Clinical trials: Lifestyle Modification
Obesity, Diabetes Mellitus
Incentivizing Lifestyle Modification to Reduce Disease Burden
Specifically, the main objective of this pilot and feasibility study is to develop the infrastructure that will be used in a larger study that would be proposed at a later date. Hence, this study has two parts.
- Trial name
- NCT02945332
- Testing
- Required supervised walking, Non-required supervised walking, Fitbit Flex
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Type 2 Diabetes
The Impact of Diabetes Remission on Aging
This study is a real-world, prospective clinical cohort study. It will enroll Chinese patients with type 2 diabetes. The aim is to assess the changes in aging biomarkers, primarily DunedinPACE, from baseline to post-remission…
- Trial name
- NCT07736040
- Testing
- Comprehensive Lifestyle Intervention
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Overweight, Obesity
Electrical Vestibular Nerve Stimulation (VeNS) Compared to Sham Control as a Means of Reducing Excess Body Weight
A randomized, double blind sham controlled clinical trial to evaluate the efficacy of vestibular nerve stimulation (VeNS), together with a lifestyle modification program, compared to a sham control with a lifestyle modification…
- Conditions
- Overweight, Obesity, Overweight and Obesity, Overweight or Obesity
- Trial name
- NCT04110717
- Testing
- Vestal Device, Control Device, Hypocaloric Diet
- Where
- Ireland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Neurovalens Ltd.
Healthy Lifestyle
A Pilot Randomized Controlled Trial of Chatbot Use in Older Adults for Lifestyle Change
The purpose of this study is to evaluate the acceptability and preliminary effectiveness of a smartphone-delivered AI-based chatbot in promoting healthy dietary behavior and physical activity participation among older adults.
- Trial name
- NCT06901037
- Testing
- A chatbot-based intervention
- Where
- Hong Kong
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Breast Cancer, Weight Loss
Low Fat Versus Protein Sparing Diet for Weight Loss & Impact on Biomarkers Associated With Breast Cancer Risk
The primary specific aim of this study was to determine if overweight and obese premenopausal women can lose weight and if long term weight loss impacts biomarkers associated with breast cancer risk.
- Trial name
- LEAF (NCT01559194)
- Testing
- Low Fat Diet plus exercise, Low Carbohydrate diet + Exercise
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Pain, Osteoarthritis
Improvement of a Physically Active Lifestyle
To help rehabilitation patients to adopt and maintain a physically active lifestyle, it is imperative to increase self-management competencies.
- Conditions
- Pain, Osteoarthritis, Rheumatoid Arthritis, Heart Diseases
- Trial name
- FaBA (NCT00979719)
- Testing
- Intervention Group (IG), Active Control Group (ACG)
- Where
- Germany
- Volunteers
- 1,377 people, healthy volunteers welcome
- Sponsor
- Freie Universität Berlin
Healthy
A Study Investigating the Effectiveness of a LifeSeasons NeuroQ Supplement With Lifestyle Changes to Improve Cognitive Function in Healthy Adults Who Have One or More Risk Factors for Cognitive Decline
The objective of this study is to evaluate the efficacy of a NeuroQ supplement designed by Dr. Bredesen to complement his Lifestyle modification protocol.
- Trial name
- NCT04149639
- Testing
- NeuroQ
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- LifeSeasons Inc.
Ageing
Association of Midlife Dietary and Lifestyle Factors on Cardiac Functional Changes in the Elderly
The investigators aim to investigate the association of midlife dietary and lifestyle factors on cardiac functional changes in the elderly.
