Clinical trials: Lidocaine Infusion
Inguinal Hernia
The Effect of Systemic Lidocaine Infusion to Postoperative Pain and Quality of Recovery After Laparoscopic Hernia Repair in Children
Systemic lidocaine administration may improve postoperative pain and recovery after laparoscopic inguinal hernia repair in pediatric patients
- Trial name
- NCT02007330
- Testing
- Systemic intravenous lidocaine infusion, Normal saline infusion
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Yonsei University
Opioid Free Anesthesia, Opioid Based Anesthesia
Intraoperative Infusion of Dexmedetomidine Versus Lidocaine or Magnesium Sulphate for Enhanced Quality of Recovery After Spine Surgery Fixation
Thoracolumbar fixation is a major spine surgery; it is performed to stabilize the spine after trauma, deformity or advanced degenerative disease.
- Conditions
- Opioid Free Anesthesia, Opioid Based Anesthesia, Spine Fixation Surgeries, Opiod-Related Disorders
- Trial name
- NCT07843953
- Testing
- Group ( L): LICOCAINE, GROUP Dexmedetomidine, Group M: Magnesium sulphate
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Rib Fractures, Rib Trauma
PVB vs Ketamine/Lidocaine in Rib Fracture Patients
Rib fractures are a common admission to the trauma service. The mainstay of treatment is pain control to improve respiratory effort in order to offset the risk of pneumonia and mechanical ventilation.
- Conditions
- Rib Fractures, Rib Trauma, Rib Fracture Multiple, Pain, Acute
- Trial name
- NCT04413799
- Testing
- lidocaine, ketamine intravenous infusion, paravertebral block with ropivicaine
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- George Washington University
Bariatric Surgery, Lidocaine
Intravenous Lidocaine Infusion Versus Intravenous Dexmedetomidine Infusion During Sleeve Gastrectomy
Although laparoscopic (LAP) bariatric surgery is minimally invasive. Following any laparoscopic procedure, patients typically experience the peak of postoperative pain within the first 24 hours.
- Conditions
- Bariatric Surgery, Lidocaine, Dexmedetomidine
- Trial name
- NCT07327905
- Testing
- intravenous lidocaine, intravenous dexmedetomidine
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Hemodynamic Responses, Laparoscopic Cholecystectomy
Hemodynamic Responses of Dexmedetomidine, Lidocaine or Propofol Infusions During Laparoscopic Cholecystectomy
This study will be carried out to compare the efficacy of dexmedetomidine, propofol or lidocaine infusions in attenuation of hemodynamic responses to pneumoperitoneum during adult laparoscopic cholecystectomy using electrical…
- Conditions
- Hemodynamic Responses, Laparoscopic Cholecystectomy, Dexmedetomidine, Lidocaine
- Trial name
- NCT05937282
- Testing
- Dexmedetomidine, Propofol, Lidocain
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Menoufia University
Duodenal Spasm, ERCP
Effect of IV Lidocaine on Duodenal Peristalsis and Sedation in ERCP
This study aims to evaluate the efficacy of intravenous lidocaine infusion on duodenal peristalsis during Endoscopic Retrograde Cholangiopancreatography (ERCP).
- Conditions
- Duodenal Spasm, ERCP, Sedation
- Trial name
- LIDO ERCP (NCT07333859)
- Testing
- Lidocaine Hydrochloride 2%, 0.9 % Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara City Hospital Bilkent
Colorectal Cancer
Effect of Lidocaine on Postoperative Pain and Long-term Survival in Elderly Patients Undergoing Colorectal Surgery
This study is a further observation and follow-up of the patients enrolled in the registration number NCT05920980 to further evaluate the effect of long-term infusion of lidocaine on postoperative chronic pain, long-term quality…
- Trial name
- NCT06405776
- Testing
- lidocaine
- Where
- China
- Volunteers
- 276 people
- Sponsor
- West China Hospital
Analgesia
Opioid Sparing Analgesia Continuous Intraoperative Infusion of Dexmedetomidine Versus Lidocaine for Laparoscopic Cholecystectomy
Opioid sparing analgesia: Continuous intraoperative infusion of dexmedetomidine versus lidocaine for laparoscopic cholecystectomy, a randomized double-blind clinical trial.
- Trial name
- NCT05788393
- Testing
- Dexmedetomidine Injection [Precedex], Lidocaine IV
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Assiut University
Postoperative Analgesia
Postoperative Analgesia in Patients Undergoing Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy (PCNL) is a minimally invasive procedure to remove stones from the kidney by a small puncture wound through the skin.
