Clinical trials: Light
Rapid Prototyping in Dentures
Complete Denture Tooth Movement in Digital Light Processing Versus Conventional Fabrication Techniques
The purposes of this study are to compare the denture tooth movement, the amount of occlusal adjustment needed and the chairside time required for CAD-CAM and conventional dentures.
- Trial name
- NCT04025697
- Testing
- Complete Denture, Rapid prototyped denture
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Cairo University
Shift-Work Related Sleep Disturbance, Sleep Deprivation
Light Intervention for Adaptation to Night Work
The project will contribute with new knowledge concerning how aspects of the physical work environment (lighting conditions) can be arranged to facilitate the workers' adaptation to night work.
- Conditions
- Shift-Work Related Sleep Disturbance, Sleep Deprivation, Sleep
- Trial name
- NCT03203538
- Testing
- LED-light, 1000 lux, LED-light, 100 lux, LED-light, 7000 K
- Where
- Norway
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Visual Snow Syndrome, Migraine
Investigating Brain Function in People With and Without Visual Snow Syndrome Using Adaptation to Visual Stimuli
The goal of this study is to learn more about the brain pathways and activity involved in creating Visual Snow Syndrome (VSS). The main questions it aims to answer are: Does VSS arise from spontaneous activity in brain pathways?…
- Conditions
- Visual Snow Syndrome, Migraine, Healthy
- Trial name
- VPVSS (NCT06961864)
- Testing
- Visual Adaptation, Assessments and Questionnaires, Functional Magnetic Resonance Imaging (fMRI)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Healthy Tissue, Muscles
Deep Optical Imaging of Tissue (DOIT)
In medical imaging, X-ray-based methods are widely used, which means that patients are exposed to ionizing radiation. In addition, invasive tissue samples often need to be taken with biopsy needles to, for example, safely…
- Conditions
- Healthy Tissue, Muscles, Extremity, Breast
- Trial name
- DOIT (NCT07754500)
- Testing
- Mk1
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lund University
Sedentary Lifestyle, Hyperinsulinemia
Developing a Physiological Understanding of High Duration Activity
When muscles are not contracting, the local energy demand by muscle and use of specific fuels used to produce energy by oxidative metabolism are minimal.
- Conditions
- Sedentary Lifestyle, Hyperinsulinemia, Glucose Tolerance Impaired, Low-density-lipoprotein-type
- Trial name
- NCT05135234
- Testing
- Muscular Exercise
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Houston
Photodamage
Single Band vs. Dual Band Pulsed Light Technology for the Treatment of Photodamage - A Split Face Comparison Study
Both the Dye - VL 500 - 600 nm and the Dual band will improve significantly the appearance of Photo Damage with high efficacy including; safety, minimal discomfort and downtime.
- Trial name
- NCT04519736
- Testing
- Single Band vs. Dual Band Pulsed Light Technology for the Treatment of Photodamage
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Alma Lasers Inc.
Depressive Disorder, Major
Clinical Efficacy, Safety, and Applicability of Home-based Bright Light Therapy in Outpatient Adolescents With Major Depressive Disorder
Major Depressive Disorder (MDD) is a chronic disease characterized by a high prevalence, low cure rate, and significant disability.
- Trial name
- NCT06913309
- Testing
- Bright light therapy（High light intensity）, Bright light therapy（Low light intensity）
- Where
- 3 sites in China
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Peking University Sixth Hospital
Presbyopia
The Light Sword Lens for Presbyopia Compensation
Clinical assessment of a new optical element for presbyopia compensation - the Light Sword Lens.
- Trial name
- NCT03716271
- Testing
- Visual Acuity Examination with a novel lens
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Military Institute od Medicine National Research Institute
Dental Caries, Dental Plaque
Orthodontic Varnish Microbiology Study
Orthodontic treatment is common in teenagers, which typically involve the attachment of metal brackets to the teeth. These brackets often impede proper oral hygiene, leading to plaque accumulation and the development of white…
- Conditions
- Dental Caries, Dental Plaque, Dental White Spot
- Trial name
- NCT04528134
- Testing
- Extended Contact RMGI (Resin-modified Glass Ionomer) Varnish, 5% Sodium Fluoride Varnish
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Sleep Initiation and Maintenance Disorders, Circadian Rhythm Sleep Disorders
Light Exposure to Treat Sleep Disruption in Older People
The purpose of this study is to test whether shifts in the timing of the biological clock to a later hour (phase delay shifts of the human circadian system) can be produced in response to four successive evenings of light…
- Conditions
- Sleep Initiation and Maintenance Disorders, Circadian Rhythm Sleep Disorders, Hypersomnia
- Trial name
- NCT00427323
- Testing
- light exposure
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Myopia, Refractive Errors
Light Emitting Diodes With a Continuous Spectrum of 430-780nm for Myopia Prevention
The purpose of this clinical trial is to evaluate the effect of light-emitting diodes (LEDs) with a continuous spectrum of 430-780 nm for lighting in the classroom on myopia prevention among children in Grades 2 and 3.
