Clinical trials: Lichen Sclerosus
Vulvar Lichen Sclerosus
The CO2RE® System for Vulvar Lichen Sclerosus
Subjects with vulvar lichen sclerosus (VLS) will undergo fractional carbon dioxide (CO2) laser treatment to the vulvar area. Subjects will be evaluated for changes in clinical signs and architectural changes associated with VLS…
- Trial name
- NCT04148651
- Testing
- The CO2RE® System
- Where
- 4 sites in United States
- Volunteers
- 14 people
- Sponsor
- Candela Corporation
Vulvar Lichen Sclerosus
Clobetasol Propionate Versus Fractionated Carbon Dioxide Laser for the Treatment of Lichen Sclerosus
This study is being done to compare the effects, good and bad, of fractionated CO2 laser treatment and clobetasol propionate .05% ointment on vulvar lichen sclerosus.
- Trial name
- CuRLS (NCT02573883)
- Testing
- Fractionated Carbon Dioxide Laser, Clobetasol Propionate 0.05% ointment
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Medstar Health Research Institute
Lichen Sclerosus, Lichen Planus
Diagnostic Accuracy of "Three Rings Vulvoscopy" for Detection of Vulvar Dermatosis
The objective of the study was to determine sensitivity, specificity and diagnostic accuracy of "Three Rings Vulvoscopy" for detection of vulvar dermatosis using histopathology as the reference standard.
- Conditions
- Lichen Sclerosus, Lichen Planus, Lichen Simplex Chronicus, Vulvodynia
- Trial name
- DATRIV (NCT02732145)
- Testing
- "Three Rings Vulvoscopy" (TRIV), Histopathology
- Where
- Croatia
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Ginekološka Poliklinika Dr. Vesna Harni
Vulvar Lichen Sclerosus
Does Steroid Plus CO2 Laser Improve Lichen Sclerosus Symptoms Compared to Steroids Alone?
This study will compare the effects of fractionated CO2 laser plus topical steroids versus topical steroids alone in treatment of lichen sclerosus.
- Trial name
- NCT05243563
- Testing
- MonaLisa Touch, Topical steroid
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- University of South Alabama
Vulvar Lichen Sclerosus
Laser Treatment for Vulvar Lichen Sclerosus
The object of this non-randomized, prospective study is to assess the effectiveness of ablative fractional 2940 nm laser treatment of vulvar lichen sclerosus.
- Trial name
- NCT04134494
- Testing
- Ablative Fractional 2940 nm Laser
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Beth Israel Deaconess Medical Center
Lichen Sclerosus
A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Lichen Sclerosus
The purpose of this study is to evaluate the efficacy and safety of Ruxolitinib cream in participants With Lichen Sclerosus. This is randomized, double-blind, vehicle-controlled (DBVC) study with a DBVC period of 12 weeks…
- Trial name
- NCT05593445
- Testing
- Ruxolitinib cream, Vehicle cream
- Where
- 14 sites in United States, Canada
- Volunteers
- 61 people
- Sponsor
- Incyte Corporation
Vulvar Lichen Sclerosus
Efficacy and Safety of MC2-25 Cream & Vehicle in Women With Vulvar Lichen Sclerosus (VLS)
The purpose of this study is to explore the efficacy and safety of MC2-25 cream and MC2-25 vehicle in women with vulvar lichen schelosus (VLS).
- Trial name
- Orchid 1 (NCT06132919)
- Testing
- MC2-25 cream, MC2-25 vehicle
- Where
- Denmark
- Volunteers
- 33 people
- Sponsor
- MC2 Therapeutics