Clinical trials: Light
Daytime Cognitive Performance, Sleep
The Impact of Light Intensity in Home Workplaces on Remote Workers' Health
The lockdowns and restrictions associated with the COVID-19 have created a seismic shift in where work is done. Prior to the pandemic, approximately 20% of individuals were working from home while during the pandemic, more than…
- Conditions
- Daytime Cognitive Performance, Sleep, Alertness
- Trial name
- NCT05260801
- Testing
- Bright Lighting
- Volunteers
- healthy volunteers welcome
- Sponsor
- Arizona State University
Pain, Newborn
Developing a Portable Therapeutic Baby Nest for Newborns and Evaluation During Venous Blood Collection
The neonatal period covers the first 28 days after birth. Newborns may experience problems such as jaundice, restlessness, nasal congestion, respiratory distress, and vomiting in this process, and for these reasons, children are…
- Conditions
- Pain, Newborn, Comfort
- Trial name
- NCT05442619
- Testing
- Venous blood collection
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ankara University
Sedentary Lifestyle, Hyperinsulinemia
Developing a Physiological Understanding of High Duration Activity
When muscles are not contracting, the local energy demand by muscle and use of specific fuels used to produce energy by oxidative metabolism are minimal.
- Conditions
- Sedentary Lifestyle, Hyperinsulinemia, Glucose Tolerance Impaired, Low-density-lipoprotein-type
- Trial name
- NCT05135234
- Testing
- Muscular Exercise
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Houston
Sleep Disorder Circadian Rhythm, Delayed Sleep Phase Type
SleepHelsinki! CIRCADIAN SLEEP REGULATION IN ADOLESCENCE
Adolescence associates with alterations in sleep-wake organization, such as later circadian phase preference. Simultaneously external pressures, such as evening-driven social activities increase.
- Trial name
- SleepHel (NCT02964598)
- Testing
- Gamified intervention, Sleep coaching, Bright light
- Where
- Finland
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
General Anesthesia
Comparison of Conventional Lightwand Intubation Versus Video-laryngoscope Guided Lightwand Intubation in Simulated Cervical Spine-immobilized Patients
Among advanced intubation equipment for difficult intubation, a lighted stylet (lightwand) is a widely used equipment in cervical immobilized patients.
- Trial name
- NCT03169556
- Testing
- Video-laryngoscope guided lightwand, lightwand alone
- Where
- South Korea
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Procedural Pain, Neonatal Hyperbilirubinemia
The Effect of Kangaroo Care on Pain in Infants Receiving Phototherapy
This study aims to evaluate and compare the effects of two different kangaroo care (KC) models on pain management in neonates undergoing phototherapy.
- Trial name
- NCT07761689
- Testing
- Kangaroo Care, Routine Care
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Marmara University
Fetal Hypoxia
Trans-abdominal Fetal Pulse Oximetry; Tissue Light Scattering and Signal Integrity
The overall purpose of this study is to evaluate maternal-fetal tissue light scattering properties. The objectives of the study are: (i) integrate established mathematical principles of oxygen saturation to model with increasing…
- Trial name
- NCT04876846
- Testing
- GEN 3 Monitoring of Fetus
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Raydiant Oximetry, Inc.
COVID-19 Prevention
An Open Study on the Safety, Tolerability, and Immunogenicity of "Sputnik Light" Vaccine
Phase I-II open prospective, two-stage, non-randomized study in healthy volunteers.
- Trial name
- NCT04713488
- Testing
- Sputnik Light
- Where
- Russia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation
Colon Cancer
Narrow-Band Imaging Versus Standard White Light for the Detection of Serrated Lesions in the Proximal Colon
This is a study to determine if using Narrow-Band Imaging of the colon, rather than the usual white light on the colon, will improve the detection of a type of polyp called serrated.
- Trial name
- NCT01572428
- Testing
- Inspection with Narrow-Band Imaging(NBI), Standard White Light
- Where
- United States
- Volunteers
- 898 people, healthy volunteers welcome
- Sponsor
- Indiana University
Light Flashing Effects
Study of the Effects of Light Flashes on the Visual System
Background The goal of this study is to examine the human visual and cognitive performance under the effect of bright light pulses.
