Clinical trials: Limb Pain
Pain Management
Rectroclavicular Block in Orthopedic Surgey
The ultrasound-guided retroclavicular approach to the infraclavicular region (RAPTIR) brachial plexus block has gained popularity as a relatively easy-to-perform nerve block that provides reliable and dense anesthesia to the…
- Trial name
- NCT06406647
- Testing
- retrocalvicular block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- New Valley University
Complex Regional Pain Syndromes
Thoracic Paraspinal Soft Tissue Mobilizations in Treatment of Patients With Upper Limb Complex Regional Pain Syndrome
This study examines the prevalence of trigger points in muscles in the thorax in upper limb Complex Regional Pain Syndrome (CRPS) patients, compared to healthy subjects.
- Trial name
- NCT03111225
- Testing
- massage
- Where
- Israel
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Reuth Rehabilitation Hospital
Multiple Sclerosis, Muscle Spasticity
Intermittent Theta-Burst Stimulation for Lower-Limb Spasticity and Pain in Multiple Sclerosis
Spasticity and neuropathic pain are frequent and disabling symptoms of multiple sclerosis. Intermittent theta-burst stimulation (iTBS) is a non-invasive neuromodulation technique that may modulate cortical and corticospinal…
- Conditions
- Multiple Sclerosis, Muscle Spasticity, Neuropathic Pain
- Trial name
- TMS-SPASMS (NCT07786506)
- Testing
- Active Intermittent Theta-Burst Stimulation (iTBS)
- Where
- Slovakia
- Volunteers
- 40 people
- Sponsor
- Comenius University
Pain Management
A Non-invasive Intervention (BreEStim) for Management of Phantom Limb Pain (PLP) After Limb Amputation (Experiment 3)
The purpose of this study is to compare the effectiveness of innovative intervention of breathing controlled electrical stimulation (BreEStim) and conventional electrical stimulation (EStim) in management of neuropathic phantom…
- Trial name
- NCT04751526
- Testing
- BreEStim 240, EStim 240
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- The University of Texas Health Science Center, Houston
Postoperative Pain
Effect of Psychosocial and Psychophysical Factors and Preemptive Analgesia on Postoperative Pain in Upper Limb Surgery
The purpose of this study is to define the role of preemptive systemic analgesia in combination with regional anesthetic techniques on postoperative pain following upper limb surgery in different subgroups of patients with…
- Trial name
- NCT05248152
- Testing
- Paracetamol and Ibuprofen, Pregabalin 150mg
- Where
- Slovenia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Pediatric Patients, Orthopedic Surgery
Nociception Level Index as a Verbal Tool of Pain in Children
60 children under 6 years old, scheduled for orthopedic surgery for limb fracture or neuromuscular and bone deformities will be randomized by closed envelope method into two groups (n=30) either receiving standard pain management…
- Conditions
- Pediatric Patients, Orthopedic Surgery, Extremity Fractures Lower, Extremity Fractures Upper
- Trial name
- NCT05716243
- Testing
- The nociception level index monitorization, The nociception level index measurement;postoperative
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Haseki Training and Research Hospital
Complex Regional Pain Syndromes
Pregabalin Versus Placebo as an Add on for Complex Regional Pain Syndrome (CPRS) of the Upper Limb Managed by Stellate Ganglion Block (The PREGA Study)
The purpose of this study is to assess the efficacy of pregabalin in patients with complex regional pain syndrome Type I and to determine whether it provides clinically significant pain relief and whether it improves functioning…
- Trial name
- PREGA (NCT00891397)
- Testing
- Pregabalin
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- McMaster University
Hip Injuries, Hip Dislocation
Does Limb Pre-Conditioning Reduce Pain After Hip Arthroscopy
The purpose of this study is to determine if the utilization of Ischemic Pre-Conditioning 24-hours prior to hip arthroscopy decreases patient's post-operative pain and opioid consumption.
- Conditions
- Hip Injuries, Hip Dislocation, Hip Fractures
- Trial name
- NCT04925791
- Testing
- standardized pre-conditioning treatment, Partial occlusion
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Critical Limb Ischemia, Peripheral Vascular Disease
Study of Remodulin in Patients With Critical Limb Ischemia With No Planned Revascularization Procedures
The purpose of this study is to assess and compare the safety of continuous and daily subcutaneous Remodulin therapy in patients with critical limb ischemia (CLI) with no planned vascular interventional procedures; and to…
- Conditions
- Critical Limb Ischemia, Peripheral Vascular Disease, Foot Ulcers, Rest Leg Pain
- Trial name
- NCT00060996
- Testing
- Remodulin® (treprostinil sodium) Injection
- Where
- 7 sites in United States
- Volunteers
- 30 people
- Sponsor
- United Therapeutics
Pain Threshold, Myofascial Trigger Point
Comparative Effects of Myofascial Induction Therapy Versus Gastrocnemius Pressure Release Treatment on Trigger Point Pressure Pain Threshold in Proximal Muscles and Ankle Range of Motion.
