Clinical trials: Ligament Tear Knee
Rupture of Anterior Cruciate Ligament, Osteoarthritis
French Prospective Anterior Cruciate Ligament Reconstruction Cohort Study (FAST)
In this study we will examine patients who have undergone anterior cruciate and/or posterior cruciate ligament and/or multi ligaments reconstruction to determine the rate of re-injury, contralateral tear and functional outcomes…
- Trial name
- FAST (NCT02511158)
- Testing
- Ligament of the knee reconstruction
- Where
- France
- Volunteers
- 7,000 people
- Sponsor
- Fonds de Dotation pour la Recherche Clinique en Orthopédie et Pathologie du Sport
Knee Sprain (Mild), Knee Sprain (Moderate)
Assessment of the Safety and Performance of Knee Ligament Supports in the Context of a Return to Sport After Sprain
Decathlon has developed kneeMID500-STRONG700 products which are two medical devices designed to be used for sport resumption after mild (kneeMID500) or moderate (KneeSTRONG100) knee sprain or after an Anterior Cruciate Ligament…
- Conditions
- Knee Sprain (Mild), Knee Sprain (Moderate), Anterior Cruciate Ligament Tear
- Trial name
- NCT04592471
- Testing
- kneeMID500-STRONG700
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- Decathlon SE
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Clinical and Biological Outcomes of BioBrace-Augmented ACL Reconstruction
This prospective, single-center, single-arm observational cohort study aims to evaluate the clinical, radiological, and arthroscopic outcomes and safety of primary anterior cruciate ligament (ACL) reconstruction augmented with…
- Trial name
- NCT07906860
- Testing
- BioBrace® Reinforced BioInductive Implant
- Volunteers
- 30 people
- Sponsor
- Yonsei University
Anterior Cruciate Ligament Rupture
Improvement of Knowledge About the Arthrogenic Muscle Inhibition in the Aftermath of Knee Trauma.
Arthrogenic Muscle Inhibition (AMI) is one of the classic complications occurring in the aftermath of knee trauma; AMI is grossly defined as a lack of extension due to quadriceps inhibition and hamstring contracture.
- Trial name
- CAMIK (NCT03950024)
- Testing
- functional brain MRI
- Where
- France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Toulouse
Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Injuries
Over-the-Top vs. Anteromedial ACLR With Lateral Extraarticular Tenodesis
This study aims to compare the over-the-top (OTT) anterior cruciate ligament (ACL) reconstruction (ACL-R) technique with the anteromedial ACL-R + lateral extraarticular tenodesis (LET).
- Conditions
- Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Tear
- Trial name
- NCT06664047
- Testing
- OTT ACLR, ACLR LET
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people
- Sponsor
- Ankara City Hospital Bilkent
Anterior Cruciate Ligament Rupture
Evaluation After Reconstruction of the Anterior Cruciate Ligament of the Knee Using the Bioresorbable Interference Screw (SMS): Resorbability, Per- and Post-operative Complications and Articular Functional Recovery.
The investigators will evaluate the benefit of a new bioresorbable screw for repair of anterior cruciate ligament over 3 years.
- Trial name
- BIORELICA (NCT03529552)
- Testing
- Anterior Cruciate Ligament Reconstruction
- Where
- 3 sites in France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
ACL - Anterior Cruciate Ligament Rupture, ACL Injury
Can PRP Reduce Pro-Inflammatory Biomarkers Following ACL Injury
The purpose of this single-center, double-blinded randomized control trial with prospective data collection is to assess the ability of platelet rich plasma (PRP) treatment to reduce the level of pro-inflammatory synovial fluid…
- Trial name
- NCT03389685
- Testing
- Platelet Rich Plasma
- Where
- United States
- Sponsor
- NYU Langone Health
Athletic Injuries (C26.857.500.124), Rotator Cuff Injuries
Clinical Outcomes of Arthroscopic Surgeries for Shoulder and Knee Sports Injuries
This observational study aims to evaluate the long-term recovery and clinical outcomes of patients undergoing minimally invasive (arthroscopic) surgeries for sports-related shoulder and knee injuries.
- Conditions
- Athletic Injuries (C26.857.500.124), Rotator Cuff Injuries, Tibial Meniscus Injuries, Shoulder Dislocation or Subluxation
- Trial name
- SK-COHORT (NCT07501013)
- Testing
- Standard of Care Shoulder Arthroscopy, Standard of Care Knee Arthroscopy
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Proprioceptive Disorders
Evaluation of Proprioceptive Abilities While Wearing an Elastic Orthosis in Patients With Proprioceptive Knee Deficits
The objective of the study is to compare, with or without wearing an elastic proprioceptive knee brace, the functional proprioceptive capacity of the knee in patients suffering from proprioceptive deficit.
- Trial name
- CAPROG (NCT05435040)
- Testing
- proprioceptive knee brace, No knee brace
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Thuasne
ACL Tear
CT Evaluation of ACL Anatomical Reconstruction
Our research is to evaluate the position and length of femoral tunnel, and to examine whether knee stability and clinical functional outcomes are better while using two-portal or three-portal technique .