- Trial name
- NCT06078241
- Testing
- Intravenous lidocaine infusion, Erector spinae plane block (ESPB), Intravenous infusion of normal saline
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Ain Shams University
Fracture Arm, Fracture Closed of Lower End of Forearm, Unspecified
A Clinical Trial on the Use of Lidocaine Infusion During Surgery for Pediatric Upper Extremity Fractures and Its Impact on Total Perioperative Opioid Requirements
This study is a prospective, randomized, double-blind clinical trial evaluating whether intraoperative intravenous lidocaine infusion (IVLI) reduces opioid requirements and improves postoperative pain control in children…
- Conditions
- Fracture Arm, Fracture Closed of Lower End of Forearm, Unspecified, Fracture Elbow, Fracture Fixation
- Trial name
- NCT07552766
- Testing
- Lidocaine Infusion, Standard of Care (SOC)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Nemours Children's Clinic
Postoperative Pain, Renal Transplantation
Intravenous Lignocaine Infusion in Laparoscopic Donor Nephrectomy
Background: Administration of morphine as boluses or via a patient controlled analgesic device (PCA) has been the standard practice for donors after nephrectomy.
- Conditions
- Postoperative Pain, Renal Transplantation, Morphine Adverse Reaction
- Trial name
- NCT04052867
- Testing
- Lignocaine, Normal saline
- Where
- Malaysia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Hysteroscopy
The Effect of Intrauterine Lidocaine Infusion and Oral Tramadol on Pain During Diagnostic Office Hysteroscopy
The purpose of this study is to compare the effectiveness of Tramadol and intrauterine lidocaine infusion in reducing pain during outpatient diagnostic hysteroscopy in postmenopausal women.
- Trial name
- NCT03701984
- Testing
- Lidocaine, Tramadol
- Where
- Egypt
- Volunteers
- 156 people
- Sponsor
- Cairo University
Breast Hypertrophy
ESPB Versus Intravenous Lidocaine for Pain After Mastopexy
Elective breast reduction surgery is associated with moderate-to-severe postoperative pain and a risk of developing chronic postsurgical pain.
- Trial name
- NCT07687069
- Testing
- Ultrasound - guided Erector Spine Plane Block (ESPB), Intraoperative intravenous lidocaine infusion
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Centre of Postgraduate Medical Education
Colorectal Cancer
Effect of Lidocaine on Postoperative Pain in Elderlypatients Undergoing Colorectal Cancer Surgery
Patients who meet the enrollment criteria will be randomized 1:1 to the lidocaine group or placebo group.
- Trial name
- NCT05920980
- Testing
- lidocaine
- Where
- China
- Volunteers
- 276 people
- Sponsor
- West China Hospital
Pain
4% Intrauterine Lidocaine Infusion for Pain Management in First Trimester Abortions
Recent studies have investigated the use of local anesthetics (i.e. lidocaine, mepivacaine) to lessen the pain experienced with minor gynecologic procedures such as endometrial biopsy and office hysteroscopy.
- Trial name
- NCT00121329
- Testing
- Intrauterine lidocaine infusion 4%
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Pain, Postoperative
Effect of Perioperative Intravenous Lidocaine on Opioid Consumption and Pain After Laparoscopic Totally Extraperitoneal Inguinal Hernioplasty
The primary objectives of this study is to access the effect of perioperative lidocaine infusion on total morphine requirement during the first 24 h postoperatively in patients who underwent laparoscopic totally extraperitoneal…
- Trial name
- NCT02601651
- Testing
- Lidocaine, Normal saline
- Where
- Nepal
- Volunteers
- 64 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Bier Block, Hand Surgery
Comparison Between Effect of Systemic Fentanyl Infusion and Fentanyl Added as An Adjuvant to Lidocaine in Bier Block For Controlling Pain in Patients Undergoing Hand Surgeries
Injury and deformity of the upper extremity can result in dysfunction to nerves, tendons and bones which can lead to disability and pain. Various techniques of regional anesthesia are frequently used for upper extremity surgery.
- Trial name
- NCT06696586
- Testing
- Fentanyl infusion, Fentanyl Injection
- Volunteers
- 84 people
- Sponsor
- Assiut University
Malignant Bowel Obstruction, Cancer Pain
Lidocaine Infusions for Pain in Patients With Malignant Bowel Obstruction
Malignant bowel obstruction is a frequent complication of advanced cancer, particularly of abdominal and pelvic origin, and most affected patients experience pain.
- Conditions
- Malignant Bowel Obstruction, Cancer Pain, Intestinal Obstruction
- Trial name
- NCT07856251
- Testing
- Lidocaine
- Volunteers
- 50 people
- Sponsor
- Fundación Santa Fe de Bogota
Cancer, Breast
Serum Opiorphin Level After Intraoperative Intravenous Lidocaine Infusion
A prospective, double blinded and randomized study included women with breast cancer and underwent mastectomy, and randomly allocated into two groups of equal size. Lidocaine group and control group.
- Trial name
- NCT03502395
- Testing
- Lidocaine, Normal saline
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Rib Fractures
Continuous Intravenous Lidocaine Infusion Versus Placebo for Rib Fracture Analgesia
The current cornerstone of pain control for rib fractures is oral and intravenous opioids, especially in the form of patient-controlled analgesia (IV PCA), which are are associated with multiple adverse effects including…
- Trial name
- NCT04140396
- Testing
- Saline infusion, Lidocaine infusion
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Stanford University