Clinical trials: Limb Volume
Sarcoma
MRI in Pre-operative Radiotherapy for Soft Tissue Sarcoma: MISTS Study
This study will use diffusion weighted MRI (DWI MRI) and dynamic-contrast enhanced MRI (DCE MRI) techniques to detect changes in sarcoma tumour vasculature.
- Trial name
- NCT01956019
- Testing
- MRI scanning
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- The Christie NHS Foundation Trust
Physical Performance, Neuromuscular Function
Tissue Flossing and Lower Limb Neuromuscular Function
There is no study investigating different volumes, that is various sets of the configuration of tissue flossing on neuromuscular function.
- Conditions
- Physical Performance, Neuromuscular Function, Tissue Flossing, Ischemic Preconditioning
- Trial name
- MF2-TMG-CMJ (NCT05219344)
- Testing
- Tissue flossing
- Where
- Slovenia
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Amputation Stump
Characterization of Residual Limb Volume Changes in Transfemoral Amputees
This study quantifies residual limb volume fluctuations affecting transfemoral amputees due to the prosthesis doffing, physical activity, and testing time.
- Trial name
- NCT04709367
- Testing
- 3D optical scan
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Istituto Nazionale Assicurazione contro gli Infortuni sul Lavoro
Amputation
Amputee Residual Limb Volume Fluctuation
The goal of this project is a useful clinical instrument for diagnosis and treatment of residual limb volume fluctuation in individuals who use prosthetic limbs.
- Trial name
- NCT01161238
- Testing
- Monitored for limb volume
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Washington
Diurnal Residual Limb Fluid Volume Fluctuation
Accommodating for Residual Limb Fluid Volume Change
The purpose of this study is to quantify residual limb fluid volume changes between morning and afternoon hours, and to determine if fluid volume change is correlated with activity.
- Trial name
- AM-PM (NCT02124876)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Washington
Chronic Obstructive Pulmonary Disease
The Differences of Muscle Activity Between Patients With COPD and Healthy Adults
The purpose of this study attempts to investigate the differences and relationships of respiratory parameters, muscle activity, and dyspnea during ADL between patients with COPD and age-matched healthy participants.
- Trial name
- NCT04146948
- Testing
- no intervention
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Lymphedema
Pedal Pump and Leg Lymphedema
Chronic lymphedema in the lower extremities is a common problem found in older adults that can result in cellulitis, poor wound healing, venous stasis ulcers, and other comorbidities.
- Trial name
- NCT06235463
- Testing
- Osteopathic Pedal Pump, Light Touch Treatment
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Rowan University
Sarcoma
Randomised Trial of Volume of Post-operative Radiotherapy Given to Adult Patients With eXtremity Soft Tissue Sarcoma
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Giving radiation therapy after surgery may kill any tumor cells that remain after surgery.
- Trial name
- VORTEX (NCT00423618)
- Testing
- radiotherapy
- Where
- 6 sites in United Kingdom
- Volunteers
- 216 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Lymphedema Lower Extremity
Assessment of the Efficacy of the Dynamic Decongestive System in the Maintenance Phase of Lower Limb Lymphedema
The trial aims to determine whether the dynamic compression device, used in combination with elastic compression garments, is non-inferior to currently available compression devices (CACD) during the maintenance phase of…
- Trial name
- EDYDES-maint (NCT07603531)
- Testing
- Control group: Currently available compression devices, DDS group: Dynamic compression device (DDS)
- Where
- 3 sites in France, Germany
- Volunteers
- 98 people
- Sponsor
- Jean-Paul Belgrado
Lower Limb Amputation Below Knee (Injury), Diurnal Residual Limb Fluid Volume Fluctuation
An Automatically Adjusting Prosthetic Socket for People With Transtibial Amputation
People with leg amputations often experience daily changes in the size (volume) of their residual limb. These daily changes can cause a prosthesis to fit poorly. They can also cause limb problems like pain or skin breakdown.
- Trial name
- NCT05124652
- Testing
- Auto Adjusting Prosthesis
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Washington
Soft Tissue Sarcoma
Dose Reduction of Postoperative Radiation for Soft Tissue Sarcoma of the Arms and Legs
The investigators are doing this study to find out whether lowering the dose of postoperative radiation therapy and targeting a smaller area of tissue for treatment is as effective as the standard dose and volume of radiation…
- Trial name
- NCT04288375
- Testing
- Intensity-modulated radiation therapy (IMRT)
- Where
- 7 sites in United States
- Volunteers
- 65 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Knee Arthropathy
Effect of NLR and MPV on Early Postoperative Outcome in Lower Extremity Arthroplasty Operations
In the planned study the investigators want to evaluate the relation between postoperative complications and minor/ major morbidities, mortality and Mean Platelet Volume (MPV) and Neutrophil/ lymphocyte (N/L) ratio.
- Trial name
- NCT03148951
- Where
- Turkey (Türkiye)
- Volunteers
- 754 people
- Sponsor
- Akdeniz University
Lipedema, Exercise Therapy
Investigation of the Effects of High-Intensity Interval Exercise and Moderate-Intensity Continuous Exercise on Limb Volume, Functional Capacity, and Quality of Life in Patients With Lipedema
This randomized controlled clinical study aims to investigate and compare the effects of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT), when combined with intermittent pneumatic…
- Conditions
- Lipedema, Exercise Therapy, High Intensity Interval Training
- Trial name
- NCT07319611
- Testing
- Intermittent Pneumatic Compression (IPC), Home-Based Walking Program, High-Intensity Interval Training (HIIT)
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Marmara University
Non-Insulin-Dependent Diabetes Mellitus
Study In Patients With Type 2 Diabetes Who Are Taking Metformin And Sulfonylurea, Metformin And Insulin, Or Insulin
This study will use Magnetic Resonance Imaging (MRI) techniques to evaluate changes in fluid volume in the lower legs of diabetic patients who add either pioglitazone or placebo to their current diabetic regimen.
- Trial name
- NCT00269061
- Testing
- pioglitazone
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- GlaxoSmithKline
Evaluation of a New Prosthetic Socket Liner Material
Evaluation of the Development of an Advanced, Conformable Prosthetic Socket, Study II
The purpose of this study is to work with prosthetists to fit the novel conformable socket material developed by Infoscitex, to subjects, and determine if it is a viable alternative to current prosthetic socket liners.
- Trial name
- NCT01455324
- Testing
- Novel conformable woven inner socket
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Infoscitex Corporation
Analgesia, Postoperative, Complications of Treatment
Effectiveness of Low Volume Versus High Volume of Local Anesthetic in Ultrasound Guided Combined Supraclavicular and Interscalene Block for Upper Limb Surgery
The aim of this study is to evaluate the effectiveness of low versus high volumes of local anesthetic in ultrasound-guided combined supraclavicular block (SCB) and interscalene block (ISB) for upper limb surgery.
- Trial name
- NCT07028957
- Testing
- Group A; Low volume local anesthetic in Ultrasound guided combined Supraclavicular and Interscalene block for Upper limb surgery, Group B; High volume local anesthetics (30-40ml) ultrasound guided combined Supraclavicular Block (SCB) and Interscalene Block (ISB)
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology
Cerebral Palsy
Unilateral Versus Bilateral Lower-Limb Plyometric Training in Children With Cerebral Palsy
This study was set out to compare the effect of paretic-limb-only plyometric training versus double-limb training on balance capability and gait symmetry in adolescents with unilateral cerebral palsy (U-CP).
- Trial name
- NCT05302102
- Testing
- Unilateral plyometric training, Bilateral plyometric training, Standard physical therapy
- Where
- Saudi Arabia
- Volunteers
- 69 people
- Sponsor
- Cairo University
Transtibial Amputee
Bioimpedance as a Diagnostic Tool for Assessing the Need for Socket Modification in Transtibial Amputees
The purpose of the proposed study is to conduct research on individuals with lower limb amputation, evaluating if residual limb fluid volume data collected using a novel non-invasive device is beneficial towards prosthetic…
- Trial name
- NCT03164356
- Testing
- Bioimpedance monitor
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Washington
Lymphedema
Two Pneumatic Compression Devices in the Treatment of Lower Extremity Lymphedema
The treatment of lymphedema has been a major focus of attention for physicians and scientists for several decades. At this time, no successful techniques have been developed to prevent lymphedema, and therefore, a great deal of…
- Trial name
- ACE (NCT01239160)
- Testing
- Flexitouch System, Hydroven FPR
- Where
- 22 sites in United States, Australia and 1 more
- Volunteers
- 238 people
- Sponsor
- Tactile Medical
Lymphedema, Lower Limb
Correlation Between Volume and Pain in Lower Limbs Lymphoedema
The vascular physiotherapy department of the UCL University Clinics of Mont-Godinne specializes in the physiotherapeutic management of lymphoedema.
- Trial name
- NCT06145204
- Testing
- questionnaire
- Where
- Belgium
- Volunteers
- 79 people
- Sponsor
- University Hospital of Mont-Godinne