Clinical trials: Leukoderma, open to volunteers
Vitiligo, Non-Segmental Vitiligo (NSV)
Study of D-2570 in Subjects With Non-Segmental Vitiligo
This study tests D-2570, an investigational drug, in people with non-segmental vitiligo to check its safety and effect on skin discoloration.
- Trial name
- D2570-206 (NCT07625891)
- Testing
- D-2570 Dose 1, D-2570 Dose 2, D-2570 Dose 3
- Where
- China
- Volunteers
- 160 people
- Sponsor
- InventisBio Co., Ltd
Vitiligo - Macular Depigmentation, Tacrolimus
COMPARISON OF EFFICACY AND SAFETY OF NARROWBAND UVB WITH 0.1% TACROLIMUS VS NARROWBAND UVB WITH 0.005% CALCIPOTRIOL IN TREATMENT OF VITILIGO
Patient of stable and limited vitiligo less than 20% BSA will be recruited And evaluation of efficacy and safety of narrowband UVB with topical tacrolimus vs narrowband UVB and calcipotriol will be assessed
- Trial name
- NB-UVB (NCT06880042)
- Testing
- Tacrolimus, Calcipotriol
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr ayesha wahid
Vitiligo
A Clinical Trial of Multiple Doses of GR2301 Injection Combined With Phototherapy in Trial Participants With Vitiligo
This is a randomized, double-blind, placebo-controlled Phase Ib/II clinical trial of multiple subcutaneous injections of GR2301 in combination with phototherapy to evaluate the tolerability, safety, pharmacokinetics, and…
- Trial name
- GREVIT (NCT07647237)
- Testing
- GR2301 injection
- Volunteers
- 116 people
- Sponsor
- Genrix (Shanghai) Biopharmaceutical Co., Ltd.
Leukoderma, Hypopigmentation
Fractional CO2 Laser vs Dermabrasion With 5-Fluorouracil for Acquired Leukoderma
This randomized controlled prospective single-blinded comparative clinical study aims to compare the efficacy and safety of fractional carbon dioxide (CO2) laser therapy versus mechanical dermabrasion, both combined with topical…
- Trial name
- NCT07837908
- Testing
- Fractional CO2 Laser, Dermabrasion, 5-Fluorouracil
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Al-Azhar University
Local Neoplasm Recurrence, Distantly Metastatic Malignant Neoplasm
Partial Breast Versus no Irradiation for Women With Early Breast Cancer
All early breast cancer patients are offered adjuvant breast radiation therapy (RT) after breast conserving surgery for an early breast cancer.
- Conditions
- Local Neoplasm Recurrence, Distantly Metastatic Malignant Neoplasm, Death, Fibrosis Breast
- Trial name
- NCT03646955
- Testing
- No partial breast irradiation
- Where
- 17 sites in Chile, Denmark and 2 more
- Volunteers
- 926 people
- Sponsor
- Danish Breast Cancer Cooperative Group
Vitiligo
Vitiligo Severity, Quality of Life, Work Productivity and Activity Impairment
translate and validate the vitiligo specific quality of life (VITIQOL) questionnaire to Arabic language. evaluate the effect of vitiligo on patient quality of life using vitiligo specific quality of life questionnaire (VitiQoL).
- Trial name
- NCT06877000
- Testing
- VITIQOL questionnaire
- Volunteers
- 400 people
- Sponsor
- Assiut University
Upper Cross Syndrome
Comparative Effects of Egoscue and Feldenkrais Exercises on in Upper Cross Syndrome
Upper cross syndrome is a common postural dysfunction that is caused due to alternating tightness and weakness in the opposite muscle groups of the neck, shoulders and upper back which results in abnormal postural deviations.
- Trial name
- NCT07628413
- Testing
- Egoscue exercises, Feldenkrais exercises
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Upper Crossed Syndrome
Cervical Position Sense, Core Stability, and Postural Balance in University Students With Upper Crossed Syndrome
This study aims to investigate the relationship between cervical position sense, core stabilization, and postural balance in university students aged 18-30 years with Upper Crossed Syndrome (UCS).
- Trial name
- NCT07577492
- Testing
- postural and balance assessment battery
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Istinye University
Physiologic Gingival Melanin Pigmentation
Gingival Depigmentation Using a 940 nm Diode Laser Versus Ceramic Bur
This randomized split-mouth clinical trial will compare the effectiveness of a 940 nm GaAlAs diode laser and a ceramic soft tissue trimmer for the treatment of physiologic gingival melanin pigmentation.
- Trial name
- NCT07841119
- Testing
- 940 nm GaAlAs Diode Laser, Ceramic Soft Tissue Trimmer
- Where
- Vietnam
- Volunteers
- 17 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Vitiligo, Atopic Dermatitis
An Observational Study of Patients With Dermatologic Disease
TARGET-DERM+ is an observational research study to conduct a comprehensive review of outcomes for patients with dermatologic disease (DD) and providers who treat these patients.
- Conditions
- Vitiligo, Atopic Dermatitis, Alopecia Areata, Hidradenitis Suppurativa (HS)
- Trial name
- TARGET-DERM+ (NCT07748169)
- Where
- United States
- Volunteers
- 2,000,000 people
- Sponsor
- Target PharmaSolutions, Inc.
Vitiligo, Non-Segmental Vitiligo (NSV)
Evaluation of Crisaborole 2% Versus Tacrolimus 0.1% Each Combined With Excimer Light in the Treatment of Stable Non-segmental Facial Vitiligo: a Prospective Randomized Controlled Study.
The goal of this clinical trial is to learn if topical application of crisaborole 2% ointment can treat stable patches of facial vitiligo in pediatrics and adult patients of both genders.
- Conditions
- Vitiligo, Non-Segmental Vitiligo (NSV), Stable Vitiligo
- Trial name
- NCT07904910
- Testing
- Crisaborole 2% topical ointment, tacrolimus 0.1%, Excimer Light therapy
- Where
- Egypt
- Volunteers
- 35 people
- Sponsor
- Cairo University
Upper Cross Syndrome
Kendall Versus Janda's Approach Along With Diaphragmatic Breathing Exercises in Upper Crossed Syndrome
Upper Crossed Syndrome (UCS) is a postural imbalance in the upper body characterized by shortened and tight muscles in the front and upper back, while weak muscles in the back and neck are stretched and underactive.
- Trial name
- NCT07724574
- Testing
- Kendall exercises, Janda's Approach
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Psoriasis (PsO), Vitiligo Vulgaris
Evaluation of Stigma Toward Patients With Alopecia Areata, Atopic Dermatitis, Vitiligo, and Psoriasis
Primary objective: The primary objective is to evaluate in the general population the difference between emotional reactions associated with facial involvement by four major dermatologic diseases: psoriasis, atopic dermatitis…
- Conditions
- Psoriasis (PsO), Vitiligo Vulgaris, Atopic Dermatitis, Areata Alopecia
- Trial name
- STIGMADERM (NCT06801821)
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Inherited Ophthalmic Diseases, Hypopigmentation Disorder
National Ophthalmic Genotyping and Phenotyping Network (eyeGENE (Registered Trademark)), Stage 3 - Expansion of DNA and Data Repositories for Rare Inherited Ophthalmic Diseases
Background: The eyeGENE (Registered Trademark) program is a research resource for inherited eye conditions which includes genotypic and phenotypic data, imaging, and a corresponding biobank of DNA samples from people with a…
- Conditions
- Inherited Ophthalmic Diseases, Hypopigmentation Disorder, Corneal Dystrophy, Blue-cone Monochromacy
- Trial name
- NCT06491615
- Where
- 2 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- National Eye Institute (NEI)
Chediak-Higashi Syndrome
Study of Chediak-Higashi Syndrome
Chediak-Higashi syndrome (CHS) is a rare autosomal recessive disorder characterized in its classical form by oculocutaneous albinism, a bleeding diathesis, recurrent infection due to abnormal neutrophil and natural killer cell…
- Trial name
- NCT00005917
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Vitiligo
Topical Methotrexate with Fractional CO2 Laser in Treatment of Non Segmental Vitiligo
This prospective, within subject clinical trial aims to evaluate the efficacy of combining fractional CO2 laser with topical methotrexate versus topical methotrexate alone in treating non-segmental vitiligo.
- Trial name
- NCT06877455
- Testing
- Fractional CO2 laser assisted PDT
- Volunteers
- 50 people
- Sponsor
- Assiut University
Neck Pain
Effects of MET and Biofeedback Strengthening With and Without Kinesiotaping in Upper Crossed Syndrome
This randomised controlled trial will aim to evaluate the combined effects of Muscle Energy Technique (MET) and biofeedback strengthening, with and without Kinesiotaping (KT), on pain, posture, deep neck flexor strength, and…
- Trial name
- NCT07079319
- Testing
- MET + Biofeedback Strengthening + Kinesiotaping, MET + Biofeedback Strengthening
- Where
- Pakistan
- Volunteers
- 58 people
- Sponsor
- Riphah International University
Upper Cross Syndrome
Effectiveness of Rib Mobilization Combined With Postural Correction Exercises in Individuals With Upper Crossed Syndrome
This randomized controlled trial aims to evaluate the effectiveness of rib mobilization combined with postural correction exercises in reducing pain, improving cervical posture, and enhancing rib and thoracic mobility among…
- Trial name
- NCT07573553
- Testing
- Rib Mobilization and Postural Correction Exercises, Postural Correction Exercises Only
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Riphah International University
Vitiligo
Efficacy of Upadacitinib After NECS in Vitiligo
The goal of this clinical trial is to investigate the efficacy of upadacitinib after NECS in participants with vitiligo. The main question it aims to answer is: whether the short time use of upadacitinib after NECS will improve…
- Trial name
- NCT06454461
- Testing
- Upadacitinib 15 MG
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Jilin University
Vitiligo - Evaluation of Methotrexate Iontophoresis and Topical Methotrexate Gel as Localized Treatment Approache
Methotrexate Iontophoresis Versus Methotrexate 1% Gel on Depigmentation in Vitiligo Patients
Vitiligo is a common autoimmune depigmenting disorder characterized by selective destruction of melanocytes. Methotrexate (MTX) has shown potential in stabilizing disease activity and promoting repigmentation; however, systemic…
- Trial name
- NCT07208890
- Testing
- Methotrexate Iontophoresis/a low-intensity electric current
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pharos University in Alexandria