Clinical trials: Lifestyle Modification
Sedentary Lifestyle, Self-control
Testing Self-Control as a Behavior Change Mechanism to Increase Physical Activity
The goal of this study is to test self-control as a behavior change mechanism for physical activity and to investigate whether a smartphone-based self-control intervention can increase physical activity among sedentary…
- Trial name
- NCT04522141
- Testing
- Self-control intervention, Control condition
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Brandeis University
Obesity, Sedentary Lifestyle
Exercise After Clinically Significant Weight Loss
The Prescribed Exercise to Reduce Recidivism After Weight Loss Pilot (PREVAIL-P) study will evaluate the effect of aerobic exercise training amount on weight maintenance following clinically significant weight loss.
- Conditions
- Obesity, Sedentary Lifestyle, Insulin Resistance
- Trial name
- PREVAIL-P (NCT03685123)
- Testing
- Physical activity recommendations, Weight maintenance recommendations, OPTIFAST weight loss
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Healthy Lifestyle, Overweight
Deaf Weight Wise: Community-engaged Implementation Research to Promote Healthy Lifestyle Change With Deaf ASL Users
The purpose of the Deaf Weight Wise Implementation Study is to study with diverse partners the approaches and strategies that lead to successful implementation of Deaf Weight Wise (DWW), an evidence-based healthy lifestyle…
- Conditions
- Healthy Lifestyle, Overweight, Obesity, Cardiovascular Risks
- Trial name
- NCT05211596
- Testing
- Deaf Weight Wise intervention
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Chronic Pain, Obesity
A Mobile Intervention to Reduce Pain and Improve Health (MORPH)
Chronic pain contributes to declining health and function in older adults; effects that are intensified by obesity and sedentary (sitting) behavior.
- Conditions
- Chronic Pain, Obesity, Sedentary Lifestyle
- Trial name
- NCT03377634
- Testing
- MORPH
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Wake Forest University Health Sciences
PreDiabetes, Overweight and Obesity
Family Diabetes Prevention Program Pilot Study
This study will examine the feasibility and acceptability of a family-oriented augmentation of the Diabetes Prevention Program lifestyle intervention (DPP), called the Family DPP.
- Conditions
- PreDiabetes, Overweight and Obesity, Type 2 Diabetes, Overweight, Childhood
- Trial name
- NCT05358444
- Testing
- National Diabetes Prevention Program Lifestyle Intervention (DPP), Family Diabetes Prevention Program (Family DPP)
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Diabetes
Enhanced DPP-GLB to Promote Weight Loss Among Nonresponders in a Community-Based Lifestyle Intervention.
This study seeks to establish the efficacy of identifying weight loss nonresponders early in a Diabetes Prevention Program (DPP) intervention in 20 community settings (primarily churches and community centers) and providing them…
- Trial name
- NCT04757519
- Testing
- DPP-GLB Standard, DPP-GLB Enhanced
- Where
- 21 sites in United States
- Volunteers
- 403 people, healthy volunteers welcome
- Sponsor
- Lovoria Williams
Obesity, Diabetes Mellitus
Incentivizing Lifestyle Modification to Reduce Disease Burden
Specifically, the main objective of this pilot and feasibility study is to develop the infrastructure that will be used in a larger study that would be proposed at a later date. Hence, this study has two parts.
- Trial name
- NCT02945332
- Testing
- Required supervised walking, Non-required supervised walking, Fitbit Flex
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Obesity
Lifestyle Modification and Lorcaserin for Weight Loss Maintenance
The proposed 12-month randomized controlled trial will assess the efficacy of lifestyle counseling, combined with lorcaserin (10 mg BID) or placebo, in maintaining weight loss achieved during a prior 14-week dietary run-in.
- Trial name
- NCT02388568
- Testing
- Lorcaserin
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- University of Pennsylvania
Sedentary Lifestyle, Stress, Psychological
Development of An Exergame for Caregivers of Individuals With Alzheimer's Disease or Related Dementias
The study goal is to evaluate user experience with our developed exergame, which was designed to increase physical activity, exercise self-efficacy, and social connections among caregivers of individuals with Alzheimer's disease…
- Trial name
- NCT03124550
- Testing
- Exergame Experience
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Brandeis University
Diabetes, Myocardial Infarction
Look AHEAD: Action for Health in Diabetes
The Look AHEAD study is a multi-center, randomized clinical trial to examine the long-term effects of a lifestyle intervention designed to achieve and maintain weight loss.
- Conditions
- Diabetes, Myocardial Infarction, Stroke, Kidney Diseases
- Trial name
- LookAHEAD (NCT00017953)
- Testing
- Lifestyle Intervention, Diabetes Support and Education
- Where
- 18 sites in United States
- Volunteers
- 5,145 people
- Sponsor
- Wake Forest University Health Sciences
Obesity
DVD Lifestyle Intervention
Most Veterans who receive VA healthcare have obesity (41%) or are classified as overweight (37%), putting them at higher risk for multiple serious chronic health conditions.
