Clinical trials: Ligament Tear Knee
ACL Injury, ACL Tear
The Pediatric ALL Evaluation and Trial
The overall aim of this multicenter RCT is to determine whether concomitant ALL reconstruction in children undergoing and ACL reconstruction will longitudinally result in a lower rate of graft failure than ACL reconstruction…
- Trial name
- PALLET (NCT04825587)
- Testing
- Patients will be randomized into one of two study arms: (1) concomitant ACL and ALL reconstruction or (2) ACL reconstruction alone.
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Anterior Cruciate Ligament Rupture, Tendon Injuries
Shear-Wave Elastography of Regenerated Hamstring Tendons After ACL Reconstruction (SWE-ACL)
Anterior cruciate ligament (ACL) reconstruction using autologous hamstring tendon grafts is a commonly performed procedure. Although the semitendinosus and gracilis tendons demonstrate regeneration at the donor site, the…
- Conditions
- Anterior Cruciate Ligament Rupture, Tendon Injuries, Muscle Weakness
- Trial name
- SWE-ACL (NCT07555782)
- Testing
- Shear-Wave Elastography Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
ACL Tear
Comparison of Methods in Post Operative Knee Arthroscopy Rehabilitation
The aim of this study is to investigate the efficacy of blood flow restriction (BFR) therapy in post-operative rehabilitation following knee arthroscopy for primary ACL reconstruction.
- Trial name
- ACL BFR (NCT05735236)
- Testing
- BFR Cuff
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of Colorado, Denver
Muscle Atrophy, Proximal, Muscle Atrophy
Ultrasound for Rectus Femoris Measurement
Postoperative protocols for orthopedic procedures on the lower limb often require a period of immobilization to protect the surgical site.
- Conditions
- Muscle Atrophy, Proximal, Muscle Atrophy, ACL Tear, Quadriceps Muscle Atrophy
- Trial name
- NCT04105816
- Testing
- 892.1550 Ultrasonic pulsed doppler imaging system, Thigh circumference measurement
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Robert Westermann
ACL Injury
Influence of Combined Double-Bundle ACL Reconstruction With Lateral Retinacular Release to Prevent Patellofemoral Malalignment in Isolated ACL Rupture
Anterior knee pain which might be due to patellofemoral malalignment is an inevitable post operative complication after an ACL reconstruction (ACLR).
- Trial name
- NCT06004297
- Testing
- ACL reconstruction
- Where
- Indonesia
- Volunteers
- 100 people
- Sponsor
- Universitas Indonesia
Rupture of Anterior Cruciate Ligament
COX-2 Inhibitor Versus Glucocorticoid Versus Both Combined
Recent studies on molar surgery have shown that a combination of a glucocorticoid and NSAID or COX-2 selective inhibitor gives better pain relief than either of the drugs used separately.
- Trial name
- NCT01361789
- Testing
- parecoxib, valdecoxib, etoricoxib, Dexamethasone, parecoxib, valdecoxib, parecoxib and dexamethasone
- Where
- Norway
- Volunteers
- 93 people
- Sponsor
- Asker & Baerum Hospital
Anterior Cruciate Ligament Rupture
Pain Management of ACL Reconstruction
This study will compare the outcome of pain interventions that are considered standard of care during the surgical treatment of ACL injuries.
- Trial name
- NCT03365908
- Testing
- Adductor Canal Nerve Block, Ropivacaine injection
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, Davis
Anterior Cruciate Ligament Rupture
Are Opioids Needed After ACL Reconstruction
As the public health sector continues to confront the opioid epidemic, orthopaedic surgeons must revisit pain management protocols to reduce unnecessary opioid prescriptions.
- Trial name
- NCT04285853
- Testing
- Oxycodone
- Where
- 3 sites in United States
- Volunteers
- 98 people
- Sponsor
- Emory University
Knee Pain
Validity and Reliability of Video-Based Functional Physiotherapy Assessment of Subacute Knee Injuries
This study aims to validate a function-based physiotherapy assessment for subacute knee pain without using specific knee tests. Assessments are conducted either in-person or via video consultations in primary care.
- Trial name
- NCT07212920
- Testing
- Physiotherapy digital assessment, Physiotherapy assessment - only functional tests
- Where
- 3 sites in Sweden
- Volunteers
- 138 people
- Sponsor
- Vastra Gotaland Region
ACL - Anterior Cruciate Ligament Rupture
Assessment of NEURO-K-STARTS Following Primary Anterior Cruciate Ligament (ACL) Reconstruction
Anterior cruciate ligament (ACL) reconstruction is the major treatment option for ACL injuries. Despite this, recurrence rates are high.
