Clinical trials: Lesion; Duodenum
Premalignant Conditions, Malignant Lesions
To Evaluate the Best Metric for Inspection Time During a Diagnostic and/or Surveillance Upper Gastrointestinal Endoscopy (Age ≥ 18 Years, Informed Consent), Between Total Inspection Time Versus Withdrawal Time, for the Identification of Malignant Lesions
Gastric cancer is the fifth cause of cancer-related mortality worldwide. Gastric carcinogenesis involves the progression from premalignant conditions such as atrophic gastritis and intestinal metaplasia to premalignant lesions…
- Conditions
- Premalignant Conditions, Malignant Lesions, Gastric, Esophageal
- Trial name
- NCT06696209
- Testing
- Analysis of the withdrawal time of the Upper Gastrointestinal Endoscopy, Analysis of the total time of the Upper Gastrointestinal Endoscopy, Upper gastrointestinal endoscopy: Common Practices
- Where
- Portugal
- Volunteers
- 1,290 people, healthy volunteers welcome
- Sponsor
- Portuguese Oncology Institute, Coimbra
Duodenal Diseases, White Spot Lesion
İmportance of Scattered White Spots Detected in the Duodenum and Their Relationship wıth Zonulin
With our study, we aimed to determine whether there is a correlation between zonulin, which plays a crucial role in intestinal barrier function and is implicated in the etiopathogenesis of many chronic and autoimmune diseases…
- Trial name
- NCT06200129
- Testing
- sws grade 1, sws grade 2, control
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Gastric Lesion, Gastritis
Capsule Gastric Endoscopy for Gastric Disease Screening in Simulated Home Scenarios
The goal of this clinical trial is to evaluate the diagnostic accuracy of the AI-integrated Capsule Gastroscopy (ACG) system in simulated home-use conditions for detecting upper gastrointestinal (UGI) abnormalities.
- Conditions
- Gastric Lesion, Gastritis, Upper Gastrointestinal Bleeding (UGIB), Gastric Dysplasia
- Trial name
- NCT06848400
- Testing
- AI-integrated Capsule Gastroscopy (ACG) examination, Electronic gastroduodenoscopy (EGD) examination
- Where
- 12 sites in China, Hong Kong and 1 more
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Duodenal Neuroendocrine Tumor
Efficacy of Endoscopic Band Ligation (DEBL) for Duodenal Neuroendocrine Neoplasms(dNENs)
Primary objective To evaluate the therapeutic efficacy (clinical success) of dEBL at 3 months 2b. Secondary objective To evaluate adverse events, technical success and recurrence on follow-up 50 patients over 1-year duration…
- Trial name
- DEBL (NCT06790056)
- Testing
- duodenal ndoscopic bind ligation
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Esophagogastroduodenoscopy, Simethicone
Premedication With N-acetylcysteine and Simethicone to Improve Mucosal Visualization in Elective Upper Endoscopy
The goal of this randomized, double-blind, placebo-controlled clinical trial is to assess whether the combination of N-acetylcysteine and simethicone improves mucosal visibility during upper gastrointestinal endoscopy in adults…
- Conditions
- Esophagogastroduodenoscopy, Simethicone, N-Acetylcysteine, Premedication
- Trial name
- NACSIMET (NCT07245095)
- Testing
- Premedication with n-acetylcysteine, Premedication with simethicone
- Where
- 2 sites in Mexico
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Hospital General de Mexicali
Stomach Diseases
Diagnosis of Gastric Lesions From Exhaled Breath and Saliva
The investigators study the feasibility of a novel method in oncology based on breath analysis with a nanosensors array for identifying gastric diseases.
- Trial name
- NCT01420588
- Where
- 2 sites in China, Latvia
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Anhui Medical University
Colorectal Cancer, Colorectal Adenoma
Volatile Markers in Digestive Cancer
The study is aimed to determine the potential of volatile marker testing for identification of gastrointestinal cancers (in particular - colorectal and gastric cancers), the related precancerous lesions in the stomach and colon.
- Conditions
- Colorectal Cancer, Colorectal Adenoma, Gastric Cancer, Peptic Ulcer Disease
- Trial name
- VOLGACORE (NCT02332213)
- Testing
- Breath sampling for volatile marker detection, Upper endoscopy with biopsies, Colonoscopy with biopsies or lesion removal when required
- Where
- 2 sites in Latvia, Lithuania
- Volunteers
- 2,022 people, healthy volunteers welcome
- Sponsor
- University of Latvia