Clinical trials: Limb Salvage
Complex Regional Pain Syndrome Type I
Longitudinal Follow-up Study About Complex Regional Pain Syndrome (CRPS) Patients
Complex regional pain syndrome (CRPS) is a post-traumatic chronic pain condition characterized by pain and other symptoms typically affecting a distal limb.
- Trial name
- NCT04703647
- Testing
- Administration of questionnaires for prospective group, Blood samples for prospective group, Blood samples for control group
- Where
- Switzerland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Clinique Romande de Readaptation
Stroke, Stroke, Ischemic
Efficacy of REMO Training for Hand Motor Recovery After Stroke
Upper limb motor impairment is one of the most common sequelae after stroke. Indeed, the recovery of upper limb sensory-motor functions remains one of the most important goals in stroke rehabilitation.
- Conditions
- Stroke, Stroke, Ischemic, Stroke Hemorrhagic, Stroke Sequelae
- Trial name
- REMO (NCT05815368)
- Testing
- REMO, Task-Oriented Training
- Where
- Italy
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Stroke
Neural Correlates of Lower Extremity Motor Recovery in Stroke Patients: Longitudinal Diffusion Spectrum Imaging Studies
To investigate the relationship between the integrity of the white matter, including the corticospinal tracts and the corpus callosum, with the recovery of lower extremity function in patients with cerebral stroke at the subacute…
- Trial name
- NCT00407628
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Obesity, Morbid
Laparoscopic Sleeve Gastrectomy-Induced Decline in Plasma Asprosin and Its Association With Metabolic Recovery
the present study aimed to systematically assess the changes in plasma asprosin levels at 3, 6, and 12 months after LSG, to explore the relationships between asprosin dynamics and key metabolic parameters, including body mass…
- Trial name
- NCT07008274
- Testing
- surgery
- Where
- China
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Northern Jiangsu People's Hospital
Muscle Atrophy, Proximal, Muscle Atrophy
Ultrasound for Rectus Femoris Measurement
Postoperative protocols for orthopedic procedures on the lower limb often require a period of immobilization to protect the surgical site.
- Conditions
- Muscle Atrophy, Proximal, Muscle Atrophy, ACL Tear, Quadriceps Muscle Atrophy
- Trial name
- NCT04105816
- Testing
- 892.1550 Ultrasonic pulsed doppler imaging system, Thigh circumference measurement
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Robert Westermann
Healthy Tennis Players
The Effect of Recovery Training on Lower Extremity Explosive Strength in Tennis Players
This study was designed to examine the effects of recovery training on lower extremity explosive strength performance in tennis players.
- Trial name
- NCT07306351
- Testing
- Recovery Training Group
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Biruni University
Stroke
Combine Transcranial Direct Current Stimulation and Neuromuscular Electrical Stimulation on Stroke Patients
Transcranial direct current stimulation (tDCS) has been shown not only to improve motor function but also increase cortical excitability and neural plasticity.
- Trial name
- NCT02821884
- Testing
- Combination of tDCS and NMES
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Stroke
Interference During Motor Learning of Different Degrees of Freedom in the Paretic Upper Extremity of People With Stroke
Post-stroke rehabilitation of the upper extremity is a challenge in neurorehabilitation. Selective training of different degrees of freedom (training of specific monoarticular movements and in one plane of movement of the upper…
- Trial name
- NCT06249737
- Testing
- Training
- Where
- 2 sites in Spain
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Stroke
Study of Neurophysiological Markers of Motor Recovery in Post-stroke Patients.
The aim of the study was to explore potential pathways for recovery and adaptation of neural pathways after stroke by examining electrical activity of the brain cortex and cortico-spinal excitability using transcranial magnetic…
- Trial name
- NCT06386627
- Testing
- Stimulus response task, Transcranial magnetic stimulation
- Where
- Russia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Skolkovo Institute of Science and Technology
Stroke
Monitoring Arm Recovery After Stroke (MARS)
People who have a stroke often find it hard to do the things they did before. This can be caused by problems with arm movement. One in five people do not get any arm movement back after a stroke.
- Trial name
- MARS (NCT07016295)
- Testing
- Biomechanical analysis of arm movement, Pose estimation of arm movement
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King's College London
Stroke, Ischemic
Marker for Stroke Recovery
This study aims to develop a neurophysiological marker for post-stroke participants that predicts upper extremity motor recovery in response to a standard upper extremity rehabilitation protocol of task-specific training (TST).
- Trial name
- NCT05256368
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Blood Loss, Surgical
Efficacy of Tranexamic Acid in Preventing Post Operative Blood Loss in Bone Sarcoma Patient
investigator will see the efficacy of tranexamic acid in limb salvage surgery patients which will prevent blood loss and help in conservation of blood products.
- Trial name
- NCT05427513
- Testing
- Tranexamic acid injection, normal saline
- Where
- Pakistan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre
Stroke
Interaction Between the Brain Hemispheres - Key to Motor Recovery After Stroke
Rationale: Acute stroke leaves many patients with functional deficits, of which upper extremity motor impairment is one of the most disabling.
- Trial name
- InterAct (NCT06381388)
- Testing
- cTBS
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jord Vink
Hip Fractures
Comparison of Pericapsular Nerve Group Block With Suprainguinal Fascia Compartment Block in Hip Fractures
Ultrasound-guided Supra-inguinal Fascia Iliaca compartment Block (SIFCB) and Pericapsular Nerve Group Block (PENG) are increasingly being used for postoperative analgesia for hip surgery.
- Trial name
- NCT06169462
- Testing
- PENG block, PENG block+ SIFCB
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital
Spinal Cord Injuries
Effects of Breathing Mild Bouts of Low Oxygen on Limb Mobility After Spinal Injury
Accumulating evidence suggests that repeatedly breathing low oxygen levels for brief periods (termed intermittent hypoxia) is a safe and effective treatment strategy to promote meaningful functional recovery in persons with…
- Trial name
- NCT02323945
- Testing
- AIH, Walk, Strength
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Hemiplegic Cerebral Palsy, Motor Activity
Action Observation Based Rehabilitation of Children With Unilateral Cerebral Palsy
Recent evidence suggested that Action Observation Therapy (AOT), based on observation of actions followed by immediate reproduction, could be a useful rehabilitative strategy for promoting functional recovery of children affected…
- Trial name
- NCT04088994
- Testing
- AOT Pathological Model Experimental Group, AOT Healthy Model Control Group
- Where
- Italy
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Parma
Stroke Rehabilitation
Vibratory Perturbation-based Pinch Task Training for Stroke Patients
The investigator assumed that perturbed-event-induced vibrotactile cueing enable more precision arm movement adjustment, sensory function and dexterity improvement in the spastic arm.
- Trial name
- NCT03798340
- Testing
- Vibratory perturbed task-specific movement training, Traditional task-oriented facilitation, Sensorimotor training
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Stroke
Aha BOOST Arm-hand BOOST Therapy to Enhance Recovery After Stroke: Clinical, Health Economic and Process Evaluation
The overall aim of this study is to establish the clinical- and cost-effectiveness of the arm-hand BOOST therapy when delivered on top of the usual care program in the sub-acute phase post stroke and to perform a process…
- Trial name
- AHA-BOOST (NCT06517251)
- Testing
- Arm-hand BOOST, Lower limb BOOST
- Where
- 2 sites in Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Chronic Stroke-related Upper-extremity Motor Impairment, Motor Module-guided Rehabilitation Targeting Impaired Intermuscular Coordination and Motor Recovery
Neuro-Intermuscular Coordination Enhancement (NICE) Rehabilitation Through Human-Machine Interaction in Chronic Stroke
The objective of this study is to develop Neuro-Intermuscular Coordination Enhancement (NICE) rehabilitation, a novel neuromuscular control signal-guided strategy that visually guides stroke patients to individually activate…
- Trial name
- NICE (NCT07531264)
- Testing
- Neuromuscular coordination enhancement (NICE) intervention, EMG Amplitude Biofeedback Exercise
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Houston
Stroke, Hemiparesis
Trans Auricular Vagus Nerve Stimulation (taVNS) and Robotic Training for Paralyzed Arm After Stroke
To determine whether treatment with transauricular vagus nerve stimulation (taVNS) during the training of an affected upper limb of a patient with chronic stroke on a robotic motor task alters the motor impairment.
- Trial name
- VaNSaRTS (NCT05339893)
- Testing
- In Motion Rehabilitation Robot
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northwell Health