Clinical trials: Ligament Rupture
ACL - Anterior Cruciate Ligament Rupture
Microbiological Molecular Profile of the Knee Joint During Primary Reconstruction or Revision Surgery of the ACL
Anterior cruciate ligament (ACL) reconstructions are common surgical procedures, but a significant number fail for reasons that are not fully understood.
- Trial name
- INFECTIOGEN (NCT07009392)
- Testing
- NGS Analysis
- Where
- France
- Volunteers
- 100 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Ankle (Ligaments); Instability (Old Injury), Ankle Ligament Rupture
French Ankle Ligament Surgery Cohort Study
This 20-year cohort study foolows patients after ankle ligament reconstruction surgery to evaluate re-rupture rates, long term functional outcomes, return to sport rates ans complications? The goal is to provide insights into the…
- Conditions
- Ankle (Ligaments); Instability (Old Injury), Ankle Ligament Rupture, Ankle Instability, Syndesmotic Injury
- Trial name
- AnkleCDS (NCT07188363)
- Testing
- Ligament reconstruction
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- Chirurgie Du Sport
Entrapment Neuropathy, Rotator Cuff Tear
Suprascapular Neuropathy in the Setting of Rotator Cuff Tears: Results of Arthroscopic Treatment
Aim of this prospective double blind randomized clinical trial is to understand the correlation of suprascapular neuropathy in the setting of large and massive tears of the shoulder rotator cuff and to investigate whether…
- Trial name
- SupraCufTear (NCT02318381)
- Testing
- Dissection of the superior transverse scapular ligament
- Where
- Greece
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Hand Injuries, Wrist Injuries
Hand Ligament Reconstructions With Knee Collateral Ligament Allografts
The purpose of this study is to review the clinical outcomes following hand ligament reconstruction surgery using allograft (cadaveric) knee collateral ligaments.
- Conditions
- Hand Injuries, Wrist Injuries, Ligament Injury, Ligament Rupture
- Trial name
- NCT05060900
- Testing
- Ligament Reconstruction with Allograft Ligament
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Cedars-Sinai Medical Center
Rupture of Anterior Cruciate Ligament, Infiltration
Local Infiltration Analgesia vs Adductor Canal Block for Analgesia After Anterior Cruciate Ligament Reconstruction
Early rehabilitation after anterior cruciate ligament reconstruction is of paramount importance and requires optimal pain control based on a multimodal concept, including injection of local anaesthetics.
- Conditions
- Rupture of Anterior Cruciate Ligament, Infiltration, Regional Anesthesia Morbidity
- Trial name
- NCT02524652
- Testing
- Ropivacaine 0.5% 20 mLs
- Where
- Switzerland
- Volunteers
- 104 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Muscle Weakness, Anterior Cruciate Ligament Rupture
Does Gabapentin Reduce Quadriceps Muscle Weakness After Anterior Cruciate Ligament Reconstruction?
Anterior cruciate ligament (ACL) injury is a common sport injury in both professional and recreational athletes. Furthermore, persistent quadriceps weakness and wasting are frequently observed after anterior cruciate ligament…
- Trial name
- NCT03496389
- Testing
- Gabapentin, Tramadol, Panadol
- Volunteers
- 30 people
- Sponsor
- Hospital Authority, Hong Kong
Anterior Cruciate Ligament Rupture
The Effect of Subtalar Joint Antipronation Taping on the Dynamic Knee Valgus in Female Volleyball Players with Low Medial Arch
This study aims to investigate the biomechanical mechanisms of dynamic knee valgus and the impact of subtalar pronation, particularly due to decreased medial longitudinal arch, on knee injury risk, highlighting the importance of…
- Trial name
- NCT06752109
- Testing
- Antipronation Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Ankara Yildirim Beyazıt University
Uterovaginal Prolapse, Prolapse of Vaginal Vault After Hysterectomy
Compare Sacrospinous Fixation Versus High Uterosacral Ligament Fixation for Uterus Vaginal Prolapse III/IV
The purpose of this study is to compare the vaginal sacrospinous colpopexy and high uterosacral colpopexy in the treatment of genital prolapse grade III/IV in women with uterus.
- Conditions
- Uterovaginal Prolapse, Prolapse of Vaginal Vault After Hysterectomy, Complete Tear, Sacrospinous Ligament, Uterosacral Ligament; Rupture
- Trial name
- NCT01347021
- Testing
- sacrospinous colpopexy versus high uterosacral colpopexy
- Where
- Brazil
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Anterior Cruciate Ligament Tear
Comparison of Early Versus Delay Reconstruction in Anterior Cruciate Ligament Tearing
The purpose of this study is to determine which surgical method is better for anterior cruciate ligament teas in outcomes.
- Trial name
- NCT01580722
- Testing
- early reconstruction, delay reconstruction
- Where
- Iran
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Blood Flow Restriction, ACL Tear
Blood Flow Restriction Training (BFR) in an Adolescent Population
While there are a number studies that have reported on the use of BFR in the adult population, there is limited information about the use of BFR in the adolescent population.
- Conditions
- Blood Flow Restriction, ACL Tear, ACL Injury
- Trial name
- NCT04285879
- Testing
- Blood Flow Restriction using Delfi Personalized Tourniquet System
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Connecticut Children's Medical Center
ACL Injury, ACL Augmentation
Augmentation of Partial Anterior Cruciate Ligament Tear: Early Results
Clinical evaluation for the patients with partial ACL tear who had ACL augmentation
- Trial name
- Augmentation (NCT05391672)
- Testing
- we will do ACL augmentation surgery to the patients who have partial ACL tear
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Rupture of Anterior Cruciate Ligament, Muscle Degeneration
Can Targeted Exercise Improve Knee Strength Following ACLR (RATE)
Anterior cruciate ligament reconstruction (ACLR) is high volume surgery, carried out in about 2800 patients annually in Denmark per year.
- Conditions
- Rupture of Anterior Cruciate Ligament, Muscle Degeneration, Gait, Unsteady
- Trial name
- RATE (NCT02939677)
- Testing
- Targeted exercise
- Where
- Denmark
- Volunteers
- 51 people
- Sponsor
- University of Southern Denmark
ACL Rupture, Replacement
Long Term Follow-up of the "Stryker Dacron and Trevira Ligament" for Anterior Cruciate Ligament (ACL) Repair
About 20 years ago synthetic ligaments were used in orthopaedics / traumatology for the repairing and replacement of injuries of the anterior cruciate ligament.
- Trial name
- NCT01138696
- Testing
- Questionnaires, RX
- Where
- 2 sites in Belgium
- Volunteers
- 80 people
- Sponsor
- University Hospital, Ghent
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Reliability and Validity of Inline Dynamometry Study for Measuring Knee Extensor Torque
This study will investigate the reliability and validity of an inline 'pull-type' dynamometer for measuring peak knee extensor torque.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- NCT05109871
- Testing
- KForce Link
- Where
- United Kingdom
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Ligament; Laxity, Knee, Rupture of Anterior Cruciate Ligament
Anterior Cruciate Ligament-reconstruction: Quadriceps Tendon or Hamstrings Tendon? A Prospective Trial
The purpose of this study is to determine whether there is a difference in muscle strength after anterior cruciate ligament comparing 2 surgery technics. Using either autograft hamstrings tendon or a autograft quadriceps tendon.
- Trial name
- NCT02173483
- Testing
- Quadriceps graft
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Aarhus University Hospital
ACL Injury, ACL Sprain
Isoinertial Rehabilitation in Recovering Hamstring Strength Following Surgical Anterior Cruciate Ligament Reconstruction
The present experimental study aims to evaluate the effectiveness and tolerability of isoinertial strength training of the hamstrings using machines in patients with ACL-R during the intermediate post-intervention phases.
- Conditions
- ACL Injury, ACL Sprain, ACL Tear, Anterior Cruciate Ligament Rupture
- Trial name
- NCT06063915
- Testing
- Isoinertial training, Strength Training
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Università degli studi di Roma Foro Italico
Anterior Cruciate Ligament Rupture, Surgery
ALL Ultrasound Predicts the Success of ACL Repair?
This case series evaluates whether patients with an anterior cruciate ligament (ACL) repair have better outcome if the anterolateral ligament (ALL) was repaired or not considering the ultrasound (US) pre-surgical recommendation.
- Trial name
- ALL_US (NCT04373408)
- Testing
- ACL repair without anterolateral repair, ACL repair with anterolateral repair
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Adrien Schwitzguebel
Complete Tear, Knee, Anterior Cruciate Ligament
Early Viscosupplementation After ACL Reconstruction: a Randomized Controlled Trial
The possibility of using an intra-articular agent such as hyaluronic acid (HA) to reduce the post-operative inflammatory stress on the knee joint, limiting the use of other pain-killers and promoting a faster recovery after ACL…
- Trial name
- HA-ACL (NCT02630407)
- Testing
- viscosupplementation
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Istituto Ortopedico Rizzoli
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Tendon-Bone Versus All-Soft-Tissue for ACL Reconstruction: A Patient-Blinded Randomized Clinical Trial
In primary pediatric Anterior cruciate ligament (ACL) reconstruction, the quadriceps tendon with either tendon and patellar bone or an all-tendon graft is commonly employed.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- NCT04039971
- Testing
- ACL Reconstruction
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Colorado, Denver
ACL Tear
Augmentation of Anterior Cruciate Ligament Reconstruction Using Mesenchymal Stem Cells and Collagen Matrix Carrier
The goal of this observational study is to compare patient outcomes for reconstructive surgery of ACL tears. This study utilizes two randomized groups, one being the control group that receives standard ACL reconstructive…
- Trial name
- BioACL (NCT05582226)
- Testing
- ACL reconstruction, Mesenchymal stem cell implantation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Andrews Research & Education Foundation