- Trial name
- NCT02629471
- Testing
- response time due to light flash pulses
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- LightGuard
Cranial Soft Tissue
Validation of a Method to Measure Soft Tissue Thickness Using Near Infrared Laser Light
The study is intended to verify a newly developed method to measure the thickness of cranial soft tissue. In the study, a high-resolution MRI scan is used as ground truth for a laser scan of the forehead.
- Trial name
- NCT01924338
- Testing
- MRI scan, Laser scan, Dental cast creation
- Where
- 2 sites in Germany
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Dr. Floris Ernst
Narrow Band Imaging
Comparison of ADR Using NBI Versus HD White Light Colonoscopy in Screening and Surveillance Colonoscopies
The aim of this study is to compare ADR using HD-NBI or HD-WLE during screening and surveillance colonoscopies.
- Trial name
- NCT03081975
- Testing
- HD white light or NBI
- Where
- Germany
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Jena University Hospital
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 4 of 7)
NOTE: This is the fourth of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02919228
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
Circadian Dysrhythmia, Delirium
The Circadian Rhythm of ICU Patients With Acute Myocardial Infraction and the Effect of Light Therapy
By using subjective and objective measurements, the investigators monitor the change of circadian rhythm in Intensive Care Unit (ICU) patients with acute myocardial infarction and the effect of light therapy.
- Trial name
- NCT04953767
- Testing
- Blue light therapy, White light
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Jaundice, Neonatal
Transcutaneous Bilirubin Measurements in Neonates Post Phototherapy
Can transcutaneous bilirubin (TcB) measurements be utilised to assess rebound hyperbilirubinaemia following phototherapy in neonates?
- Trial name
- NCT04719104
- Testing
- Transcutaneous Bilirubin Meter - 'Bilimeter'
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Pregnancy Related, Labor; Poor
Impact of Room Light on Uterine Contractions and Labor Progression in Pregnancy
Today it remains a challenge to successfully both halt and induce labor progression. Induction of labor is a common obstetric intervention that 1 in 4 women will experience.
- Conditions
- Pregnancy Related, Labor; Poor, Uterine Contractions Weak
- Trial name
- NCT04521972
- Testing
- Room light/light bulb
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Light Flashing
Effect of Different Color Lights on the Internal Clock and Alertness in Humans
The main aim of this study is to investigate the effects of cone-modulated light emitted from a visual display on human circadian physiology and cognitive performance in the evening.
- Trial name
- CONE (NCT05423002)
- Testing
- Flickering light stimuli, Constant light stimuli, Dim light
- Where
- Switzerland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Basel
Skin Neoplasms
Comparison of Two Modes of Photodynamic Therapy for the Treatment of Actinic Keratosis on the Upper Extremities
This study will be a prospective clinical trial performed in a single center, with 20 adult subjects presenting 4-17 clinically confirmed, mild to moderate AKs according to Olsen grading on each of two comparable treatment fields…
- Trial name
- NCT05359419
- Testing
- aminolevulinic acid hydrochloride gel, 10%, aminolevulinic acid HCl topical solution, 20%
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Breast Cancer Female
Identification of Benign and Malignant Breast Nodules Using Ultrasound-modulated Optical Tomography: A Multicenter Study
Ultrasonic light scattering imaging is a new functional imaging technology that combines traditional B-mode ultrasound imaging and light scattering tomography (DOT).
- Trial name
- NCT06468566
- Testing
- Ultrasound light scattering imaging equipment
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Xin-Wu Cui
Atopic Eczema
Narrowband Ultraviolet B Versus Narrowband Ultraviolet B Plus Ultraviolet A1 for Atopic Eczema
Narrowband ultraviolet B phototherapy is the "standard" phototherapy for atopic eczema; ultraviolet A1 is sometimes used but is not a widely available treatment.
- Trial name
- NCT02915146
- Testing
- combined ultraviolet phototherapy (NB-UVB + UVA1) vs. NB-UVB monotherapy
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Dundee