Clinical trials: Lifestyle-Related Disorder
Disruptive Mood Dysregulation Disorder, Attention Deficit Hyperactivity Disorder
Characterization and Brain Mechanisms of Frustration in Youth With Severe Irritability or Attention Deficit Hyperactivity Disorder (ADHD)
Background: Irritability is an elevated proneness to anger. Children with irritability have difficulty tolerating frustration. They get angry and have temper outbursts more easily than their others their age.
- Conditions
- Disruptive Mood Dysregulation Disorder, Attention Deficit Hyperactivity Disorder, Normal Physiology
- Trial name
- NCT05357495
- Testing
- Affective Posner fMRI frustration induction task
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Attention Deficit Hyperactivity Disorder
Safety and Efficacy of GTS21 in Adults With Attention-deficit Hyperactivity Disorder
This study will be a randomized, double-blind, placebo-controlled crossover study to assess the effects of GTS21 (25 mg three times a day (tid), 75 mg tid, 150 mg tid) compared to placebo in non-smoking adults aged 18-55 with a…
- Trial name
- NCT00419445
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- CoMentis
Attention Deficit Hyperactivity Disorder
PART B: Efficacy and Safety of AEVI-001 in Children and Adolescents With ADHD and Without mGluR Mutations
This is PART B of a 2-part, 6-week, double-blind, dose-optimization, parallel-group study in children and adolescents (ages 6-17 years) with ADHD with and without CNVs in specific genes implicated in glutamatergic signaling and…
- Trial name
- NCT03609619
- Testing
- AEVI-001
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Aevi Genomic Medicine, LLC, a Cerecor company
Attention-Deficit/Hyperactivity Disorder
Role of Circadian and Homeostatic Systems in the Regulation of Wakefulness in Adult Patients With Attention Deficit Disorder With or Without Hyperactivity
In a previous protocol, we highlighted an excessive daytime sleepiness at the Maintenance of Wakefulness Tests (MWT) in 36% of adult Attention Deficit Disorder with or without Hyperactivity (ADHD) patients.
- Trial name
- VEILLETDAH (NCT02217371)
- Testing
- Neuropsychological tests
- Where
- France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Attention-Deficit/Hyperactivity Disorder
Dose-optimization in Adolescents Aged 13-17 Diagnosed With Attention-deficit/Hyperactivity Disorder (ADHD) Using Extended-release Guanfacine HCl
To assess the efficacy of optimized Extended-release Guanfacine Hydrochloride compared with placebo in the treatment of adolescents aged 13-17 years with a diagnosis of ADHD as measured by the ADHD-RS-IV
- Trial name
- NCT01081132
- Testing
- Extended-release Guanfacine Hydrochloride
- Where
- 54 sites in United States
- Volunteers
- 314 people
- Sponsor
- Shire
Behavior Disorders
Remote Training in Rural Schools
Rural areas have fewer, and less well trained, health care providers than non-rural areas. Schools have become more involved in the delivery of mental health services and hold great potential for increasing access to children and…
- Trial name
- NCT05034198
- Testing
- Coping Power Program (CPP), Cognitive behavioral therapy (CBT) for Anxiety Treatment in Schools (CATS), Check-in/Check-out (CI/CO)
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Oppositional Defiant Disorder, Attention Deficit Hyperactivity Disorders
Guided Self-Help for Parents of Children With Externalizing Problem Behavior
The efficacy of cognitive-behavioral based guided self-help for parents of children with externalizing problem behavior is tested in a randomized clinical trial.
- Conditions
- Oppositional Defiant Disorder, Attention Deficit Hyperactivity Disorders, Attention Deficit and Disruptive Behavior Disorders
- Trial name
- FLOH (NCT01350986)
- Testing
- Cognitive-Behavioral Self-help Workbook + Counseling Telephone Calls, Non-Directive Self-Help Workbook + Counseling Telephone Calls
- Where
- Germany
- Volunteers
- 146 people
- Sponsor
- German Research Foundation
Attention Deficit Hyperactivity Disorder
Neurobiological Aspects of the Attention Deficit Hyperactivity Disorder
Evaluating neurobiological disorder associated with Attention Deficit Hyperactivity Disorder (ADHD) and the contribution of transcranial direct current stimulation (tDCS) in the adaptation of inhibitory control.
- Trial name
- NAADHD (NCT01968512)
- Testing
- Transcranial Direct Current Stimulation
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of Bahia
Sleep Problem, ADHD
Better Sleep in Psychiatric Care - ADHD.
Cognitive Behavioral Therapy (CBT) is treatment of choice for insomnia (CBT-i). Many patients in psychiatric care have sleep problems including insomnia, but are rarely given the choice to participate in CBT to improve their…
- Trial name
- BSIP-ADHD (NCT03015636)
- Testing
- Adjusted CBT-i for ADHD, Treatment as Usual
- Where
- Sweden
- Volunteers
- 58 people
- Sponsor
- Karolinska Institutet
Attention Deficit Hyperactivity Disorder (ADHD)
Access to Extended Release Guanfacine HCl for Subjects Who Participated in Studies SPD503-315 or SPD503-316 in Europe
For subjects in Europe that have already participated in either Study SPD503-315 or SPD503-316. This is an extension study that will allow participants access to Extended-release Guanfacine Hydrochloride (HCl) for up to 2 years.
