Clinical trials: Lichen
Lichen Sclerosus, Lichen Planus
Diagnostic Accuracy of "Three Rings Vulvoscopy" for Detection of Vulvar Dermatosis
The objective of the study was to determine sensitivity, specificity and diagnostic accuracy of "Three Rings Vulvoscopy" for detection of vulvar dermatosis using histopathology as the reference standard.
- Conditions
- Lichen Sclerosus, Lichen Planus, Lichen Simplex Chronicus, Vulvodynia
- Trial name
- DATRIV (NCT02732145)
- Testing
- "Three Rings Vulvoscopy" (TRIV), Histopathology
- Where
- Croatia
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Ginekološka Poliklinika Dr. Vesna Harni
Vulvar Lichen Sclerosus
Does Steroid Plus CO2 Laser Improve Lichen Sclerosus Symptoms Compared to Steroids Alone?
This study will compare the effects of fractionated CO2 laser plus topical steroids versus topical steroids alone in treatment of lichen sclerosus.
- Trial name
- NCT05243563
- Testing
- MonaLisa Touch, Topical steroid
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- University of South Alabama
Vulvar Lichen Sclerosus
Laser Treatment for Vulvar Lichen Sclerosus
The object of this non-randomized, prospective study is to assess the effectiveness of ablative fractional 2940 nm laser treatment of vulvar lichen sclerosus.
- Trial name
- NCT04134494
- Testing
- Ablative Fractional 2940 nm Laser
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Beth Israel Deaconess Medical Center
Lichen Sclerosus
A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Lichen Sclerosus
The purpose of this study is to evaluate the efficacy and safety of Ruxolitinib cream in participants With Lichen Sclerosus. This is randomized, double-blind, vehicle-controlled (DBVC) study with a DBVC period of 12 weeks…
- Trial name
- NCT05593445
- Testing
- Ruxolitinib cream, Vehicle cream
- Where
- 14 sites in United States, Canada
- Volunteers
- 61 people
- Sponsor
- Incyte Corporation
Vulvar Lichen Sclerosus
Efficacy and Safety of MC2-25 Cream & Vehicle in Women With Vulvar Lichen Sclerosus (VLS)
The purpose of this study is to explore the efficacy and safety of MC2-25 cream and MC2-25 vehicle in women with vulvar lichen schelosus (VLS).
- Trial name
- Orchid 1 (NCT06132919)
- Testing
- MC2-25 cream, MC2-25 vehicle
- Where
- Denmark
- Volunteers
- 33 people
- Sponsor
- MC2 Therapeutics
Frontal Fibrosing Alopecia, Lichen Planopilaris of Scalp
Effectiveness and Safety of Tofacitinib in Patients With Recalcitrant Frontal Fibrosing Alopecia : A Pilot Study
This study aims to determine the efficacy and safety of tofacitinib therapy in Thai patients with recalcitrant frontal fibrosing alopecia. The main questions are 1.
- Trial name
- Tofacitinib (NCT06202560)
- Testing
- Tofacitinib 5 MG
- Where
- Thailand
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Institute of Dermatology, Thailand
Lichen Planopilaris
A Study of Deucravacitinib to Treat LPP and FFA
The purpose of this clinical research study is to learn more about the use of Deucravacitinib in the treatment of Lichen Planopilaris.
- Trial name
- NCT06091956
- Testing
- Deucravacitinib
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Mayo Clinic
Lichen Planopilaris
Valchlor in the Treatment of Lichen Planopilaris
The primary objective of this study is to assess the potential effectiveness of once daily application of Valchlor in decreasing disease activity in patients with Lichen Planopilaris.
- Trial name
- NCT03417141
- Testing
- Mechlorethamine 0.016% Top Gel
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Mayo Clinic
Chronic Idiopathic Urticaria, Chronic Idiopathic Pruritus
A Study to Assess the Efficacy, Safety, and Tolerability of KPL-716 in Reducing Pruritus in Chronic Pruritic Diseases
Participants with diseases characterized by chronic pruritus experiencing moderate to severe pruritus will be enrolled in this pilot Phase 2 study.
- Conditions
- Chronic Idiopathic Urticaria, Chronic Idiopathic Pruritus, Lichen Planus, Lichen Simplex Chronicus
- Trial name
- NCT03858634
- Testing
- KPL-716
- Where
- 14 sites in United States
- Volunteers
- 58 people
- Sponsor
- Genentech, Inc.
Oral Lichen Planus
Evaluation of Green Tea as Antioxidant Agent in Management of Oral Lichen Planus
The study included forty individuals divided into 3 groups. 10 control subjects, 15 oral lichen planus (OLP) patients who were treated with topical corticosteroids and 15 oral lichen planus (OLP) patients who were treated with…
- Trial name
- NCT02329600
- Testing
- green tea tablets (Green tea extract 5:1) 200 mg, Triamcinolone Acetonide
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University