The aim of the study is to test the effect of myofascial induction and pre-pressure release of the grastrocnemius muscle on the proximal musculature: biceps femoris, flexor digitorum brevis and extensor digitorum grandus on the…
- Conditions
- Pain Threshold, Myofascial Trigger Point, Manual Therapy, Range of Motion
- Trial name
- NCT06499441
- Testing
- Myofascial induction in gastrocnemius, Preassure release
- Where
- Spain
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Mayuben Private Clinic
Amputation Neuroma
Regenerative Peripheral Nerve Interfaces for the Treatment of Painful Neuromas in Major Limb Amputees
The Regenerative Peripheral Nerve Interface (RPNI) is a novel strategy to prevent neuroma formation in transected peripheral nerves.
- Trial name
- NCT07285486
- Testing
- Amputation with Regenerative Peripheral Nerve Interfaces (RPNI), Amputation Without RPNI
- Where
- 2 sites in United States
- Volunteers
- 132 people
- Sponsor
- University of Michigan
Knee Osteoarthritis
Effectiveness of Platelet-rich Plasma Treatment of Knee Osteoarthritis
Osteoarthritis (OA) is a disease that affects the joints of the body, causing pain, stiffness, and reduced mobility. To treat knee OA, a therapy called platelet-rich plasma (PRP) is used, which involves making a concentrated…
- Trial name
- NCT05825105
- Testing
- Platelet-Rich Plasma
- Where
- Argentina
- Volunteers
- 111 people
- Sponsor
- Universidad Nacional de Entre Rios
Pes Planus
Exercises for Pes Planus
Pes planus is a musculoskeletal syndrome in which the medial longitudinal arch (MLA) of the foot is reduced or flattened. It results from a combination of static and dynamic abnormalities.
- Trial name
- NCT07123753
- Testing
- EXERCİSE
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Gaziantep Islam Science and Technology University
Complex Regional Pain Syndromes
Thoracic Sympathetic Ganglion Block With Botulinum Toxin Type A
Thoracic sympathetic ganglion block is a percutaneous procedure that paralyzes the action of sympathetic nerves transiently by injecting a local anesthetic around the ganglion.
- Trial name
- NCT06470581
- Testing
- Botulinum toxin A
- Volunteers
- 78 people
- Sponsor
- Seoul National University
Pain, Chronic, Upper Extremity Problem
Upper Extremity paın and Ultrasound Use
The relationship between perinatologists' ultrasound use and upper limb joint pain will be evaluated.
- Trial name
- NCT04477135
- Testing
- upper extremity pain, ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Nefise Nazlı YENIGUL
Amputation
Targeted Muscle Reinnervation Study (TMR)
The purpose of this study is to examine the effect of targeted muscle reinnervation on the outcomes of amputees at a level 1 trauma center.
- Trial name
- TMR (NCT05408520)
- Testing
- Targeted Muscle Reinnervation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Arizona
Epidural, Oxycodone
Epidural Oxycodone for Pain Management for Lower Limb Amputation
The aim of this study is to evaluate the effect of epidural oxycodone for pain management after lower limb amputation.
- Conditions
- Epidural, Oxycodone, Pain, Lower Limb Amputation
- Trial name
- NCT06276179
- Testing
- Oxycodone, Bupivacaine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Kafrelsheikh University
Piriformis Syndrome
Graston vs Manual Myofascial Release Technique in Piriformis Syndrome.
The objective of our study is to compare the effects of Graston and manual myofascial release technique on pain, muscle length and functional status in patients with Piriformis syndrome.
- Trial name
- NCT04588779
- Testing
- Graston, Manual myofascial release
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Arthralgia, Joint Stiffness
Impact of 'Recovery' Footwear on Lower Extremity Comfort and Biomechanics
The goal of this study is to understand the impact of wearing shoes with a compliant, energy absorbing midsole material, outside of athletic training sessions on the mechanics of movement, performance, and perceived joint pain…
- Conditions
- Arthralgia, Joint Stiffness, Gait Mechanics
- Trial name
- NCT04830540
- Testing
- OOFOS Recovery Footwear
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Postoperative Pain, Lower Limb Injury
Block Duration After Spinal Block and iv Dexamethasone.
It has been largely demonstrated that iv dexamethasone prolongs the duration of analgesia after peripheral nerve block. However, data are missing regarding the duration of analgesia after spinal block.
- Trial name
- NCT03527576
- Testing
- Dexamethasone, NaCl 0.0308 MEQ/ML Injectable Solution
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Eric Albrecht