Clinical trials: Light Therapy
Healing Surgical Wounds, Pain Measurement
Effects of Laser Stimulation on Wound Healing of Human Palatal Tissue
The purpose of this study is to assess the effects of photobiomodulation (PBM) with an Er:YAG laser on the palatal donor site following subepithelial connective tissue graft (SECTG) surgery.
- Trial name
- NCT03741062
- Testing
- J. Morita AdvErl Evo Er:YAG laser, Control
- Where
- Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Primary Dysmenorrhea
Low-level Light Therapy for Primary Dysmenorrhea
The purpose of this study was to evaluate the effectiveness of a self-therapeutic approach of skin adhesive low-level light therapy (LLLT) in females with primary dysmenorrhea (PD).
- Trial name
- NCT02026206
- Testing
- low-level light therapy
- Where
- 2 sites in South Korea
- Volunteers
- 88 people
- Sponsor
- Pusan National University
Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders
Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer
RATIONALE: Methadone, morphine, or oxycodone may help relieve pain caused by cancer. It is not yet known whether methadone is more effective than morphine or oxycodone in treating pain in patients with cancer.
- Conditions
- Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders, Leukemia, Lymphoma
- Trial name
- NCT00726830
- Testing
- methadone hydrochloride, morphine sulfate, oxycodone hydrochloride
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- M.D. Anderson Cancer Center
Acne Vulgaris, Acne
Safety and Preliminary Efficacy of Combination Therapy for the Treatment of Acne Vulgaris
Acne vulgaris is a multifactorial, highly prevalent dermatologic condition that results in visible lesions that can be quite disfiguring.
- Trial name
- NCT02431494
- Testing
- Blue light phototherapy, Microcurrent therapy, Combination of BLP and Microcurrent
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Nova Southeastern University
Body Contouring
Study of the Effectiveness of Green Diode Laser Light on Body Shaping
The purpose of this study is to determine if 532nm green diode laser light is effective in body contouring of the waist, hips and thighs.
- Trial name
- NCT01292538
- Testing
- Erchonia GLS
- Where
- 2 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Erchonia Corporation
Mild Cognitive Impairment
Rhythmic Light Therapy for Alzheimer's Disease Patients
The investigator will investigate how light delivering 40 hertz (Hz) affects subjective sleep and cognition in a controlled laboratory study.
- Trial name
- NCT05015478
- Testing
- Tailored Rhythmic Lighting Intervention
- Where
- 2 sites in United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Anemia, Leukemia
Darbepoetin Alfa With or Without Iron in Treating Anemia Caused By Chemotherapy in Patients With Cancer
RATIONALE: Darbepoetin alfa may cause the body to make more red blood cells. Red blood cells contain iron that is needed to carry oxygen to the tissues.
- Conditions
- Anemia, Leukemia, Lymphoma, Lymphoproliferative Disorder
- Trial name
- NCT00661999
- Testing
- darbepoetin alfa, ferrous sulfate, sodium ferric gluconate complex in sucrose
- Where
- 2 sites in United States
- Volunteers
- 502 people
- Sponsor
- Mayo Clinic
Chronic Plaque Psoriasis
ChangE From Any Systemic psoriasiS therapY to Raptiva
To assess the safety of transitioning subjects to Raptiva therapy from standard oral systemic or phototherapy by overlapping with Raptiva whilst tapering the initial systemic therapy or phototherapy dose.
- Trial name
- EASY (NCT00697593)
- Testing
- Efalizumab - anti CD11a recombinant human monoclonal antibody (mAb)
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Delirium
Prevention of Delirium After Bone Marrow Transplantation
The purpose of this study is to find out if using bright light sessions during bone marrow transplant can prevent people from developing confusion also known as delirium.
- Trial name
- NCT01700816
- Testing
- Bright light therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Onychomycosis
Study of Erchonia Low Level Laser Light Therapy to Treat Toenail Fungus
The purpose of this study is to determine whether low level laser light therapy is effective in the treatment of toenail onychomycosis.
- Trial name
- NCT02242019
- Testing
- Erchonia LUNULA
- Where
- Ireland
- Volunteers
- 109 people
- Sponsor
- Erchonia Corporation
Pain
Opioid Sparing Potential of Light-Induced Analgesia
This is a pilot trial testing the potential opioid-sparing analgesic effect of a novel non-pharmacological treatment using visualized light spectrums. Preclinical findings have shown such treatments to alter pain perception.
