Clinical trials: Leptin Resistance
Obesity, Leptin Resistance
Effect of Increased Free Fatty Acids on Leptin Function
Obese people have elevated levels of the hormone leptin. Despite this, they seem to be resistant to the effects of this hormone, which usually regulates appetite and energy expenditure.
- Trial name
- NCT01520454
- Testing
- Saline, Intralipid, Water
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Nonalcoholic Steatohepatitis, Metabolic Syndrome
The Role of Leptin Receptors in NASH
NAFLD is a spectrum of liver diseases associated with varying degrees of hepatic steatosis, inflammation, and in some cases, fibrosis.
- Trial name
- NASH (NCT00583999)
- Testing
- no interventions, only regular blood-draw
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
HIV Lipodystrophy
Combination of Insulin Sensitizer and Leptin as Treatment for the HAART -Induced Metabolic Syndrome
The purpose of this study is to determine whether patients with HIV lipodystrophy (fat wasting) benefit from taking the combination of two drugs, one insulin sensitizer (either metformin or pioglitazone, both diabetes drugs) and…
- Trial name
- NCT00362440
- Testing
- Leptin, Pioglitazone or metformin
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Obesity, Overweight
Whey Protein Intake With and Without Exercise on Visceral Fat: The P+RISE Study
Dietary manipulation is proving to be an effective lifestyle strategy to combat the obesity epidemic. Increased dietary protein is one effective strategy.
- Trial name
- P+RISE (NCT01960335)
- Testing
- Whey Protein, Whey Protein and Resistance Exericse, Whey Protein and RISE exercise routine
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Skidmore College
Obesity, Metabolic Syndrome
Benzoates - an Obesogenic Endocrine Disrupting Chemical
The benzoic acid derivatives sodium and potassium benzoate are preservatives that are commonly added to food and beverages to inhibit microbial growth and prevent spoilage.
- Trial name
- NCT03190785
- Testing
- Benzoic acid washout and exposure
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- East Carolina University