Clinical trials: Ligament Rupture
Adypose Mesenchimal Stem Cell, Ligament Rupture
Regeneration of Posterior Cruciate Ligament Injury Using Hypoxic Conditioned Allogenic Adipose Mesenchymal Stem Cell and Condition Medium
Transplantation of Allogenic Adipose Mesenchimal Stem cell in hypoxic cultur condition with Ligament- derived conitioned medium can enhance regeneration of posterior cruciate ligament rupture
- Conditions
- Adypose Mesenchimal Stem Cell, Ligament Rupture, Ligament Derived Conditined Medium
- Trial name
- NCT04889963
- Testing
- adypose mesenchymal conditioned medium and ligament derived conditioned medium
- Where
- Indonesia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Gadjah Mada University
Posterior Cruciate Ligament Tear
Assessment of Outcomes of Double-bundle Posterior Cruciate Ligament Reconstruction (DB-PCLR)
Double-bundle Posterior Cruciate Ligament Reconstruction (DB-PCLR) is becoming increasingly used alternative to the single-bungle PCLR. While more technically challenging, it seems to better improve patients' outcomes.
- Trial name
- NCT05701592
- Testing
- DB-PCLR
- Where
- Poland
- Volunteers
- 10 people
- Sponsor
- Konrad Malinowski MD
Anterior Cruciate Ligament Tear
Dynamic Knee Laxity Measurement Coupled to MRI in Cases of Suspected Partial Anterior Cruciate Ligament Tear
Anterior cruciate ligament (ACL) tear is frequent, but the diagnosis of partial tears is difficult. Standard MRI may be used but is of limited diagnostic value.
- Trial name
- LaxIRM (NCT02787096)
- Testing
- LaxIRM
- Where
- France
- Volunteers
- 151 people
- Sponsor
- Hospices Civils de Lyon
Rupture of Anterior Cruciate Ligament
Anterior Cruciate Ligament (ACL) Reconstruction- Bioabsorbable Screw
To evaluate the knee functionality, screw integrity, graft integrity, cartilage effect, and bony ingrowth in patients treated with the CALAXO screw and MILAGRO screw two years after ACL reconstruction.
- Trial name
- NCT01069588
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Vanderbilt University Medical Center
Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
Quantifying the Benefits of Supervised vs. Unsupervised Pre-habilitation for Patients With Acute ACL Tears
Although the success of physical therapy following surgery has been well-documented and validated in patients undergoing Anterior Cruciate Ligament Reconstruction (ACLR) procedures, more recent studies have demonstrated that…
- Conditions
- Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Injuries
- Trial name
- NCT04593264
- Testing
- Self-guided pre-habilitation exercise program, Traditional pre-habilitation
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- WellSpan Health
Anterior Cruciate Ligament Tear, Ankle Sprains
Effect of ACL Reconstruction in Biomechanical Properties of Ankle Joint Complex
BACKGROUND: Anterior cruciate ligament (ACL) is an important ligamentous structure in the knee joint which contributes in maintaining stability.
- Trial name
- NCT06631690
- Testing
- Isokinetic and functional balance tests
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
ACL - Anterior Cruciate Ligament Rupture, ACL Injury
Longitudinal Assessment of Cartilage Injury and Remodeling After Anterior Cruciate Ligament Rupture and Reconstruction:
The proposed study will establish novel relationships between intra-articular mesenchymal stem cell (MSC) recruitment, synovial inflammation, biomarkers of cartilage degeneration and joint inflammation, clinical patient factors…
- Conditions
- ACL - Anterior Cruciate Ligament Rupture, ACL Injury, Healthy
- Trial name
- NCT03497780
- Testing
- Anterior cruciate ligament reconstruction
- Where
- 2 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Ankle Fractures, Ligament Rupture
A New Method for Deltoid Ruptures: Gap Sign
"Deltoid Gap Sign" which would be a new method of examination for deltoid ligament injuries will be investigated. It will be analyzed if it is correlated with the external rotation stress test.
- Conditions
- Ankle Fractures, Ligament Rupture, Ligament Injury
- Trial name
- NCT05188391
- Testing
- Deltoid Gap Sign
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Goztepe Training and Research Hospital
ACL Tear
Anterior Cruciate Ligament (ACL) Reconstruction With Bone Tendon Bone Autograft With Versus Without Internal Bracing
There is no consensus regarding the best surgical management of primary ACL tears. Recent evidence suggests that internal brace augmentation may increase load failure and therefore stabilize the graft in-situ at the time of ACL…
- Trial name
- NCT05532189
- Testing
- ACL reconstruction with BTB autograft with internal brace augmentation (suture tape), ACL reconstruction with BTB autograft without internal brace augmentation (suture tape), Standardized Rehabilitation Protocol
- Volunteers
- healthy volunteers welcome
- Sponsor
- Columbia University
Anterior Cruciate Ligament Rupture
Single Bundle Anterior Cruciate Ligament Reconstruction in Active Young Men
The clinical outcomes of anterior cruciate ligament reconstruction using free tendon Achilles allograft are comparable to those using Achilles allograft with bone block on its end.
- Trial name
- NCT01533025
- Testing
- anterior cruciate ligament reconstruction
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- National Police Hospital
Knee Injury, ACL Injury
Reducing Disparities in Knee Arthroscopy for Adolescents
Hundreds of thousands of youth athletes require surgery for knee injuries annually. The incidence of operative knee injuries has skyrocketed, but surgery can be delayed due to late recognition and barriers, such as insurance…
- Conditions
- Knee Injury, ACL Injury, Meniscus Tear, Hispanic or Latino
- Trial name
- RED KARD (NCT07580625)
- Testing
- Educational program and patient navigator
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
ACL Tear, Opioid Misuse
Exparel vs. ACB With Bupivacaine for ACL Reconstruction
Opioid misuse and addiction among children and adolescents is an increasingly concerning problem. Post-surgical opioid prescriptions for commonly performed surgeries such as anterior cruciate ligament reconstruction (ACLR)…
- Conditions
- ACL Tear, Opioid Misuse, Pain, Anxiety
- Trial name
- NCT06274008
- Testing
- Exparel
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Orange County
Wrist Internal Derangement, Triangular Fibrocartilage Complex Tears
Added Diagnostic Value of CT Arthrography to MR Arthrography in Wrist Internal Derangement
The wrist is a complex joint made up of small bones, cartilage, and stabilizing ligaments, including the triangular fibrocartilage complex (TFCC) and intrinsic carpal ligaments.
- Conditions
- Wrist Internal Derangement, Triangular Fibrocartilage Complex Tears, Scapholunate Ligament Tears, Lunotriquetral Ligament Tears
- Trial name
- NCT07826208
- Testing
- Combined CT Arthrography and MR Arthrography
- Volunteers
- 60 people
- Sponsor
- Assiut University
Anterior Cruciate Ligament Tear
IPACK Versus Popliteal Sciatic Nerve Block in ACL Reconstruction
This is a prospective study comparing femoral nerve block plus sciatic nerve block to femoral nerve block plus infiltration of the posterior knee capsule (IPACK) in patients undergoing arthroscopic anterior cruciate ligament…
- Trial name
- NCT03983941
- Testing
- Ropivacaine injection
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Sujana Dontukurthy
Scapholunate Ligament Rupture
Scapholunate Ligament Reconstruction: Early Dart Throwing Motion Versus Motion in Anatomical Planes
Patients undergoing scapholunate ligament reconstruction at Balgrist University Hospital are divided into two groups and receive two different types of mobilisation postoperatively.
- Trial name
- SL-Reko (NCT06590701)
- Testing
- Early dart throwing motion-mobilization
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lisa Reissner
Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction Rehabilitation
Anterior Cruciate Ligaments: Studying Updates in neuroCognition After Knee Manipulation
This study will investigate whether knee joint manipulation can improve neurocognitive and neuromuscular performance in individuals with a history of anterior cruciate ligament reconstruction (ACLR).
- Trial name
- ACLs SUCK (NCT07058467)
- Testing
- Joint Manipulation
- Where
- United States
- Sponsor
- University of North Carolina, Chapel Hill
Rupture of Anterior Cruciate Ligament
Quadriceps Function Prior to Anterior Cruciate Ligament Reconstruction
Patients who are diagnosed with an isolated tear of the anterior cruciate ligament and scheduled for arthroscopic reconstruction using bone-patellar tendon-bone autograft will be recruited to participate.
- Trial name
- NCT00971451
- Testing
- cryotherapy, TENS
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Virginia
ACL Tear
ACL Bone Health and Loading Study
The purpose of this study is to look at the effects of bone density on lower extremity loading mechanics using Blood Flow Restriction (BFR) to provide the control group for bone health.
- Trial name
- ACLBONE (NCT04682392)
- Testing
- Delfi's PTS Personalized Tourniquet System for Blood Flow Restriction Group, Standard ACL rehab
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Candice Dunkin, MS, LAT, ATC
Anterior Cruciate Ligament Rupture
Central Sensitization Symptoms and Psychosocial Factors in Athletes After ACL Reconstruction
The main research objective of this study is whether athletes who have sustained an anterior cruciate ligament injury, experience chronic nociplastic pain and psychosocial factors, including kinesiophobia and pain…
- Trial name
- NCT04393129
- Where
- Greece
- Volunteers
- 39 people
- Sponsor
- University of Thessaly
Complete Tear, Knee, Anterior Cruciate Ligament
Gait Rehabilitation Following an Anterior Cruciate Ligament Reconstruction
A randomized control trial where subjects following an anterior cruciate ligament reconstruction will be randomized to either a control group who will receive the normal rehabilitation or an experimental group who will perform a…
- Trial name
- NCT02930239
- Testing
- Gait rehabilitating with reduced bodyweight, Standardized rehabilitation following an anterior cruciate ligament reconstruction at Linkoping University Hospital
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Linkoeping University