Clinical trials: Light
Effects of Blue-light Blocking Lens on Visual Functions
Effects of Blue-light Blocking Lens on Visual Functions
Working Hypothesis: The blue-light blocking lens has no effect on the contrast sensitivity, accommodative response, color vision, and subjective grading of the quality of life and vision.
- Trial name
- NCT02821403
- Testing
- clear lens with regular coating, regular coating lens with yellow tint, clear lens with blue-light blocking coating
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Relapsing Remitting Multiple Sclerosis, Progressive Multiple Sclerosis
Serum Neurofilaments and GFAP in Atypical Multiple Sclerosis
Idiopathic inflammatory disorders of the central nervous system include various disorders of which multiple sclerosis is the most common.
- Conditions
- Relapsing Remitting Multiple Sclerosis, Progressive Multiple Sclerosis, Controls, Multiple Sclerosis
- Trial name
- AMIS (NCT04201470)
- Testing
- Blood withdrawal, MRI, Neurologic / neuropsychologic tests - Patients
- Where
- France
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
COVID-19 Prevention
Study to Evaluate Efficacy, Immunogenicity and Safety of the Sputnik-Light
The study Global sponsor is planning several parallel studies of Sputnik-Light vector vaccine across the globe in United Arab Emirates, Russia and possibly in other countries in case of confirmation associated with the same…
- Trial name
- SPUTNIK-LIGHT (NCT04741061)
- Testing
- Sputnik Light
- Where
- 15 sites in Russia
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation
Myopia
Sustained Effect of Red-light Therapy for Myopia Control: A 2-Year Post-Trial Follow-up Study
To evaluate the long-term efficacy and safety of red-light therapy for myopia control over 2 years, and the potential rebound effect after treatment cessation.
- Trial name
- NCT06232161
- Testing
- Red-light therapy device, Spectacles
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Food Insecurity, Dietary Quality
Behavioral Economics to Implement Nutrition Ranking in Food Pantries
The goal of this randomized controlled trial is to test whether using behavioral economic strategies to promote healthy food choices on a food bank's online ordering platform increases the use of the traffic light nutrition…
- Conditions
- Food Insecurity, Dietary Quality, Behavioral Economics, Implementation Science
- Trial name
- NCT05854212
- Testing
- Behavioral economics-enhanced user interface
- Where
- United States
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
White Spot Lesion of Tooth, Orthodontic Malocclusion
A Comparative Assessment of Orthodontic Treatment Outcomes Using the Quantitative Light-Induced Fluorescence Method
The aim of this 2-arm parallel trial was to evaluate enamel demineralization after an indirect bonding technique in comparison to a direct bonding technique group using the quantitative light-induced fluorescence method.
- Trial name
- QLF (NCT03738839)
- Testing
- Quantitative Light-Induced Fluorescence, Direct bonding, Indirect bonding
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Glaucoma
Altered Non-Visual Photoreception in Patients With Glaucoma: Impacts on Sleep, Alertness, Mood, and Cognition
The goal of this study is to understand how light sensitivity in the eye affects sleep, mood, alertness, and cognition in adults with glaucoma compared to healthy individuals aged 45-75 years.
- Trial name
- EyeQ (NCT07364929)
- Testing
- Full-spectrum light exposure, Standard indoor light exposure (Control)
- Where
- 2 sites in Singapore
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Periorbital Disorder
Treatment of Periorbicular Hyperchromia Comparing 10% Thioglycolic Acid Peeling Versus Pulsed Intense Light
Periorbital hyperchromia (POH) or periorbital hyperpigmentation, commonly known as "dark circles", is a relatively common condition and a frequent reason for dermatological consultation.
- Trial name
- NCT03238105
- Testing
- Thioglycolic Acid, Intense Pulsed Light
- Where
- Brazil
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Insomnia, Sleep
Blue Blockers at Night and Insomnia Symptoms
Under entrained conditions, humans maintain a consolidated nocturnal sleep episode that coincides with environmental darkness and endogenous melatonin secretion.
- Trial name
- NCT02698800
- Testing
- Blue blocking (BB) lenses, Clear lenses
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Columbia University
Stress
Chronobiological and ACT-based Training to Handle Stress at Work
The aim of the present project is to combine "Acceptance and Commitment Therapy" and "sleep hygiene + light-therapy (so-called chronotherapy)" serially in a sample of employees to reduce levels of subjective exhaustion.
