Clinical trials: Leukoderma
Gingival Pigmentation
Efficacy of Microneedling With Vitamin C in Performing Gingival Depigmentation
The present study will be carried to clinically evaluate the efficacy of microneedling with vitamin C in performing gingival depigmentation in comparison with conventional scalpel and diode laser.
- Trial name
- NCT07070024
- Testing
- Vitamin C, Microneedling, Diode laser
- Volunteers
- 30 people
- Sponsor
- Fayoum University
Vitiligo
Tyrosine Vs Tacrolimus With NB-UVB in Vitiligo
The goal of this clinical trial is to learn if adding topical tacrolimus or topical tyrosine to narrowband UVB phototherapy works to treat vitiligo in adults. It will also learn about the safety of both combinations.
- Trial name
- NCT07532330
- Testing
- Narrowband UVB Phototherapy, Topical Tacrolimus 0.1% ointment, Topical Tyrosine 2% cream
- Where
- Egypt
- Volunteers
- 67 people
- Sponsor
- Minia University
Idiopathic Pulmonary Fibrosis
23andMe IPF Research Study
The long term goal of this study is to increase genetic understanding of IPF to enable the development of an effective drug for IPF that can improve the lives of those living with the condition.
- Trial name
- IPF (NCT05028894)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 690 people
- Sponsor
- 23andMe, Inc.
Gingival Pigmentation, Depigmentation
Gingival Hyperpigmentation Treatment
It is a clinical study conducted to evaluate the effect of vitamin C and Glucathonine injection of pigmented gingival tissue versus surgical removal by scalpel
- Conditions
- Gingival Pigmentation, Depigmentation, Vitamin C, Glutathione
- Trial name
- NCT07595705
- Testing
- Vitamin c and glutathione, Surgical depigmentation
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Upper Cross Syndrome, Temporomandibular Disorder (TMD)
Upper Cross Syndrome and Temporomandibular Dysfunction in University Students
This cross-sectional observational study aims to investigate the relationship between Upper Cross Syndrome (UCS), a postural imbalance characterized by forward head posture and rounded shoulders, and Temporomandibular Disorder…
- Trial name
- UCS-TMD (NCT07456748)
- Testing
- No Intervention: Observational Cohort
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Vitiligo
Oral Ginkgo Biloba and Narrow Band UVB in the Treatment of Vitiligo
Vitiligo is a common chronic skin disease with 1-4% prevalence. It has a significant psychosocial impact on patients and society. Different treatment modalities with variable success rates are available.
- Trial name
- GB (NCT01006421)
- Testing
- GINGKO BILOBA
- Where
- Saudi Arabia
- Volunteers
- 160 people
- Sponsor
- King Saud University
Patients With Active Non-segmental Vitiligo., Evaluation of the Efficacy of UVB and Fluticason Proprionate 0.05%
Effect of Fluticasone Proprionate 0.05% on Narrow Band UV-B in Active Vitiligo
Rationale: Vitiligo vulgaris is a common acquired pigment disorder, which is characterised by the development of depigmented macules. It develops probably due to immunedestruction of melanocytes.
- Conditions
- Patients With Active Non-segmental Vitiligo., Evaluation of the Efficacy of UVB and Fluticason Proprionate 0.05%, Cream Compared to NB-UVB Alone in Patients With Non-segmental Vitiligo
- Trial name
- NCT01246921
- Testing
- Fluticasone proprionate 0.05% cream
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Vitiligo, Hearing Loss
Audiological Disturbances in Vitiligo
The purpose of this study is to determine wether vitiligo patients have more audiological abmnormalities, than the healthy population.
- Trial name
- NCT00484224
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Vitiligo
A Comparative Study on the Efficacy of Blue Light Emitting Diodes Therapy Versus Targeted Narrow Band UVB in Stable Non-segmental Vitiligo Patients.
A comparative study on the efficacy of blue light emitting diodes therapy versus targeted Narrow band UVB in stable non-segmental vitiligo patients.
- Trial name
- Nb-UVB (NCT07174024)
- Testing
- Narrow Band UVB Treatment, blue light emitting diode
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Vitiligo
Improved Phototherapy in Patients With Vitiligo
Vitiligo is a common acquired depigmentation skin and mucosal disease in dermatology, with or without white hair. Vitiligo with white hair is difficult to treat.
- Trial name
- NCT05836441
- Testing
- Exposure to white patches, Exposure to edge of white patches and normal skin around white patches
- Where
- China
- Volunteers
- 110 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Vitiligo
A Study of INCB018424 Phosphate Cream in Subjects With Vitiligo
The purpose of this study will be to examine the efficacy, safety, and tolerability of ruxolitinib cream in subjects with vitiligo.