- Trial name
- D-ELITE (NCT03260140)
- Testing
- behavioral lifestyle intervention
- Where
- United States
- Volunteers
- 511 people
- Sponsor
- VA Office of Research and Development
Depression, Obesity
Research Aimed at Improving Both Mood and Weight
The RAINBOW study is an NIH R01-funded randomized controlled trial to evaluate the clinical and cost effectiveness and implementation potential of a primary care integrated multicondition intervention program to help improve mood…
- Trial name
- RAINBOW-ENGAGE (NCT02246413)
- Testing
- RAINBOW Intervention Program
- Where
- 2 sites in United States
- Volunteers
- 409 people
- Sponsor
- Palo Alto Medical Foundation
Behavioral / Psychiatric Disorder, Lifestyle, Healthy
Promoting Healthy Lifestyle Behaviors
This study's purpose is to identify factors that may aid in answering the clinical question: Among adolescents 12-17 years old who are diagnosed with a mental health condition(s), does a family-based educational intervention…
- Trial name
- NCT05675020
- Testing
- Zoom Intervention
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Florida State University
Type 2 Diabetes Mellitus
Safety and Efficacy of Exenatide Once Weekly Versus Liraglutide in Subjects With Type 2 Diabetes
No head to head comparisons between exenatide once weekly and liraglutide have been performed. Therefore, the purpose of this study is to compare exenatide once weekly to once-daily liraglutide with regard to HbA1c, body weight…
- Trial name
- NCT01029886
- Testing
- exenatide once weekly, liraglutide
- Where
- 108 sites in Argentina, Australia and 19 more
- Volunteers
- 912 people
- Sponsor
- AstraZeneca
Obesity
Semaglutide Treatment, Appetite, and Eating Behavior: Long-term Effects
This study will evaluate the effect of semaglutide on eating behavior, appetite (hunger/fullness), and food liking in the long-term, as compared to placebo.
- Trial name
- STABLE Wt Loss (NCT05548647)
- Testing
- Behavioral Treatment, Semaglutide 2.4 MG/0.75 ML Subcutaneous Solution [WEGOVY]
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Pennsylvania
Accidental Fall
Adapted Lifestyle-integrated Functional Exercise Program for Medically Underserved Older Adults
This study will test the feasibility of a study design for the Adapted Lifestyle-integrated Functional Exercise (LiFE) program for medically underserved older adults and to explore factors related to implementation.
- Trial name
- LiFE (NCT03704194)
- Testing
- Adapted LiFE, Attention control
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obesity, Weight Loss
Empowered With Movement to Prevent Obesity and Weight Regain
This study will help determine the appropriate type, amount and intensity of physical activity most beneficial for preventing weight regain after weight loss in older adults.
- Conditions
- Obesity, Weight Loss, Sedentary Lifestyle
- Trial name
- EMPOWER (NCT02923674)
- Testing
- Weight loss, Exercise, Sitless
- Where
- United States
- Volunteers
- 183 people
- Sponsor
- Wake Forest University Health Sciences
Type 2 Diabetes Mellitus
Effect on Weight Loss of Exenatide Versus Placebo
This trial is designed to compare the effects of twice-daily exenatide and twice-daily placebo on weight loss. This trial will evaluate overweight and obese subjects with type 2 diabetes who have inadequate glycemic control with…
- Trial name
- NCT00375492
- Testing
- exenatide
- Where
- 10 sites in United States
- Volunteers
- 196 people
- Sponsor
- AstraZeneca
Gestational Weight Gain
A Mobile Health Intervention to Achieve Appropriate Gestational Weight Gain in Overweight/Obese Women
The aim of this trial is to investigate the effectiveness of a mobile health (mhealth) intervention to help overweight and obese women achieve appropriate gestational weight gain (GWG) for their pre-pregnancy body mass index…
- Trial name
- NCT03880461
- Testing
- Lifestyle Intervention
- Where
- 4 sites in United States
- Volunteers
- 1,335 people
- Sponsor
- Kaiser Permanente
Obesity
Pivotal Aspiration Therapy With Adjusted Lifestyle Therapy Study
This research study is being performed to find out if a new device, AspireAssist Aspiration Therapy System, can help people with obesity to lose weight without causing too many side effects.
- Trial name
- PATHWAY (NCT01766037)
- Testing
- Aspiration Therapy (AspireAssist), Lifestyle Therapy
- Where
- 10 sites in United States
- Volunteers
- 171 people
- Sponsor
- Aspire Bariatrics, Inc.