- Trial name
- CardiacAging (NCT02791139)
- Testing
- Cardiovascular Magnetic Resonance Imaging (MRI), Echocardiography, Tonometry
- Where
- Singapore
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- National Heart Centre Singapore
Breast Cancer Prevention
MELIORA Data Collection Campaigns
To support the development of the MELIORA digital app for the MELIORA main intervention, an initial pilot study (Data Collection Campaign, DCC) is being conducted with the three target participant groups: healthy women at…
- Trial name
- DCC (NCT07190066)
- Testing
- Data Collection campaign
- Where
- 7 sites in Greece, Lithuania and 2 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Obesity
The AUDACITY Study (AllUrion Device in Adults With Clinical ObesITY)
The objective for this clinical study is to provide FDA with clinical evidence regarding the effectiveness and safety of the AGBS + moderate intensity lifestyle modification therapy program, indwell time of the AGBS inside the…
- Trial name
- AUDACITY (NCT05368259)
- Testing
- AGBS
- Where
- 17 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Allurion Technologies
Myocardial Infarction
The Effect of Education and Telephone Follow-up Intervention Based on the Roy Adaptation Model
In this parallel randomized controlled trial (n = 33/group), the control group received routine care, while the intervention group received a telephone follow-up intervention, which consisted of a pre-discharge education program…
- Trial name
- NCT03771937
- Testing
- Education and telephone follow-up intervention
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Men, Diet Modification
Dietary Guide in Active Older Adult Men
The present study aimed to determine the effects of negative-calorie diet supplemented with exercise, on weight loss and lipid profile, and to compare its efficiency with low-calorie diet with exercise among elderly adult men…
- Conditions
- Men, Diet Modification, Obesity, Overweight
- Trial name
- NCT03082807
- Testing
- NCDsport, LCDsport
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- P.L.Shupik National Medical Academy of Post-Graduate Education
Alzheimer Disease
A Study on the Effectiveness of Multidomain Intervention Program for Reducing Risks of Dementia
Investigators aimed to examine the feasibility and effectiveness of a multidomain intervention strategy involving intensive and maintenance programs aimed at reducing the risk of Alzheimer's disease (AD) in at-risk older adults.
- Trial name
- NCT03786510
- Testing
- Active control, Intensive + Maintenance program, Intensive program only
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Sedentary Lifestyle, Self-control
Testing Self-Control as a Behavior Change Mechanism to Increase Physical Activity
The goal of this study is to test self-control as a behavior change mechanism for physical activity and to investigate whether a smartphone-based self-control intervention can increase physical activity among sedentary…
- Trial name
- NCT04522141
- Testing
- Self-control intervention, Control condition
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Brandeis University
Overweight, Weight Loss
Healthy Eating, Activity, & Lifestyle Training Headquarters: II Pilot Project
The proposed study aims to combine evidenced based tools and guidance (H.E.A.L.T.H.: Healthy Eating Activity Lifestyle Training Headquarters) previously tested that has been developed specifically for use by Army Soldiers and a…
- Trial name
- NCT02905422
- Testing
- H.E.A.L.T.H. II Intervention
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Obesity
Adapted Cognitive Behavioral Approach to Addressing Overweight and Obesity Among Qatari Youth
Levels of overweight and obesity have reached alarming proportions in Qatar and other Gulf nations. In Qatar, the need to establish national strategies for the prevention and treatment of obesity has been recognized in the new…
- Trial name
- NCT02972164
- Testing
- Weight loss program for school children
- Where
- Qatar
- Volunteers
- 799 people, healthy volunteers welcome
- Sponsor
- Qatar University
Cancer Prevention
Cancer Literacy as an Essential Factor for Lifestyle Behavior Changes: An Observational and Interventional Study
The CLARO study aims to examine the most effective way to design information materials that can strengthen optimistic beliefs about cancer prevention and improve cancer literacy indirectly.
- Trial name
- CLARO (NCT06614673)
- Testing
- text in non-narrative form, text in narrative form, animated video in non-narrative form
- Where
- Germany
- Volunteers
- 1,422 people, healthy volunteers welcome
- Sponsor
- German Cancer Research Center
Behavior Change Interventions, Cardiovascular Diseases
Primary Care - Prescribing Lifestyle Adjustments for Cardiovascular Health
Prescribing lifestyle changes to patients who are at risk of cardiovascular disease, may be an extremely cost effective mechanism of improving health for the individual themselves and the NHS.
- Conditions
- Behavior Change Interventions, Cardiovascular Diseases, Cardiovascular Risk Factor, Behavior, Health
- Trial name
- P-PLAC 2 (NCT04113213)
- Testing
- Lifestyle Prescription (LRx)
- Where
- United Kingdom
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of South Wales
Sedentary Lifestyle
The Health Action Process Approach and Movement Patterns in Adult Office Workers
Societal changes have resulted in reduced demands to be active and increased daily time spent sitting. Excessive sitting has been shown to be a health hazard.
- Trial name
- NCT03091686
- Testing
- HAPA SB Intervention Slideshow, HAPA MVPA Attention-Control Slideshow
- Where
- Canada
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Obesity, Morbid
Suboptimal Weight Loss After Gastric Bypass Surgery
Bariatric surgery is the only long-term established treatment for morbid obesity. However, some patients experience suboptimal weight loss after surgery and/or experience a significant weight regain.
- Trial name
- NCT01829906
- Testing
- Multidisciplinary outpatient programme, Inpatient lifestyle programme
- Where
- Norway
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology