Clinical trials: Life Style, open to volunteers
Chronic Orofacial Pain, Temporomandibular Disorder (TMD)
Orofacial Pain Self-management: Personality Moderation Effect
The objective of this clinical trial is to study the effect of self-management on pain perception in patients with chronic orofacial pain and temporomandibular disorders (TMD) comparing it with the conventional treatment proposed…
- Conditions
- Chronic Orofacial Pain, Temporomandibular Disorder (TMD), Temporomandibular Disorders (TMD), Temporomandibular Dysfunction (TMD)
- Trial name
- NCT06932406
- Testing
- Self-management intervention, Clinical Practice Guideline Intervention
- Where
- Spain
- Volunteers
- 98 people
- Sponsor
- Fundación Universidad Católica de Valencia San Vicente Mártir
Cardiovascular Diseases (CVD)
Data Donation Model for Inclusive Cardiovascular Prevention Using the TRAIN Health Platform
Cardiovascular disease (CVD) is the leading cause of death in the Netherlands and worldwide. While prevention strategies have improved, many population groups, including women, individuals with a migration background, and people…
- Trial name
- DDM-TRAIN (NCT07238036)
- Testing
- Digital Lifestyle Feedback Module (optional)
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Acute Coronary Syndrome, Online CBT Targeting Cardiac Anxiety
Internet-based Behavioral Intervention Following ACS
The aim of this study is to evaluate if an online Cognitive Behavioral Therapy (CBT) protocol customized for patients following Acute Coronary Syndrome (ACS), reduce cardiac anxiety, enhance Quality of Life (QoL), and promote…
- Trial name
- ACS-CBT (NCT06298864)
- Testing
- Internet-CBT, Internet-CL
- Where
- Sweden
- Volunteers
- 176 people
- Sponsor
- Karolinska Institutet
Obesity & Overweight
Transcutaneous Auricular Vagus Nerve Stimulation for Poor Weight-Loss Response to Lifestyle Intervention
This single-center, randomized, single-blind, sham-controlled pilot study aims to evaluate the adjunctive effect of transcutaneous auricular vagus nerve stimulation (taVNS) in overweight/obese patients who show a poor weight loss…
- Trial name
- NCT07630597
- Testing
- transcutaneous auricular vagus nerve stimulation
- Where
- China
- Volunteers
- 24 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Major Depressive Disorder (MDD)
Implementation of a Multiple Intervention to Promote Healthy Lifestyles in Patients With Depression
This clinical trial aims to investigate whether an integrative approach combining education on the Mediterranean diet and physical activity (PA) can significantly reduce depressive symptomatology in individuals with major…
- Trial name
- NCT06990035
- Testing
- Mediterranean diet lessons program, Physical activity
- Where
- 2 sites in Italy
- Volunteers
- 120 people
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
OSA - Obstructive Sleep Apnea
Effect of Weight Loss From ESG Plus Lifestyle Changes vs. Lifestyle Changes Alone in Sleep Apnea Patients
Study Overview: Obesity and Obstructive Sleep Apnea (OSA) are strongly linked. This study aims to understand whether a procedure called Endoscopic Sleeve Gastroplasty (ESG), along with lifestyle changes like healthy eating and…
- Trial name
- OSA (NCT07082608)
- Testing
- Endoscopic Sleeve Gastropathy, Lifestyle Modification alone
- Where
- India
- Volunteers
- 74 people
- Sponsor
- Asian Institute of Gastroenterology, India
Breast Neoplasm
Improving Lifestyle Behavior by "Joven, Fuerte y Saludable" Multidisciplinary Program.
Breast cancer is the leading cause of mortality in women worldwide. Latin-American women are diagnosed at younger ages, in advanced stages, and with aggressive molecular subtypes.
- Trial name
- NCT06090747
- Testing
- Hybrid lifestyle educational multidisciplinary intervention., Hybrid lifestyle personalized multidisciplinary intervention.
- Where
- Mexico
- Volunteers
- 146 people
- Sponsor
- Instituto Nacional de Cancerologia de Mexico
Serious Mental Illness, Older Adults
A Pilot Randomized Controlled Trial of the Hopeful and Healthy Living Program
The goal of this clinical trial is to learn if a novel psychosocial intervention is effective in helping adults over 50 with serious mental illness (SMI) increase their social connections and participate in more healthy lifestyle…
- Trial name
- (HHL) (NCT06940843)
- Testing
- Hopeful and Healthy Living (HHL)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Boston University Charles River Campus
Mobile Health Apps, Lifestyle Intervention
Effectiveness of an AI-Enabled Mobile Intervention on Lifestyle Behaviors and Maternal-Infant Health
The goal of this pragmatic randomized controlled trial is to evaluate the effectiveness of an AI-enabled mobile health management application ("Better Pregnancy" app), grounded in the Theory of Planned Behavior, in preventing…
- Conditions
- Mobile Health Apps, Lifestyle Intervention, Prevention, Multi-component Based Behavioral Intervention
- Trial name
- NCT07582068
- Testing
- Multi-component lifestyle intervention
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao
Triple Negative Breast Cancer (TNBC), Early Setting
LifEStyle Intervention to Enhance Efficacy of Neoadjuvant Therapy in Patients With Triple Negative Breast Cancer
LESLIE is a multicentric randomized controlled trial in patients with triple negative breast cancer receiving neoadjuvant chemo/immunotherapy (NAT).
- Trial name
- LESLIE (NCT06831955)
- Testing
- Exercise Therapy, Fasting-Mimicking Diet, SOC
- Where
- 10 sites in Belgium
- Volunteers
- 356 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Subjective Cognitive Decline (SCD)
PENSA+: Extended Follow-up of a Multimodal Lifestyle Intervention to Prevent Cognitive Decline in APOE-ε4 Carriers
PENSA+ is a 5-year follow-up study of participants who previously completed the PENSA clinical trial (NCT03978052), which evaluated an intensive multimodal lifestyle intervention, with or without epigallocatechin gallate (EGCG)…
- Trial name
- PENSA+ (NCT07730671)
- Where
- Spain
- Volunteers
- 121 people
- Sponsor
- Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
Inactivity, Physical, Lifestyle Risk Reduction
Effects of a Lifestyle and Sleep Intervention in Non-exercising Adults
Background. Cardiovascular diseases (CVDs) are the leading cause of premature mortality and disability accounting for one third of all deaths worldwide with considerable impacts on economics and on quality of life.
- Trial name
- SPIRAL+ (NCT06424847)
- Testing
- Lifestyle intervention (physical activity and diet), Lifestyle (physical activity and diet) and Sleep intervention, Health education intervention
- Where
- France
- Volunteers
- 201 people
- Sponsor
- University Hospital, Grenoble
Diabetes Mellitus, Gestational Diabetes Mellitus (GDM)
Lifestyle Interventions to Prevent Diabetes in U.S. Home Visiting Programs
The study is examining the health effects of gestational diabetes mellitus (GDM) intervention and medically tailored meals within home visiting.
- Trial name
- NCT06988306
- Testing
- GDM Enhanced, Meals
- Where
- 3 sites in United States
- Volunteers
- 978 people
- Sponsor
- California Polytechnic State University-San Luis Obispo
Endometriosis, Pain
The Effect of an App-based Intervention on Quality of Life in Patients With Endometriosis.
The goal of this clinical trial is to learn if an App-based intervention affects the quality of life in patients with suspected or confirmed endometriosis.
- Conditions
- Endometriosis, Pain, Quality of Life, Life Style
- Trial name
- MASQUE (NCT06821217)
- Testing
- NALU Endo Flow App
- Where
- Switzerland
- Volunteers
- 308 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Type 2 Diabetes
The Impact of Diabetes Remission on Aging
This study is a real-world, prospective clinical cohort study. It will enroll Chinese patients with type 2 diabetes. The aim is to assess the changes in aging biomarkers, primarily DunedinPACE, from baseline to post-remission…
- Trial name
- NCT07736040
- Testing
- Comprehensive Lifestyle Intervention
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Overweight or Obesity, Pregnancy Related
Better Lifestyle Counseling for African American Women During Pregnancy
The purpose of this randomized controlled trial is to establish the effectiveness of a culturally targeted and individually tailored behavioral intervention to promote maternal glucose metabolism in African American women.
- Conditions
- Overweight or Obesity, Pregnancy Related, Sleep Disturbances, Sleep Hygiene
- Trial name
- BETTER (NCT05234125)
- Testing
- Better, Birth Prep
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of Illinois Chicago
Healthy
Lycopene as a Dietary Compliance Biomarker
Rationale: To determine the plasma lycopene concentration before and after an oral intake of lycopene in order to use this measurement as a life style compliance marker.
- Trial name
- NCT07117110
- Testing
- Supplement, Tomato soup
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Kidney Transplant, Overweight or Obese Adults
Feasibility and Plausible Effectiveness of a Lifestyle Intervention in Kidney Transplant Recipients (HEAL)
The goal of this clinical trial is to learn whether if it is feasible to implement a study of patients receiving kidney transplantation, to learn if these patients will complete selective outcomes measurements, and to examine if…
- Conditions
- Kidney Transplant, Overweight or Obese Adults, Glucose Control
- Trial name
- HEAL (NCT06640179)
- Testing
- Standard medical care, Monitoring Contacts, Behavioral Sessions
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Kansas Medical Center
Overweight, Children
010Fit'R - Healthy Lifestyle Interventions for Children With Overweight
Overweight is a leading risk factor for non-communicable diseases. In the Netherlands, about 11% of children aged 4-12 years are overweight.
- Trial name
- 010Fit'R (NCT07419503)
- Testing
- 010 Fit'R intervention
- Where
- Netherlands
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Obesity & Overweight, Obesity (Disorder)
Examining Valence-based Effects in Self-Monitoring Feedback Messages
The purpose of this research study is to learn how to identify the most effective ways to provide weekly feedback on participants' progress toward intervention goals during a weight loss program.
- Trial name
- NCT07292389
- Testing
- Positive Reinforcement, Positive Reinforcement + Areas for Change
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- University of Virginia