The PRACTICE Study
The current standard for cataract surgery is phacoemulsification with intraocular lens (IOL) implantation. In this procedure, topical anesthesia has become favoured over local anesthetic blocks due to potential serious…
- Conditions
- Cataract Extraction, Fasting, Aspiration Pneumonitis
- Trial name
- PRACTICE (NCT03828500)
- Testing
- Assistant-encouraged fasting up to ASA/CAS guideline limits
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University of Toronto
Refractive Errors, Cataract
Xinxing Eye Cohort Study
To establish the baseline levels and monitor the progress of two newly introduced global eye health indicators in Xinxing County, including effective refractive error coverage (eREC) and effective cataract surgery coverage…
- Trial name
- NCT07257536
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Cataract, Surgical Injury
Eye Surface Properties After Using Dexamethasone Drops With and Without Preservatives in Patients After Cataract Surgery
The goal of this interventional, real world data study is to evaluate the impact of preservatives on the post-cataract ocular surface. The main question is to learn about an effect of preservatives on the eye surface.
- Conditions
- Cataract, Surgical Injury, Healing Wound
- Trial name
- EyeSurface (NCT05753787)
- Testing
- preservative-free solution of standard post-cataract eye drops
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Spektrum Center of Clinical Ophthalmology
Myopia
Evaluation of Etafilcon A Daily Disposable Lenses
To evaluate the clinical performance of daily disposable etafilcon A lenses.
- Trial name
- NCT02061592
- Testing
- etafilcon A
- Where
- 7 sites in United States
- Volunteers
- 136 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
SEED-LVPEI Myopia Study
This randomized clinical trial study aims to investigate the efficacy of novel SEED's EDOF based mid-lens design in controlling the myopia progression in Indian children with these specific objectives: 1.
- Trial name
- SLIMS (NCT04618510)
- Testing
- SEED 1-dayPure EDOF soft contact lens, Single Vision Spectacles
- Where
- India
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- L.V. Prasad Eye Institute
Dry Eye
Single-Arm Study of a Treatment for Dry Eye in People Who Struggle to Wear Contact Lenses
This research study is to see if using Lacrifill is safe, easy to use, and helpful for people who wear contact lenses but can't wear them comfortably for long.
- Trial name
- NCT07510620
- Testing
- Lacrifill
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vision Innovation Centers of Pennsylvania, LLC d/b/a Eye Care Specialists
Cataract
Level of Agreement of Intraocular Lens Power Measurements Between IOLMaster and Verion
Primary objective of this study is to evaluate the level of agreement of two keratometry modules, the IOLMaster and the Verion Reference Unit, in terms of keratometric values and IOL power calculation.
- Trial name
- NCT03876782
- Testing
- IOLMaster, Verion
- Where
- Greece
- Volunteers
- 54 people
- Sponsor
- Democritus University of Thrace
Visual Acuity
Clinical Evaluation of Multifocal Toric Contact Lenses
This is a double-masked, bilateral, randomized, non-dispensing clinical trial. The study lenses will be worn in a bilateral and random fashion using a 5x5 crossover Williams design with 5 lens types and 5 periods.
- Trial name
- NCT03208088
- Testing
- etafilcon A Investigational Toric Multifocal Contact Lens
- Where
- 7 sites in United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Error
Evaluation of Deposits on Contact Lenses Worn Daily Wear
The purpose of this study was to measure front surface deposits on contact lenses when worn for ten hours.
- Trial name
- NCT00725153
- Testing
- Balafilcon A contact lenses (PureVision), Etafilcon A contact lenses (Acuvue2)
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Alcon Research
Cataract, Presbyopia Correction
Photopic and Mesopic Multifocal IOL Performance
Modern cataract surgery has become a refractive procedure. Both, multifocal lens implantation and pseudophakic monovision with monofocal IOLs are effective means to address presbyopia correction after cataract surgery.
- Trial name
- MIOLRead (NCT06978556)
- Testing
- No intervention is subject of the study. Only standard pre- and postoperative data will be evaluated.
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IROC AG
Myopia
Clinical Assessment of Two Daily Wear Monthly Replacement Soft Silicone Hydrogel Contact Lenses
The purpose of this study is to compare the clinical performance of TOTAL30 contact lenses with Biofinity contact lenses over 30 days of daily wear.
- Trial name
- NCT04980456
- Testing
- Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
- Where
- 14 sites in United States
- Volunteers
- 257 people
- Sponsor
- Alcon Research
Glaucoma, Cataract
Eye Drop Dispensers: Safety, Efficacy and Comfort.
One aspect to eye drop adherence is successful instillation of the drops; however, it is well known that many patients struggle with this task.
- Conditions
- Glaucoma, Cataract, Healthy Subjects
- Trial name
- NCT03417453
- Testing
- Eye Drop Dispenser TYPE Opticare, Eye Drop Dispenser Autodrop
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Ametropia, Myopia
Apioc Contact Lens Feasibility
This clinical trial will document the feasibility of the Apioc lens design by assessing which lens shape parameters yield successful on-eye-fit and movement of the Apioc contact lens design and evaluate the subjectively-reported…
- Conditions
- Ametropia, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT03688672
- Testing
- Apioc Contact Lens Design
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lentechs, LLC
Cataract
Study of Comparison Between Pentacam and locs3
Hypothesis: There is no difference between pentacam scheimpflug system and locs3 in grading of cataract. Major aims: 1. research the efficiency of pentacam scheimpflug system in lens density measurment. 2.
- Trial name
- NCT00808886
- Sponsor
- Soroka University Medical Center
Cataract
Clinical Results of Asqelio™ EDOF Toric Soft Hydrophobic Intraocular Lens After Cataract Surgery
The goal of this observational study is to assess the clinical outcomes of binocular implantation of Asqelio EDOF Toric IOLs in healthy cataract patients.
- Trial name
- NCT06229756
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- AST Products, Inc.
Astigmatism
Performance Evaluation of Two Silicone Hydrogel Toric Lens Designs in Habitual Soft Contact Lens Wearers
The objective of the study was to compare the clinical performance of two monthly toric silicone hydrogel contact lenses in habitual wearers, when worn for 1-month each.
- Trial name
- NCT05933772
- Testing
- Lens A (comfilcon A toric lens), Lens B (lehfilcon A toric lens)
- Where
- 5 sites in United States, Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CooperVision International Limited (CVIL)
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