Clinical trials: Light
Retinal Disease
Retinal Imaging With Oblique Illumination
Retinal diseases are the major cause of blindness in industrialized countries and while tremendous effort is made to develop novel therapeutic strategies to rescue retinal cells, optimal means to evaluate the effects of such…
- Trial name
- ASSESS (NCT04398394)
- Testing
- Cellularis version 1 imaging
- Where
- Switzerland
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Moser Christophe
Premature; Infant, Light-for-dates
Cue-based Tactile Stimulation and Infant Stress Reactivity
The present study is an examination of cue-directed tactile stimulation (CTDS), administered by mothers and NICU nurses, on infant and maternal stress reactivity, infant immune system functioning, maternal parenting cognitions…
- Trial name
- NCT01121523
- Testing
- Cue directed tactile stimulation
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Penn State University
Skin Inflammation, Acne
Joovvin' for Your Skin Health Study
Sixty day single arm trial examining self-report and remote dermatology assessment of cosmetic skin health after daily 10-20 minute sessions with an infrared light therapy device (the Joovv Mini)
- Conditions
- Skin Inflammation, Acne, Skin Diseases, Dermatological Non-Disease
- Trial name
- NCT04471896
- Testing
- Joovv Mini
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- ProofPilot
Elderly Men
Phototherapy in Association to Resistance Training in the Elderly: the Effect on Muscle Strength, Muscle Mass and Functional Capacity
Phototherapy has been largely used in rehabilitation programs due to its analgesic, antiinflammatory and healing effects. Lately, its effects of optimizing the results of resistance training on young individuals have been…
- Trial name
- NCT03287284
- Testing
- Active Low Level Laser Therapy, Resistance Training
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Health Science of Porto Alegre
Lung Cancer (NSCLC)
Snakehead Fish Extract and Curcumin Co-Supplementation in Advanced Lung Cancer on Inflammation, Nutritional Status, and Quality of Life
Background: Patients with advanced lung cancer receiving systemic therapy often experience nutritional decline, systemic inflammation, and impaired quality of life.
- Trial name
- BMI (NCT07906626)
- Testing
- Snakehead Fish Extract and Curcumin
- Where
- Indonesia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitas Sumatera Utara
Dental Caries
Validation of Near-infrared Light Transillumination for Interproximal Enamel Caries Detection
The aim of this study is to validate a near-infrared light transillumination device (DIAGNOcam, KaVo, Biberach, Germany) for interproximal enamel caries detection and compare it with the established diagnostic methods (visual…
- Trial name
- NCT02657538
- Testing
- Non invasive caries treatment, Invasive caries treatment, Near-infrared light transillumination device (DIAGNOcam, KaVo, Biberach, Germany)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Bern
Cellulite
Does Cell-U-Light Apparel Improve Cellulite
This trial is arranged in 3 stages, lasting 8 weeks overall, designed to assess the before, during and after effects of the low-compression apparel with its integrated, variably raised, ink-polymer pads.
- Trial name
- NCT05748678
- Testing
- Compression pants
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The Whiteley Clinic
Visible Light Exposures on Healthy Back Skin
Photoprotection Efficacy of a Sunscreen Under Visible Light Exposure by Using Two Different Simulators
To assess the ability of a protected agent to prevent the pigmentation under visible light exposures (VL) using two different simulators in healthy volunteers
- Trial name
- NCT06796140
- Testing
- Visible Light Exposure - Treated zone - Left hemi-back, Visible Light Exposure - Treated zone - Right hemi-back, Visible Light Exposure - Untreated zone - Left hemi-back
- Where
- Romania
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Disease Type and/or Category Not Applicable
Effectiveness of Light for Enhancement of Cognition by Transcranial Repeated Application (ELECTRA)
Aim: Investigate whether transcranial photobiomodulation (tPBM) using near-infrared light exposure to the head, can improve frontal lobe executive function, working memory and overall mood in normal volunteer participants.
- Trial name
- ELECTRA (NCT02817061)
- Testing
- Omnilux
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Hypoxia in Healthy Individuals
Hypoxia at Multiple Wavelengths of Light
The purpose of the study is to assess the effect of progressive, incremental hypoxia at multiple wavelengths of light.
- Trial name
- NCT01957891
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Nonin Medical, Inc
Physiological Adaptations, Sport Performance
Molecular Hydrogen Inhalation: Effects on Health, Exercise Capacity and Inflammatory Response - in Vivo/in Vitro Studies
Summary To comprehensively address the research aims and explore the state of knowledge of the mechanisms of biochemical response to specific tissue affecting method in form of a molecular hydrogen inhalation and will allow to…
- Conditions
- Physiological Adaptations, Sport Performance, Aerobic Capacity, Anaerobic Power
- Trial name
- NCT07130942
- Testing
- Inhalation using a molecular hydrogen generator
- Where
- Poland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Mild Cognitive Impairment, Cerebral Blood Flow
A Study of Low-level Light Therapy Using Photo-activated Modulation Ameliorates Cognitive Deficits
The primary objective of this study is to confirm and compare the effect of methods of Low-level light therapy (LED-T) in the mild cognitive impairment.
- Conditions
- Mild Cognitive Impairment, Cerebral Blood Flow, Low-level Light Therapy, Brain Activity
- Trial name
- NCT03192670
- Testing
- Low-level light therapy device
- Where
- 2 sites in South Korea
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Yong-il Shin, MD
Myopia
The Impact of Bright Classroom on Myopia
This trial aims to test the effectiveness and practicality of study in the Bright Classrooms with skylight and artificial light renovation in reducing incident myopia in Chinese primary school children over three years, as…
- Trial name
- IMPACT (NCT05156190)
- Testing
- bright classrooms with light level over 1000 lux
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Circadian Rhythm Sleep Disorder, Delayed Sleep Phase, Sleep
The Effects of a Blue Monochromatic Light Intervention on Evening-type Individuals' Sleep and Circadian Rhythms
The present project is aimed to contribute with new knowledge concerning how light conditions in the physical environment can be manipulated to alter the sleep and circadian rhythms of individuals with an evening-type circadian…
- Trial name
- NCT03758768
- Testing
- Blue light exposure, Full spectrum light exposure
- Where
- Norway
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Healthcare Associated Infection, Nosocomial Infection
Red Light Photobiomodulation and Topical Disinfectants
The goal of this clinical trial is to evaluate the potential effects of photobiomodulation when used with topical disinfectants in the anterior nares of healthy adults.
- Conditions
- Healthcare Associated Infection, Nosocomial Infection, Surgical Site Infection
- Trial name
- NCT05797818
- Testing
- Methylene Blue Only, Chlorhexidine Gluconate Only, Methylene Blue + Chlorhexidine Gluconate
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ondine Biomedical Inc.
Peripheral Artery Disease (PAD)
Using Near-Infrared Light to Better Understand Peripheral Artery Disease
The goal of this study is to better understand how blood flows and how oxygen is utilized in the lower limbs of people who suffer from peripheral artery disease.
- Trial name
- NCT07313410
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Breast Implants
Assessment of Safety & Efficacy of Light Weight Breast Implant
The purpose of this study is to evaluate safety and effectiveness of Light Weight Breast Implant (LWBI) in breast augmentation.
- Trial name
- NCT01874652
- Testing
- Light Weight Breast Implants
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Pigmentation
Safety and Efficacy of Broad Band Light In Motion Treatment
Evaluate safety and efficacy of Broad Band Light (BBL) motion technique treatment for pigmentation, skin tone and texture
- Trial name
- NCT03970317
- Testing
- Broad Band Light
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Sciton
Dental Deposits, Tooth Discoloration
Phototherapy Remediation of Black Stain
This study investigates the remediation of black-stained tooth surfaces using antimicrobial photodynamic therapy. In this crossover trial, a cohort of patients received standard dental prophylactic cleaning to remove the black…
- Conditions
- Dental Deposits, Tooth Discoloration, Dental Prophylaxis
- Trial name
- NCT03309748
- Testing
- Dental prophylaxis, Dental prophylaxis + antimicrobial photodynamic therapy
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Keratoconus
Accelerated Corneal Collagen Crosslinking Protocols
To evaluate and compare the effect of pulsed light (pl-ACXL) accelerated and continuous light accelerated (cl-ACXL) epithelium-off cross-linking in halting the progression of keratoconus.
- Trial name
- NCT05693740
- Testing
- Accelerated crosslinking (ACXL)
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Assiut University