Clinical trials: Ligament Tear Knee
Rupture of Anterior Cruciate Ligament
Biomechanical Analysis of Dynamic Tasks and Muscular Strength Following Anterior Cruciate Ligament Reconstruction
Background Anterior cruciate ligament (ACL) injuries are one of the most common sporting injuries of the knee. ACL reconstruction (ACLR) has become one of the most common surgical procedures in an attempt to increase joint…
- Trial name
- NCT02771548
- Testing
- Anterior Cruciate Ligament Reconstruction
- Where
- Ireland
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Dr Neil Welch ASCC
Posterior Cruciate Ligament Tear
The Biomechanical Mechanism for Gait and Plantar Pressure Changes After Posterior Cruciate Ligament Rupture and Reconstruction
Investigating the biomechanics for the PCL ruptured or reconstructed patients during walking, jogging, cutting, jumping. To establish a knee joint biomechanical evaluation model to quantify and evaluate the plantar pressure…
- Trial name
- NCT04464343
- Testing
- no intervention
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Rupture
Diagnostic Study of ACL Rupture With Anterior Drawer Test at 90° of Hip Flexion
For patients with anterior cruciate ligament rupture, the existing physical examinations have certain limitations. The researchers improved the traditional anterior drawer test in clinical work, maintained the flexion of the knee…
- Trial name
- NCT04957706
- Testing
- anterior drawer test at 90° of hip flexion, Lachman test, anterior drawer test
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University Third Hospital
Cruciate Ligament Reconstruction, Cruciate Ligament Rupture
Biological Potentials in Arthroscopic All-inside Semitendinosus Anterior Cruciate Ligament Reconstruction
A randomized, double-blind, prospective single-center clinical trial evaluating the effect of biological augmentation in anterior cruciate ligament (ACL) reconstruction.
- Conditions
- Cruciate Ligament Reconstruction, Cruciate Ligament Rupture, Cruciate Ligament Injury
- Trial name
- BioACL (NCT07506304)
- Testing
- ACL reconstruction
- Volunteers
- 70 people
- Sponsor
- University Hospital Dubrava
Anterior Cruciate Ligament Rupture, Femoral Nerve Block
FNB in ACL Recon Under GA
The investigators will compare the results of sono-guided femoral nerve block in arthroscopic surgery for anterior cruciate ligament reconstruction under general anesthesia.
- Trial name
- NCT06048848
- Testing
- Sono-guided injection, Ropivacaine injection, Saline injection
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Rupture of Anterior Cruciate Ligament
Analgesic Benefits of Genicular Nerve Blocks of the Posterior Knee for Patients Undergoing ACL Reconstruction
Outpatients scheduled to have ACL surgery typically receive a femoral nerve block to provide analgesia for the front of the knee. Postoperatively, these patients will often report pain in the back of the knee.
- Trial name
- NCT02008617
- Testing
- Bupivacaine, Preservative free normal saline
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Northwestern University
Anterior Cruciate Ligament Rupture
The Comparison of Tunnel Morphology and Graft Healing in Anterior Cruciate Ligament Reconstructions Using Peroneus Longus And Hamstring Tendons
1. Comparison of the grafts using Magnetic Resonance Imaging (MR) to determine whether their maturation and bone integration are different, 2.
- Trial name
- NCT06769711
- Testing
- Surgical procedure using Peroneus Longus for ACL reconstruction., Surgical procedure using Hamstring tendons for ACL reconstruction.
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Karadeniz Technical University
Knee Ligament Injury
Performance and Safety of the Polylactic Interference Screw Used in Anterior Cruciate Ligament Reconstructions
The evaluation of the clinical data has demonstrated the conformity of the Polylactic Interference Screw (PIS), with the relevant essential requirements for its use in orthopaedic applications.
- Trial name
- NCT04122677
- Testing
- Anterior Cruciate Ligament Reconstruction
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Biomatlante
Anterior Cruciate Ligament Rupture
Return to Work and Functional Results of French Soldiers After Anterior Cruciate Ligament Reconstruction
The return to work in the military population after surgical reconstruction of the anterior cruciate ligament (ACL) has been poorly investigated within the French armed forces.
- Trial name
- NCT04668677
- Testing
- On-line questionnaire
- Where
- France
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Anterior Cruciate Ligament Rupture, Pain, Postoperative
Effect of LIA on Postoperative Pain Following ACL Reconstruction
An anterior cruciate ligament (ACL) rupture is one of the most common sport injuries, which typically develops after a sudden knee torsion.
