Clinical trials: Ligament Rupture
ACL Injury, ACL Tear
The Pediatric ALL Evaluation and Trial
The overall aim of this multicenter RCT is to determine whether concomitant ALL reconstruction in children undergoing and ACL reconstruction will longitudinally result in a lower rate of graft failure than ACL reconstruction…
- Trial name
- PALLET (NCT04825587)
- Testing
- Patients will be randomized into one of two study arms: (1) concomitant ACL and ALL reconstruction or (2) ACL reconstruction alone.
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Anterior Cruciate Ligament Rupture
Induced ACL Healing With the Ligamys Technique: a Prospective, Multicenter Observational Case Series
The purpose of this study is to evaluate the safety and effectiveness of the Ligamys technique for the treatment of acute ruptures of the anterior cruciate ligament in a multicenter routine clinical setting.
- Trial name
- Ligamys (NCT02203214)
- Testing
- Ligamys
- Where
- 3 sites in Belgium, Germany and 1 more
- Volunteers
- 110 people
- Sponsor
- Mathys Ltd Bettlach
Anterior Cruciate Ligament Rupture, Deficiency of Anterior Cruciate Ligament
Comparison of Three Methods for Anterior Cruciate Ligament Reconstruction
The purpose of this randomized clinical trial is to determine the difference in quality of life outcome at two years, in patients undergoing an Anterior Cruciate Ligament (ACL) reconstruction procedure with either a patellar…
- Conditions
- Anterior Cruciate Ligament Rupture, Deficiency of Anterior Cruciate Ligament, Chronic Instability of Knee, Anterior Cruciate Ligament Injury
- Trial name
- NCT00529958
- Testing
- Patellar Tendon, Hamstring Tendon, Double-Bundle
- Where
- Canada
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Radial Head Fractures
Radiological and Clinical Outcome After Screw Osteosynthesis of Radial Head Fractures
This cohort study investigates radiological and clinical outcome after screw osteosynthesis of radial head fractures with associated injuries (such as rupture of the interosseous membrane and collateral ligaments).
- Trial name
- RadioHead (NCT03944590)
- Testing
- patient survey, analysis of radiographs
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University Hospital, Basel, Switzerland
Athletic Injuries (C26.857.500.124), Rotator Cuff Injuries
Clinical Outcomes of Arthroscopic Surgeries for Shoulder and Knee Sports Injuries
This observational study aims to evaluate the long-term recovery and clinical outcomes of patients undergoing minimally invasive (arthroscopic) surgeries for sports-related shoulder and knee injuries.
- Conditions
- Athletic Injuries (C26.857.500.124), Rotator Cuff Injuries, Tibial Meniscus Injuries, Shoulder Dislocation or Subluxation
- Trial name
- SK-COHORT (NCT07501013)
- Testing
- Standard of Care Shoulder Arthroscopy, Standard of Care Knee Arthroscopy
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Achilles Allograft With or Without InternalBrace for ACL Revision Surgery
This study evaluated outcomes after revision anterior cruciate ligament reconstruction using Achilles tendon allografts with a calcaneal bone block, with or without additional InternalBrace augmentation.
- Conditions
- Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Graft Failure, Knee Instability
- Trial name
- ACL-AlloRev (NCT07564336)
- Testing
- Revision ACL Reconstruction With Achilles Tendon Allograft and InternalBrace Augmentation, Revision ACL Reconstruction With Achilles Tendon Allograft Without InternalBrace Augmentation
- Where
- Austria
- Volunteers
- 32 people
- Sponsor
- Medical University of Graz
Acute Ruptures of the Anterior Cruciate Ligament
L-C Ligament Versus Hamstring Autograft for Primary ACL Reconstruction
The purpose of this study is to compare safety and efficacy outcomes of the L-C Ligament versus Hamstring Autograft for treatment of acute rupture of the ACL.
- Trial name
- NCT02183727
- Testing
- L-C Ligament, Hamstring Autograft
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Soft Tissue Regeneration, Inc.
Complete Tear, Knee, Anterior Cruciate Ligament, Rupture of Anterior Cruciate Ligament
Tibial Tunnel Placement for ACL Reconstruction
Although extensive research has been carried out on Anterior Cruciate Ligament (ACL) femoral tunnel placement, very little attention has been given to the tibial tunnel.
- Trial name
- NCT02374710
- Testing
- ACL Reconstruction: Anterior Tunnel, ACL Reconstruction: Posterior Tunnel
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Virginia
ACL Injury, MRI
Evaluation of Anterior Cruciate Ligament Tears Using Diffusion Tractography
Knees injuries commonly affect the ACL. French current methodology is based on MRI focused on the knee with morphological sequences (T1, DP fat sat) allowing the study of ACL as follows: No lesion / Partial tear / Complete tear.
- Conditions
- ACL Injury, MRI, Tractography
- Trial name
- TRACTOLCA (NCT05806034)
- Testing
- tractography MRI sequence protocol
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Knee Injuries, ACL Tear
ACL Reconstruction With Simple and Double Bundle Technique Using Two Different Implants for Graft Fixation
In this study our objective is to compare two tibial ACL graft fixation systems in patients undergoing two different reconstructions technique (with simple and double bundle) in terms of tendon graft osteointegration…
- Conditions
- Knee Injuries, ACL Tear, ACL Injury, Sports Injury
- Trial name
- NCT04550299
- Testing
- Surgical technique combined with a specific choice of the material for the ligament reconstruction
- Where
- Brazil
- Volunteers
- 112 people
- Sponsor
- Vita Care
Anterior Cruciate Ligament Rupture
Pain Relief Results After Anterior Cruciate Ligament (ACL) Reconstruction
Anterior cruciate ligament (ACL) reconstruction is surgery that is done to repair a damaged ligament in the knee. In this study we will look at whether the femoral nerve block, a commonly used method for pain relief after ACL…
- Trial name
- NCT00022854
- Testing
- Single-injection femoral nerve block, Femoral nerve block 60-hour continuous injection, Saline (control) injection into femoral nerve envelope
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- University of Pittsburgh
ACL, ACL Injury
Reduced Knee Flexion Strength 18 Years After ACL Reconstruction in Hamstring Group Compared to Patellar Tendon Group
Background: Bone-patellar tendon-bone (BPTB) and a double-looped semitendinosus gracilis (hamstring group) graft are commonly used for ACL reconstruction.
- Conditions
- ACL, ACL Injury, Cruciate Ligament Rupture, ACL Tear
- Trial name
- Studie ACL (NCT05876013)
- Testing
- ACL reconstruction
- Where
- Norway
- Volunteers
- 114 people
- Sponsor
- St. Olavs Hospital
Entrapment Neuropathy, Rotator Cuff Tear
Suprascapular Neuropathy in the Setting of Rotator Cuff Tears: Results of Arthroscopic Treatment
Aim of this prospective double blind randomized clinical trial is to understand the correlation of suprascapular neuropathy in the setting of large and massive tears of the shoulder rotator cuff and to investigate whether…
- Trial name
- SupraCufTear (NCT02318381)
- Testing
- Dissection of the superior transverse scapular ligament
- Where
- Greece
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Anterior Cruciate Ligament Tear
IL-1RA Treatment in Patients With Acute ACL Tear and Painful Effusions
Injury to the knee during sports participation often involves partial or full detachment of the anterior cruciate ligament (abbreviated as ACL). ACL tears cause pain, swelling and inflammation.
- Trial name
- EASI ACL (NCT02930122)
- Testing
- anakinra (150mg), Saline intraarticularly
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Cale Jacobs, PhD
Muscle Weakness, Anterior Cruciate Ligament Rupture
Does Gabapentin Reduce Quadriceps Muscle Weakness After Anterior Cruciate Ligament Reconstruction?
Anterior cruciate ligament (ACL) injury is a common sport injury in both professional and recreational athletes. Furthermore, persistent quadriceps weakness and wasting are frequently observed after anterior cruciate ligament…
- Trial name
- NCT03496389
- Testing
- Gabapentin, Tramadol, Panadol
- Volunteers
- 30 people
- Sponsor
- Hospital Authority, Hong Kong
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Physical Activity, Knee Joint Loading and Joint Health
The purpose of this study is to investigate the association between time spent in moderate to vigorous physical activity and markers of cartilage metabolism in the years following anterior cruciate ligament reconstruction.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Post-traumatic Osteoarthritis
- Trial name
- NCT05306054
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Bath
Anterior Cruciate Ligament Rupture
The Effect of Subtalar Joint Antipronation Taping on the Dynamic Knee Valgus in Female Volleyball Players with Low Medial Arch
This study aims to investigate the biomechanical mechanisms of dynamic knee valgus and the impact of subtalar pronation, particularly due to decreased medial longitudinal arch, on knee injury risk, highlighting the importance of…
- Trial name
- NCT06752109
- Testing
- Antipronation Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Ankara Yildirim Beyazıt University
Cruciate Ligament Reconstruction, Cruciate Ligament Rupture
Biological Potentials in Arthroscopic All-inside Semitendinosus Anterior Cruciate Ligament Reconstruction
A randomized, double-blind, prospective single-center clinical trial evaluating the effect of biological augmentation in anterior cruciate ligament (ACL) reconstruction.
- Conditions
- Cruciate Ligament Reconstruction, Cruciate Ligament Rupture, Cruciate Ligament Injury
- Trial name
- BioACL (NCT07506304)
- Testing
- ACL reconstruction
- Volunteers
- 70 people
- Sponsor
- University Hospital Dubrava
Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Rupture
Effects of Platelet Rich Plasma Injections on Biomarkers After Anterior Cruciate Ligament Tears
A potential long-term consequence of anterior cruciate ligament injuries is the development of post-traumatic osteoarthritis in the years following injury.
- Trial name
- NCT04088227
- Testing
- Experimental Group, Control Group
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Andrews Research & Education Foundation
Anterior Cruciate Ligament (ACL) Tear
Low Level Laser Therapy Versus Short Wave Diathermy in Patients With Anterior Cruciate Ligament Tear
This clinical research study is comparing two non-surgical treatments-Low-Level Laser Therapy (LLLT) and Short Wave Diathermy (SWD)-to see which is more effective for people with a partial tear of the anterior cruciate ligament…
- Trial name
- NCT07089459
- Testing
- Low-Level Laser Therapy (LLLT), Shortwave therapy
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- University of Lahore