- Trial name
- NCT03099304
- Testing
- Ruxolitinib cream, Vehicle cream
- Where
- 26 sites in United States
- Volunteers
- 157 people
- Sponsor
- Incyte Corporation
Melanin Hyperpigmentation
Vitamin C Depigmenattion Versus Conventional Technique
Although physiologic gingival hyperpigmentation is not a pathologic condition, it is considered one of the main esthetic problems in dentistry.
- Trial name
- NCT03719274
- Testing
- vitamin c depigementation
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hyperpigmentation; Melanin, Laser-Induced Hyperpigmentation
Laser-Assisted Gingival Depigmentation
This randomized clinical trial evaluated the recurrence rates of physiological gingival pigments during 24 months follow-up and the patient perceptions after the ablative depigmentation using two laser wavelengths; Diode 940 nm…
- Trial name
- NCT04680806
- Testing
- Er,Cr:YSGG laser 2780 nm, Diode laser 940 nm
- Where
- Qatar
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Academy of Laser Dentistry - Gulf Laser Chapter
Gingival Hyperpigmentation
Gingival Depigmentation With Diode and Er,Cr:YSGG Laser: A Split-mouth Trial
Gingival hyperpigmentation is a common physiological condition caused by excessive melanin deposition in oral mucosa, negatively affecting smile esthetics.
- Trial name
- Laser (NCT07520266)
- Testing
- Er,Cr:YSGG laser, Diode laser
- Where
- 2 sites in Vietnam
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Can Tho University of Medicine and Pharmacy
Vitiligo, Treatment
Efficacy of Intralesional Triamcinolone Injection in the Treatment of Vitiligo
A randomized split-body pilot study was planned to confirm efficacy of intralesiona triamcinolone injection in patients with vitiligo
- Conditions
- Vitiligo, Treatment, Intralesional Injection, Corticosteroid
- Trial name
- NCT03365141
- Testing
- Triamcinolone acetonide 0.4mg/cc, Phototherapy (NBUVB or excimer laser), Topical tacrolimus
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- The Catholic University of Korea
Gingival Hyperpigmentation, Gingival Melanin Pigmentation
Vitamin C for Gingival Depigmentation
The purpose of this study is to evaluate the clinical and histopathological efficacy of topical vitamin C applications using three modalities (topical gel, microneedling , and mesotherapy) in gingival depigmentation.
- Trial name
- VitC-DePg (NCT07513727)
- Testing
- Topical Vitamin C ( control Arm), Vitamin C mesotherapy, Microneedling technique
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Al-Azhar University
Quality of Life, Ichthyosis
Qualitative Study in Patients With Genodermatoses and Healthcare Professionals on Reproductive Counselling
The goal of this observational study is to understand the perspectives and needs of patients with genodermatoses and their partners who wish to have children, regarding their decision-making process and their consideration of…
- Conditions
- Quality of Life, Ichthyosis, Palmoplantar Keratoses, Epidermolysis Bullosa
- Trial name
- NCT06330350
- Testing
- Qualitative interview
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- Maastricht University Medical Center
Vitiligo
Effect of Microneedling, Bimatoprost and Excimer in Vitiligo Treatment
The purpose of this research is to treat vitiligo with a topical PGF2α, microneedling and excimer laser. The goal is to have greater repigmentation than the standard of care (excimer) after 12 weeks of treatment.
- Trial name
- NCT04738149
- Testing
- Bimatoprost, Excimer laser, Microneedling with a dermaroller
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Upper Cross Syndrome
Comparative Effects of Janda and IASTM on UCS
Upper Crossed Syndrome (UCS) is a widespread muscle imbalance defined by tightness in the upper trapezius, pectoralis major and minor, and sternocleidomastoid, coupled with weakness in deep neck flexors, lower trapezius, and…
- Trial name
- IASTM UCS (NCT07372391)
- Testing
- Janda's Approach, Instrument Assisted Soft Tissue Mobilization (IASTM)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Vitiligo
Efficacy of Autologous Outer-Root-Sheath Melanocytes Transplantation in the Treatment of Vitiligo
The purpose of this study is to evaluate the hypothesis that, in patients with stable vitiligo unresponsive to conventional treatments including traditional phototherapy and/or topical steroids, the application of a non-cultured…
- Trial name
- NCT01923142
- Testing
- Outer-Root-Sheath Melanocytes Suspension
- Where
- 2 sites in Italy
- Volunteers
- 4 people
- Sponsor
- Centro Studi Gised