Clinical trials: Linear Growth
Neurodevelopment Outcome, Linear Growth
Micronutrient Enhancement for Development and Health in Adolescents - The MEDHA Study
MEDHA is a randomized controlled trial among 10-18 year old girls to examine the use-case of the United Nations International Multiple Micronutrient Antenatal Preparation (UNIMMAP) multiple micronutrient supplement (MMS)…
- Conditions
- Neurodevelopment Outcome, Linear Growth, Micronutrient Status, Bone Mineral Density
- Trial name
- MEDHA (NCT07695883)
- Testing
- Iron (60 mg)- folic acid (400 ug) [IFA], Multiple micronutrient supplement [MMS], Multiple micronutrient supplement Plus [MMS+]
- Where
- Bangladesh
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Skin Health, Collagen Supplementation
IMPACT OF SUPPLEMENTATION WITH LOW MOLECULAR WEIGHT HYDROLYZED COLLAGEN AND VERISOL ON THE EXPRESSION OF LINES, SKIN QUALITY, AND LEVELS OF KLOTHO, VEGF, AND TGF-BETA IN THE EYE REGION
Skin is the largest organ of the human body and performs various vital functions, including protection against external agents, regulation of body temperature, and sensory perception.
- Conditions
- Skin Health, Collagen Supplementation, Growth Factors
- Trial name
- NCT06971029
- Testing
- Supplementation with Verisol®, Supplementation with Peptech® 2.5G, Supplementation with Peptech® 10.0G
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Stunting
Food-based Approach Development to Fulfil Amino Acid Gap by Considering the Intestinal Permeability of Children
This study will be comprised of 2 phases. Phase 1 study is a comparative cross-sectional study which will be conducted among children aged 12-24 months living in agricultural area.
- Trial name
- NCT04157413
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Nia Novita Wirawan
Diarrhea, Stunting
Zinc-MNP Trial for Prevention of Diarrhea and Promotion of Linear Growth
This is a randomized, double-blind, community-based efficacy trial of different doses, forms, and frequencies of zinc supplementation for the prevention of diarrhea and promotion of linear growth among children 9-11 months of age…
- Trial name
- NCT03406793
- Testing
- Standard MNP, High zinc, low iron MNP, High zinc, low/no iron on alternating days
- Where
- Bangladesh
- Volunteers
- 2,886 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Growth Disorders, Infant Malnutrition
Effect of a Complementary Food Supplement on Growth and Morbidity of Ghanaian Infants
Prevention of malnutrition in infants and children requires access and intake of nutritious food starting at birth with exclusive breastfeeding for the first 6 months of life, breastfeeding in combination with complementary foods…
- Conditions
- Growth Disorders, Infant Malnutrition, Micronutrient Deficiency, Protein Malnutrition
- Trial name
- TRIUMF (NCT03181178)
- Testing
- Macro-micronutrient complementary food supplement, A micronutrient powder, Nutrition education
- Volunteers
- 1,204 people, healthy volunteers welcome
- Sponsor
- Nevin Scrimshaw International Nutrition Foundation
Non-small Cell Lung Cancer
Furmonertinib Monotherapy and Combination Therapy in Advanced EGFR Mutant NSCLC With Uncleared ctDNA
EGFR mutation positive advanced NSCLC patients with uncleared ctDNA have poor prognosis, whether they can benefit from combination therapy has not been reported.
- Trial name
- FOCUS-C (NCT05334277)
- Testing
- Furmonertinib, Furmonertinib/Pemetrexed/Carboplatin, Furmonertinib/Pemetrexed/Carboplatin/Bevacizumab
- Where
- 26 sites in China
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Pneumonia, Diarrhea
Azithromycin to Prevent Post-discharge Morbidity and Mortality in Kenyan Children
Children hospitalized with severe illness in sub-Saharan Africa are at high risk of morbidity and mortality following discharge from hospital.
- Conditions
- Pneumonia, Diarrhea, Malaria, Co-infection
- Trial name
- Toto Bora (NCT02414399)
- Testing
- Azithromycin
- Where
- Kenya
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Washington
Birth Weight, Pregnancy Preterm
Maternal EED and Aflatoxin Birth Outcomes Study Uganda
This prospective cohort study focuses on the relationship between maternal environmental enteric dysfunction (EED) and maternal aflatoxin B1 exposure and birth outcomes, particularly infant anthropometry and gestational age, in…
- Conditions
- Birth Weight, Pregnancy Preterm, Aflatoxins Toxicity, Inflammatory Response
- Trial name
- NCT03429257
- Testing
- Exposures of interest: Maternal EED and Aflatoxin Exposure
- Where
- Uganda
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Tufts University
Gut Microbiome, Linear Growth
Effects of Complementary Feeding on Infant Growth and Gut Health
This study plans to learn more about how consuming different foods during the time of early complementary feeding (~5 to 12 months) affects growth and the development of bacteria living inside your baby's gut through school-age.
- Trial name
- MINT (NCT05012930)
- Testing
- Baby Foods - Meat, Baby Foods - Dairy, Baby Foods - Plant
- Where
- United States
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Malnutrition
Preventing Malnutrition in Children Under Two Years of Age Approach
A study conducted by IFPRI in Haiti provided the first programmatic evidence, using a cluster randomized evaluation design, that preventing child undernutrition in children under two years of age (PM2A) through an integrated…
- Trial name
- NCT01072279
- Testing
- Tubaramure (Burundi), Procomida (Guatemala)
- Where
- 2 sites in Burundi, Guatemala
- Volunteers
- 16,895 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Linear Growth
Efficacy of Providing Eggs as an Early Complementary Food to Promote Child Growth
This study will investigate the efficacy of providing one chicken egg per day for a period of 6 months, beginning at the age of 6 to <9 months on the growth, motor development, micronutrient, and morbidity status of infants from…
- Trial name
- NCT05168085
- Testing
- Eggs
- Where
- South Africa
- Volunteers
- 655 people, healthy volunteers welcome
- Sponsor
- North-West University, South Africa
Adolescent Development, Stunting
The Nash-wo-Numa (Childhood Growth & Development) Study
The proposed study will be a cross-sectional study in the District of Matiari, Pakistan. Children ages 9-15 years will be identified from a Matiari District household census scheduled being conducted from December 2016- to May…
- Conditions
- Adolescent Development, Stunting, Depression, Micronutrient Deficiency
- Trial name
- NCT03647553
- Where
- Pakistan
- Volunteers
- 1,385 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Birth Length, Linear Growth
Sustainable Intervention of Supplementation to Improve Kid's Growth Study
Our earlier research has highlighted a high prevalence of anaemia, micronutrient deficiencies, and impaired infant growth among lactating women and infants in Sumedang district, West Java, Indonesia that were associated with…
- Conditions
- Birth Length, Linear Growth, Micronutrients, Dietary Intakes
- Trial name
- SISTIK-G (NCT04564222)
- Testing
- Micronutrient Enriched Crackers (MECs)
- Where
- Indonesia
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- SEAMEO Regional Centre for Food and Nutrition
Stunting, Anemia
Linear Programming Approach to Develop Local Specific Food-based Complementary Feeding Recommendation
Stunting and anemia amongst under-two children are attributable to poor nutrient intakes. The study evaluates the effectiveness of nutrition education on local specific food-based complementary feeding recommendation (CFR) to…
- Conditions
- Stunting, Anemia, Complementary Feeding Recommendation, Linear Programming
- Trial name
- NCT03895164
- Testing
- Enhanced NE, Standard NE
- Where
- 2 sites in Indonesia
- Volunteers
- 926 people, healthy volunteers welcome
- Sponsor
- SEAMEO Regional Centre for Food and Nutrition
Complementary Feeding, Linear Programming
Optimized Complementary Feeding With or Without Home Fortification Prevents Decrease of Micronutrient and Growth
Malnourished among under-five children characterized by growth faltering is a public health concern in Indonesia. It requires serious action from the governments because of the prevalence of underweight, stunting, and wasting are…
- Conditions
- Complementary Feeding, Linear Programming, Nutritional Status, Micronutrient Deficiency
- Trial name
- NCT03891589
- Testing
- Nutritional education program, Home fortification (Taburia)
- Where
- Indonesia
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Udayana University
At Risk or Stunted Children
Nutrition Intervention of Complementary Milk Feeding to Improve Linear Growth of at Risk and Stunted Children
This is a non-randomized open label 6 months intervention study that aims to assess the effectiveness of consuming milk daily for 6 months will improve the linear growth rate of children aged 12-36 months.
- Trial name
- NCT05670002
- Testing
- Milk supplement
- Where
- Malaysia
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- FrieslandCampina
Malnutrition
Prevention of Linear Growth Failure in Infants and Young Children With Lipid-based Nutrient Supplements (iLiNS-DOSE)
The use of lipid-based nutrients (LNS), such as Nutributter or fortified spread (FS), have been associated with improved growth and development outcomes among infants in Ghana and Malawi.
- Trial name
- iLiNS-DOSE (NCT00945698)
- Testing
- Lipid-based nutrient supplement, 10gM, Lipid-based nutrient supplement, 20gM, Lipid-based Nutrient Supplement, 20gNoM
- Where
- Malawi
- Volunteers
- 1,920 people, healthy volunteers welcome
- Sponsor
- Tampere University
Stunting, Birth Weight
Aflatoxin Birth Cohort Study Nepal (AflaCohort)
The study focuses on the causal relationship between mycotoxin exposure (particularly aflatoxin B1), birth outcomes, and height for age among young children in Nepal.
- Conditions
- Stunting, Birth Weight, Birth Length, Height for Age
- Trial name
- AflaCohort (NCT03312049)
- Volunteers
- 1,675 people, healthy volunteers welcome
- Sponsor
- Tufts University
Pregnancy
Maternal Vitamin D for Infant Growth (MDIG) Trial
The primary aims of this study are: 1) to determine whether maternal prenatal vitamin D3 supplementation (4200 IU/week, 16,800 IU/week, or 28,000 IU/week) versus placebo increases or decreases infant length at 1 year of age, and…
- Trial name
- MDIG (NCT01924013)
- Testing
- Vitamin D3 (cholecalciferol)
- Where
- Bangladesh
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Premature Infants
Targeted Protein Fortification in Extremely Low Birth Weight Preterm Infants
While new innovations in the care of extremely premature infants have led to decreased morbidity and mortality, poor postnatal growth remains as a major challenge.
- Trial name
- NCT02943746
- Testing
- Standard Protein Diet, High Protein Diet
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine