Clinical trials: Light
Age Related Macular Degeneration
Association of MPOD Values With Blue Light.
This study aims to investigate in healthy adults 18-65 years of age the association of electronic device blue light exposure and macular pigment optical density (MPOD) considering usual dietary intake of lutein and zeaxanthin…
- Trial name
- AMPBL19 (NCT04779398)
- Where
- Australia
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
Androgenetic Alopecia
Treatment of Androgenetic Alopecia in Males and Females
The purpose of this study is to evaluate the efficacy of Low Level Laser and Light Therapy system configured in a novel product called the TopHat 655 system, for promoting hair growth in males and females diagnosed with…
- Trial name
- LLLT (NCT01437163)
- Testing
- TopHat 655 rejuvenation system, Laser and/or Light Hair Rejuvenation System
- Where
- 4 sites in United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Apira Science, Inc.
Pigmentation
The Effect of Topical Sunscreen Plus Antioxidant Against the Visible Light Biological Effects
Visible light is known to induce pigmentation in darker skin types. The investigators aim to study the effects of visible light on the skin after topical application of sunscreen plus antioxidant.
- Trial name
- NCT03065582
- Testing
- Topical Product A, Topical Product B, Topical Product C
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Systemic Light Chain Amyloidosis, Ocular Complications
The Impact of Systemic Light Chain Amyloidosis on Eyes
Study Purpose and Principle: Amyloidosis is a group of diseases characterized by the deposition of amyloid proteins in tissues and organs throughout the body, with common affected organs including kidneys, heart, nervous system…
- Trial name
- Amyloidosis (NCT06803082)
- Where
- China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Gastric Cancer, Preneoplastic Condition
BLI for the Diagnosis of Precancerous Conditions
Introduction: Traditionally, White Light Endoscopy (WLE), enhanced by biopsies following the updated Sydney system guidelines, has been the benchmark for diagnosing and classifying gastric preneoplastic conditions.
- Conditions
- Gastric Cancer, Preneoplastic Condition, Early Gastric Cancer
- Trial name
- NCT04768218
- Where
- Portugal
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Instituto Portugues de Oncologia, Francisco Gentil, Porto
Pre-frontal Cortical Oxygenated and Deoxygenated Hemoglobin Levels
Effects of Light Intensity Physical Activities on Pre-frontal Cortical Activation, Cognitive Function, Sleepiness and Back Pain
The objective of this randomised controlled trial is to examine the acute effects of two novel light intensity exercise (sit-cycling and stand-twisting) on prefrontal cortical blood oxygenation, executive functioning, sleepiness…
- Trial name
- NCT06703424
- Testing
- Sit-cycling, Stand-twisting
- Where
- Singapore
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Chia Yong Hwa Michael
Jaundice, Neonatal
Treatment of Neonatal Jaundice With Filtered Sunlight Phototherapy: Safety and Efficacy in African Neonates
The primary objective of this study is to determine the safety and efficacy of filtered sunlight phototherapy. Sunlight will be filtered by flexible (window-tinting) film.
- Trial name
- NCT01434810
- Testing
- Filtered-sunlight phototherapy, Conventional phototherapy
- Where
- Nigeria
- Volunteers
- 447 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Healthy Lifestyle, Adolescent Behavior
Living Green and Healthy for Teens
This is a two-group parallel randomized controlled trial testing whether a gamified healthy living smartphone app for youth aged 10-16 representative of the Canadian population and one of their parents is more effective at…
- Trial name
- LiGHT (NCT03996109)
- Testing
- Aim2Be smartphone app system, BnLt smartphone app
- Where
- Canada
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Population Health Research Institute
Polymorphic Light Eruption
Protective Effect Assessment of Foto Ultra Isdin Solar Allergy Fusion Fluid on the UVA Induced PLE
The primary objective of this Clinical Investigation was to assess the protective efficacy of a medical device (FOTO ULTRA ISDIN® SOLAR ALLERGY FUSION FLUID) against the polymorphic light eruption induced by the UVA.
- Trial name
- NCT05320315
- Testing
- Foto Ultra ISDIN® Solar Allergy Fusion Fluid
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Centre de Pharmacologie Clinique Applique a la Dermatologie
Sleep
Energy-efficient and Health Promoting Light for Elderly People
to investigate the effect of two lightning conditions on sleep hypothesizing that sleep length is influenced by the color of light during daytime
- Trial name
- light-age (NCT02216318)
- Testing
- blue light
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
Amyloidosis; Systemic, Amyloidosis Cardiac
Essen Amyloidosis Registry
The Essen Amyloidosis Registry (EAR) is a prospective, observational registry designed to collect comprehensive clinical data on patients diagnosed with systemic amyloidosis.
- Trial name
- EAR (NCT06887283)
- Where
- Germany
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Hospital, Essen
Healthy
UVB: Skin to Gut Study
This research will explore the potential effects of Narrow-Band Ultra Violet B (NB-UVB) radiation on the intestinal microbiota composition and confirm a regulatory skin-to-gut axis during baseline conditions.
- Trial name
- NCT03962673
- Testing
- NB-UVB light exposure
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Helicobacter Pylori Infection
White Light Endoscopy and Magnifying Endoscopy in Assessing the Status of Hp Infection
By comparing the characteristics of Helicobacter pylori (Hp) infection under magnifying endoscopy and white light endoscopy, and making judgments of Hp infection status, the advantages and disadvantages of the two endoscopic…
- Trial name
- NCT06397066
- Testing
- White light endoscopy group, Magnifying endoscopy group
- Where
- China
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Jilin University
Sleep Disorders, Circadian Rhythm
Effectiveness of Combining Light and Non-Light Treatments for Jet Lag and Sleep Disorders
Jet lag and some sleep disorders are caused by a disruption in an individual's "internal clock." Understanding the most effective way to quickly re-adjust the body's internal clock will be beneficial for treating individuals with…
- Trial name
- NCT00387179
- Testing
- Melatonin, Methylxanthine, Light Therapy
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Healthy, Teenager
Effects of Afternoon and Evening Light on Teenagers' Melatonin Levels, Alertness, Sleepiness and Sleep
Many teenagers are familiar with this: on school days, they have to get up early; during the day, they hardly get any light exposure; in the evening, they go to bed late - and are then tired at school the next day! Around the…
- Conditions
- Healthy, Teenager, Healthy Lifestyle
- Trial name
- TeenLight (NCT05483296)
- Testing
- Dim light condition, Moderate light condition, Bright light condition
- Where
- Switzerland
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University Psychiatric Clinics Basel
Post Concussive Symptoms
Chasing Biomarkers in Post-concussion Syndrome
The goal of this study was to investigate the biomarkers, neurofilament light chain, inflammatory markers, calcitonin-gene-related peptide, and metabolites from the kynurenine pathway in patients with severe post-concussive…
- Trial name
- NCT05812742
- Testing
- Early intervention programme, Enhanced usual care
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Dental Caries, Endodontically Treated Teeth
Clinical Evaluation of Posterior Indirect Adhesive Restorations
Clinical performance of indirect adhesive restorations - onlays, overlays- luted with light-cured composite resin will be evaluated over three years.
- Conditions
- Dental Caries, Endodontically Treated Teeth, Dental Restoration Failure of Marginal Integrity, Wear, Occlusal
- Trial name
- NCT04293770
- Testing
- Indirect adhesive restoration of posterior teeth
- Where
- Turkey (Türkiye)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Okan University
General Anesthetics Toxicity
Anesthetic Neurotoxicity: the Association Between General Anesthesia and the Level of Plasma Neurofilament Light
A prospective controlled single centre study designed to determine the association between the exposure to anesthetic agents and the pre and postoperative changes in plasma Neurofilament Light levels, biomarkers of neurological…
- Trial name
- ANESTOX-2019 (NCT04164329)
- Testing
- General anesthetic
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cardiocentro Ticino
Wound Heal, Vestibular Abnormality
Comparison of Diode Laser-Assisted Vestibuloplasty And Conventional Vestibuloplasty
Randomized controlled parallel designed clinical study aimed to compare vestibule depth gain and dimensional changes of wound area in individuals who underwent vestibule deepening surgery using diode laser and conventional…
- Conditions
- Wound Heal, Vestibular Abnormality, Low-level Light Therapy, Surgical Wound
- Trial name
- NCT05252260
- Testing
- Diode Laser, Conventional Surgery, Low level laser therapy (LLLT)
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Sleep
Phase II Study - Trial of a Phototherapy Light Device to Improve Sleep Health
There are few devices currently on the market claiming to improve sleep. This study will investigate the efficacy of phototherapy on improving sleep, in the form of a wearable neck device used at night.
- Trial name
- PHOTONS (NCT05116358)
- Testing
- Phototherapy device
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Arizona