Clinical trials: Light
Vision Satisfaction in Bright Light
ACUVUE® OASYS With Transitions™ Light Intelligent Technology™ Clinical Performance Registry
This registry study is a one-year, one-visit, observational, prospective, open-label, two-arm, multi-center, multi-national, post-market study of approximately 300 patients who have recently been fitted with the ACUVUE® OASYS…
- Trial name
- NCT04116736
- Testing
- ACUVUE® OASYS with Transitions™, Silicone Hydrogel Contact Lens
- Where
- 22 sites in Spain, United Kingdom
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Chronic Obstructive Pulmonary Disease (COPD)
Validation of Structured Light Plethysmography - Health and Disease
Validation of Structured Light Plethysmography (SLP) in patients with conditions such as Chronic Obstructive Pulmonary Disease (COPD) that effect breathing and in healthy participants.
- Trial name
- SLP-RespDis (NCT02626468)
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pneumacare Ltd
Acne Vulgaris
A Study to Evaluate the Potential of Tazarotene Foam to Cause a Reaction When Applied to the Skin and Exposed to Light on Healthy Volunteers
The purpose of this study is to evaluate the potential of Tazarotene Foam to induce a phototoxic reaction when exposed to UV and VIS light on skin of healthy volunteers.
- Trial name
- NCT01115322
- Testing
- Tazarotene Foam without irradiation, Tazarotene Foam with UVA and UVB irradiation, Tazarotene Foam with UVA, UVB, and visible light
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Stiefel, a GSK Company
Obesity
Effects of Red Light LED Therapy on Body Contouring
Red light laser therapy using 635nm red light laser technology has previously been shown to cause lipolysis in subcutaneous fat as a non-surgical method to promote weight loss and body contouring.
- Trial name
- NCT03470272
- Testing
- FB Professional LED Red light therapy, Effects of Red Light LED Therapy on Body Contouring
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Manamed Inc.
Healthy Adult Subjects, Healthy Elderly Subjects
Multiple Dose Study Of BIIB118 (PF-05251749) In Healthy Volunteers
This is the first clinical trial to evaluate ascending multiple oral doses in healthy adult and healthy elderly subjects to characterize the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of BIIB118
- Trial name
- NCT02691702
- Testing
- BIIB118, Melatonin
- Where
- 2 sites in United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Biogen
Hydration Status, Substrate Metabolism During Exercise
The Effect of Hydration Status on Substrate Oxidation at Rest and During Light and Moderate Exercise
Metabolic flexibility is the ability to properly switch between fat and carbohydrate stores to use for energy under different conditions (rest, feeding, exercise).
- Trial name
- NCT07298863
- Testing
- Part 1 - Exercise Trial, Part 1 - Experimental Trial, Part 2 - Oral Glucose Tolerance Test
- Where
- 2 sites in United States, Canada
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Hyperglycemia, Postprandial
Evaluation of OxxyneaGS in Acute Glycemic Regulation on Light Hyperglycemic Subjects
This study aims to evaluate and select the best combination of polyphenol and white kidney bean ingredients in the acute glycemic modulation after a complete meal by measuring blood glucose and insulin.
- Trial name
- NCT04914416
- Testing
- Verum T1, Verum T2, Verum T3
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fytexia
Androgenetic Alopecia, Hair Loss
Low Level Light Device as a Primary Therapy for Androgenetic Alopecia
The purpose of this research is to study the safety and effectiveness of a light therapy device for human hair growth. This device, called the GENIX, is a type of cold, or non-heat producing light emitting diode (LED) that will…
- Conditions
- Androgenetic Alopecia, Hair Loss, Thinning Hair, Balding
- Trial name
- NCT04558242
- Testing
- Genix
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kiierr International, LLC
Helicobacter Pylori
Feasibility Study of Phototherapy System to Treat H Pylori
This purpose of this study is to determine whether phototherapy can be used to safely and effectively treat H pylori.
- Trial name
- NCT00306280
- Testing
- Phototherapy
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- LumeRx
Inflammation, Skin Abnormalities
Effects of Bend Beauty's Anti-Aging Formula on Inflammatory Markers
This is a phase IV, randomized, double-blind, placebo-controlled, three-arm, parallel intervention study including three groups of 25 subjects between 35-65 years of age, treated with either Bend Beauty's Anti-Aging Formula, fish…
- Conditions
- Inflammation, Skin Abnormalities, Skin Pigment, Inflammatory Response
- Trial name
- BENCHMARK (NCT03862872)
- Testing
- Anti-Aging Formula, Control Fish Oil
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bend Beauty Inc.
Healthy
Clinical Evaluation of the Photoallergy Potential of Atralin Gel
To assess the potential of tretinoin gel 0.05% and its vehicle to produce photoallergic reactions, measured as skin reactions following induction and challenge.
- Trial name
- NCT00603772
- Testing
- Atralin (tretinoin) gel, 0.05%
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Coria Laboratories, Ltd.
Visible Light Exposure on Healthy Back Skin
Photoprotection Efficacy of Different Topical Agents Under Visible Light Exposure
To evaluate the protective effect of seven sunscreens on the pigmentation induced by visible light in comparison to an untreated control zone in healthy volunteers
- Trial name
- NCT06796153
- Testing
- Visible Light Exposure - Treated zones, Visible Light Exposure - Untreated zone
- Where
- Romania
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Pigment; Lesion, Lesion; Vascular
Image Data Collection of Tanned Skin During Phototherapy Treatment Using a Multi-spectral Camera
This is a prospective, observational, single-center, image collection study. Any patient who arrived at the phototherapy clinic for the first time, regardless of this study, and is prescribed a total of 30 treatments can be…
- Trial name
- NCT05692544
- Testing
- Phototherapy treatment
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Lumenis Be Ltd.
Quality of Life, Fatigue
Safety and Feasibility of Polychromatic Light Emitting Diode for Peripheral Catheter Illumination During Peripheral Intravenous Delivery of Normal Saline
This study uses a prospective non-randomized, non-controlled design. Five-hundred (500) subjects having previously received a peripheral intravenous therapy will be enrolled into a single treatment group.
- Trial name
- NCT02785133
- Testing
- UVL1000 Treatment Station, Normal Saline Solution, Peripheral Catheterization
- Where
- United States
- Volunteers
- 3,063 people, healthy volunteers welcome
- Sponsor
- UVLrx Therapeutics
Healthy
Study To Assess The Effect Of PF-04531083 On Heat Pain In Healthy Volunteers With Ultraviolet Light Sensitized Skin
PF-04531083 has been shown to reduce the amount of heat pain experienced by rats with skin that has been sensitized to heat by ultraviolet light. This study is designed to see if this is also true in man.
- Trial name
- NCT01127906
- Testing
- PF-04531083 100mg, PF-04531083 2000mg, Oxycodone 20mg
- Where
- Belgium
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Pfizer
Study the Potency of Sunscreen to Protect Against the Pigmentation Induced by Visible Light Exposure on Healthy Back Skin
Evaluate the Photoprotection Efficiency of Sunscreen Formulas Under Visible Light Exposure
To evaluate the protective effect of three sunscreens on the pigmentation caused by visible light in comparison to an untreated control zone in healthy volunteers.
- Trial name
- NCT06796088
- Testing
- Treated zones exposed to Visible Light source, Untreated zone exposed to Visible Light source
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Pigmentation, Redness
Photoprotection Efficacy With Sunscreen Formulas Containing the Cyclic Merocyanine Long-UVA Absorber MCE Under UV Day Light Exposure
To evaluate the photo-protector effect of BC_3 (E212657) formulated in SPF compared to SPF alone on UV Day Light induced pigmentation in healthy volunteers
- Trial name
- NCT04866797
- Testing
- cyclic merocyanine
- Where
- Romania
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Chalazion
Evaluation of Effectiveness and Safety of Intense Pulsed Light Treatment for Chalazion
To study the effectiveness and safety of IPL treatment for Chalazion
- Trial name
- NCT07039461
- Testing
- OptiLIGHT
- Where
- 2 sites in United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Lumenis Be Ltd.
Healthy
Effect of Meal Composition and Timing on Evobrutinib Bioavailability
This study will evaluate the Pharmacokinetics (PK) of the Phase II tablet formulation of Evobrutinib under fasted conditions, within 30 minutes after start of a light meal, one hour prior to start of a low-fat meal, and 2 hours…
- Trial name
- NCT03934502
- Testing
- Evobrutinib
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Healthy
Clinical Trial to Evaluate UV-light-induced Allergic Skin Reactions After Application of Delgocitinib Cream
Participants will have study medicine applied by site staff- delgocitinib cream or vehicle, and then exposed to UV light. The trial is designed to find out if delgocitinib cream can cause skin photoallergy after UV-light exposure…
- Trial name
- NCT04807751
- Testing
- Delgocitinib cream, Delgocitinib cream vehicle
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- LEO Pharma