Clinical trials: Lifestyle Modification
Obesity
Pivotal Aspiration Therapy With Adjusted Lifestyle Therapy Study
This research study is being performed to find out if a new device, AspireAssist Aspiration Therapy System, can help people with obesity to lose weight without causing too many side effects.
- Trial name
- PATHWAY (NCT01766037)
- Testing
- Aspiration Therapy (AspireAssist), Lifestyle Therapy
- Where
- 10 sites in United States
- Volunteers
- 171 people
- Sponsor
- Aspire Bariatrics, Inc.
Type 2 Diabetes
Application and Effectiveness Analysis of Internet-based Diabetes Prevention Program
This study was conducted to test the possibility of preventing or delaying the development of type 2 diabetes in individuals with impaired glucose tolerance and elevated fasting plasma glucose concentrations by internet-based…
- Trial name
- NCT01085682
- Testing
- Lifestyle counseling, Standard care
- Where
- South Korea
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Pediatric Obesity, Weight Loss
Our Lifestyles Our Lives
The purpose of the study was to examine the influence of step goals with pedometers to improve children's weight loss, physical activity, and psychosocial health during behavioral treatment.
- Trial name
- OLOL (NCT02965729)
- Testing
- Family-based weight management, Pedometer, Individualized step goals
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Hypertension, Pulmonary
Study of a New Thermo Stable Formulation of Epoprostenol Sodium to Treat Pulmonary Arterial Hypertension (PAH)
The purpose of this multicentre, open label, single-arm study in approximately 20 adult patients is to evaluate the Impact on lifestyle of a new thermo stable formulation of epoprostenol sodium in subjects with Pulmonary Arterial…
- Trial name
- NCT01462565
- Testing
- current marketed FLOLAN (epoprostenol sodium), new thermo stable formulation of epoprostenol sodium
- Where
- 8 sites in United States, Canada and 1 more
- Volunteers
- 16 people
- Sponsor
- GlaxoSmithKline
Overweight, Obesity
Sharing Digital Self-Monitoring Data With Others to Enhance Long-Term Weight Loss
Adults attempting weight loss through lifestyle modification (LM) typically find maintenance of behavior change difficult. Outcomes might be improved if participants are provided with sustained sources of accountability and…
- Trial name
- FitLink (NCT05180448)
- Testing
- Coach Share On, Group Share On, Friend/Family Share On
- Where
- United States
- Volunteers
- 321 people, healthy volunteers welcome
- Sponsor
- Drexel University
Obesity
Lifestyle Modification and Liraglutide
This is a 52 week, single center, open-labeled, randomized controlled trial. A total of 150 subjects with obesity, who are free of types 1 and 2 diabetes, as well as contraindications to weight loss, will be randomly assigned to…
- Trial name
- MODEL (NCT02911818)
- Testing
- CMS-recommended lifestyle counseling, Liraglutide 3.0mg, Portion-Controlled Diet
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Pennsylvania
Chronic Kidney Diseases
Digital Dyadic Empowerment Program on Lifestyle Modification for Chronic Kidney Disease Management
The goal of this clinical trial is to find out if the Digital Dyadic Empowerment Program (DDEP) can help people with chronic kidney disease (CKD) and their care partners make healthy lifestyle changes.
- Trial name
- DDEP (NCT06756113)
- Testing
- Digital Dyadic Empowerment, Usual Care
- Where
- Taiwan
- Volunteers
- 208 people
- Sponsor
- National Cheng Kung University
Diet Modification, Substance Use Disorders
The Impact of a Parenting Intervention on Latino Youth Health Behaviors
The purpose of this study is to test if a parenting program can be used to prevent substance use among Latino youth and at the same time promote healthy eating.
- Conditions
- Diet Modification, Substance Use Disorders, Diabetes Mellitus Risk, Cardiovascular Risk Factor
- Trial name
- FPNG+ (NCT03517111)
- Testing
- Nutrition/substance use prevention, Substance use prevention only, Academic success program
- Where
- United States
- Volunteers
- 844 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Depression, Obesity
Research Aimed at Improving Both Mood and Weight
The RAINBOW study is an NIH R01-funded randomized controlled trial to evaluate the clinical and cost effectiveness and implementation potential of a primary care integrated multicondition intervention program to help improve mood…
- Trial name
- RAINBOW-ENGAGE (NCT02246413)
- Testing
- RAINBOW Intervention Program
- Where
- 2 sites in United States
- Volunteers
- 409 people
- Sponsor
- Palo Alto Medical Foundation
Pediatric Obesity
Quincy Family, Youth & Technology For Lifestyle Change (FYT-4-LIFE) Study
To date, approaches that show the most promise for preventing and/or reversing the course of childhood obesity involve the delivery of intensive lifestyle interventions within a family-based context, emphasizing the necessity of…
- Trial name
- QFYT (NCT02324361)
- Testing
- Physical Activity, Evidence-based information on healthy family routines
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Asthma
Pilot of Lifestyle and Asthma Intervention
This is to pilot test a weight loss intervention in obese patients with poorly controlled asthma. Obesity is a risk factor for the development of asthma (approximately 250,000 cases per year of asthma in the U.S.