- Trial name
- NCT06575543
- Testing
- CT
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Assiut University
ACL Tears
MRI Evaluation of Graft Maturation Following ACL Reconstruction
Post-surgical ACL Graft maturation will be assessed at 4.5, 6, 7.5, 9, 10.5, and 12 months with MRI.
- Trial name
- NCT07046000
- Testing
- MRI
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Skye Biologics Holdings, LLC
ACL - Anterior Cruciate Ligament Rupture
Comparison of Arthrogenic Muscle Inhibition (AMI) After ACL Reconstruction in Patients With Conventional Rehabilitation or Conventional Rehabilitation Combined With Digital Therapy
Traumatic injury to the knee joint, such as rupture of the anterior cruciate ligament (ACL), can compromise the voluntary activation capacity of the quadriceps despite the anatomical integrity of the nerve and muscle structures…
- Trial name
- AMITHENUM (NCT07030764)
- Testing
- DOCT'UP, Physiotherapy
- Where
- France
- Volunteers
- 448 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Anterior Cruciate Ligament Injuries, Ligament; Rupture, Knee, Spontaneous
Functional Outcome Comparison of Implant-Free Bone-Patellar Tendon Autograft in Arthroscopic ACL Reconstruction
The use of implants for conventional anterior cruciate ligament (ACL) graft fixation has been associated with several problems including graft injury, implant osteolysis, implant migration and soft tissue irritation.
- Conditions
- Anterior Cruciate Ligament Injuries, Ligament; Rupture, Knee, Spontaneous, Tendon Graft; Complication, Mechanical
- Trial name
- NCT04123834
- Testing
- Patella tendon & bone block autograft + press-fit femoral technique, Arthroscopic ACL reconstruction, Hamstring tendon autograft + implant fixation
- Volunteers
- 32 people
- Sponsor
- Universitas Indonesia
Meniscus Tear, Meniscus Lesion
Clinical and Instrumental Assessment of Meniscal ROOT Tears Treated Through Suture to the Posterior Cruciate Ligament
The menisci are crucial for knee stability and functionality. Composed of fibrocartilaginous structure, they have an anatomical and biomechanical arrangement that makes them essential for load transmission and the prevention of…
- Conditions
- Meniscus Tear, Meniscus Lesion, Knee Injuries
- Trial name
- ROOT-PCL (NCT06507241)
- Where
- Italy
- Volunteers
- 59 people
- Sponsor
- Istituto Ortopedico Rizzoli
Anterior Cruciate Ligament Tear
The Effect of Perioperative and Postoperative Music Reduces Pain Perception After Anterior Cruciate Ligament Reconstruction
study the effect of music therapy in pre-operative and post operative period and measure the out come by the visual analog scale (pain score) and analgesic drug use such as morphine and the anxiety score
- Trial name
- NCT06275828
- Testing
- slow beat mesic listening by headphone
- Where
- Thailand
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Police General Hospital, Thailand
Anterior Cruciate Ligament Tear
Moderated Blood Flow Restriction After Anterior Cruciate Ligament Reconstruction
The aim of this study is to determine if there is a difference in post operative rehabilitation after anterior cruciate ligament (ACL) reconstruction surgery while using moderated blood flow therapy vs. standard physical therapy.
- Trial name
- Delfi (NCT02911909)
- Testing
- Delfi, Standard rehabilitation
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Missouri-Columbia
Anterior Cruciate Ligament Rupture
"Online Surveys" in Perioperative Knee Anterior Cruciate Ligament (ACL) Reconstruction
To monitor the quality of health care systems, patient-reported outcome measures (PROMs) should be collected and analyzed before and after medical interventions.
- Trial name
- ORTHENSE (NCT05423314)
- Testing
- knee brace cold therapy
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Toulouse
Anterior Cruciate Ligament Rupture, Osteoarthritis, Knee
A Cohort Study of Non-surgical Treatment and Exercise Rehabilitation in Patients With Anterior Cruciate Ligament Rupture
This clinical trial compared the prognosis of surgical and non-surgical treatment in patients with complete anterior cruciate ligament rupture
- Trial name
- NCT05403905
- Testing
- non surgical treatment, surgical treatment
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
ACL Injury, ACL - Anterior Cruciate Ligament Rupture
The Rehabilitation Effect of Exercise Training in Cruciate Ligament Reconstruction Patients.
After anterior cruciate ligament (ACL) injury, the involved quadriceps may demonstrate weakness due to decrease in quadriceps activation.
- Conditions
- ACL Injury, ACL - Anterior Cruciate Ligament Rupture, ACL - Anterior Cruciate Ligament Deficiency
- Trial name
- NCT03359382
- Testing
- Resistance or home exercise combined with eccentric exercise
- Where
- Taiwan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Sports Injury
Clinical Study of Platelet-rich Plasma Promoting Tendon-bone Healing in Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) injury is a common knee injury, which seriously affects the living ability and sport level of the injured. ACL reconstruction is the main method to treat ACL injury.
- Trial name
- NCT04659447
- Testing
- Platelet-Rich Plasma
- Volunteers
- 60 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital