Clinical trials: Light
Tooth Bleaching
Safety and Efficacy of a 6% Hydrogen Peroxide Tooth Bleaching Agent
Bleaching protocol In each session, volunteers received prophylaxis with pumice powder and water. Then, gingival tissue was protected using a light-cured resin gum barrier applied according to the manufacturer's instructions…
- Trial name
- NCT02353611
- Testing
- 6% hydrogen peroxide, 35% hydrogen peroxide
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Chile
Polymorphic Light Eruption, Psoriasis
Regulatory T Cells (Tregs) in Polymorphic Light Eruption
Polymorphic light eruption (PLE) is a photodermatosis with an extremely high prevalence, particularly among young women (up to 20%).
- Conditions
- Polymorphic Light Eruption, Psoriasis, Atopic Eczema
- Trial name
- NCT00555178
- Where
- 2 sites in Austria
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Stress, Anxiety
Effect of Light Level on Stress, Anxiety, Psychological Well-being in Pregnant Women
To determine the effect of light level on stress, anxiety and psychological well-being in pregnant women. This research was planned as a single-blind, randomized controlled experimental type study by comparing separate groups as…
- Conditions
- Stress, Anxiety, Pregnant Women
- Trial name
- NCT06504810
- Testing
- light
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Emine Yıldırım
Episiotomy Wound
Comparative Effects of Cryotherapy and Infrared Light on Pain, Redness, and Healing of Episiotomy Wound
The study will be a randomized clinical trial and will be conducted in Bahawalpur Victoria Hospital, Bahawalpur. The subjects (n=24) will be divided into two groups.
- Trial name
- NCT06325176
- Testing
- Cryotherapy, Infrared light therapy
- Where
- Pakistan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Mindfulness, Exercise
The Work Engagement and Wellbeing Study
Mindfulness and exercise are both widely used to improve mental health and well-being. Some people find that these activities also improve their ability to focus.
- Trial name
- SWELL (NCT04631302)
- Testing
- Be Mindful, Light exercise course
- Where
- United Kingdom
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Medical Research Council Cognition and Brain Sciences Unit
Veteran Aged 65 and Older
Promoting Cognitive Resilience and Reducing Frailty in Older Veterans With Bright Light Therapy
Frailty is a multifactorial syndrome characterized by vulnerability to stressors that is intricately linked to cognitive impairment and mortality risk.
- Trial name
- Brite-VET (NCT05631236)
- Testing
- Bright Light Therapy (AYO Glasses)
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Seasonal Affective Disorder
Influence of Light Exposure on Cerebral MAO-A in Seasonal Affective Disorder and Healthy Controls Measured by PET
This study aims to assess differences in monoamine oxidase A (MAO-A) distribution in the brain between seasonal affective disorder patients and healthy controls using positron emission tomography.
- Trial name
- NCT02582398
- Testing
- Light Therapy
- Where
- Austria
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Parent-Child Relations, Premature; Infant, Light-for-dates
The Effectiveness of Audiovisual Intervention
The objective of this clinical study is to understand the current status of parent-child bond, parenting role perception and well-being of fathers of preterm infants, and to explore the effect of audio-visual interventions on…
- Conditions
- Parent-Child Relations, Premature; Infant, Light-for-dates, Premature Infant Disease
- Trial name
- NCT06525142
- Testing
- Audiovisual Intervention
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Glaucoma, Open-Angle, Eye Diseases
The Flashing Light-Induced Pupil Response (FLIPR) Glaucoma Study
This study is designed to investigate whether the pupil response to slowly flashing colored lights is significantly altered in patients with glaucoma, as compared to a control group of subjects without glaucoma.
- Trial name
- FLIPR (NCT01857440)
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Quality of Life, Fatigue
Safety and Feasibility of Polychromatic Light Emitting Diode for Peripheral Catheter Illumination During Peripheral Intravenous Delivery of Normal Saline
This study uses a prospective non-randomized, non-controlled design. Five-hundred (500) subjects having previously received a peripheral intravenous therapy will be enrolled into a single treatment group.
