Clinical trials: Lesion
Meningioma, Tumor, Brain
MiDura-Study (Neuro-Patch in Duraplasty)
The aim of this study is to collect systematically and proactively data regarding the performance of Neuro-Patch, like complications and handling, under daily clinical practice when used as intended by the manufacturer
- Conditions
- Meningioma, Tumor, Brain, Chiari Malformation, Vascular Malformation
- Trial name
- MiDura (NCT04189172)
- Where
- 4 sites in France, Germany
- Volunteers
- 328 people
- Sponsor
- Aesculap AG
Coronary Artery Disease
Bingo Drug-eluting Balloon Versus a Drug-eluting Stent for Coronary Bifurcation Lesions
Bingo drug-eluting balloon versus a drug-eluting stent for coronary bifurcation lesions: a prospective, multi-center, randomized, non-inferiority trial
- Trial name
- NCT06441539
- Testing
- Bingo® Paclitaxel coated balloon, Xience® Alpine Everolimus Eluting Coronary Stent System
- Volunteers
- 218 people
- Sponsor
- Yinyi(Liaoning) Biotech Co., Ltd.
Treatment Of Stenotic Lesions In Native Coronary Arteries.
BioFreedom FIM Clinical Trial.
Prospective, multi center, randomized, single blinded study designed to demonstrate the safety and effectiveness of the Biosensors BioFreedom Drug-Eluting Coronary Stent Delivery System at multiple time points compared to the…
- Trial name
- NCT01172119
- Testing
- Biofreedom Drug Eluting Stent, Tuxus Liberte Drug Eluting Stent
- Where
- 4 sites in Germany
- Volunteers
- 182 people
- Sponsor
- Biosensors Europe SA
Persistent Air Leaks
PATCHVALVE: Endobronchial Valves Plus Blood Patch for Persistent Air Leaks
The goal of this study is to evaluate the real-world safety and effectiveness of combining endobronchial valve (IBV) placement with endobronchial blood patching (EBP) for the treatment of persistent air leaks (PALs) in adult…
- Trial name
- NCT07184528
- Testing
- Endobronchial Blood Patch, Spiration Valve System (SVS) Placement
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Beth Israel Deaconess Medical Center
Gastric Mucosal Lesion
Efficacy and Safety of OsrhCT Before Upper Endoscopy on Improving Visualization of the Gastric Mucosa.
Study was designed to evaluate efficacy and safety of OsrhCT before upper endoscopy on visibility of gastric mucosa. A total of 40 subjects (both male and female) are expected to be enrolled in this trial.
- Trial name
- NCT07893600
- Testing
- Recombinant Human Chymotrypsin(OsrhCT) 4000U
- Volunteers
- 40 people
- Sponsor
- Healthgen Biotechnology Corp.
Brain Tumor, Brain Lesion
Intraoperative Functional Ultrasound
A wide spectrum of methods is used to image brain activation in vivo. It can be directly detected by neurons electrical activity imaging (cortical simulation mapping, calcium imaging, voltage sensitive dyes) or indirectly by…
- Trial name
- FUSIMAGINE (NCT02656407)
- Testing
- Ultrasound device
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Odontogenic Cysts, Keratocysts of the Jaw
Decompression of Odontogenic Cysts
The aim of this case-control study is to evaluate the effects of decompression of cystic jaw lesions by means of comparing pre- and post-decompression histologic findings.
- Conditions
- Odontogenic Cysts, Keratocysts of the Jaw, Cysts Dental, Pathology
- Trial name
- NCT06536907
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Diabetes Mellitus, Coronary Arterial Disease (CAD)
Randomised Trial of Dual Device Treatment Involving Drug-coated Balloon Angioplasty and Drug-eluting Stent Implantation Compared to Single Device Treatments in Patients With Diabetes Mellitus
Purpose of this study: The purpose of the study is to find out whether using a drug coated balloon in combination with a drug-eluting stent is better than the standard practice of using either device on its own.
- Conditions
- Diabetes Mellitus, Coronary Arterial Disease (CAD), de Novo Coronary Lesions, De Novo Stenosis
- Trial name
- DUBSTENT-DM (NCT07303439)
- Testing
- Percutaneous Coronary Intervention
- Where
- Ireland
- Volunteers
- 120 people
- Sponsor
- Royal College of Surgeons, Ireland
Acute Knee Cartilage Injury, Tear of Articular Cartilage of Knee, Current
EAGLE European Post Market Study
Prospective, multi-center, non-randomized, historical controlled, post-market study of patients requiring surgical repair of a focal articular cartilage lesion or osteochondral defect in the knee.
- Trial name
- EAGLE (NCT02309957)
- Testing
- BioMatrix CRD
- Where
- 6 sites in Germany, Italy and 2 more
- Volunteers
- 33 people
- Sponsor
- Kensey Nash Corporation
Cardiovascular Diseases, Arteriosclerosis
Registry of Coronary Lithotripsy in Spain.
The REPLICA TRIAL tries to assess the intracoronary lithotripsy safety and efficacy profiles in real-world patients with calcified coronary artery disease.