- Trial name
- NCT04290117
- Testing
- Acceptance and Commitment Training, Sleep Hygiene and bright light in the morning
- Where
- Switzerland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Psychiatric Hospital of the University of Basel
Cardiovascular Disease
Dark Chocolate and Platelet Function in Humans
Cardiovascular disease is a major cause of mortality worldwide and responsible for one out of three global deaths. A main characteristic of cardiovascular disease is impaired blood flow and formation of blood clots.
- Trial name
- NCT01099150
- Testing
- Dark chocolate enriched in flavan-3-ols and procyanidins, Standard dark chocolate, White chocolate
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Pulp Disease, Dental, Dental Caries
Dentin Bridge Formation After Indirect Pulp Capping With Bioactive Glass Incorporated in Resin Composite and Its Adhesive in Comparison With Light Cured Calcium Hydroxide
The aim of this study is to evaluate the effect of application of bioactive glass in different protocols on the formation of dentin bridge after indirect pulp capping using resin composite with its adhesive both are containing…
- Trial name
- NCT04274920
- Testing
- Bioactive Glass, Light cured calcium hydroxide
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Circadian Rhythm Sleep Disorder, Delayed Sleep Phase, Sleep
The Effects of a Blue Monochromatic Light Intervention on Evening-type Individuals' Sleep and Circadian Rhythms
The present project is aimed to contribute with new knowledge concerning how light conditions in the physical environment can be manipulated to alter the sleep and circadian rhythms of individuals with an evening-type circadian…
- Trial name
- NCT03758768
- Testing
- Blue light exposure, Full spectrum light exposure
- Where
- Norway
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Acne Vulgaris
Open-label Safety and Tolerability Study of LTS-PDT in Healthy Volunteers
The purpose of this study is assess the safety and tolerability of lemuteporfin topical solution (LTS) with exposure to red light (PDT), when applied to the backs of healthy volunteers.
- Trial name
- NCT01830764
- Testing
- Red Light (PDT)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Dermira, Inc.
Bruxism
Evaluation of Salivary Biomarkers in Individuals With Bruxism
The goal of this observational study is to evaluate salivary biomarkers and perceived stress in adults with bruxism compared with healthy individuals.
- Trial name
- BRUXSAL (NCT07702019)
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Giresun University
Relapse Remitting Multiple Sclerosis
Early Versus Delayed Start of Ocrevus Zunovo for Relapsing Multiple Sclerosis
This study will compare starting Ocrevus Zunovo soon after an active episode of relapsing multiple sclerosis (MS) with starting it later.
- Trial name
- STAT (NCT07878923)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Oklahoma Medical Research Foundation
Heavy Smoking
Bronchoscopy Screening for High-risk Population of Lung Cancer With Severe Smoking With Negative LDCT Screen
Based on the previous work of LDCT screening, in order to improve the screening rate of central lung cancer for LDCT negative and severe smokers, the investigators plan to conduct China's first large-scale fluorescent…
- Trial name
- NCT04413669
- Testing
- white light bronchoscopy & autofluorescence bronchoscopy
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Jiayuan Sun
Sedentary Lifestyle
The Health Action Process Approach and Movement Patterns in Adult Office Workers
Societal changes have resulted in reduced demands to be active and increased daily time spent sitting. Excessive sitting has been shown to be a health hazard.
- Trial name
- NCT03091686
- Testing
- HAPA SB Intervention Slideshow, HAPA MVPA Attention-Control Slideshow
- Where
- Canada
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Diabetes Mellitus, Type 2, Glucose Intolerance
The Effects of Light on Glucose Metabolism
This study evaluates the effect of bright light on postprandial blood glucose metabolism in obese subjects with impaired fasting glucose and/or impaired glucose tolerance.
- Conditions
- Diabetes Mellitus, Type 2, Glucose Intolerance, Prediabetic State
- Trial name
- NCT03829982
- Testing
- Exposure to bright light during the day, Exposure to dim light during the day
- Where
- Netherlands
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Neonatal Jaundice, Atopic Dermatitis
Skin Care Strategies for Neonatal Jaundice Phototherapy to Prevent Atopic Dermatitis in Moderate and Severe Infants
Atopic Dermatitis (AD) is a common chronic, recurrent, and inflammatory skin disease in children. The incidence of moderate to severe AD in infants aged 1-12 months in our country is as high as 25.41%, which is related to…
- Trial name
- NCT05178433
- Testing
- Use baby moisturizers by NeoChine
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shanghai First Maternity and Infant Hospital