Clinical trials: Leukoderma
Psoriasis, Cutaneous T Cell Lymphoma
Mechanisms of Action of Photo(Chemo)Therapy in Skin Diseases
The molecular mechanisms of action of photo(chemo)therapy in skin diseases are investigated in this study. The phototherapeutic modalities employed include UVB (ultraviolet B), UVA (ultraviolet A), PUVA (psoralen+UVA) and/or…
- Conditions
- Psoriasis, Cutaneous T Cell Lymphoma, Lymphoproliferative Disorders, Eczema
- Trial name
- BioUV2017 (NCT03340155)
- Testing
- Photo(chemo)therapy
- Where
- Austria
- Volunteers
- 240 people
- Sponsor
- Medical University of Graz
Cervical Pain
Effects of Kinesio Taping in Addition to Routine Physical Therapy on Pain, Range of Motion and Functional Disability in Patients With Upper Cross Syndrome
Objective of the study is to compare the effects of kinesio taping and routine physical therapy on pain, range of motion and functional disability in patients with upper cross syndrome.It is a single blinded randomized controlled…
- Trial name
- NCT05191043
- Testing
- Kinesio Taping Technique, Routine Physical Therapy
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- University of Lahore
Vitiligo
Comparison of Efficacy and Safety of 0.1% Tacrolimus and 0.1% Mometasone Furoate for Adult Vitiligo
Vitiligo has remained a difficult disease to treat. Previous available therapies are often ineffective. It usually takes several months or years for complete repigmentation and some areas of the body get at best only partial…
- Trial name
- NCT01333410
- Testing
- tacrolimus ointment, Mometasone furoate
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University
Vitiligo
Effect of Combination Non Steroidal Antiinflammatory Drugs and Narrowband UVB Treatment in Non-Photoadapters
Narrow band UVB phototherapy is the mainstay of therapy for vitiligo. However, about 1/3 of patients cannot respond to phototherapy.
- Trial name
- NCT05256147
- Testing
- Ibuprofen
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Vitiligo
A New Micrografting Technique for Vitiligo
This study evaluates micrografting using a harvesting and grafting process that has been designed by Momelan Technologies. The overall concept is to harvest several small pieces of skin, each measuring about 1.75 mm in diameter…
- Trial name
- NCT01262547
- Testing
- Dermabrasion-Micrografting, Dermabrasion
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Massachusetts General Hospital
Vitiligo
A 52-Week Study to Learn About the Safety and Effects of Ritlecitinib in Participants With Nonsegmental Vitiligo
This study is to evaluate how safe and effective ritlecitinib is in participants with non-segmental vitiligo (NSV). Ritlecitinib is studied in patients with non-segmental vitiligo.
- Trial name
- Tranquillo LTE (NCT06163326)
- Testing
- Ritlecitinib, Ritlecitinib 100 mg
- Where
- 73 sites in United States, Australia and 11 more
- Volunteers
- 394 people
- Sponsor
- Pfizer
Vitiligo, Hearing Loss
Audiological Disturbances in Vitiligo
The purpose of this study is to determine wether vitiligo patients have more audiological abmnormalities, than the healthy population.
- Trial name
- NCT00484224
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Vitiligo
Study of the Role of Innate Lymphoid Cells and Natural Killer Cells in Immune Activation of Vitiligo - INNATE Vitiligo
The cohort included only major patients with non-segmental vitiligo and no other autoimmune or inflammatory associated diseases (except thyroiditis). Control subjects should have no autoimmune or inflammatory diseases.
- Trial name
- INNATEvitiligo (NCT03859518)
- Testing
- blood and skin samples
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Hypopigmentation
Characterization of Bacterial and Mycosis Skin Flora in Seborrheic Macular Hypopigmentation - Microbiome
Hypopigmented skin changes are commonly encountered by dermatologists. A new dermatological entity was identified as scattered, hypopigmented oval-shaped macules and patches distributed mostly in seborrheic area of the face and…
- Trial name
- Microbiome_SHM (NCT06908889)
- Testing
- Skin's lesion patients, Skin's lesion vulunteers
- Where
- 3 sites in France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Gingival Pigmentation
Influence of Adjunctive Acids Use on Esthetic Outcomes of Gingival Melanin Depigmentation: A Periodontal-Operative Pilot Randomized Clinical Trial
This pilot randomized clinical trial aims to evaluate the effect of adjunctive acid application on the esthetic outcomes of gingival melanin depigmentation.
- Trial name
- GMDAcidRCT (NCT07708792)
- Testing
- Citric acid
- Volunteers
- 30 people
- Sponsor
- Dijlah University
Vitiligo
A Trial to Test the Safety and Efficacy of TEV-53408 in Participants With Vitiligo
The purpose of the trial is to evaluate the safety of TEV-53408 when given as an under the skin injection to adults with vitiligo. Vitiligo is a condition where patches of skin lose color (pigment) and turn white.
- Trial name
- NCT06625177
- Testing
- TEV-53408
- Where
- 13 sites in United States
- Volunteers
- 66 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D LLC
Upper Cross Syndrome
Comparative Effects of Egoscue and Feldenkrais Exercises on in Upper Cross Syndrome
Upper cross syndrome is a common postural dysfunction that is caused due to alternating tightness and weakness in the opposite muscle groups of the neck, shoulders and upper back which results in abnormal postural deviations.
- Trial name
- NCT07628413
- Testing
- Egoscue exercises, Feldenkrais exercises
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Vitiligo
Building an Assessment Model for Vitiligo Activity and Prognosis Using Peripheral Blood Cytokine Profiles
Vitiligo is a chronic autoimmune disorder characterized by depigmented patches on the skin, which can pose significant psychosocial challenges, particularly for individuals with darker skin tones.
- Trial name
- NCT07298551
- Testing
- Serum Cytokine Assay
- Where
- China
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Vitiligo
Repigmentation Using Apremilast and Phototherapy In Diffuse VITILIGO
Vitiligo is a depigmentation disorder affecting 0.5 to 2% of the general population. It is an acquired pigmentary disorder of the skin and mucous membranes that is characterized by circumscribed, depigmented macules and patches.
- Trial name
- Rapid Vitiligo (NCT03036995)
- Testing
- Apremilast
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Vitiligo
Repigmentation of Stable Vitiligo Lesions Using Spray-On Skin™ Cells
To evaluate repigmentation and quality of life after treatment of stable vitiligo lesions using the RECELL Device.
- Trial name
- TONE (NCT05971381)
- Testing
- RECELL® Autologous Cell Harvesting Device
- Where
- 17 sites in United States
- Volunteers
- 109 people
- Sponsor
- Avita Medical
Vitiligo
A Study to Assess the Changes in Pigmentation and Safety of Afamelanotide in Patients With Vitiligo on the Face
The CUV104 study will assess the efficacy and safety of afamelanotide in patients with vitiligo on the face and body as a monotherapy in repigmentation.
- Trial name
- NCT05210582
- Testing
- Afamelanotide
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Clinuvel, Inc.
Vitiligo
Thymic Stromal Lymphopoietin (TSLP) in Vitiligo
study \& verify the hypothesis of the involvement of TSLP in the pathogenesis of vitiligo in comparison to their levels in the healthy control persons.
- Trial name
- NCT03367273
- Testing
- skin biopsy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Vitiligo - Macular Depigmentation
Comparative Study of Microneedling With Topical Minoxidil 5% ± NB-UVB in Stable Vitiligo"
This study is a randomized controlled trial comparing microneedling with topical minoxidil 5% versus microneedling with minoxidil combined with NB-UVB phototherapy in stable vitiligo.
- Trial name
- NCT07548918
- Testing
- microneedling with minoxidil 5% and NBUVB, Microneedling with Minoxidil5%
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sohag University
Vitiligo
Transplantation of Basal Cell Layer Suspension Using Derma-rolling System in Vitiligo
Actually the methods for melanocyte delivery are invasive and often sophisticated. The dermarolling system with needles causing tiny microinjuries in the epidermis could offer a minimally invasive and painless method of…
- Trial name
- NCT02962180
- Testing
- Dermabrasion with dermaroller
- Where
- Morocco
- Volunteers
- 10 people
- Sponsor
- Mohammed V Souissi University
Disaster, Vulnerable Populations
Nurses Taking On Readiness Measures - Mercer County, New Jersey
Nurses Taking On Readiness Measures (N-TORM) is an innovative nurse-driven household emergency preparedness (HEP) intervention modeled after an existing community intervention provided by emergency management personnel.
- Trial name
- NTORM (NCT05455580)
- Testing
- Nurses Taking On Readiness Measures (N-TORM)
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Hunter College of City University of New York