Clinical trials: Lesion
Dental Caries
Reminerlization Potential of GSE Gel versusCPP-ACP in Carious White Spot Lesions in Post Orthodontic Patients
Assess the effectiveness of applying grape seed extract (GSE) gel versus casein phosphopeptide-amorphous calcium phosphate (MI) paste on remineralization of white spot lesion (WSLs) in post orthodontic patients.
- Trial name
- NCT03966378
- Testing
- Grape seeds extract, Casein-phosphopeptide/amorphous-calcium phosphate
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Colorectal Adenoma, Colorectal Lesions
Cold Snare Versus Cold Forceps Polypectomy for Small Lesions
The goal of this clinical trial is to compare the efficacy and the safety of a new device for cold forceps polypectomy (CFP)- a special jumbo forceps- to cold snare polypectomy (CSP) for small colorectal lesions, without adding…
- Trial name
- Cold-SNAPS (NCT06970808)
- Testing
- Sampling from the resection margins
- Where
- Italy
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Azienda USL Modena
Nervous System Diseases (C10 Unique ID D009422)
Ultra-Low Field (ULF) Point-of-Care (POC) MRI System for Brain Morphology and Pathology
Background: Magnetic resonance imaging (MRI) is a tool for getting pictures of the tissues and organs inside the body. MRI can help diagnose many injuries and diseases. But not all patients are equally likely to receive MRIs.
- Trial name
- NCT06203626
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Peripheral Vascular Disease
Atrium iCAST Iliac Stent Pivotal Study
Prospective, multicenter, non-randomized, single-arm registry to evaluate the safety and effectiveness of the iCAST Covered Stent System in the treatment of patients with symptomatic claudication or rest pain and angiographic…
- Trial name
- iCARUS (NCT00593385)
- Testing
- iCAST covered stent
- Where
- 25 sites in United States, Germany
- Volunteers
- 165 people
- Sponsor
- Atrium Medical Corporation
Fibromuscular Dysplasia
Cohort Follow-up of Patients With Renal or Craniocervical Fibromuscular Dysplasia
PROFILE is a cohort study evaluating the progression of fibromuscular dysplasia lesions. This study is the prospective dimension of ARCADIA registry (ClinicalTrials.gov Identifier: NCT02884141), which aims to document phenotypic…
- Trial name
- PROFILE (NCT02961868)
- Testing
- Abdominal and supra-aortic trunks vascular imaging, Blood sampling (genetic), Blood sampling (biomarkers)
- Where
- 17 sites in Belgium, France
- Volunteers
- 340 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Trachea Diseases, Airway Remodeling
Feasibility of Tracheobronchial Defect Reconstruction Using Allogenic Aortic Patch
The investigators investigate the feasibility and safety of using cryopreserved aortic patches for tracheal or bronchial defect repair.
- Conditions
- Trachea Diseases, Airway Remodeling, Reconstruction Surgery
- Trial name
- NCT06935110
- Testing
- Cryopreserved aortic patch
- Where
- 2 sites in Taiwan
- Volunteers
- 10 people
- Sponsor
- National Taiwan University Hospital
Cervical Lesion
Clinical Evaluation of Bulk-fill Alkasite Restoration Versus Resin Modified Glass Ionomer in Adult With Class V Carious
Cention N will have the same clinical performance as resin-modified glass ionomer in cervical carious lesions. Evaluation of restorations will be done at baseline, six months, and one year according (USPHS) criteria.
- Trial name
- NCT04716517
- Testing
- Alkasite bioactive restorative material., Resin Modified Glass Ionomer
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Skin Cancer, Benign Skin Tumor, Inflammatory Skin Disease
Optical Tomographic Scanner for Skin Lesions
Optical coherence tomography is technology widely used in medicine. In this study, the investigators will use an optical tomographic scanner to scan skin tissue image.
- Trial name
- NCT02891291
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Rotator Cuff Tear
Polyester Patch in Massive Rotator Cuff Repair Improves Healing
The purpose of this study was to assess the impact and potential advantage of a novel synthetic patch augmentation in repair of massive rotator cuff (RC) tears, using clinical and radiological approaches.
- Trial name
- NCT02976285
- Testing
- arthroscopic rotator cuff repair with a polyester patch
- Volunteers
- 54 people
- Sponsor
- Etzel Clinic
Breast Lesions, Breast Cyst
Survey of Optical Values of the Breast Using Radiation-Free Pressure-Free Optical Scanning
The purposes of this study is to establish normal optical values of breast tissue in the general population. This will allow for establishing normals for breast composition, and is expected to be useful in the classification of…
- Conditions
- Breast Lesions, Breast Cyst, Early-Stage Breast Cancer, Benign Growth, Breast
- Trial name
- NCT00671385
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Spectros Corporation
Bone Diseases
Evaluation of Vitoss With and Without BMA for Benign Cavitary Lesions
This is a retrospective, two-arm study reviewing the healing of cavitary defects in patients treated with Vitoss alone versus those treated with Vitoss with bone marrow aspirate (BMA).