- Trial name
- PLAN (NCT03291808)
- Testing
- Weight loss intervention
- Where
- 2 sites in United States
- Volunteers
- 43 people
- Sponsor
- Johns Hopkins University
Obesity, Diabetes Mellitus
Incentivizing Lifestyle Modification to Reduce Disease Burden
Specifically, the main objective of this pilot and feasibility study is to develop the infrastructure that will be used in a larger study that would be proposed at a later date. Hence, this study has two parts.
- Trial name
- NCT02945332
- Testing
- Required supervised walking, Non-required supervised walking, Fitbit Flex
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Schizophrenia, Obesity
Lifestyle Intervention for Weight Gain Management for Patients With Schizophrenia
The aims of this study were to evaluate the efficacy of an intervention for weight gain management for patients from schizophrenia spectrum compared to treatment as usual (TAU), and to evaluate the effects of this program on…
- Trial name
- NCT01368406
- Testing
- wellness program
- Where
- 4 sites in Brazil
- Volunteers
- 160 people
- Sponsor
- Federal University of São Paulo
Maternal Obesity, Gestational Weight Gain
Lifestyle and Pregnancy: The Clinical Effect of Lifestyle Intervention During Pregnancy in Obese Women
Obesity is a serious and increasing health problem in the Western World with about one third of all pregnant women in Denmark being overweight. Among these are more than 11% severe obese.
- Conditions
- Maternal Obesity, Gestational Weight Gain, Obstetric Complications
- Trial name
- LiP (NCT00530439)
- Testing
- Lifestyle intervention, Control, Physical activity, dietetic counselling
- Where
- Denmark
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Sedentary Lifestyle, Stress, Psychological
Development of An Exergame for Caregivers of Individuals With Alzheimer's Disease or Related Dementias
The study goal is to evaluate user experience with our developed exergame, which was designed to increase physical activity, exercise self-efficacy, and social connections among caregivers of individuals with Alzheimer's disease…
- Trial name
- NCT03124550
- Testing
- Exergame Experience
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Brandeis University
Chronic Kidney Diseases
DDEP for Lifestyle Modification in Chronic Kidney Disease
This is a randomized controlled feasibility trial conducted on patients with Chronic Kidney Disease (CKD) and their significant other
- Trial name
- NCT06226649
- Testing
- Digital Dyadic Empowerment
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Cheng Kung University
PreDiabetes, Hyperglycemia
Effectiveness and Cost-Effectiveness of Fully-Automated Digital vs. Human Coach-Based Diabetes Prevention Programs
The purpose of this research study is to compare the effectiveness of a fully automated digital diabetes prevention program to standard of care human coach-based diabetes prevention programs for promoting clinically meaningful…
- Conditions
- PreDiabetes, Hyperglycemia, Glucose, High Blood, Overweight
- Trial name
- NCT05056376
- Testing
- Digital Diabetes Prevention Program (dDPP), Human Coach-based Diabetes Prevention Program (hDPP)
- Where
- 2 sites in United States
- Volunteers
- 368 people
- Sponsor
- Johns Hopkins University
Weight Loss
Opt-IN: Optimization of Remotely Delivered Intensive Lifestyle Treatment for Obesity
The overall objective of the proposed research is to use an innovative methodological framework, the Multiphase Optimization Strategy (MOST), to design, for the first time, an optimized, scalable version of a technology-supported…
- Trial name
- Opt-IN (NCT01814072)
- Testing
- 12 Telephone Coaching Sessions, 24 Telephone Coaching Sessions, Report to Primary Care Physician
- Where
- United States
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Obesity, Life Style
Intensive Lifestyle Interventions to Overweight and Obese Patients in Primary Care
The goal of this clinical trial is to compare in the effect of different lifestyle interventions in overweight and obese participants.
- Conditions
- Obesity, Life Style, Lifestyle, Sedentary
- Trial name
- NCT06321809
- Testing
- intensive lifestyle
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Duygu Ayhan Baser
Weight Loss, Pre Diabetes
Healthy Body Healthy Souls in the Marshallese Population
The primary aim is to pilot test a weight-loss intervention for Marshallese adults, referred to throughout as Healthy Bodies Healthy Souls (HBHS).
- Conditions
- Weight Loss, Pre Diabetes, Overweight and Obesity
- Trial name
- NCT03377244
- Testing
- HBHS, HBHS Policy, WORD DPP
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Arkansas