- Trial name
- NCT03890419
- Testing
- Green light, Clear light, Blue Light
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Duke University
Shoulder Pain, Neck Pain
Low Level Laser Light Therapy and Chronic Neck and Shoulder Pain
The purpose of this study was to determine whether the application of low level laser light therapy to the neck and shoulder region is effective in reducing chronic neck and shoulder pain of musculoskeletal origin.
- Conditions
- Shoulder Pain, Neck Pain, Musculoskeletal Pain, Musculoskeletal Strain
- Trial name
- NCT00929305
- Testing
- Erchonia PL2000
- Volunteers
- 100 people
- Sponsor
- Erchonia Corporation
Psoriasis
Excimer Laser Phototherapy Outcomes in the Treatment of Psoriasis
The purpose of this study is to determine the best dosing strategy when using Excimer Laser to treat plaque-type psoriasis. In this study, half of the body's psoriasis will be treated with a new dosing strategy, and the other…
- Trial name
- Photos (NCT02294981)
- Testing
- Excimer laser phototherapy
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, San Francisco
Progressive Keratoconus
Corneal Collagen Cross-linking for Progressive Keratoconus
Prospective, randomized multicenter study to determine the safety and effectiveness of performing cornea collagen cross-linking (CXL) using riboflavin and UVA light in eyes with progressive keratoconus.
- Trial name
- CXL (NCT00647699)
- Testing
- riboflavin ophthalmic solution, UVA Irradiation
- Where
- 10 sites in United States
- Volunteers
- 147 people
- Sponsor
- Glaukos Corporation
Posttraumatic Stress Disorder
Bright Light: An Adjunct Treatment for Combat Posttraumatic Stress Disorder (PTSD)
The investigators are testing novel treatments for combat PTSD: bright light exposure and negation ion exposure.
- Trial name
- NCT00701064
- Testing
- Bright Light Exposure, Negative Ion Generator
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- VA Office of Research and Development
Fetal Growth Retardation
Study Aimed At Improving Height With Genotonorm In Children Born Little And/Or Light With Growth Retardation At The Age
To estimate the percentage of children with serum IGF-1 > 2 standard deviation (compared to a child of the same gender and age and without growth hormone (GH) deficiency) 9 months and 12 months after initiation of GH treatment.
- Trial name
- NCT00174252
- Testing
- Genotonorm (Somatropin)
- Where
- 22 sites in France
- Volunteers
- 57 people
- Sponsor
- Pfizer
Amyloidosis
A Safety Study of GSK3039294 in Healthy Volunteers and Patients With Systemic Amyloidosis
GSK3039294 has been developed in order to offer an orally available alternative to parenteral CPHPC (GSK2315698 [metabolite of GSK3039294]) for plasma serum amyloid P component (SAP) depletion prior to use of anti SAP monoclonal…
- Trial name
- NCT02603172
- Testing
- GSK3039294
- Where
- United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Parkinson Disease, Sleep Disorder
Light Therapy for PD - Dose Selection
This study aims to determine the most effective dose of light therapy to improve sleep in people with Parkinson's Disease. Four groups of participants will receive bright-white or dim-red light therapy at different times…
- Conditions
- Parkinson Disease, Sleep Disorder, Fatigue
- Trial name
- NCT04291014
- Testing
- SunRay Light Boxes
- Where
- 25 sites in United States
- Volunteers
- 203 people
- Sponsor
- Massachusetts General Hospital
Alzheimer Disease
Caring Light Project for Family Caregivers
Caring Light is designed to help caregivers of someone with Alzheimer's Disease and related dementia to cope with the difficulties related to caregiving, reduce stress, and improve quality of life.
- Trial name
- NCT04517877
- Testing
- Caring Response App, Traditional Educational/Resources Program
- Where
- United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Photozig, Inc.
Actinic Keratosis
Metvix PDT Versus Vehicle PDT With Aktilite CL128 Lamp in Patients With Actinic Keratosis on the Face and Scalp
The purpose of this study was to compare the efficacy of Photodynamic Therapy (PDT) with methyl aminolevulinate (MAL) cream to PDT with vehicle cream, using the Light-emitting diode (LED) light source Aktilite CL128, in treatment…
- Trial name
- NCT00304239
- Testing
- Metvix-PDT, Vehicle-PDT
- Where
- 11 sites in United States, Germany
- Volunteers
- 131 people
- Sponsor
- Galderma R&D