Clinical trials: Ligament; Laxity
Anterior Cruciate Ligament Injuries
Does ACL Augmented With LEAT Better Controls Rotational Laxity Than Isolated ACL Reconstruction?
It has been suggested that adding a Lateral Extra-Articular Tenodesis (LEAT) to Anterior Cruciate Ligament (ACL) reconstruction has the advantage of better controlling the rotational laxity.
- Trial name
- NCT04136990
- Testing
- Isolated ACL reconstruction, ACL + LEAT reconstruction
- Where
- Portugal
- Volunteers
- 40 people
- Sponsor
- Espregueira-Mendes Sports Centre - FIFA Medical Centre of Excellence
Laxity of Ligament, Pregnancy
Prenatal Pilates and Postpartum Ligamentous Laxity
Pregnancy induces hormonal and biomechanical adaptations that increase ligamentous laxity, which may persist into the postpartum period and contribute to joint instability, pain, and functional limitations.
- Conditions
- Laxity of Ligament, Pregnancy, Pilates Exercise
- Trial name
- NCT07344857
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Ankara Medipol University
Ligament; Laxity, Knee, Anterior Cruciate Ligament Injury
Treatment of Anterior Ligament Rupture With Internal Brace Repair - A Prospective Randomised Controlled Study.
The purpose of this study is to determine whether anterior cruciate ligament injury in patients wishing to return to sports activities may be treated with repair supplemented with internal brace compared with a standard operation…
- Trial name
- NCT03800225
- Testing
- Repair
- Where
- Denmark
- Volunteers
- 4 people
- Sponsor
- Aarhus University Hospital
Vulvodynia, Referred Pain
Is Localized Provoked Vulvodynia Caused by Laxity of the Utero-Sacral Ligaments?
Small-scale experiments conducted by our group have led to the hypothesis that Localized Provoked Vulvodynia (LPV) may be due to laxity of the Utero-Sacral ligaments (USL).
- Trial name
- NCT03197337
- Testing
- Pressure-test
- Where
- Israel
- Volunteers
- 17 people
- Sponsor
- Western Galilee Hospital-Nahariya
Sciatica, Spinal Stenosis of Lumbar Region
Prolotherapy Versus Epidural Steroid Injections (ESI) for Lumbar Pain Radiating to the Leg
The hypothesis is that in the treatment of low back pain (LBP) radiating to the leg, the long-term results of prolotherapy are more effective than those of the current conventional treatment: epidural steroid injections (ESI).
- Conditions
- Sciatica, Spinal Stenosis of Lumbar Region, Degeneration of Lumbar or Lumbosacral Intervertebral Disc
- Trial name
- NCT01934868
- Testing
- prolotherapy solution of 20% dextrose, Epidural Steroid Injection
- Where
- Israel
- Volunteers
- 110 people
- Sponsor
- Hadassah Medical Organization
Knee Ligament Injury
Reference Values for Knee Rotational Amplitudes in a Population of Athletes
Rupture of the anterior cruciate ligament (ACL) is a frequent and disabling injury in pivot sports, leading to knee laxity and instability, reduced performance and an increased risk of early osteoarthritis.
- Trial name
- PRELAX (NCT07013019)
- Testing
- Measures of overall (internal+external) knee rotational amplitudes
- Where
- 2 sites in France
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Genu Varum, Genu Valgus
IMU-based Assessment of Motor Control in a Population of Young Subjects With Paramorphisms and Dysmorphisms
While various complex pathologies of the developmental age, such as Infantile Cerebral Palsy or Neuromuscular Diseases, are notoriously considered causes of alteration of locomotor development, it is scarcely known whether…
- Conditions
- Genu Varum, Genu Valgus, Flat Feet, Cavus Foot
- Trial name
- MOTOR-CHILD (NCT05763901)
- Testing
- Clinical tests and motor control evaluation using Inertial Measurement Units
- Where
- Italy
- Volunteers
- 151 people
- Sponsor
- Istituto Ortopedico Rizzoli
Anterior Cruciate Ligament Injuries, Laxity of Ligament
Agreement Between Rolimeter and Lachmeter in Patients With ACL Injury
The study is a quality assurance study, aiming to determine the agreement between two different measurement instruments for assessing knee joint laxity in patients with ACL injuries.
- Trial name
- NCT05614297
- Testing
- Knee joint laxity test
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Region MidtJylland Denmark
Anterior Cruciate Ligament Tear
Dynamic Knee Laxity Measurement Coupled to MRI in Cases of Suspected Partial Anterior Cruciate Ligament Tear
Anterior cruciate ligament (ACL) tear is frequent, but the diagnosis of partial tears is difficult. Standard MRI may be used but is of limited diagnostic value.
- Trial name
- LaxIRM (NCT02787096)
- Testing
- LaxIRM
- Where
- France
- Volunteers
- 151 people
- Sponsor
- Hospices Civils de Lyon
Knee Ligament; Laxity
Accuracy and Stability of a New Automatic Knee Arthrometer in Diagnosing ACL Rupture
We introduced an automatic knee arthrometer (AKA) and aimed to evaluate the repeatability and effectiveness thereof in diagnosing ACL rupture compared with the KT-2000.
