Clinical trials: Lidocaine
Contraception
Ethyl Chloride Spray Versus Subcutaneous Lidocaine Anaesthetic Prior to Contraceptive Implant Insertion
Study to look at the acceptability of local anaesthetic spray versus injection, prior to contraceptive implant insertion
- Trial name
- NCT02651207
- Testing
- Questionnaire based study looking at pain scores felt by patients either having a lidocaine injection or ethyl chloride spray prior to insertion of a contraceptive implant
- Volunteers
- healthy volunteers welcome
- Sponsor
- Tayside Medical Science Centre
Voice Disorders
Brain Mapping of Voice Control
Some voice disorders are caused by uncontrolled muscle actions that affect the larynx or voice box. The purpose of this study is to understand 1) how the brain controls voice production; 2) how changes in sensation within the…
- Trial name
- NCT00066911
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Covid19
Xylocaine to Freeze During Unpleasant Nasopharyngeal Swabs
Since the beginning of the COVID-19 pandemic, nasopharyngeal swabs (NPS) have been recommended to detect the virus. This procedure has been reported to be painful by 85% of children The aim of the study was to assess whether…
- Trial name
- Xylofuns (NCT04901065)
- Testing
- Xylocaine
- Where
- Canada
- Volunteers
- 88 people
- Sponsor
- Evelyne D.Trottier
Anesthesia of Mucous Membrane
Comparison of Topical and Nebulized Anesthesia in Patients Undergoing Esophago-Gastro-Duodenoscopy
This study compares the effect of nebulized lidocaine and lidocaine spray in patients undergoing esophago-gastro-duodenoscopy. The investigators evaluate the success rate of the procedure between two methods.
- Trial name
- NCT02317770
- Testing
- Lidocaine Spray, Nebulized Lidocaine
- Where
- Thailand
- Volunteers
- 110 people
- Sponsor
- Mahidol University
Pain, Acute, Laceration
Prospective Evaluation of Topical Analgesia for Laceration Repair in the Emergency Department
The purpose of this study is to determine if topical analgesia using a lidocaine and prilocaine cream improves pain scores compared to the usual local anesthesia using subcutaneous 1% lidocaine and adrenalin injected near the…
- Trial name
- NCT03071601
- Testing
- Lidocaine-Prilocaine Cream 2.5-2.5%, Lidocaine 1% Epinephrine 0.005mg/mL solution
- Where
- 2 sites in France
- Volunteers
- 132 people
- Sponsor
- Centre Hospitalier le Mans
Sleep Disturbance
Perioperative Lignocaine and Sleep Disturbance
The aim of this clinical trial is to study the effect of an intravenous infusion of lidocaïne in a multimodal analgesic protocol on the architecture sleep during the first postoperative night.
- Trial name
- NCT03317912
- Testing
- Lidocaïne 2%
- Volunteers
- 40 people
- Sponsor
- University of Liege
Symptomatic Irreversible Pulpitis
Assessment of Local Anaesthesia Effectiveness in Symptomatic Irreversible Pulpitis
This study aims to evaluate the comparative efficacy of two different local anaesthetic agents for supplemental buccal infiltration after a failed inferior alveolar nerve block in achieving profound pulpal anaesthesia for…
- Trial name
- LA AGENTS (NCT06862570)
- Testing
- 2% lignocaine with epinephrine 1.8 ml(36mg/ml lignocaine HCL, epinephrine bitartrate 0.0324mg/ml), 4% Articaine with epinephrine 1.7 ml (40mg/ml Articaine HCL, epinephrine bitartrate 0.018 mg/ml)
- Where
- Pakistan
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- 28 Military Dental Centre Lahore
Anesthesia, Local
Buffered vs Plain Lidocaine for Local Nasal Anesthesia
Transnasal Fiberoptic Laryngoscopy (TFL) is a common procedure in the otolaryngology clinic for the examination of vocal cord appearance and function, inspection and follow up of benign and malignant lesions, and investigating…
- Trial name
- NCT04583137
- Testing
- Lidocain
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Kfir Siag
Anesthesia
Anesthetic Efficacy in Irreversible Pulpitis
The purpose of this study was to compare the anesthetic efficacy of articaine, lidocaine and mepivacaine in patients with irreversible pulpitis of mandibular molar.
- Trial name
- NCT02054767
- Testing
- Intervention: inferior alveolar nerve block injection
- Where
- Brazil
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Pain During and After Endovenous Laser Obliteration of Large Saphenous Vein Based on Lidocaine Tumescent Concentration
Efficacy of Variable Lidocaine Concentrations in Tumescent Anesthesia for Pain Control During and After Endovenous Laser Procedure; Non-inferiority Trial
Endovenous laser treatment is a minimally invasive procedure that has been shown to be a safe and effective treatment for varicose veins.
