Clinical trials: Light
Long COVID, Distress Tolerance
Long COVID-19 Intervention Using Digital Health & Technology
The current study seeks to pilot test the iENDURE (Enhancing Distress tolerance to Uplift motivation in Recovery) intervention among 10 participants with Long COVID (Coronavirus Disease) symptoms.
- Trial name
- LIGHT (NCT05616806)
- Testing
- iENDURE
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Myopia, Ametropia
LED Low-Intensity Red Light for Myopia Control in Youth: Efficacy and Safety Study
The purpose of this clinical trial was to investigate the efficacy and safety of repetitive low-intensity single-wavelength red light from an LED light source in controlling myopia progression in children and adolescents.
- Trial name
- NCT07375589
- Testing
- Red light treatment with 1.6mW LED light source, Red light treatment with 0.001mW LED light source
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Alcohol Dependence, Insomnia
Pharmacotherapy and Mechanisms of Sleep Disturbance in Alcohol Dependence
Insomnia and other sleep abnormalities are common, persistent, and associated with relapse in alcohol-dependent patients. The overall, long-term objectives of the proposed research are to investigate the neurophysiologic…
- Trial name
- MA (NCT01014533)
- Testing
- Gabapentin dispensed to subject.
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Dr. Kirk Brower
Major Depression
The Effect of Exercise on Depressive Symptoms in Unmedicated Patients
This trial investigates the biological effect of exercise training on depression. Participants will randomly be allocated to either a aerobic exercise group performing exercise on stationary bikes or a group performing low-impact…
- Trial name
- DEMOII (NCT00695552)
- Testing
- Aerobic exercise, Low impact exercise
- Where
- Denmark
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Photoreceptor Sensitivity Thresholds
Wearable Dark-adaptometer in Normal Adult Healthy Volunteers
Conventional dark-adaptometers are unsuitable as a mass screening tool due to their high cost, lack of easy portability, need of trained staff and a totally dark room to be operated, arbitrary testing procedures, associated time…
- Trial name
- NCT02674425
- Testing
- Dark Adaptometer
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Corneal Diseases
Dynamic Light Scattering and Keratoscopy for Corneal Examination
This pilot study will examine the usefulness of a new instrument called the Dynamic Light Scattering (DLS) device for documenting and monitoring changes in the cornea, the front part of the eye where contact lenses are placed.
- Trial name
- NCT00050466
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Normal Healthy Eyes
Visual Performance With Spatial Light Modulator
Eye's aberrations have been known to degrade human visual performance and the visual performance is significantly improved when correcting the aberrations in the central visual field.
- Trial name
- NCT05134896
- Testing
- Spatial light modulator
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Houston
Shift Work Type Circadian Rhythm Sleep Disorder
The Effectiveness of Using Low-level Light Therapy to Treat Sleep and Psychological Symptoms Among Shift-work Nurses
The purpose of this study is to explore the treatment of Low Level Light Therapy(LLLT) mitigate possible insomnia and psychological symptoms, when nurses have taken shifts.The investigators hope that the goal of this…
- Trial name
- t-PBM (NCT05146596)
- Testing
- use low level light therapy,The Dr.Tai's energy cap
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Macula Edema, Retinal Vein Occlusion
Near-Infrared Light Photobiomodulation Treatment for Retinal Vein Occlusion Macular Oedema
This pilot study aims to establish that treatment with near infrared light (NIR) reduces cystic macular oedema in patients with a retinal vein occlusion.
- Trial name
- NIRVO (NCT04847869)
- Testing
- Ellex Integre NIR laser
- Where
- Australia
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Sydney
Algorithm Verification
mCVI® Lighting Conditions Clinical Study
This single center prospective clinical study is to verify the algorithm of mCVI® in 4 different lighting conditions to accurately capture pulse rate and respiratory rate in 10 healthy subjects in comparison to…
- Trial name
- NCT04811300
- Testing
- There is no intervention
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Intelomed, Inc.
Pigmentation
Evaluation of Broadband Light Treatment Protocol for Pigmented Skin Lesions - A Comparative Study
Evaluation of Broadband Light Treatment Protocols for Pigmented Skin Lesions - A comparative study
- Trial name
- NCT05662592
- Testing
- Broadband Light
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Sciton
Opioid; Intoxication, Perception Disturbance (Acute), Acute Pain
Pupillary Unrest in Ambient Light, and Relationship to Opioid-Induced Respiratory Depression
Volunteers will receive a weight-based opioid (remifentanil) infusion for 10 minutes. In the first run, serial pupillary measurements (pupillary unrest, pupil diameter) will be taken at baseline, and at 2.5-minute intervals…
- Conditions
- Opioid; Intoxication, Perception Disturbance (Acute), Acute Pain, Overdose of Opiate, Respiratory Depression
- Trial name
- NCT04301895
- Testing
- Continuous conversational interaction, Remifentanil infusion
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cardiovascular Disease
Conjugated Linoleic Acid Supplementation Study
Cardiovascular disease is a major cause of mortality worldwide resulting in one out of three global deaths. One of the main characteristics of cardiovascular disease is impaired blood flow and increased formation of clots.
- Trial name
- CLASS (NCT01234636)
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Sleep
Dose-dependent Impact of Daytime Lighting on Evening Responses to Light
The purpose of this study is to systematically examine the impact of different intensities of daytime light and the subsequent impact that such exposure has on non-image forming responses to light in the evening.
- Trial name
- NCT04882280
- Testing
- Light
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Palo Alto Veterans Institute for Research
Transthyretin Cardiac Amyloidosis, Light Chain Cardiac Amyloidosis
[18F]FIDT-10b PET Imaging in Cardiac Amyloidosis
This is a first in human study that will assess the safety, pharmacokinetics, biodistribution and diagnostic performance of [18F]FIDT-10b (fluorine-18 labeled FIDT-10b), a positron emission tomography (PET) agent.
- Trial name
- FIDTCA (NCT07835880)
- Testing
- [18F]FIDT-10b, 99mTc-PYP
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Light
Cardiometabolic Outcomes With Light Exposure During Sleep
This study tested the hypothesis that acute exposure to light during nighttime sleep adversely affects cardiometabolic function.
- Trial name
- NCT05317559
- Testing
- room light
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Dentin Sensitivity
Effect of Laser and Potassium Nitrate Application on the Sensitivity Control in Bleached Teeth
To investigate the effects of desensitizing agents on the dental bleaching process, testing the hypothesis that they may control dental sensitivity.
- Trial name
- NCT03434782
- Testing
- In-office dental bleaching, Low Level Laser Therapy, 5% potassium nitrate / 2% sodium fluoride gel
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Erythema
Characterisation of the Time-course Response of UV-induced Erythema
Erythema is a physiological response to an insult on the skin. One such insult is ultraviolet (UV) radiation, with the resultant erythema also known as sunburn.
- Trial name
- CHERY (NCT04290273)
- Testing
- MED Test, Wearing device
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Dundee
Keratoconus, Ectasia
Progressive Keratoconus or Ectasia Treatment Plan
Keratoconus and pellucid marginal degenerations are genetically based ocular conditions and post surgical ectasia is an iatrogenic condition.
- Trial name
- NCT01384773
- Testing
- Riboflavin Solution, UV-X Illumination System
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stephen Trokel
Major Depressive Disorder (MDD), Neuroimaging
Efficacy of Bright Light Therapy on Cognitive Impairment in Major Depressive Disorder and Its Neuroimaging Mechanisms: Protocol for a Randomised Controlled Trial
This study aims to validate the therapeutic efficacy and safety of bright light therapy (BLT) in ameliorating cognitive impairment (CI) in major depressive disorder (MDD), characterize the functional and structural features of…
- Conditions
- Major Depressive Disorder (MDD), Neuroimaging, Bright Light Treatment, Cognitive Impairment
- Trial name
- NCT07508215
- Testing
- BLT, DRL
- Where
- 2 sites in China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Peking University Sixth Hospital