- Trial name
- NCT04956315
- Testing
- Side-to-side difference (reproducibility), Side-to-side difference (availability), Side-to-side difference (Accuracy)
- Where
- China
- Volunteers
- 421 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Primary Knee Arthroplasty
ATTUNE® Revision- Complex Primary in Total Knee Arthroplasty Population
Five-year, Prospective, multi-center, non-randomized, non-controlled study of the ATTUNE® Revision total knee prostheses, utilizing the fixed bearing (FB) and rotating platform (RP) tibial component with the posterior stabilizing…
- Trial name
- NCT03153449
- Testing
- ATTUNE Revision Knee System in Total Knee Arthroplasty
- Where
- 34 sites in United States, Australia and 8 more
- Volunteers
- 400 people
- Sponsor
- DePuy Orthopaedics
Shoulder Dislocation
Electrothermal Arthroscopic Capsulorrhaphy (ETAC) and Open Inferior Capsular Shift in Patients With Shoulder Instability
This trial will compare the effectiveness of electrothermal arthroscopic capsulorrhaphy (ETAC) to the current reference standard procedure, open inferior capsular shift (ICS), for the treatment of shoulder instability caused by…
- Trial name
- NCT00251160
- Testing
- Electrothermal arthroscopic capsulorrhaphy (ETAC), Open inferior capsular shift (ICS)
- Where
- 7 sites in Canada
- Volunteers
- 58 people
- Sponsor
- University of Calgary
Pregnancy, Pilates Exercise
Effects of Pilates Exercises on Laxity in Pregnant Women
The goal of this clinical trial is to investigate whether Pilates exercises can help manage musculoskeletal laxity in pregnant women. It will also examine the safety of Pilates exercises during pregnancy.
- Conditions
- Pregnancy, Pilates Exercise, Laxity of Ligament
- Trial name
- NCT06684002
- Testing
- Pilates training, Standard prenatal care and ergonomic advice
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Selcan Suicmez
Ligament Injury, Ligament; Laxity
Methylsulfonylmethane on Knee Laxity
The proposed research will focus on determining the effect of methylsulfonylmethane (MSM) on knee laxity changes through the menstrual cycle in young active females.
- Conditions
- Ligament Injury, Ligament; Laxity, Tendon Rupture, Tendon Injuries
- Trial name
- NCT03747198
- Testing
- methylsulfonylmethane
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Anterior Cruciate Ligament Rupture
Anterior Cruciate Ligament Rupture
The assess results of Anterior Cruciate Ligament (ACL) repair with the Ligamys® surgical technique versus standard technique. The aim of the study is to compare (laxity, instability, and safety) these two types of treatment by…
- Trial name
- LIGAMYS (NCT02740452)
- Testing
- ligamys technique, standard technique (anatomic reconstruction)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Hypermobility Syndrome, Danlos Disease, Ehlers
Functional Instability in Patients Suffering From Collagen Disease and Joint Hypermobility
A joint is considered "hypermobile" when it has a greater range of motion than normal for a given age, ethnicity or gender. Many people have asymptomatic hyperlaxity in multiple joints, a condition called Generalized Joint…
- Conditions
- Hypermobility Syndrome, Danlos Disease, Ehlers, Collagen Diseases, Joint Hypermobility
- Trial name
- VIPIA (NCT05871216)
- Testing
- Clinical tests and balance evaluation using the Delos Proprioceptive System
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto Ortopedico Rizzoli
Anterior Cruciate Ligament (ACL) Tear
Measuring Knee Laxity and Pivot Shift in ACL-Deficient Patients
The goal of this observational study is to learn whether the Robotic Knee Testing system can measure knee looseness in adults with an anterior cruciate ligament, or ACL, tear.
- Trial name
- NCT07688967
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Arthroresearch LLC
Intraoperative Musculoskeletal Injury
Intraoperative Laxity Assessment of ACL Reconstruction, ACL Revision and MAT
Intraoperative knee laxity evaluation of patiente undergoing ACL reconstruction, ACL revision, MAT
- Trial name
- INTRA_KIN (NCT03441165)
- Testing
- ligament reconstruction and meniscus transplantation
- Where
- Italy
- Volunteers
- 1,500 people
- Sponsor
- Istituto Ortopedico Rizzoli
Ligament; Laxity, Knee, Knee Osteoarthritis
Ligament Balancing in Total Knee Arthroplasty
The goal of this interventional pilot study is to evaluate if performing ligament balancing on the medial collateral ligament (MCL) in a more systematical manner with a novel instrument can produce more objective and repeatable…
- Trial name
- BLIS-TKA (NCT06264076)
- Testing
- A novel instrument for ligament balancing in total knee arthroplasty, Novel Instrument for ligament balancing in knee arthroplasty
- Where
- 2 sites in Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Hormone Influence on Ligament Laxity and Motor Control
Hormone Induced Effects on Ligament Laxity and Lower Extremity Motor Control
The purpose of this study is to expand on previous knowledge of the hormonal effects, specifically estrogen, on ligament laxity, motor control and timing of muscle activation in females.
- Trial name
- NCT04055129
- Testing
- No interventions
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of St. Augustine for Health Sciences