Clinical trials: Light
Exposure to Man-made Visible Light
Peripheral Blood Flow Responses to Electromagnetic Energy
This study evaluates 670 nm energy in the form of red light to stimulate blood flow changes in healthy adults. All participants will receive red light to their leg.
- Trial name
- NCT02370199
- Testing
- 670 nm light, octafluropropane
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Bipolar Disorder, Light Sensitivity
Light at Night Study
The purpose of this mechanistic study is to examine light sensitivity (melatonin suppression) in people with bipolar depression I, and compare it to healthy controls. This is not a treatment study.
- Trial name
- LAN (NCT04251234)
- Testing
- Light intensity, ~30 lux, Baseline light intensity, <1 lux
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Muscle Development in Association to Phototherapy
Phototherapy Applied in Association With Strength Training
The effects of phototherapy has been widely studied by some research groups. The investigators know that there are positive results with light application to improve muscle performance and delay fatigue.
- Trial name
- NCT02474602
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Sun Damaged Skin
An Assessment of TLR4 and TOPK/PRPK Signaling in Sun Damaged Human Skin Acutely Exposed to Solar Simulated Light
The purpose of this project is to obtain clinical data, including skin samples, that will help investigators evaluate changes occurring in sun damaged human skin as a result of light that simulates sun exposure (Solar Simulated…
- Trial name
- NCT05398237
- Testing
- Solar Simulated Light (SSL)
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Progressive Keratoconus, Corneal Ectasia
Corneal Crosslinking in Keratoconus and Corneal Ectasia
Prospective, randomized, single site to determine the safety and effectiveness of performing corneal collagen cross-linking (CXL) using riboflavin and UVA light in eyes progressive keratoconus or corneal ectasia.
- Trial name
- CXL (NCT00679666)
- Testing
- Riboflavin
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ohio State University
Conditions for Lower Back Pain Working Nurse
LED Photobiomodulation Therapy for Non-specific LBP in Working Nurses
Background: Low back pain (LBP) affects approximately 51-57% of hospital nurses and nurses' aides in Europe. New high-risk groups include home- and long-term-care nurses and physiotherapists.
- Trial name
- NCT04424823
- Testing
- LED photobiomodulation
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital Hsin-Chu Branch
Normal Healthy Eyes
Visual Performance With Spatial Light Modulator
Eye's aberrations have been known to degrade human visual performance and the visual performance is significantly improved when correcting the aberrations in the central visual field.
- Trial name
- NCT05134896
- Testing
- Spatial light modulator
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Houston
Microleakage Around Resin Composite Restorations
Reliability of Light Induced Fluorescence Intraoral Camera Versus Visual-Tactile Method in Assessment of Marginal Integrity of Resin Composite Restorations: Diagnostic Invivo Study
This study will be conducted to assess diagnostic predictive values of a light induced fluorescence intraoral camera versus those of the visual-tactile assessment method according to FDI criteria in clinical evaluation the…
- Trial name
- NCT03090061
- Testing
- Light induced fluorescence intraoral camera, Visual-tactile assessment method according to FDI criteria
- Where
- Egypt
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Cairo University
Corneal Diseases
Dynamic Light Scattering and Keratoscopy for Corneal Examination
This pilot study will examine the usefulness of a new instrument called the Dynamic Light Scattering (DLS) device for documenting and monitoring changes in the cornea, the front part of the eye where contact lenses are placed.
- Trial name
- NCT00050466
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Acne Vulgaris
A Study to Evaluate the Potential of Tazarotene Foam to Cause an Allergic Reaction When Applied to the Skin and Exposed to Light on Healthy Volunteers.
The purpose of this study is to evaluate the potential of Tazarotene Foam to induce a photoallergic reaction when exposed to UV and VIS light on skin of healthy volunteers.
- Trial name
- NCT01119651
- Testing
- Tazarotene (Patch application in Challenge Phase)
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Stiefel, a GSK Company
Labor Pain and Anxiety, Labor Progress
Effects of Dim Light During Labor on Pain, Anxiety, and Labor Progress
The environment of the labor room may influence how women experience childbirth. Light levels, in particular, may affect comfort, stress, and the course of labor.
- Trial name
- DIM-LIGHT (NCT07310602)
- Testing
- Dim Light Exposure During Labor, Routine Labor Room Lighting
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Pınar Erdoğan
Photobiomodulation Therapy, Phototype
Light Reflection on Human Skin in Whole-Body Photobiomodulation Therapy
Photobiomodulation therapy (PBMT) is based on exposing biological tissues to low-intensity light, with effects depending on the light-tissue interaction.
- Trial name
- NCT06866522
- Testing
- Whole-body Photobiomodulation Therapy
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Pain
Effect of Green Light Exposure at Different Times on the Pain of Subjects
This study investigated the effects of green-light exposure on pain sensitivity in healthy volunteers and on perioperative pain in surgical patients.
- Trial name
- NCT07033949
- Testing
- Green light glasses
- Where
- China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Malocclusion Class I
Diode Laser Versus LED for Maxillary Canine Retraction in Orthodontic Patients
This study aims to compare the effects of diode laser and light-emitting diode (LED) photobiomodulation on maxillary canine retraction during fixed orthodontic treatment.
- Trial name
- NCT07810699
- Testing
- Diode Laser Photobiomodulation, LED Photobiomodulation
- Where
- Vietnam
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Can Tho University of Medicine and Pharmacy
Vestibular Disease
Helpfulness of the Vibration Test Performed in Room Light on Clients With Inner Ear Problems
The purpose of this study is to explore the diagnostic values associated with both a positive and negative Skull Vibration Induced Nystagmus Test (SVINT) performed in room light (with fixation). The hypotheses include: 1.
- Trial name
- NCT02626052
- Testing
- Dizziness Handicap Inventory, Global Rating of Change, Patient Acceptable Symptom State
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Aultman Health Foundation
Overweight, Obesity Grade I
Light, Exercise Intensity and Mood in Overweight
The purpose of this study is to determine if an exposure to light in the morning has a positive influence on self-chosen exercise intensity on a bicycle ergometer in overweight and obese patients.
- Trial name
- LEXI-MO (NCT02636335)
- Testing
- Phillips Energy Light HF3319
- Where
- Switzerland
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Basel
Cognitive Performance, Sleep
Evaluating the Potentials of Biodynamic Lighting for Home Office Workers
This study examines the effectiveness of a biodynamic lighting intervention on the sleep, cognitive functions, and alertness of adults working from home.
- Conditions
- Cognitive Performance, Sleep, Alertness
- Trial name
- NCT05481424
- Testing
- Biodynamic
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Plaque Psoriasis
A Study to Assess Patient-Reported Wellbeing Using Tildrakizumab in a Live Setting
The main purpose of this study to investigate the relationship between clinical symptoms and quality of life (QoL) in participants who receive Tildrakizumab in the frame of clinical routine for the treatment of moderate to severe…
- Trial name
- NCT06488170
- Testing
- Tildrakizumab
- Where
- 7 sites in Czechia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Almirall, S.A.
Visible Light Exposure, Healthy Back Skin
Photoprotection Efficacy of Four Sunscreen Formulas Under Visible Light Exposure
To evaluate the protective effect of four sunscreens on the pigmentation caused by visible light in comparison to an untreated control zone in healthy volunteers.
- Trial name
- NCT06796010
- Testing
- Visible Light Exposure - Treated zones, Visible Light Exposure - Untreated zone
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Relapse Remitting Multiple Sclerosis
Early Versus Delayed Start of Ocrevus Zunovo for Relapsing Multiple Sclerosis
This study will compare starting Ocrevus Zunovo soon after an active episode of relapsing multiple sclerosis (MS) with starting it later.
- Trial name
- STAT (NCT07878923)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Oklahoma Medical Research Foundation