- Conditions
- Cardiovascular Diseases, Arteriosclerosis, Arterial Occlusive Diseases, Vascular Diseases
- Trial name
- REPLICA (NCT04298307)
- Testing
- Intracoronary lithotripsy (ICL)
- Where
- 26 sites in Spain
- Volunteers
- 426 people
- Sponsor
- Fundación EPIC
Coronary Artery Disease, Calcification
Intravascular Lithotripsy for Acute Stent Under-expansion in Calcified Coronary Lesions
Percutaneous coronary intervention (PCI) is the standard treatment for patients with coronary artery disease who have an indication for surgery.
- Trial name
- NCT06669195
- Testing
- Intravascular lithotripsy group, high-pressure balloon group
- Volunteers
- 40 people
- Sponsor
- Xuzhou Third People's Hospital
Coronary Ostium Stenosis, Myonecrosis
Side Branch Predilatation Strategy in Coronary Bifurcation Lesion Stenting (SBPS)
The role of Side Branch (SB) predilatation during coronary bifurcation lesion percutaneous coronary intervention (PCI) is still not established.
- Trial name
- SBPS (NCT01430377)
- Testing
- SB predilatation, No SB predilatation
- Where
- Bulgaria
- Volunteers
- 120 people
- Sponsor
- Medica Cor Heart Hospital
Acute Coronary Syndromes
Effect of rHDL on Atherosclerosis - Safety and Efficacy: THE ERASE TRIAL
Currently available therapies to treat Acute Coronary Syndromes(ACS) have several limitations including; the relatively long treatment duration required before apparent significant benefit; the inability to achieve reversal of…
- Trial name
- NCT00225719
- Testing
- rHDL
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- CSL Limited
Atypical Squamous Cells of Undetermined Significance, Cervical Cancer
SGN-00101 Vaccine in Treating Human Papillomavirus in Patients Who Have Abnormal Cervical Cells
This randomized phase II trial is studying how well SGN-00101 vaccine works compared to a placebo in treating human papillomavirus and preventing cervical cancer in patients with abnormal cervical cells.
- Conditions
- Atypical Squamous Cells of Undetermined Significance, Cervical Cancer, High-grade Squamous Intraepithelial Lesion, Low-grade Squamous Intraepithelial Lesion
- Trial name
- NCT00091130
- Testing
- HspE7, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- National Cancer Institute (NCI)
Coronary Artery Disease, Chronic Coronary Syndrome
Very Long Versus Overlapping Stents in Long Coronary Lesions
This study is performed to compare the angiographic and clinical outcomes of the use of single long stent versus overlapping stents in the treatment of long coronary lesions in patients with chronic coronary syndrome.
- Conditions
- Coronary Artery Disease, Chronic Coronary Syndrome, Drug Eluting Stents
- Trial name
- NCT04738344
- Testing
- Percutaneous Coronary Intervention and Stent Implantation
- Where
- 2 sites in Egypt
- Sponsor
- The Young Investigator Group of Cardiovascular Research
Tenosynovial Giant Cell Tumor
Accuracy of Indocyanine Green (ICG) Fluorescence Imaging in Tenosynovial Giant Cell Tumor Surgery
This study evaluates the diagnostic accuracy of Indocyanine Green (ICG) fluorescence imaging in visualizing Tenosynovial Giant Cell Tumor (TGCT) lesions during surgery.
- Trial name
- ICG-TGCT (NCT07315841)
- Testing
- Indocyanine Green
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
VITELLIFORM LESIONS
Radiomic Analysis in OCT Imaging of Acquired Vitelliform Lesions.
Vitelliform lesions (VLs) are subretinal accumulations of yellowish material on fundoscopy that correspond to hyperautofluorescent material on fundus autofluorescence (FAF) and hyperreflective subretinal material on structural…
- Trial name
- NCT07074041
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Federico II University
Pain
Bioequivalence and Adhesion Comparison of Buprenorphine Patches
To compare a 2nd generation Buprenorphine Transdermal System (BTDS) patch with a marketed 1st generation BTDS patch to confirm that the two are bioequivalent (deliver the same amount of drug) and that they equally both stick to…
- Trial name
- NCT02268422
- Testing
- Buprenorphine
- Where
- 2 sites in United Kingdom
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Mundipharma Research Limited
Periapical Lesions
Platelet Rich Plasma in Healing of Through and Through Periradicular Lesions
Title : Evaluation of the efficacy of Platelet Rich Plasma (PRP) in healing of through and through lesions Rationale: Bone replacement analogues have been used in the healing after periapical surgery.
- Trial name
- NCT03430557
- Testing
- PRP, periapical surgery without PRP
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Obesity, Periodontitis
Evaluation of the Dental Health Condition in Obesity Patients Before and After Bariatric Surgery
The aim of this study is to investigate whether there was an association between obesity and periodontitis, tendency to caries and periapical lesions.
- Conditions
- Obesity, Periodontitis, Caries, Periapical Lesion
- Trial name
- NCT00531154
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
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