Clinical trials: Leukoderma
Indolent Systemic Mastocytosis
Masitinib in Severe Indolent or Smoldering Systemic Mastocytosis Unresponsive to Optimal Symptomatic Treatment
The purpose of this study is to evaluate the efficacy and safety of oral masitinib versus placebo in the treatment of patients suffering from smouldering or indolent systemic mastocytosis with severe symptoms of mast cell…
- Trial name
- NCT04333108
- Testing
- Masitinib, Best Supportive Care
- Where
- 17 sites in France, Germany and 6 more
- Volunteers
- 140 people
- Sponsor
- AB Science
Vitiligo
Excimer Lamp Versus Excimer Laser in Vitiligo Treatment
308 nm excimer lamp and 308 nm excimer laser have both provide interesting results in treating vitiligo. They have the same wavelength but the type of emission of the photons is different.
- Trial name
- NCT00696358
- Testing
- 308nm excimer lamp, 308nm excimer laser
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire de Nice
Upper Crossed Syndrome, Upper Cross Syndrome
Dynamic Neuromuscular Stabilization Versus Corrective Exercises in Upper Cross Syndrome
The purpose of the study will be to investigate dynamic neuromuscular stabilization versus National American Academy of Sports Medicine (NASM) corrective exercises on pain, functional disability, cranio-vertebral angle, forward…
- Conditions
- Upper Crossed Syndrome, Upper Cross Syndrome, Upper Crossed Syndorme
- Trial name
- DNS/NASM (NCT07698392)
- Testing
- Dynamic neuromuscular stabilization, NASM corrective exercises
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Neck Syndrome
Effects of Dry Needling in Patients With Upper Cross Syndrome
The study will be done to evaluate the effectiveness of dry needling of muscles involved in Upper Cross Syndrome. Muscles involved in upper cross syndrome are tight upper trap, Levator Scapulae, Sternocledomastoid , Pectorals…
- Trial name
- NCT04674904
- Testing
- Dry Needling, Hot pack , TENS , Stretching
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Vitiligo
Vitiligo Skin Transplantation
In vitiligo, the melanocytes are lost from the skin in certain areas. One treatment for vitiligo takes the melanocytes from areas of normal skin and places them on areas of that same person's body which have lost their color.
- Trial name
- MKTP (NCT00830713)
- Testing
- Melanocyte-keratinocyte transplantation procedure (MKTP)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Henry Ford Health System
Vitiligo
A Study to Evaluate the Mechanism of Action of Ruxolitinib Cream in Subjects With Vitiligo (TRuE-V MOA)
The purpose of the study is to evaluate the Mechanism Of Action (MOA) of ruxolitinib cream in vitiligo by assessing the change in biomarkers.
- Trial name
- NCT04896385
- Testing
- Ruxolitinib cream, Vehicle Cream
- Where
- 13 sites in United States, Canada and 1 more
- Volunteers
- 60 people
- Sponsor
- Incyte Corporation
Upper Cross Syndrome
Effects of Post Isometric Relaxation With Scapular Stabilization Exercises
The levator scapulae is an important postural muscle that tends to shorten or become tight because of overactivity and bad posture, leading to neck and shoulder pain.
- Trial name
- NCT05973682
- Testing
- Post-isometric relaxation and Conventional treatment, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Upper Cross Syndrome
Effect of Release of Upper Track of Deep Front Facial Line Versus Myofascial Release With IASTM on Patients With Upper Cross Syndrome
this study will be conducted to compare the effect of release of upper track of deep front facial line versus myofascial release with IASTM on patients with Upper Cross Syndrome.
- Trial name
- UCS (NCT06907459)
- Testing
- upper Track of Deep Front Facial Line realese, Myofascial Release With IASTM, supervised corrective exercises
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Vitiligo
A Study to Evaluate the Safety and Efficacy of FB102 in Patients With Non-segmental Vitiligo
A Randomized, Double-Blind, Placebo Controlled, Multi-center Study to Evaluate the Safety and Efficacy of FB102 in Patients with Non-Segmental Vitiligo.
- Trial name
- NCT06905873
- Testing
- FB102
- Where
- 6 sites in Australia, New Zealand
- Volunteers
- 64 people
- Sponsor
- Forte Biosciences, Inc.
Vitiligo
ERASE VITILIGO Early Repigmentation Approach for Stopping the Evolution of VITILIGO Prospective Multicentric Interventional Study With Blinded Evaluation
Vitiligo affects 1 to 2% of worldwide population and has a demonstrated impact on the quality of life. Optimal treatment of vitiligo requires to target the auto-immune inflammatory response (to halt the depigmentation process)…
- Trial name
- ERASE (NCT04843059)
- Testing
- The resident memory T-cell infiltrate in perilesional vitiligo skin
- Where
- 2 sites in France
- Volunteers
- 51 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Vitiligo Vulgaris
Autologous Nanofat Injection for Treatment of Stable Vitiligo
This randomized, split-site, within-participant controlled clinical study evaluated the efficacy and safety of a single session of autologous nanofat injection as an adjunct to narrowband ultraviolet B (NB-UVB) phototherapy in 20…
- Trial name
- NCT07763262
- Testing
- Autologous Nanofat Injection, NB-UVB Phototherapy
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Benha University
Laser-induced Hypopigmentation
Gingival Depigmentation by Diode Laser
Physiologic gingival pigmentation(PGP) is the most common type of gingival pigmentation and cosmetic concern particularly in gummy smile patients. Laser therapy is an effective and noninvasive treatment option.
- Trial name
- NCT02143375
- Testing
- 810 Diode Laser
- Where
- Iran
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Vitiligo, Topical Fluorouracil
Topical 5-Fluorouracil Effervescent Powder in the Treatment of Vitiligo
A novel approach for 5-Fluorouracil delivery based on a solid effervescent formulation is proposed . 5-Fluorouracil is water soluble (~50mg/ml) and therefore has been used for the development of novel topical formulations…
- Conditions
- Vitiligo, Topical Fluorouracil, Effervescent Mixture
- Trial name
- NCT05536856
- Testing
- a new effervescent mixture 5-florouracil formula, 5-Fluorouracil plain powder
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Atopic Dermatitis, Psoriasis
Determinants of Chronic Inflammatory Skin Disease Trajectories
Although it is well known that the clinical expression and course of chronic inflammatory skin diseases are highly variable, there are insufficient epidemiological data on this, and the factors that determine the manifestation…
- Conditions
- Atopic Dermatitis, Psoriasis, Lichen Planus, Alopecia Areata
- Trial name
- NCT05928169
- Testing
- Topical and systemic drugs
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Albinism, Ocular
Genetic Determinant of Foveolar Hypoplasia in Parents of Albinos Children
Fovea plana could be the phenoyipic translation of a genetic anomaly in one of the genes identified in albinisme
- Trial name
- ALAFOR (NCT03959605)
- Testing
- blood sample for genetic test, Ophtalmological examination
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Pulmonary Fibrosis, Healthy Volunteers
Analysis of Specimens From Individuals With Pulmonary Fibrosis
The etiology of pulmonary fibrosis is unknown. Analyses of blood, genomic DNA, and specimens procured by bronchoscopy, lung biopsy, lung transplantation, clinically-indicated extra-pulmonary biopsies, or post-mortem examination…
- Conditions
- Pulmonary Fibrosis, Healthy Volunteers, Hermansky-Pudlak Syndrome (HPS)
- Trial name
- NCT00084305
- Where
- United States
- Volunteers
- 315 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Idiopathic Pulmonary Fibrosis
23andMe IPF Research Study
The long term goal of this study is to increase genetic understanding of IPF to enable the development of an effective drug for IPF that can improve the lives of those living with the condition.
- Trial name
- IPF (NCT05028894)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 690 people
- Sponsor
- 23andMe, Inc.
Vitiligo
The Value of Using Mini-oral Pulse Steroid Therapy Along With Non Cultured Epidermal Cell Suspension (NCES) in Stable Resistant Vitiligo
Assessing the additive value of mini-oral pulse steroid therapy in surgical treatment of acral and difficult to treat sites of vitiligo
- Trial name
- NCES (NCT06974669)
- Testing
- oral steroid-dexamethasone, non cultured epidermal suspension
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Vitiligo
Insulin Like Growth Factor-1 Against Oxidative Stress in Vitiligo
Insulin like growth factor has a protective role on melanocytes against the oxidative stress. The aim is to investigate this effect in vitiligo patients.
- Trial name
- NCT05812079
- Testing
- skin biopsy examined by ELISA technique
- Volunteers
- 33 people
- Sponsor
- Cairo University
Vitiligo, Tacrolimus
Effectivness of Topical Tacrolimus Monotherapy in Patients With Vitiligo
The study will evaluate the effectiveness of Tacrolimus 0.03% ointment monotherapy in patients with vitiligo. Patients will be treated for 6 months and followed for 3 months after treatment. All types of vitiligo will be included.
- Trial name
- NCT03358082
- Testing
- Tacrolimus 0.03% Ointment, Hydrocortisone Acetate 1% Ointment
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University