- Trial name
- NCT03873077
- Testing
- local infiltration analgesia
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Torn Anterior Cruciate Ligament (Knee)
Use of Graft Tensioner Device in ACL (Knee) Repair
Compares tension of an ACL graft when using a commercial device vs. the tension of the graft applied by a physician during surgery.
- Trial name
- NCT00221273
- Testing
- ACL surgery
- Volunteers
- 130 people
- Sponsor
- University of British Columbia
Anterior Cruciate Ligament Rupture
Absorbable Interface Screw Clinical Trial
Validation of the safety and efficacy of absorbable interface screws for clinical use
- Trial name
- NCT05431790
- Testing
- Absorbable interface screws manufactured by Natong Biotechnology, Absorbable interface screws manufactured by INION.
- Volunteers
- 86 people
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Injuries
Early Treatment Based Neuroscience Education in Knee
Determine the effecttiveness of a cross-education strength training protocol in a group of subjects with an anterior cruciate ligament surgery.
- Trial name
- ETbNE (NCT05440890)
- Testing
- Best current rehabilitation protocol, Cross-training protocol
- Where
- Spain
- Volunteers
- 29 people
- Sponsor
- University of Malaga
Meniscal Tears, ACL - Anterior Cruciate Ligament Rupture
The Clinical Study of Bone-patellar Tendon-bone and Quasi-anatomical Meniscus Allograft Transplantation Technique
This clinical study investigates the outcomes of bone-patellar tendon-bone and quasi-anatomical meniscus allograft transplantation techniques in patients requiring joint reconstruction.
- Trial name
- BPTB，Meniscus (NCT07088094)
- Testing
- bone-patellar tendon-bone or meniscus allograft transplantation techniques, Quasi-anatomical meniscus allograft transplantation
- Volunteers
- 200 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Rupture of Anterior Cruciate Ligament
Multicenter ACL Revision Study (MARS)
The purpose of this study is to determine the effects of modifiable risk factors on patient-reported quality of life, physical activity levels, and risk of early osteoarthritis following revision anterior cruciate ligament (ACL)…
- Trial name
- MARS (NCT00625885)
- Where
- 49 sites in United States, Canada
- Volunteers
- 1,234 people
- Sponsor
- Vanderbilt University Medical Center
ACL Injury, ACL - Anterior Cruciate Ligament Rupture
Improving ACL Reconstruction Outcomes: CBPT
The overall objective of this study is to conduct a two-group randomized trial to examine the efficacy of cognitive-behavioral based physical therapy (CBPT) for improving knee function, return to sport, and quality of life…
- Conditions
- ACL Injury, ACL - Anterior Cruciate Ligament Rupture, ACL Sprain, ACL Tear
- Trial name
- NCT03243162
- Testing
- CBPT-ACLR, Education
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Vanderbilt University Medical Center
Anterior Cruciate Ligament Rupture
A Clinical Trial of the Round-tunnel and Flat-tunnel Technique of ACL Reconstruction
This study intends to perform round-tunnel and flat-tunnel ACL reconstruction technique in 144 patients, and compare the clinical outcomes of the two surgical procedures through follow-up.
- Trial name
- NCT04953676
- Testing
- round tunnel technique, flat tunnel technique
- Volunteers
- 144 people
- Sponsor
- Peking University Third Hospital
Blood Flow Restriction, ACL Tear
Blood Flow Restriction Training (BFR) in an Adolescent Population
While there are a number studies that have reported on the use of BFR in the adult population, there is limited information about the use of BFR in the adolescent population.
- Conditions
- Blood Flow Restriction, ACL Tear, ACL Injury
- Trial name
- NCT04285879
- Testing
- Blood Flow Restriction using Delfi Personalized Tourniquet System
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Connecticut Children's Medical Center
Muscle Weakness, Anterior Cruciate Ligament Rupture
Does Gabapentin Reduce Quadriceps Muscle Weakness After Anterior Cruciate Ligament Reconstruction?
Anterior cruciate ligament (ACL) injury is a common sport injury in both professional and recreational athletes. Furthermore, persistent quadriceps weakness and wasting are frequently observed after anterior cruciate ligament…
- Trial name
- NCT03496389
- Testing
- Gabapentin, Tramadol, Panadol
- Volunteers
- 30 people
- Sponsor
- Hospital Authority, Hong Kong
ACL Injury
Multimodal Assessment of Knee Conditions in Rehabilitation
The purpose of this study is to assess ACL injury and other pathological knee conditions from the combination of signals that are known to provide information on the knee joint.
- Trial name
- NCT03608189
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- University of Oulu