- Trial name
- NCT02165943
- Testing
- Vitoss
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Orthovita d/b/a Stryker
Aortic Aneurysm, Thoracic, Pseudoaneurysm
Evaluation of the GORE® Ascending Stent Graft
The primary objective of ARISE II is to assess the safety and effectiveness of the GORE® Ascending Stent Graft device in the treatment of lesions involving the ascending aorta and aortic arch.
- Conditions
- Aortic Aneurysm, Thoracic, Pseudoaneurysm, Aortic Dissection, Aorta; Lesion
- Trial name
- ARISEII (NCT05800743)
- Testing
- GORE® Ascending Stent Graft (ASG device), GORE® Thoracic Aortic Graft Thoracic Branch Endoprosthesis (TBE Device), Surgery
- Where
- 41 sites in United States
- Volunteers
- 370 people
- Sponsor
- W.L.Gore & Associates
Polypoid Lesions
Evaluation of Check-Cap C-Scan System in Providing Structural Information and Detection of Polypoid Lesions
The purpose of this study is to establish the efficacy of Check-Cap's C-Scan System in providing structural information on colonic polypoid lesions and masses, as an adjacent tool to FIT.
- Trial name
- NCT02990715
- Testing
- C-Scan System
- Where
- 3 sites in Israel
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Check-Cap Ltd.
Solid Pancreatic Mass Lesions
EUS-FNA With and Without Suction
To compare the number of passes required for cellblock acquisition with and without suction using the 25g needle.
- Trial name
- NCT02072915
- Testing
- Suction
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Alabama at Birmingham
Endometrial Neoplasms
Endometrial Lesions Predictions
To explore the risk factors of endometrial lesions in patients with abnormal uterine bleeding and establish prediction models which can discriminate between different endometrial etiologies of abnormal uterine bleeding(AUB).
- Trial name
- NCT05588076
- Testing
- no intervention
- Where
- China
- Volunteers
- 900 people
- Sponsor
- Beijing Friendship Hospital
Ischemic Lesions
Ischemic Preconditioning. Prospective Comparison
Vascular occlusion is used to reduce blood loss during liver resection (LR), but may cause ischemic damage to the remnant liver and can lead to liver failure in case of chronic liver disease.
- Trial name
- IP (NCT01432548)
- Testing
- ischemic preconditioning
- Where
- Argentina
- Volunteers
- 60 people
- Sponsor
- Hospital General de Agudos "Dr. Cosme Argerich"
Coronary Bifurcation Lesion
Efficacy and Safety of Sirolimus-Coated Spiral Balloon for Coronary Bifurcation Lesions
This is a multicenter, prospective randomized controlled study to evaluate the safety and effectiveness of Sirolimus-coated spiral balloon (SuperFlow®) versus Paclitaxel-coated balloon (Bingo™) in the treatment of coronary…
- Trial name
- NCT06618248
- Testing
- Sirolimus coated balloon angioplasty, Paclitaxel coated balloon angioplasty
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Dongguan TT Medical
Articular Cartilage Lesion of the Knee
INSTRUCT for Repair of Knee Cartilage Defects
The purpose of this study is to investigate whether the INSTRUCT therapy is safe and effective in the treatment of cartilage defects of the knee.
- Trial name
- NCT01041885
- Testing
- INSTRUCT
- Where
- 6 sites in Belgium, Poland and 1 more
- Volunteers
- 40 people
- Sponsor
- CellCoTec B.V.
Unilateral Primary Osteoarthritis of Knee, Osteoarthritis Knee
Microdrilling Surgery for Full Thickness Chondral Lesions of the Knee Augmented With Concentrated Bone Marrow Aspirate, Platelet Rich Plasma and Hyaluronic Acid
This study seeks to evaluate a treatment for multiple full thickness chondral lesions in the knee. Eligible subjects will undergo a microdrilling surgery and up to 12 post operative intra-articular injections of bone marrow…
- Conditions
- Unilateral Primary Osteoarthritis of Knee, Osteoarthritis Knee, Degeneration; Articular Cartilage, Knee, Degenerative Lesion of Articular Cartilage of Knee
- Trial name
- NCT02285725
- Testing
- Microdrilling Surgery, Injections of BMAC + PRP + HA
- Volunteers
- 21 people
- Sponsor
- Joseph E. Broyles
Carcinoma, Squamous Cell
Detecting Lesions in the Oral Cavity With Thermal Imaging
Previous studies indicate that there are significant differences in the temperature of tumors and normal, adjacent tissues. The present study will test this hypothesis for lesions in the oral cavity.
- Trial name
- NCT00868725
- Testing
- no intervention, observation only
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
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