- Conditions
- Myopia, Refractive Errors, Eye Diseases
- Trial name
- NCT05728762
- Testing
- Novel LEDs
- Where
- China
- Volunteers
- 1,920 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Visual Fatigue, Dry Eye
A Study of Full-Spectrum Screen Lighting for Reducing Screen-Related Eye Fatigue and Dry Eye
This study will evaluate whether full-spectrum screen bar lighting can reduce eye fatigue and dry eye symptoms after a standardized screen task.
- Conditions
- Visual Fatigue, Dry Eye, Computer Vision Syndrome
- Trial name
- NCT07706231
- Testing
- Full-spectrum screen bar light, Brightness-matched screen task without screen bar lighting
- Where
- China
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Healthy
Evaluating Light-tissue Reaction and Transdermal Drug Delivery by Multiphoton Microscopy
In this study, the investigators will evaluate the potential of multiphoton microscopy as a non-invasive imaging modality for monitoring of the radiofrequency-tissue and light-tissue reaction.
- Trial name
- NCT01355328
- Testing
- laser and radiofrequency
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Athlete
Effects of Phototherapy by Light-emitting Diode Therapy (LEDT) on Clinical, Biochemical and Biomechanical of Muscle Performance in Athletes
Light-emitting diode Therapy (LEDT) has been used to improve human muscle performance in experimental models and human researches.
- Trial name
- NCT01770977
- Testing
- Light-emitting diode therapy
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Skeletal Muscle Hypertrophy, Muscle Weakness
The Effects of Lifting Light or Heavy Weights on Muscle Growth and Strength in Trained Young Men
When practicing weightlifting regularly the body makes new proteins within the muscle. These new proteins can increase the size of the cells within the muscle to make them larger, a process called hypertrophy.
- Trial name
- NCT02139865
- Testing
- 30% 1RM, 80% 1RM
- Where
- 2 sites in Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- McMaster University
Quality of Life, Fatigue
Safety and Feasibility of Polychromatic Light Emitting Diode for Peripheral Catheter Illumination During Peripheral Intravenous Delivery of Normal Saline
This study uses a prospective non-randomized, non-controlled design. Five-hundred (500) subjects having previously received a peripheral intravenous therapy will be enrolled into a single treatment group.
- Trial name
- NCT02785133
- Testing
- UVL1000 Treatment Station, Normal Saline Solution, Peripheral Catheterization
- Where
- United States
- Volunteers
- 3,063 people, healthy volunteers welcome
- Sponsor
- UVLrx Therapeutics
Colorectal Adenoma
Comparison of Detection and Miss Rates of Blue Laser Imaging Versus Conventional White Light Colonoscopy
It is a randomized controlled trial with tandem colonoscopy.Participants were randomized for use of either blue laser imaging or conventional White Light Colonoscopy on withdrawal method.comparison of detection and miss rates of…
- Trial name
- NCT02982447
- Testing
- blue laser imaging colonoscopy, conventional white light colonoscopy
- Where
- China
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Yangzhou No.1 People's Hospital
Healthy
Optimizing Phototesting and Investigating Photobiology of Visible Light
Specific Aim 1: To determine the impact of spectral composition of the VL+UVA1 source on the associated biologic effects. Specific Aim 2: To investigate differential responses of subjects with different skin phototypes to…
- Trial name
- NCT05964907
- Testing
- Light Source B: Visible Light solar simulator (VL + UVA1), Light Source A: Visible Light solar simulator closer match to sunlight (VL +UVA1)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Circadian Dysrhythmia, Delirium
The Circadian Rhythm of ICU Patients With Acute Myocardial Infraction and the Effect of Light Therapy
By using subjective and objective measurements, the investigators monitor the change of circadian rhythm in Intensive Care Unit (ICU) patients with acute myocardial infarction and the effect of light therapy.
- Trial name
- NCT04953767
- Testing
- Blue light therapy, White light
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Colon Adenoma
BLI, NBI or White Light Colonoscopy for Proximal Colonic Adenoma
This is a prospective randomised trial comparing the proximal adenoma detection rate and miss rate by blue laser imaging (BLI), narrow band imaging or white light colonoscopy.
- Trial name
- BNW (NCT03696992)
- Testing
- Tandem colonoscopy
- Where
- Hong Kong
- Volunteers
- 884 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong