Clinical trials: Light; Therapy, Complications
Crying, Sleep
Cycled Light and Crying of Preterm Infants
This study shows that cycled light during neonatal care reduces infant's fussing and crying behavior at 5 and 11 weeks corrected age and improves growth during neonatal care.
- Trial name
- NCT01513226
- Testing
- Cycled light
- Volunteers
- 37 people
- Sponsor
- University Children's Hospital, Zurich
Lower Abdominal Surgery, Pelvic Surgery
Objective to Evaluate the Safety and Effectiveness of LED Light Source System for Endoscopy in Ureteral Radiography
This clinical trial is a prospective, multi-center, single-blind, parallel, randomized controlled superiority clinical trial. The trial will be carried out in 5 centers, involving 120 subjects as estimated who will be divided…
- Trial name
- IRIS (NCT04561414)
- Testing
- LED light source system for endoscope, Ureteral stent (Cook Ireland Ltd.)
- Where
- 4 sites in China
- Sponsor
- Stryker Orthopaedics
Delirium, Postoperative Cognitive Dysfunction
Biomarkers Associated With Postoperative Cognitive Dysfunction
Loss of cognitive function after major surgery is a significant risk in older people. It can occur acutely in the days after surgery as delirium or in months to years later as a persistent reduction in brain function termed…
- Conditions
- Delirium, Postoperative Cognitive Dysfunction, Cognitive Decline, Cognitive Impairment
- Trial name
- NCT05464355
- Testing
- Intraoperative electroencephalography recording, Neurofilament light chain measurement, Tau protein measurement
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- University of Oxford
Emergence Delirium, Anesthesia Emergence Delirium
Effect of Monochromatic Light on Incidence of Emergence Delirium in Children
Emergence delirium/emergence agitation (ED/EA) is a behavioral phenomenon of unclear etiology consisting of short lived behavioral changes that can be both traumatic to families and pose a safety risk to patients and staff.
- Trial name
- NCT03285243
- Testing
- Monochromatic blue light
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Bacterial Vaginosis, Vulvovaginal Candidiases
Light Treatment of Vaginal Infections in Reproductive Age Women
Antimicrobials have helped in managing vaginal dysbiotic conditions such as bacterial vaginosis (BV) and vulvovaginal candidiasis (VVC).
- Trial name
- NCT06985433
- Testing
- Vaginal light therapy - Once, Vaginal Light Therapy - Twice
- Where
- Denmark
- Volunteers
- 38 people
- Sponsor
- UVISA Health ApS
End Stage Renal Disease
Light Therapy in End Stage Kidney Disease
The goal of this clinical trial is to test light therapy in patients with end stage kidney disease who are receiving hemodialysis. The main aim is to determine if light therapy decreases fatigue severity.
- Trial name
- NCT06310161
- Testing
- Bright light, Dim Light
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Pennsylvania
Multiple Myeloma, Chronic Kidney Disease
Optimising Renal Outcome in Myeloma Renal Failure
The purpose of this study is to compare the effectiveness of bortezomib versus thalidomide in reducing free light chains in the blood of myeloma patients.
- Trial name
- OPTIMAL (NCT02424851)
- Testing
- Bortezomib, Thalidomide, Bendamustine
- Where
- 9 sites in United Kingdom
- Volunteers
- 31 people
- Sponsor
- Oxford University Hospitals NHS Trust
Childhood-onset Systemic Lupus Erythematosus, Lupus Nephritis (LN)
Childhood-onset Lupus Nephritis Initial Glucocorticoid-dose Harmonization Trial (LIGHT Trial)
Childhood-onset systemic lupus erythematosus (cSLE) is a severe chronic autoimmune disease with a high burden of major-organ involvement.
- Trial name
- LIGHT (NCT07719140)
- Testing
- High-dose prednisone, Low-dose prednisone
- Where
- 8 sites in China
- Volunteers
- 198 people
- Sponsor
- Peking Union Medical College Hospital
Benign Prostate Hyperplasia, Urinary Retention
Prostatic Artery Embolization Versus 532 nm Green Light PVP for Catheterized Patients
The primary objective is to assess whether prostatic artery embolization has a similar efficacy and safety profile as GreenLight PVP in treating patients with urinary retention secondary to benign prostate hyperplasia (BPH).
- Trial name
- NCT02006303
- Testing
- Green light PVP, Prostatic artery embolization
- Where
- 2 sites in Canada
- Volunteers
- 73 people
- Sponsor
- Royal Victoria Hospital, Canada
Renal Cell Carcinoma
The Pharmacological Effects of Using Cabozantinib With a Light Breakfast
Cabozantinib is a drug which is used to treat metastasized kidney cancer. While it works well, it has a lot of side effects and is quite expensive (€213,- every tablet, €6403,- every month).