- Trial name
- NCT01500694
- Testing
- Extended-release Guanfacine HCl (Intuniv, SPD503)
- Where
- 60 sites in Austria, Belgium and 11 more
- Volunteers
- 215 people
- Sponsor
- Shire
Autism Spectrum Disorder (ASD), Central Auditory Processing Disorder
Mental And Speech Developmental Delay Autism Spectrum-Type Behavioral Disorder
FAMILY SYSTEM CITADEL 2060.METHODOLOGY "VOICE OF SLEEP MAMABEE 2026-2085 Systemic work with brain neurons through training modules at the border of sleep in clinical, psychological and strategic logic.
- Conditions
- Autism Spectrum Disorder (ASD), Central Auditory Processing Disorder, Nervous System Disorder, Neurological Disorder
- Trial name
- NCT07670000
- Testing
- Audio fairy tales
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Natalia Poluektova
Attention Deficit-Hyperactivity Disorder
TLR Polymorphism, ASO and Beta-hemolytic Group A Streptococcus Infections in ADHD: an Observational Study
The aim of this observational cross-sectional study is to evaluate the streptococcal infection (clinical history, ASLO title and anti-DNAse title B) and autoimmunity (ABGA antibodies) in a sample of 100 adult patients diagnosed…
- Trial name
- TLR; (NCT04038073)
- Testing
- Antistreptolysin O Test, Anti-Deoxyribonuclease B, TLR, MyD88, IRAK-4 polymorphism
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Turin, Italy
Attention Deficit Hyperactivity Disorder (ADHD)
PRC-063 in an ADULT Workplace Environment
The primary objective of this study is to assess the time of onset and time course of efficacy over 16 hours of PRC-063 compared to placebo in adults diagnosed with ADHD in a simulated adult workplace environment (AWE) setting…
- Trial name
- NCT02225639
- Testing
- PRC-063 25 mg, PRC-063 35 mg, PRC-063 45 mg
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Rhodes Pharmaceuticals, L.P.
Sedation Complication
Comparison Between Intranasal vs Intravenous Dexmedetomidine for EEG Sedation of Children With Behavior Disorders.
The aim of the project was to compare the efficacy and safety of intranasal (IN) and intravenous (IV) dexmedetomidine (DEX) in procedural sedation for electroencephalogram (EEG) in pediatric patients with behavioural disorders.
- Trial name
- NCT06434428
- Testing
- dexmedetomidine (IV), dexmedetomidine (IN)
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- Azienda Ospedaliera di Padova
ADHD
Single-dose Potassium Supplementation in Patients With ADHD for Whom the Anesthetic Lidocaine is Ineffective
Randomized, controlled, double-blind trial of the effect of a single dose of potassium on ADHD symptoms as measured by changes in measures of symptoms of ADHD correlated with the results of their Lidocaine Effectiveness Test.
- Trial name
- NCT03563573
- Testing
- Potassium Gluconate Oral Capsule
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- AlkaliDx, Inc.
ADHD - Attention Deficit Disorder With Hyperactivity, Specific Learning Disorder
White Noise in SLD and ADHD
White noise has been shown to improve working memory and attention in children diagnosed with ADHD . These cognitive abilities are fundamental to the acquisition of reading and writing skills.
- Conditions
- ADHD - Attention Deficit Disorder With Hyperactivity, Specific Learning Disorder, Specific Learning Disability
- Trial name
- WHITE NOISE (NCT07376902)
- Testing
- White noise, No white noise
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS San Raffaele Roma
ADHD
Mindful Awareness Practices for ADHD Pilot Open Trial
It is estimated that 25-40% of youth with ADHD have co-occurring cognitive disengagement syndrome (CDS; previously sluggish cognitive tempo), a set of behavioral symptoms characterized by excessive daydreaming, slowed thinking…
- Trial name
- NCT05584475
- Testing
- Mindful Awareness Practices (MAPs)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
ADHD, Oppositional Defiant Disorder
Adapting a Web-Based Professional Development for Mexican School Mental Health Providers Delivering Evidence-Based Intervention for ADHD and ODD
Neurodevelopmental disorders of inattention and disruptive behavior, such as Attention-Deficit/ Hyperactivity Disorder (ADHD) and Oppositional Defiant Disorder (ODD), are among the most common youth mental health conditions…
- Trial name
- NCT05425966
- Testing
- CLS-R-FUERTE
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of California, San Francisco
Depressive Disorder, AD
Development and Application of Intelligent Diagnosis and Treatment Norms for Children and Adolescents With Mental Disorders
The prevalence of mental disorders and developmental behavioral disorders (such as depressive disorders,anxiety disorders, autism spectrum disorders,attention deficit disorder,ect.)among children and adolescents in China is…
- Conditions
- Depressive Disorder, AD, ASD, ADHD
- Trial name
- NCT06155201
- Testing
- functional training, Observation
- Where
- China
- Volunteers
- 12,000 people
- Sponsor
- Chen Li
Attention Deficit Hyperactivity Disorder, ADHD
Female Experiences and Brain Activity
The Female Experiences and Brain Activity study will investigate how different groups of people process information in different ways.
- Conditions
- Attention Deficit Hyperactivity Disorder, ADHD, Bipolar Disorder
- Trial name
- FEBA (NCT01395160)
- Where
- 2 sites in United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King's College London
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