Clinical trials: Light Therapy
Gastro-Intestinal Disorder
Minimal Risk Registry of Endoscopic Image and Pathology Correlation for Fujiflim
The purpose of this study is to see if advanced endoscopic imaging may be helpful to accurately distinguish pathological tissue from normal tissue and guide therapy of endoscopically identified pathology.
- Trial name
- NCT03440047
- Testing
- Fuji Flim Processor VP-7000, Light Source BL-7000
- Where
- 2 sites in United States
- Volunteers
- 355 people
- Sponsor
- Mayo Clinic
Amyloidosis
A Dose Escalation Study of Carfilzomib Taken With Thalidomide and Dexamethasone in Relapsed AL Amyloidosis
This study evaluates the safety and efficacy of carfilzomib used in combination with thalidomide and dexamethasone in patients with relapsed AL amyloidosis.
- Trial name
- CATALYST (NCT02545907)
- Testing
- Carfilzomib, Thalidomide, Dexamethasone
- Where
- 14 sites in United Kingdom
- Volunteers
- 10 people
- Sponsor
- University College, London
Sun Sensitivity
Deliberate Ultraviolet Light Exposure to Get a Tan by Young Adult Sexual Minority Males
The purpose of this study is to: a) identify enablers and barriers to deliberate ultraviolet light exposure by young sexual minority men (SMM), and b) quantify the extent of their deliberate ultraviolet light exposure.
- Trial name
- NCT04404907
- Testing
- no intervention
- Where
- United States
- Volunteers
- 537 people
- Sponsor
- Northwestern University
Dry Eyes Chronic
Intense Pulsed Light Study for Dry Eye Disease
This study will evaluate the efficacy of intense pulsed light (IPL) therapy for the treatment of dry eye disease. One eye of the participant will be randomized to receive the IPL treatment.
- Trial name
- NCT03089580
- Testing
- Intense Pulsed Light Therapy
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Michigan
Bladder Cancer
Effectiveness of Hexaminolevulinate (Hexvix) in the Diagnosis and Treatment of Patients With Non-invasive Bladder Cancer
The purpose of this study is to determine the effectiveness of hexaminolevulinate (Hexvix) in the diagnosis and treatment of patients with non-invasive bladder cancer and if it results in a change in patient management.
- Trial name
- NCT00634621
- Testing
- Hexaminolevulinate (Hexvix)
- Where
- Spain
- Volunteers
- 283 people
- Sponsor
- GE Healthcare
AL Amyloidosis
Open-label Extension Study of NEOD001 in Subjects With Light Chain (AL) Amyloidosis
The rationale for this study is to provide additional treatment with NEOD001 for subjects who complete Study NEOD001-001, and to continue to evaluate long term safety and tolerability.
- Trial name
- OLE (NCT02613182)
- Testing
- NEOD001
- Where
- 5 sites in United States
- Volunteers
- 34 people
- Sponsor
- Prothena Biosciences Ltd.
Hypertrichosis
Pilot Study of a Novel IPL for Removal of Unwanted Fine Body Hair
The purpose of this randomized, controlled, open-label pilot study is to evaluate the safety and efficacy of a novel intense pulsed light (IPL) device for removal of unwanted fine body hair.
- Trial name
- NCT01912950
- Testing
- Prowave LX IPL
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Bipolar Disorder, Major Depressive Episode
Light Therapy for Bipolar Disorder. Efficacy of Light Therapy for Bipolar Depression: A Randomized Controlled Trial
The purpose of this study is to understand the efficacy of light therapy for bipolar depression.
- Trial name
- NCT00852592
- Testing
- 7000lux broad-spectrum light, 50lux dim red light
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- Northwestern University
Gulf War Veterans Illness, Neurobehavioral Manifestations
Scalp Application of LED Therapy to Improve Thinking and Memory in Veterans With Gulf War Illness
The purpose of this study is to learn if an experimental treatment can help thinking ability, and memory in Veterans with Gulf War Veterans Illnesses (GWVI).
- Conditions
- Gulf War Veterans Illness, Neurobehavioral Manifestations, Memory Disorders
- Trial name
- NCT01782378
- Testing
- Real LED Treatment
- Where
- 2 sites in United States
- Volunteers
- 96 people
- Sponsor
- VA Office of Research and Development
Vitamin D Deficiency, Vitamin D Insufficiency
Evaluating the Effect of SOLIUS UV Light Source in Improving Vitamin D Status
The aim of this study is to evaluate the safety and effectiveness of the SOLIUS System in improving serum levels of 25-hydroxyvitamin D in vitamin D deficient/ insufficient adults of various skin types.
- Trial name
- NCT04780776
- Testing
- UVB treatment
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Boston University
Autistic Disorder
An Evaluation of Low Level Laser Light Therapy for Autistic Disorder
The purpose of this study is to determine whether the Erchonia HLS Laser is effective in the treatment of irritability associated with autistic disorder in children and adolescents aged five (5) to seventeen (17) years.
- Trial name
- NCT03379662
- Testing
- Erchonia HLS Laser
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Erchonia Corporation
Delayed Sleep Phase Syndrome
Randomized Controlled Trial on the Treatment Effects of Melatonin and Light Therapy on Delayed Sleep Phase Syndrome
In this study the investigators will examine the effects of melatonin and light therapy on delayed sleep phase syndrome in adolescents 16 up to 20 years old.
- Trial name
- NCT00834886
- Testing
- Melatonin, Bright light
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- University of Bergen
Primary Systemic Amyloidosis
Doxycycline to Upgrade Organ Response in Light Chain (AL) Amyloidosis Trial
In this study the investigators want to find out more about the addition of the antibiotic, doxycycline, to standard anti-amyloid therapy in people with amyloidosis.
- Trial name
- DUAL (NCT02207556)
- Testing
- Doxycycline
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Medical College of Wisconsin
Venous Stasis Ulcer
Efficacy Study of the Application of Low Level Laser Light to Treat Venous Stasis Ulcers
The purpose of this study is to determine whether low level laser light therapy is effective as an adjunctive therapy to the healing of venous stasis leg ulcers.
- Trial name
- NCT01376050
- Testing
- Erchonia ML Scanner (MLS)
- Where
- 2 sites in United States, France
- Volunteers
- 24 people
- Sponsor
- Erchonia Corporation
Prostate Cancer, Bladder Cancer
Project HERO: Health Empowerment & Recovery Outcomes
Project HERO is a 12-week study of the efficacy of Body Mind Training (BMT, i.e. Tai Chi and Qigong in this project) for reducing fatigue in male cancer survivors.
- Conditions
- Prostate Cancer, Bladder Cancer, Kidney Cancer, Colon Cancer
- Trial name
- HERO (NCT03345563)
- Testing
- Body Mind Training (BMT), Body Training (BT):, Usual Care (UC)
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Rutgers, The State University of New Jersey
Hypertension, Prehypertension
Effect of Reducing Sedentary Behavior on Blood Pressure
This is a 2-arm, 3-month randomized trial comparing a novel sedentary behavior intervention vs. control in working adults (n=271).
- Trial name
- RESET-BP (NCT03307343)
- Testing
- Intervention
- Where
- United States
- Volunteers
- 271 people
- Sponsor
- University of Pittsburgh
Autism, Attention Deficit Hyperactivity Disorder
Transcranial Photobiomodulation Therapy for the Treatment of Autistic Traits in Children and Adolescents With ADHD
An open label trial to assess the safety and efficacy of transcranial photobiomodulation (tPBM) in improving autistic traits in ADHD youth.
- Trial name
- NCT04569058
- Testing
- Transcranial Photobiomodulation
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Massachusetts General Hospital
AL Amyloidosis
A Study to Evaluate the Efficacy and Safety of CAEL-101 in Patients With Mayo Stage IIIa AL Amyloidosis (CARES)
AL (or light chain) amyloidosis begins in the bone marrow where abnormal proteins misfold and create free light chains that cannot be broken down.
- Trial name
- NCT04512235
- Testing
- CAEL-101, cyclophosphamide, bortezomib, and dexamethasone (CyBorD) regimen
- Where
- 110 sites in United States, Australia and 17 more
- Volunteers
- 281 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Diabetic Macular Oedema
Near Infrared Photobiomodulation Treatment for Diabetic Macular Oedema
This pilot study aims to establish that treatment with near infrared light (NIR) reduces diabetic macular oedema in patients suffering diabetic retinopathy by exerting a positive beneficial effect at retinal cellular level.
- Trial name
- NIRD (NCT02181400)
- Testing
- Ellex Integre NIR laser
- Where
- Australia
- Volunteers
- 21 people
- Sponsor
- University of Sydney
Keratosis, Actinic
Levulan PDT Versus Vehicle for Extremity Actinic Keratoses (AK)
The purpose of this study is to determine if Levulan PDT is safe and effective in the treatment of actinic keratoses on the upper arms and hands.
- Trial name
- NCT01458587
- Testing
- Aminolevulinic Acid PDT (ALA), Vehicle PDT (VEH)
- Where
- 3 sites in United States
- Volunteers
- 70 people
- Sponsor
- DUSA Pharmaceuticals, Inc.