- Trial name
- Skippy 1 (NCT05263245)
- Testing
- Light breakfast
- Where
- 2 sites in Netherlands
- Volunteers
- 12 people
- Sponsor
- dr. Tom van der Hulle
Bladder Cancer
Longer-term Recurrence Rates in Patients With Bladder Cancer After Hexvix (Cysview)Fluorescence Cystoscopy/TURB
The study is intended to investigate whether the improved initial detection and resection of bladder cancer lesions in patients with non-muscle invasive bladder cancer with Hexvix (Cysview) fluorescence cystoscopy/TURB will lead…
- Trial name
- NCT01166230
- Where
- 24 sites in United States, Austria and 3 more
- Volunteers
- 551 people
- Sponsor
- Photocure
Gastrostomy Complications
LASER THERAPY IN GASTRIC STOMA INJURIES OF CHILDREN AND ADOLESCENTS
Compare the healing time of lesions in the mucosa of the gastric stoma of children and adolescents using laser therapy versus conventional treatment with protective barrier powder.
- Trial name
- NCT04863196
- Testing
- Laser therapy Treatment Group, Barrier Dust Treatment Group
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- University of Sao Paulo General Hospital
Bladder Cancer
Comparison Study of Narrow Band Imaging Versus White Light Resection in Patients With Bladder Tumors/Cancer
The purpose of this study is to compare the recurrence rate at 1 year following Narrow Band Imaging and trans-urethral resection of bladder tumor with White Light and TURB in patients with non-muscle invasive bladder cancer.
- Trial name
- NCT01180478
- Testing
- White Light, Narrow Band Imaging
- Volunteers
- 965 people
- Sponsor
- Clinical Research Office of the Endourological Society
Diabetic Polyneuropathy
Serum Neurofilament Light Chain Levels and Neuropathy Severity in Diabetic Polyneuropathy
Diabetic polyneuropathy (DPN) is one of the most common chronic complications of diabetes mellitus and is characterized by peripheral nerve damage caused by long-term hyperglycemia.
- Trial name
- DPN-NFL (NCT07480330)
- Testing
- Blood Sample Collection and Clinical Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Light; Therapy, Complications
PhotoDynamic Therapy for Line Infection Prevention (PLIP): Pilot Study on Healthy Volunteers.
We are evaluating the effect of methylene blue and visible light activation on the microbiome of the skin.
- Trial name
- NCT01981460
- Testing
- Methylene blue and light treatment
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Leg Ulcers Venous, Dehiscence, Surgical Wound
Blu Light for Ulcers Reduction
Multi-center study on the effectiveness of treatment with a blue light medical device (EmoLED) in the reduction of ulcer surface in 10 weeks.
- Trial name
- BLUR (NCT04018924)
- Testing
- Illumination with blue light (400-430nm) for 60 seconds with a power density of 120mW/sqcm (EmoLED device)
- Where
- 7 sites in Italy
- Volunteers
- 90 people
- Sponsor
- Emoled
Anovulation
Effect of Bright Light on Sex Hormones and Ovulation in Humans
The study investigated whether bright artificial light may influence menstrual cycle and ovulation conclusively, and what underlying hormonal changes for this effect are.
- Trial name
- NCT00327366
- Testing
- Light therapy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Russian Academy of Medical Sciences
Diabetic Neuropathy
NIR- and Multifrequent Impedance Spectroscopy on the Skin in Type 1 Diabetes
The aim of the study is to examine the suitability to detect diabetic neuropathy using NIR and impedance.
- Trial name
- NIR (NCT01707979)
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lise Tarnow
Phototherapy Complication, Photobiology
Violet-Blue Light Inactivation of Bacteria in Chronic Wounds
This four-week prospective clinical investigation will assess the safety and feasibility of a medical device without CE-marking. The medical device is a light-emitting-diode (LED) and is manufactured by VulCur MedTech Aps.
- Conditions
- Phototherapy Complication, Photobiology, Light Treatment; Complications, Wound Infection
- Trial name
- NCT05739058
- Testing
- Violet-Blue Light Treatment / FlashHeal Device
- Where
- Denmark
- Volunteers
- 22 people
- Sponsor
- Bispebjerg Hospital
Cervical Cancer, Chronic Myeloproliferative Disorders
Dalteparin to Prevent Complications in Cancer Patients Receiving Chemotherapy Through a Catheter
RATIONALE: The use of dalteparin may be able to prevent complications caused by the use of a catheter to supply chemotherapy to cancer patients. It is not yet known if dalteparin is effective in reducing these complications.
- Conditions
- Cervical Cancer, Chronic Myeloproliferative Disorders, Leukemia, Lymphoma
- Trial name
- NCT00006083
- Testing
- Fragmin
- Where
- United States
- Sponsor
- Jonsson Comprehensive Cancer Center