Clinical trials: Light Therapy
Lung Adenocarcinoma, Lung Adenosquamous Carcinoma
Erlotinib Hydrochloride With or Without Carboplatin and Paclitaxel in Treating Patients With Stage III-IV Non-small Cell Lung Cancer
This randomized phase II trial studies how well erlotinib hydrochloride with or without carboplatin and paclitaxel works in treating patients with stage III-IV non-small cell lung cancer.
- Conditions
- Lung Adenocarcinoma, Lung Adenosquamous Carcinoma, Malignant Pericardial Effusion, Malignant Pleural Effusion
- Trial name
- NCT00126581
- Testing
- Carboplatin, Erlotinib, Erlotinib Hydrochloride
- Where
- 96 sites in United States
- Volunteers
- 188 people
- Sponsor
- National Cancer Institute (NCI)
Alzheimer's Disease, Mild Cognitive Impairment
Investigating the Impact of Duration and Amount of Light on the Circadian System Response - Aim 3
Investigate the long-term impact of amount and duration of Tailored Lighting Intervention (TLI) obtained from Aims 1 and 2 on sleep, cognition, circadian marker, mood, and behavior in AD/ADRD patients.
- Trial name
- NCT06595030
- Testing
- Active Lighting Intervention, Control Lighting Intervention
- Where
- 2 sites in United States
- Volunteers
- 101 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Dry Eye Disease (DED), Meibomian Gland Dysfunction
Treatment Effect of Intense Pulsed Light and Thermal Pulsation Therapy on Meibomian Gland Dysfunction-associated Dry Eye Disease: a Randomized Trial
The goal of this clinical trial is to understand novel treatment methods for meibomian gland dysfunction (MGD)-associated dry eye disease (DED) by comparing two treatment modalities- intense pulsed light (IPL) and thermal…
- Trial name
- NCT06745089
- Testing
- Intense pulsed light, thermal pulsation therapy, Ocular lubricant
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- National Yang Ming Chiao Tung University
Chronic Periodontitis, Diabetes Mellitus
Low-level Laser Therapy in the Treatment of Chronic Periodontitis in Type 2 Diabetics
The aim of this study was to investigate the local effect of adjunct low-level laser therapy (LLLT) for the treatment of moderate to severe chronic periodontitis in type 2 diabetic patients.
- Trial name
- NCT02817152
- Testing
- Periodontal ultrasonic debridement, Debridement plus low-level laser therapy
- Volunteers
- 20 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Amyloid Light-chain Amyloidosis
Daratumumab/Daratumumab and Hyaluronidase-fihj in Combination With Pomalidomide and Dexamethasone for the Treatment of Patients With Newly Diagnosed AL Amyloidosis: a Prospective, Multicenter, Single-arm Study
This is a prospective and single arm clinical study. The goal of this clinical trial is to observe and evaluate the efficacy and safety of Daratumumab/daratumumab and hyaluronidase-fihj in combination with pomalidomide and…
- Trial name
- NCT06455748
- Testing
- Daratumumab/daratumumab and hyaluronidase-fihj, Pomalidomide, Dexamethasone
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Yongyong MA
Light Sensitivity
Eye Movement Behaviour and Pupil Size in Natural Outdoor and Indoor Scenes
In this study, the researchers will be using eye tracking and detailed lighting measurements to understand how different types of indoor and outdoor lighting affect the eye movements and pupil sizes of our participants.
- Trial name
- NCT05971238
- Testing
- Indoor vs. outdoor scenes
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Rosacea
Efficacy of IPL, an Anti-redness Dermocosmetic, and Their Combination in the Treatment of Rosacea
This study compares three approaches to treating persistent facial redness in adults with erythematotelangiectatic rosacea: intense pulsed light (IPL) treatment alone, a professional anti-redness dermocosmetic skincare regimen…
- Trial name
- NCT07729540
- Testing
- Intense Pulsed Light (IPL) - Lumecca, Rosacure anti-redness dermocosmetic regimen
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Silesia
Polymorphic Light Eruption
Skin Microbiome and Polymorphic Light Eruption
Polymorphic light eruption (PLE) is the most common form among UV-inducible disorders with a prevalence of approximately 11-21% worldwide and a clear predisposition of women.
- Trial name
- PLE_microbio (NCT04985526)
- Testing
- Octeniderm (octenidine dihydrochloride, 1-propanol, 2- propanol)
- Where
- Austria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Breast Cancer, Genitourinary Syndrome of Menopause
Sexual and Vaginal Health in Breast Cancer Women Receiving Aromatase Inhibitors Before and After CO2 Laser Therapy
Background: Vulvovaginal health, directly linked to sexual health, is a key factor for female pleasure. BCS receiving AI are likely to present severe GSM and sexual complaints.
- Trial name
- LIGHT (NCT04619485)
- Testing
- CO2 LASER
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- Hospital Clinic of Barcelona
Fine Lines, Contour
Evaluation of the Efficacy of a Cosmetic Light Mask
The present study evaluated facial skin health over a 12-week period using an at-home device that provides 12 minutes of LED light and vibration once daily, six days a week.
- Conditions
- Fine Lines, Contour, Sagging Skin, Dark Spots
- Trial name
- NCT07054710
- Testing
- LED Light Treatment, Vibration Only
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- Therabody, Inc.
Parkinson Disease
Assessment of Pupil Light Responses in Patients With Parkinson Disease
Parkinson diseases (PD) is the second most common degenerative disease of the central nervous system. The development of early diagnostic biomarkers may help identify at-risk individuals and allow precocious interventions at the…
- Trial name
- NCT04117555
- Testing
- Pupil response to light stimuli
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Sheba Medical Center
Dry Eye Disease (DED)
Photobiomodulation in Combination With Topical Cyclosporine A or Tacrolimus
The objective of the study is to evaluate the effectiveness of Low-level light therapy (LLLT) in combination with either topical Cyclosporine A (CsA) or topical Tacrolimus, using each non-steroidal immunosuppressant as an active…
- Trial name
- NCT07239128
- Testing
- Low-level light therapy (LLLT), Topical Cyclosporine A, Topical tacrolimus
- Where
- 2 sites in Italy
- Volunteers
- 160 people
- Sponsor
- University of Seville
Bipolar Disorder, Light Sensitivity
Light at Night Study
The purpose of this mechanistic study is to examine light sensitivity (melatonin suppression) in people with bipolar depression I, and compare it to healthy controls. This is not a treatment study.
- Trial name
- LAN (NCT04251234)
- Testing
- Light intensity, ~30 lux, Baseline light intensity, <1 lux
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Colorectal Neoplasms, Colonic Polyps
Study of Flat Polyp Detection Using New Narrow Band Imaging (NBI) Compared to White Light Colonoscopy - The FIND FLAT Colonoscopy Study
We hypothesize that high definition narrow band imaging (NBI) colonoscopy compared to high definition white light colonoscopy will detect an increased number of nonpolypoid (flat and depressed) colorectal neoplasm.
- Conditions
- Colorectal Neoplasms, Colonic Polyps, Colorectal Cancer
- Trial name
- NBI (NCT01310699)
- Testing
- Olympus Colonoscope CFHQ190AL
- Where
- 3 sites in United States
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Hearing Loss, Noise-Induced
Noise Exposure and Near-Infrared Light
The primary objective of this work is to determine the effect noise has on the auditory system (both auditory health and performance) and also the degree to which the effect of pre-noise therapy such as Near Infrared (NIR) light…
- Trial name
- NCT03834714
- Testing
- Near Infrared Light, Noise Stimulus
- Where
- 3 sites in United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Miami
Lipid Tear Deficiency (Disorder), Dry Eye Disease
Changes in Tear Lipid Layer Thickness After Short Exposure to Light Emitting Diode Displays
Video display terminals (VDTs) are ubiquitous, and engagement in digital screens has grown substantially across all age groups worldwide. Prolonged exposure to VDTs is associated with the development of various health problems.
- Trial name
- NCT05003128
- Testing
- LED screen (InnoLux, Taiwan)
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Multiple Myeloma, Amyloidosis
Study of Captisol Enabled Melphalan and Pharmacokinetics for Patients With Multiple Myeloma or Light Chain Amyloidosis That Are Receiving an Autologous Transplant.
Captisol Enabled Melphalan, is a new formulation of the standard of care melphalan chemotherapy that in packaged in an inactive substance that is believed to help the chemotherapy be more stable (meaning that it doesn't lose its…
- Trial name
- NCT02909036
- Testing
- Melphalan, Pegfilgrastim, Autologous Hematopoietic Progenitor Cell Transplant
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Rib Fractures, Pain, Acute
Blue Light as an Anti-inflammatory and Analgesic Strategy in Thoracic Trauma
The main goal of this clinical trial is to learn if light therapy improves pain and inflammation in adults with painful rib fractures.
- Trial name
- BLAASTT (NCT06626334)
- Testing
- Bright Blue Light, Bright Full-Spectrum (White) Light, Usual Ambient Light
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Rebecca E Kotcher, MD
Sleep Disorder Circadian Rhythm, Delayed Sleep Phase Type
SleepHelsinki! CIRCADIAN SLEEP REGULATION IN ADOLESCENCE
Adolescence associates with alterations in sleep-wake organization, such as later circadian phase preference. Simultaneously external pressures, such as evening-driven social activities increase.
- Trial name
- SleepHel (NCT02964598)
- Testing
- Gamified intervention, Sleep coaching, Bright light
- Where
- Finland
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Photodermatoses
The Effects of Visible Light on the Skin After Administration of Oral Polypodium Leucotomos
Polypodium Leucotomos Extract (PLE) is a tropical fern that has antioxidative, photoprotective, chemoprotective, anti-inflammatory, and immunomodulatory properties.
- Trial name
- NCT02904798
- Testing
- Polypodium Leucotomos
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.