- Trial name
- NCT02192411
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Midwest Vein Center
Postoperative Pain
A Pharmacokinetic (PK) Study of Extended-Release Epidural Morphine in Upper Abdominal Surgery
The primary purpose of this study is to evaluate the effects of lidocaine/epinephrine test dose administration on the PK profile of a single epidural dose of DepoDur (extended-release epidural morphine) in patients undergoing…
- Trial name
- NCT00728832
- Testing
- DepoDur (extended-release epidural morphine)
- Volunteers
- 39 people
- Sponsor
- EKR Therapeutics, Inc
Lip Augmentation
Postmarket Study of JUVÉDERM VOLBELLA™ With Lidocaine in the Lips
A prospective, multicenter postmarket study of the use of JUVÉDERM VOLBELLA™ with Lidocaine in the lips.
- Trial name
- NCT01629134
- Testing
- Crosslinked hyaluronic acid gel
- Where
- Germany
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Allergan Medical
Cough Suppression, Thyroidectomy
Effects of Dexmedetomidine Combined With Lidocaine Topical Administration on Cough Reflex During Extubation in Thyroidectomy Patient.
Study Hypothesis: The combination of dexmedetomidine and lidocaine administered as laryngopharyngeal topical spray provides superior suppression of extubation cough reflex compared to lidocaine alone or placebo, without…
- Trial name
- NCT07832214
- Testing
- · Dex-Lido solution: Dexmedetomidine 100 μg/mL (concentration) was diluted with 2% lidocaine to achieve final concentration of dexmedetomidine 1 μg/kg in 5 mL total volume, · Lido solution: 2% lidocaine, 5 mL, · Control solution: 0.9% normal saline, 5 mL
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Sohag University
Mid Face Volume Deficit
Clinical Investigation for Evaluating the Safety and Efficacy of JTM102 to Mid Face Volume Deficiency
This study is clinical investigation for evaluating safety and efficacy of JTM102 on temporary correction of mid-face volume deficiency
- Trial name
- NCT07265778
- Testing
- JTM102, Juvederm VOLUMA with Lidocaine
- Where
- South Korea
- Volunteers
- 149 people
- Sponsor
- Jetema Co., Ltd.
Thyroid Disease, Thyroid Surgery
Continuous Lidocaine Infusion in Thyroid Surgery Using Intraoperative Neurophysiological Monitoring
Thyroid surgery is a common procedure for the treatment of thyroid tumors, nodules and other related lesions. During this procedure, intraoperative neurophysiological monitoring is used to protect the recurrent laryngeal nerves.
- Conditions
- Thyroid Disease, Thyroid Surgery, Lidocaine Infusion
- Trial name
- NCT06785987
- Testing
- Continuous Lidocaine Infusion, intermittent fentanyl infusion, Continuous remifentanil Infusion
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Abdominal Pain, Renal Colic
High Dose IV Lidocaine vs Hydromorphone for Abdominal Pain in the Emergency Department
Intravenous lidocaine will be given at a dose of 2 mg/kg intravenously to patients in the emergency department with a diagnosis of acute abdominal pain.
- Trial name
- HIDO-LIDO (NCT04398316)
- Testing
- Lidocaine Iv, HYDROmorphone Injection
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Hennepin Healthcare Research Institute
Contraception
Comparative Safety and Efficacy of Vaginal Dinoprostone Versus Lidocaine-prilocaine Cream in Copper IUD Insertion
the aim of the present study is to Compare Safety and Efficacy of Vaginal dinoprostone Versus Lidocaine-prilocaine Cream in copper IUD Insertion in nulliparous women: a randomized controlled trial
- Trial name
- NCT04340778
- Testing
- vaginal dinoprostone, Lidocaine-prilocaine Cream
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Cairo University
Any Condition Requiring Vulvar Biopsy
Pain Perception During Vulvar Biopsy
The purpose of this study is to compare pain control during vulvar biopsy following either (1) application of EMLA (a eutectic mixture of local anesthetics lidocaine 2.5% and prilocaine 2.5%) cream or (2) injection of 1%…
- Trial name
- NCT03654417
- Testing
- EMLA, Lidocaine
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Duke University
Acute Pain
Intravenous Lidocaine in Total Knee Replacement
Osteoarthritis of knees and hips is a common medical problem present in elderly, which poses significant impairment to their mobility, independence, and quality of life.
- Trial name
- NCT03597776
- Testing
- Lidocaine, Saline
- Where
- Hong Kong
- Volunteers
- 62 people
- Sponsor
- The University of Hong Kong
Pain
The Neurobiology of Expectancy and Pain Perception
This study will use using fMRI (functional Magnetic Resonance Imaging) to elucidate how contextual learning/expectation relieves or aggravates pain experience in the same cohort of subjects and the same study session.
- Trial name
- NCT01575106
- Testing
- Heat pain applied using TSA or CHEPS
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
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