- Trial name
- NEURO-K-STARTS (NCT07659613)
- Testing
- NEURO-K-STARTS
- Where
- France
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Complete Tear, Knee, Anterior Cruciate Ligament
A Study to Compare Two Techniques for the Reconstruction of the Anterior Cruciate Ligament
This is a prospective and randomized trial to compare two different techniques used in normal practice for the reconstruction of the anterior cruciate ligament in arthroscopy.
- Trial name
- ACL (NCT03746470)
- Testing
- ACL reconstruction preserving insertion, ACL reconstruction detaching insertion
- Where
- 2 sites in Italy, Switzerland
- Volunteers
- 85 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Complete Tear, Knee, Anterior Cruciate Ligament
Gait Rehabilitation Following an Anterior Cruciate Ligament Reconstruction
A randomized control trial where subjects following an anterior cruciate ligament reconstruction will be randomized to either a control group who will receive the normal rehabilitation or an experimental group who will perform a…
- Trial name
- NCT02930239
- Testing
- Gait rehabilitating with reduced bodyweight, Standardized rehabilitation following an anterior cruciate ligament reconstruction at Linkoping University Hospital
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Linkoeping University
Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction
Clinical and Functional Outcomes After ACL Reconstruction Versus Primary Repair
The anterior cruciate ligament (ACL) is the primary structure responsible for controlling anterior-posterior translation and rotational stability of the knee joint.
- Conditions
- Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction, Isokinetic Test
- Trial name
- NCT07318272
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Gazi University
Anterior Cruciate Ligament Tear, Posterior Cruciate Ligament Tear
Effect of Physical Therapy and/or Platelet Rich Plasma Injection in People With Knee Cruciate Ligament Injuries
Background: The anterior cruciate ligament(ACL) , one of the major ligaments in the knee joint which connects the posterior aspect of the lateral femoral condyle to the anterior intercondylar area of the tibia.
- Trial name
- NCT06233305
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taipei Hospital, Ministry of Health and Welfare
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Exploring Prolonged AMR in ACL Reconstructed Patients
The goal of this observational study is to explore the significance of subject-reported outcomes and clinical parameters in relation to the occurence of prolonged presence of arthrogenic muscle responses (AMR) in anterior…
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, ACL
- Trial name
- NCT06430775
- Where
- Belgium
- Volunteers
- 190 people
- Sponsor
- University Ghent
Knee Injury
Dynamic Stability of the Anterior Cruciate Ligament (ACL) Deficient Knee
The study that is registered in ClinicalTrials is a part study of an overall study with the title 'Dynamic stability of the ACL-injured knee'.
- Trial name
- NCT00696319
- Testing
- Exercise protocol with perturbation exercises., Exercise protocol with traditional exercises for stability and balance.
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Ullevaal University Hospital
Anterior Cruciate Ligament Tear
IPACK Versus Popliteal Sciatic Nerve Block in ACL Reconstruction
This is a prospective study comparing femoral nerve block plus sciatic nerve block to femoral nerve block plus infiltration of the posterior knee capsule (IPACK) in patients undergoing arthroscopic anterior cruciate ligament…
- Trial name
- NCT03983941
- Testing
- Ropivacaine injection
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Sujana Dontukurthy
Rupture of Anterior Cruciate Ligament
Study of the Anatomical Direct Insertion Anterior Cruciate Ligament Reconstruction
The purpose of the study is to study the effect of anatomical direct insertion ACL reconstruction compared with conventional anatomical ACL reconstruction.
- Trial name
- NCT02833454
- Testing
- direct insertion anterior cruciate ligament reconstruction, single bundle anterior cruciate ligament reconstruction, double bundle anterior cruciate ligament reconstruction
- Volunteers
- 320 people
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Rupture
LIBRE (Ligamys, Internal Bracing, REconstruction) Study: Comparing Three Surgery Techniques After an Acute ACL Rupture.
Single-blind, multi-centre, prospective, randomized controlled trial comparing Ligamys Anterior Cruciate Ligament (ACL) repair, Internal Bracing ACL repair and conventional ACL reconstruction for relative clinical efficacy and…
- Trial name
- LIBRE (NCT03441295)
- Testing
- Dynamic Intraligamentary Stabilization, Internal Brace Ligament Augmentation, ACL Reconstruction
- Where
- 3 sites in Belgium
- Volunteers
- 95 people
- Sponsor
- University Hospital, Antwerp
ACL Tear
Quadriceps Strengthening ACL Reconstruction
The purpose of this study is to characterize quadriceps function and squat biomechanics during the early strengthening phase in adolescent patients undergoing a standardized combined neuromuscular electrical stimulation (NMES)…
- Trial name
- ACL (NCT07015541)
- Testing
- NMES and BFR, Standard physical therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stanford University