- Trial name
- NCT02785133
- Testing
- UVL1000 Treatment Station, Normal Saline Solution, Peripheral Catheterization
- Where
- United States
- Volunteers
- 3,063 people, healthy volunteers welcome
- Sponsor
- UVLrx Therapeutics
Bright Light Treatment, Emotion
Effects of a Single Dose of Bright Light Treatment on Measures of Affective Information Processing
This study aims to investigate the effects of a single session of bright light treatment (BLT) on emotional information processing in healthy volunteers.
- Conditions
- Bright Light Treatment, Emotion, Facial Expression Recognition
- Trial name
- NCT03688048
- Testing
- Bright light treatment lamp
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Sedentary Behavior, Light Intensity Physical Activity
The Effect of Different Ways of Sitting on Cognitive Performance and Muscle Activity
Academic educations concurs with a lot of sitting. Studies have shown that prolonged sitting not only has disruptive effects on physical health, but also influence mental health and cognition negatively.
- Trial name
- NCT04716582
- Testing
- Sitting interrupted by light physical activity, Sitting with cognitive task, uninterrupted sitting
- Where
- Netherlands
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Myopia, Refractive Errors
PiXL as a Treatment for Low Grade Myopia
To assess the improvement in myopia with phototherapeutic intrastromal corneal collagen cross-linking (PiXL) without epithelial debridement (epi-on) in high oxygen environment for low grade myopia.
- Trial name
- NCT04663048
- Testing
- PiXL
- Where
- Sweden
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Umeå University
Hyperpigmentation
Pilot Study of LED for PIE and PIH
The aim of this study is to explore the effect of medical LEDs (830 nm and 590 nm) in the prevention and treatment of PIE and PIH.
- Trial name
- NCT06349447
- Testing
- LED, without any LED exposition
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Yanjun Dan
Cellulite
Phototherapy and Radiofrecuency for Cellulite
Cellulite is a condition that consists of an edematous infiltration of connective tissue. It has multiple factors in its etiology, making it difficult to choose just one type of treatment.
- Trial name
- NCT05441917
- Testing
- Sanae method with LED, Sanae method with Radiofrecuency
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Quiropraxia y Equilibrio
Pregnancy, Healthy Volunteers
Gastric Emptying During the Labour
Current recommendations permit the ingestion of all clear fluids (water, apple juice, black coffee..) during labour. However, regarding food during labour, the recommendations vary.
- Conditions
- Pregnancy, Healthy Volunteers, Parturition
- Trial name
- VGObstetric (NCT03490682)
- Testing
- Ultrasound assessment of gastric emptying of a flavoured yoghourt.
- Where
- France
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Rosacea, Papulopustular Rosacea
Photodynamic Therapy for Papulopustular Rosacea
Rosacea is a chronic inflammatory disorder that is characterized by severe flushing (transient erythema), non-transient erythema, papules, pustules, and telangiectasia.
- Trial name
- NCT02075671
- Testing
- Aminolevulinic acid topical solution 20%, Blu-U Light Therapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- George Washington University
Non-visual Photoreception
Investigating the Effects of Evening Light Exposure on Melatonin Suppression, Alertness and Nocturnal Sleep
The timing and quality of sleep is governed by environmental and physiologic factors. Environmental factors, especially ambient lighting can impact the circadian system and alter the timing and structure of sleep.
- Trial name
- NCT01586039
- Testing
- Visible light
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Pigment; Lesion, Lesion; Vascular
Image Data Collection of Tanned Skin During Phototherapy Treatment Using a Multi-spectral Camera
This is a prospective, observational, single-center, image collection study. Any patient who arrived at the phototherapy clinic for the first time, regardless of this study, and is prescribed a total of 30 treatments can be…
- Trial name
- NCT05692544
- Testing
- Phototherapy treatment
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Lumenis Be Ltd.
Light Exposure, Meal Timing
Role of Photic and Non-photic Time Cues in Resetting Circadian Rhythms
The aim of this study is to determine the principal time cue (light or meals) for resetting circadian rhythms in melatonin and metabolic outcomes.
- Trial name
- LipidPRC (NCT05276739)
- Testing
- Bright Light, Time-restricted eating, Dim light
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital