Clinical trials: Light
Low-level Light Therapy, Cryotherapy
Comparison Between Low-level Laser Therapy, Intracanal Cryotherapy and Their Combination, on Post-endodontic Pain Level
Statement of the problem: Postoperative pain following endodontic treatment is a common complication that might require analgesics for pain relief.
- Trial name
- NCT04006717
- Testing
- Low Level Laser therapy, Intra canal Cryotherapy
- Where
- Egypt
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Misr International University
Circadian Rhythm Sleep Disorder, Delayed Sleep Phase, Sleep
The Effects of a Blue Monochromatic Light Intervention on Evening-type Individuals' Sleep and Circadian Rhythms
The present project is aimed to contribute with new knowledge concerning how light conditions in the physical environment can be manipulated to alter the sleep and circadian rhythms of individuals with an evening-type circadian…
- Trial name
- NCT03758768
- Testing
- Blue light exposure, Full spectrum light exposure
- Where
- Norway
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Bergen
White Spot Lesion of Tooth, Orthodontic Malocclusion
A Comparative Assessment of Orthodontic Treatment Outcomes Using the Quantitative Light-Induced Fluorescence Method
The aim of this 2-arm parallel trial was to evaluate enamel demineralization after an indirect bonding technique in comparison to a direct bonding technique group using the quantitative light-induced fluorescence method.
- Trial name
- QLF (NCT03738839)
- Testing
- Quantitative Light-Induced Fluorescence, Direct bonding, Indirect bonding
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Orthodontic Appliances, Low-Level Light Therapy
Photobiomodulation on Molar Verticalization With Mini-implant
The objective of this study will be to evaluate the effect of photobiomodulation on the acceleration of the orthodontic movement of molar verticalization and its effect on pain and inflammation of the periodontal tissues.
- Trial name
- NCT04036539
- Testing
- Placement of the mini-implant and verticalization
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Circadian Rhythm
Effects of Light and Exercise on Human Circadian Rhythms and Performance
Both light and exercise are effective countermeasures for space and ground-based crews for circadian phase resetting and alertness levels.
- Trial name
- NCT02747719
- Testing
- Light and exercise
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Fatigue in Multiple Sclerosis, Multiple Sclerosis
Fatigue in Multiple Sclerosis and Its Relationship to Inflammatory and Neurodegenerative Markers of the Disease
The study is focused on several independent quantifiable biomarkers (sNfL, sGFAP, mitochondrial activity, genetics and fatigue tests) to obtain more detailed information about MS and its progression.
- Conditions
- Fatigue in Multiple Sclerosis, Multiple Sclerosis, Neurofilaments Light Chains, GFAP
- Trial name
- MITOFATIGUE (NCT07025122)
- Where
- Slovakia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Martin
Cataract Extraction, Phacoemulsification
A Study Comparing Two Monofocal, Aspheric, Hydrophobic Acrylic Intraocular Lenses: the Alcon CLAREON® and the Abbott Medical Optics PCB00
This is a bilateral randomised controlled study to compare visual performance, refractive outcome, forward light scatter, patient satisfaction and objective measurement of glistenings following insertion of two monofocal…
- Conditions
- Cataract Extraction, Phacoemulsification, Glistenings, Intraocular Lens Implant
- Trial name
- NCT03364972
- Testing
- Cataract surgery
- Where
- United Kingdom
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Light Flashing Effects
Study of the Effects of Light Flashes on the Visual System
Background The goal of this study is to examine the human visual and cognitive performance under the effect of bright light pulses.
- Trial name
- NCT02629471
- Testing
- response time due to light flash pulses
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- LightGuard
Androgenetic Alopecia
Treatment of Androgenetic Alopecia in Males and Females
The purpose of this study is to evaluate the efficacy of Low Level Laser and Light Therapy system configured in a novel product called the TopHat 655 system, for promoting hair growth in males and females diagnosed with…
- Trial name
- LLLT (NCT01437163)
- Testing
- TopHat 655 rejuvenation system, Laser and/or Light Hair Rejuvenation System
- Where
- 4 sites in United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Apira Science, Inc.
Nicotine Dependence, Cigarettes
Evaluation of LLLT/Music for Smoking Cessation
The purpose of this research is to study the preliminary effectiveness of a light therapy and music device for at-home use to aid the seasoned cigarette smoker in his/her attempt to stop smoking.
- Trial name
- NCT04830384
- Testing
- Fully Active, LLLT Only, Music Only
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Freedom Laser, Inc.
Healthy
Study To Assess The Effect Of PF-04531083 On Heat Pain In Healthy Volunteers With Ultraviolet Light Sensitized Skin
PF-04531083 has been shown to reduce the amount of heat pain experienced by rats with skin that has been sensitized to heat by ultraviolet light. This study is designed to see if this is also true in man.
- Trial name
- NCT01127906
- Testing
- PF-04531083 100mg, PF-04531083 2000mg, Oxycodone 20mg
- Where
- Belgium
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Pfizer
Myopia
Effects of Blue of Glasses VS Standard Lenses on Contrast Sensitivity & Visual Fatigue in Myopic & Non-Myopic Adults
This study investigates the effects of blue light-blocking glasses compared to standard lenses on contrast sensitivity and visual fatigue in myopic and non-myopic adults.
- Trial name
- NCT06739525
- Testing
- Blue Light-Blocking Glasses (Intervention Group), Standard Lenses (Control Group)
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Superior University
Congenital Cataract
Digital Imaging Versus Ophthalmoscopy
Cataract (cloudiness of the lens) is the major cause of avoidable child blindness in the world and affects 1 in 3000 UK infants.
- Trial name
- DIvO (NCT05282147)
- Testing
- Neocam
- Volunteers
- 140,000 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Self Confidence
Pandemic and Gynecological Surgery Education
SarsCov2/COVID19 virus emerged in Wuhan, China in December 2019, and cases were seen in our country about 3 months later, causing a worldwide pandemic.
- Trial name
- NCT05143749
- Testing
- video tutorial
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
The Rate or Orthodontic Tooth Movement
The Effect of Light Emitting Diode Phototherapy on the Rate of Orthodontic Tooth Movement - A Clinical Study
LED Phototherapy will increase the velocity of Orthodontic tooth movement.
- Trial name
- NCT01490385
- Testing
- LED Phototherapy
- Where
- Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Bryan Tompson
Social Perception in Parkinson's Disease
Brain Mechanisms of Social Perception in Parkinson's Disease
Social cognition is a complex process that enables humans to interpret social information and behave appropriately in a social environment.
- Trial name
- Park Social (NCT06884722)
- Testing
- Behavioral task of social perception (stage 1), Functional magnetic resonance imaging: 3 Tesla magnetic resonance imaging (stage 2), Neurological and neuropsychological assessments
- Where
- France
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Mental Fatigue, Emergency Paramedics' Fatigue
The Reliability Assessment of Emergency Paramedics' Fatigue Using Automated Pupillometry
Due to the limitations of current approaches to assess emergency paramedics' fatigue, a portable, quick, easy, and objective technique is required to be developed.
- Trial name
- NCT04954430
- Testing
- pupillometer
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Sleep Deprivation, Circadian Rhythm
Circadian Rhythms and Time Perception in Healthy Adults During Constant Wakefulness
This study examines how the internal body clock (circadian rhythms) influences the way healthy adults experience time, think, and feel when they stay awake for an extended period.
- Conditions
- Sleep Deprivation, Circadian Rhythm, Healthy Volunteers, Time Perception
- Trial name
- CircaTime (NCT07294781)
- Testing
- Constant Routine Wakefulness
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
High Myopia, Axial Length
Repeated Low-Level Red-Light Therapy Shortens Axial Length
The purpose of this clinical trial is to investigate the incidence and magnitude of axial length shortening after repeated low-level red-light therapy in high myopia children and teenagers.
- Conditions
- High Myopia, Axial Length, Eye Diseases
- Trial name
- NCT05768152
- Testing
- RLRL
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Second People's Hospital of Foshan
Myopia, Refractive Error - Myopia
Minimum Power and Frequency of Repeated Low-level Red-light to Effectively Control Myopia Progression
To explore the minimum power and frequency of Repeated Low-level Red-light (RLRL) to control myopia progression in low-myopic children aged 8-10 years, and the rebound effect of low-myopic children after discontinuation of RLRL…
- Conditions
- Myopia, Refractive Error - Myopia, Choroidal Thickness, Retina
- Trial name
- NCT06717048
- Testing
- Repeated Low-level Red-light, Red LED
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center